DE60208792D1 - Tyrosin-kinase inhibitoren - Google Patents
Tyrosin-kinase inhibitorenInfo
- Publication number
- DE60208792D1 DE60208792D1 DE60208792T DE60208792T DE60208792D1 DE 60208792 D1 DE60208792 D1 DE 60208792D1 DE 60208792 T DE60208792 T DE 60208792T DE 60208792 T DE60208792 T DE 60208792T DE 60208792 D1 DE60208792 D1 DE 60208792D1
- Authority
- DE
- Germany
- Prior art keywords
- tyrosine kinase
- compounds
- kinase inhibitors
- present
- atherosclerosis
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US30024501P | 2001-06-22 | 2001-06-22 | |
| US300245P | 2001-06-22 | ||
| PCT/US2002/021110 WO2003000687A1 (en) | 2001-06-22 | 2002-06-18 | Tyrosine kinase inhibitors |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE60208792D1 true DE60208792D1 (de) | 2006-04-06 |
| DE60208792T2 DE60208792T2 (de) | 2006-08-31 |
Family
ID=23158280
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60208792T Expired - Fee Related DE60208792T2 (de) | 2001-06-22 | 2002-06-18 | Tyrosin-kinase inhibitoren |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US6875767B2 (de) |
| EP (1) | EP1404672B1 (de) |
| JP (1) | JP2004535437A (de) |
| AT (1) | ATE316088T1 (de) |
| AU (1) | AU2002346053B2 (de) |
| CA (1) | CA2450562A1 (de) |
| DE (1) | DE60208792T2 (de) |
| ES (1) | ES2255621T3 (de) |
| WO (1) | WO2003000687A1 (de) |
Families Citing this family (67)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7265134B2 (en) | 2001-08-17 | 2007-09-04 | Merck & Co., Inc. | Tyrosine kinase inhibitors |
| AU2003241326B2 (en) | 2002-05-02 | 2008-05-01 | Merck & Co., Inc. | Tyrosine kinase inhibitors |
| JP2007530047A (ja) * | 2004-03-26 | 2007-11-01 | メルク エンド カムパニー インコーポレーテッド | 腫瘍内皮細胞の増殖を検出するための方法及びバイオマーカー |
| DK1756084T3 (da) * | 2004-06-04 | 2009-03-23 | Arena Pharm Inc | Substituerede aryl- og heteroarylderivater som modulatorer af metabolisme og forebyggelse og behandling af forstyrrelser beslægtet dermed |
| EP2277516A1 (de) | 2004-06-23 | 2011-01-26 | ReVision Therapeutics, Inc. | Retinyl-Derivate zur Behandlung von Augenleiden |
| EP1807103A4 (de) * | 2004-11-04 | 2009-02-11 | Sirion Therapeutics Inc | Modulatoren einer komplexen retinol-retinol-bindenden protein-transthyretin-formation |
| JP4178281B2 (ja) * | 2004-12-08 | 2008-11-12 | シリオン セラピューティクス， インコーポレイテッド | レチノール関連疾患を処置するための方法、アッセイおよび組成物 |
| WO2006129842A1 (ja) * | 2005-06-01 | 2006-12-07 | Banyu Pharmaceutical Co., Ltd. | オーロラa選択的阻害作用を有する新規アミノピリジン誘導体 |
| US8440217B1 (en) | 2005-06-15 | 2013-05-14 | Mawaheb M. EL-Naggar | Method and system with contact lens product for treating and preventing adverse eye conditions |
| UA81382C2 (en) * | 2005-07-11 | 2007-12-25 | Composition for treating retinol-related diseases by modulation of retinol binding | |
| ES2378704T3 (es) * | 2006-01-27 | 2012-04-17 | Array Biopharma, Inc. | Activadores de la glucocinasa |
| US8658633B2 (en) * | 2006-02-16 | 2014-02-25 | Massachusetts Eye And Ear Infirmary | Methods and compositions for treating conditions of the eye |
| US8296521B2 (en) * | 2006-06-30 | 2012-10-23 | Mosaid Technologies Incorporated | Method of configuring non-volatile memory for a hybrid disk drive |
| US8246966B2 (en) * | 2006-08-07 | 2012-08-21 | University Of Georgia Research Foundation, Inc. | Trypanosome microsome system and uses thereof |
| CA2669531A1 (en) | 2006-11-22 | 2008-06-05 | University Of Georgia Research Foundation, Inc. | Tyrosine kinase inhibitors as anti-kinetolastid and anti-apicomplexan agents |
