DE60216239T8 - Verwendung von Cyclohexenon-Derivaten zur Herstellung eines Arzneimittels zur Behandlung von Dysurie - Google Patents

Verwendung von Cyclohexenon-Derivaten zur Herstellung eines Arzneimittels zur Behandlung von Dysurie Download PDF

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Publication number
DE60216239T8
DE60216239T8 DE60216239T DE60216239T DE60216239T8 DE 60216239 T8 DE60216239 T8 DE 60216239T8 DE 60216239 T DE60216239 T DE 60216239T DE 60216239 T DE60216239 T DE 60216239T DE 60216239 T8 DE60216239 T8 DE 60216239T8
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DE
Germany
Prior art keywords
sup
dysuria
medicament
manufacture
treatment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE60216239T
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English (en)
Other versions
DE60216239D1 (de
DE60216239T2 (de
Inventor
Masao 86 Nishi-cho Yonago-shi MIYAGAWA
Takeshi 86 Nishi-cho Yonago-shi WATANABE
Motoaki 86 Nishi-cho Yonago-shi SAITO
Luu
M. Yamada
H. Suzuki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Centre National de la Recherche Scientifique CNRS
Universite de Strasbourg
Meiji Co Ltd
Original Assignee
Meiji Dairies Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Meiji Dairies Corp filed Critical Meiji Dairies Corp
Publication of DE60216239D1 publication Critical patent/DE60216239D1/de
Application granted granted Critical
Publication of DE60216239T2 publication Critical patent/DE60216239T2/de
Publication of DE60216239T8 publication Critical patent/DE60216239T8/de
Active legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
    • C07C403/06—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by singly-bound oxygen atoms
    • C07C403/08—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by singly-bound oxygen atoms by hydroxy groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/51—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition
    • C07C45/511—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition involving transformation of singly bound oxygen functional groups to >C = O groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/56—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds
    • C07C45/57—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with oxygen as the only heteroatom
    • C07C45/59—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with oxygen as the only heteroatom in five-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/703—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups
    • C07C49/713—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups a keto group being part of a six-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Urology & Nephrology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE60216239T 2001-02-19 2002-02-15 Verwendung von Cyclohexenon-Derivaten zur Herstellung eines Arzneimittels zur Behandlung von Dysurie Active DE60216239T8 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2001041587A JP3836684B2 (ja) 2001-02-19 2001-02-19 排尿障害治療剤
JP2001041587 2001-02-19
PCT/JP2002/001292 WO2002066024A1 (en) 2001-02-19 2002-02-15 Use of cyclohexenone derivatives for the manufacture of a medicament in the treatment of dysuria

Publications (3)

Publication Number Publication Date
DE60216239D1 DE60216239D1 (de) 2007-01-04
DE60216239T2 DE60216239T2 (de) 2007-03-08
DE60216239T8 true DE60216239T8 (de) 2007-06-21

Family

ID=18904009

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60216239T Active DE60216239T8 (de) 2001-02-19 2002-02-15 Verwendung von Cyclohexenon-Derivaten zur Herstellung eines Arzneimittels zur Behandlung von Dysurie

Country Status (7)

Country Link
US (1) US6906107B2 (de)
EP (1) EP1368014B1 (de)
JP (1) JP3836684B2 (de)
AT (1) ATE345787T1 (de)
CA (1) CA2438509C (de)
DE (1) DE60216239T8 (de)
WO (1) WO2002066024A1 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4861560B2 (ja) * 2001-02-19 2012-01-25 株式会社明治 糖尿病合併症治療剤
WO2004087630A1 (en) * 2003-03-28 2004-10-14 Meiji Dairies Corporation Process for producing cyclohexenone long-chain alcohols
ATE503471T1 (de) * 2004-11-25 2011-04-15 Meiji Dairies Corp Mittel zur linderung von niereninsuffizienz
CA2595208C (en) * 2005-01-18 2013-04-23 Meiji Dairies Corporation Therapeutic agents for sensory disorders
WO2006126295A1 (ja) * 2005-05-26 2006-11-30 Meiji Dairies Corporation 糖尿病性血管障害および呼吸障害予防および／または治療剤
WO2013147072A1 (ja) * 2012-03-29 2013-10-03 大鵬薬品工業株式会社 3-(15-ヒドロキシペンタデシル)-2,4,4-トリメチル-2-シクロヘキセン-1-オンの共結晶
JP5566521B1 (ja) * 2013-09-27 2014-08-06 大鵬薬品工業株式会社 膀胱・尿道協調不全改善剤
US20170035705A1 (en) * 2015-08-04 2017-02-09 Taiho Pharmaceutical Co., Ltd. Detrusor hyperactivity with impaired contractility ameliorating agent
JP6894555B1 (ja) * 2020-07-03 2021-06-30 大鵬薬品工業株式会社 排尿症状治療剤
JP2022013721A (ja) * 2020-07-03 2022-01-18 大鵬薬品工業株式会社 排尿症状治療剤
EP4194435A1 (de) * 2020-08-07 2023-06-14 Taiho Pharmaceutical Co., Ltd. Neue cycloalkenonverbindung oder salz davon
WO2023153422A1 (ja) * 2022-02-09 2023-08-17 大鵬薬品工業株式会社 シクロヘキセノン化合物の結晶形

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6113947A (en) 1997-06-13 2000-09-05 Genentech, Inc. Controlled release microencapsulated NGF formulation
CA2299308C (en) * 1997-08-13 2008-03-25 Meiji Milk Products Co., Ltd. Cyclohexenone long-chain alcohol and medicament containing same

Also Published As

Publication number Publication date
JP3836684B2 (ja) 2006-10-25
JP2002241271A (ja) 2002-08-28
ATE345787T1 (de) 2006-12-15
EP1368014A1 (de) 2003-12-10
US6906107B2 (en) 2005-06-14
US20040132829A1 (en) 2004-07-08
DE60216239D1 (de) 2007-01-04
CA2438509C (en) 2010-04-20
EP1368014B1 (de) 2006-11-22
CA2438509A1 (en) 2002-08-29
WO2002066024A1 (en) 2002-08-29
DE60216239T2 (de) 2007-03-08

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Legal Events

Date Code Title Description
8381 Inventor (new situation)

Inventor name: MIYAGAWA, MASAO, 86,NISHI-CHO,YONAGO-SHI,TOTTO, JP

Inventor name: WATANABE, TAKESHI, 86,NISHI-CHO,YONAGO-SHI,TOT, JP

Inventor name: SAITO, MOTOAKI, 86,NISHI-CHO,YONAGO-SHI,TOTTOR, JP

Inventor name: LUU, BANG

Inventor name: YAMADA, M., TOKYO 136-8908, JP

Inventor name: SUZUKI, H., TOKYO 136-8908, JP

8364 No opposition during term of opposition
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