| US8642067B2 (en) | 2007-04-02 | 2014-02-04 | Allergen, Inc. | Methods and compositions for intraocular administration to treat ocular conditions |
| CN101679406B (zh) * | 2007-04-10 | 2013-07-10 | 百时美施贵宝公司 | 用作激酶抑制剂的噻唑基化合物 |
| EP3078662A1 (de) * | 2007-09-21 | 2016-10-12 | Array Biopharma, Inc. | Pyridin-2-yl-amino-1,2,4-thiadiazol derivate als glucokinase aktivatoren zur behandlung von diabetes mellitus |
| DK2769737T3 (en) | 2009-07-20 | 2017-07-24 | Bristol Myers Squibb Co | COMBINATION OF ANTI-CTLA4 ANTIBODY WITH ETOPOSIDE FOR SYNERGISTIC TREATMENT OF PROLIFERATIVE DISEASES |
| CA2777934A1 (en) | 2009-10-20 | 2011-04-28 | Prometheus Laboratories Inc. | Proximity-mediated assays for detecting oncogenic fusion proteins |
| WO2012154257A1 (en) | 2011-02-17 | 2012-11-15 | Prometheus Laboratories Inc. | Apparatus and method for isolating leukocytes and tumor cells by filtration |
| PE20142406A1 (es) | 2012-05-04 | 2015-01-23 | Pfizer | Antigenos asociados a prostata y regimenes de inmunoterapia basados en vacuna |
| CN106211774B (zh) | 2013-08-02 | 2020-11-06 | 辉瑞公司 | 抗cxcr4抗体及抗体-药物缀合物 |
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| JP2018525029A (ja) | 2015-07-07 | 2018-09-06 | インセルム（インスティチュート ナショナル デ ラ サンテ エ デ ラ リシェルシェ メディカル） | ミオシン１８ａに対する特異性を有する抗体およびその使用 |
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| CN115160340B (zh) * | 2022-06-07 | 2023-07-21 | 四川大学华西医院 | 一种具有ack1抑制活性的小分子化合物及其应用 |
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| ID22273A (id) * | 1997-01-28 | 1999-09-23 | Merck & Co Inc | TIAZOL BENZENASULFONAMIDA SEBAGAI AGONIS β UNTUK PENGOBATAN DIABETES DAN OBESITAS |
| YU22400A (sh) * | 1997-10-27 | 2003-08-29 | Agouron Pharmaceuticals Inc. | Supstituisana 4-amino-tiazol-2-i jedinjenja kao cdks inhibitori |
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| ATE309241T1 (de) * | 1999-09-10 | 2005-11-15 | Merck & Co Inc | Tyrosin kinase inhibitoren |
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| US7555451B2 (en) * | 2001-05-17 | 2009-06-30 | Microsoft Corporation | Cash flow forecasting |
-
2002
- 2002-06-18 ES ES02744810T patent/ES2255621T3/es not_active Expired - Lifetime
- 2002-06-18 AT AT02744810T patent/ATE316088T1/de not_active IP Right Cessation
- 2002-06-18 WO PCT/US2002/021110 patent/WO2003000687A1/en active IP Right Grant
- 2002-06-18 CA CA002450562A patent/CA2450562A1/en not_active Abandoned
- 2002-06-18 JP JP2003507090A patent/JP2004535437A/ja active Pending
- 2002-06-18 EP EP02744810A patent/EP1404672B1/de not_active Expired - Lifetime
- 2002-06-18 DE DE60208792T patent/DE60208792T2/de not_active Expired - Fee Related
- 2002-06-18 AU AU2002346053A patent/AU2002346053B2/en not_active Ceased
- 2002-06-19 US US10/174,774 patent/US6875767B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US6875767B2 (en) | 2005-04-05 |
| EP1404672A1 (de) | 2004-04-07 |
| CA2450562A1 (en) | 2003-01-03 |
| JP2004535437A (ja) | 2004-11-25 |
| WO2003000687A1 (en) | 2003-01-03 |
| DE60208792T2 (de) | 2006-08-31 |
| ES2255621T3 (es) | 2006-07-01 |
| ATE316088T1 (de) | 2006-02-15 |
| AU2002346053B2 (en) | 2008-03-13 |
| US20030100567A1 (en) | 2003-05-29 |
| EP1404672B1 (de) | 2006-01-18 |
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| 8364 | No opposition during term of opposition | ||
| 8327 | Change in the person/name/address of the patent owner |
Owner name: MERCK & CO., INC., RAHWAY, N.J., US |
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| 8339 | Ceased/non-payment of the annual fee |