DE60207686D1 - Kombinationen von antiseptischen und antibiotischen mitteln enthaltende medizinische vorrichtungen - Google Patents

Kombinationen von antiseptischen und antibiotischen mitteln enthaltende medizinische vorrichtungen

Info

Publication number
DE60207686D1
DE60207686D1 DE60207686T DE60207686T DE60207686D1 DE 60207686 D1 DE60207686 D1 DE 60207686D1 DE 60207686 T DE60207686 T DE 60207686T DE 60207686 T DE60207686 T DE 60207686T DE 60207686 D1 DE60207686 D1 DE 60207686D1
Authority
DE
Germany
Prior art keywords
antiseptic
antibiotic
minocycline
combinations
bismuth salt
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60207686T
Other languages
English (en)
Inventor
M Modak
Suhas Tambe
A Sampath
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Columbia University in the City of New York
Original Assignee
Columbia University in the City of New York
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Columbia University in the City of New York filed Critical Columbia University in the City of New York
Application granted granted Critical
Publication of DE60207686D1 publication Critical patent/DE60207686D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L17/00—Materials for surgical sutures or for ligaturing blood vessels ; Materials for prostheses or catheters
    • A61L17/005—Materials for surgical sutures or for ligaturing blood vessels ; Materials for prostheses or catheters containing a biologically active substance, e.g. a medicament or a biocide
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N31/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic oxygen or sulfur compounds
    • A01N31/02—Acyclic compounds
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N59/00—Biocides, pest repellants or attractants, or plant growth regulators containing elements or inorganic compounds
    • A01N59/16—Heavy metals; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42—Use of materials characterised by their function or physical properties
    • A61L15/44—Medicaments
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
    • A61L29/14—Materials characterised by their function or physical properties, e.g. lubricating compositions
    • A61L29/16—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/10—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing inorganic materials
    • A61L2300/102—Metals or metal compounds, e.g. salts such as bicarbonates, carbonates, oxides, zeolites, silicates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/204—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials with nitrogen-containing functional groups, e.g. aminoxides, nitriles, guanidines
    • A61L2300/206—Biguanides, e.g. chlorohexidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
    • A61L2300/406—Antibiotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/45—Mixtures of two or more drugs, e.g. synergistic mixtures

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Materials Engineering (AREA)
  • Vascular Medicine (AREA)
  • Surgery (AREA)
  • Transplantation (AREA)
  • Wood Science & Technology (AREA)
  • Dermatology (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Agronomy & Crop Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Dentistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Materials For Medical Uses (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Apparatus For Disinfection Or Sterilisation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
DE60207686T 2001-02-02 2002-01-31 Kombinationen von antiseptischen und antibiotischen mitteln enthaltende medizinische vorrichtungen Expired - Lifetime DE60207686D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/775,775 US6582719B2 (en) 2001-02-02 2001-02-02 Combinations of antiseptic and antibiotic agents that inhibit the development of resistant microorganisms
PCT/US2002/003087 WO2003000303A1 (en) 2001-02-02 2002-01-31 Combinations of antiseptic and antibiotic agents containing medical devices

Publications (1)

Publication Number Publication Date
DE60207686D1 true DE60207686D1 (de) 2006-01-05

Family

ID=25105459

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60207686T Expired - Lifetime DE60207686D1 (de) 2001-02-02 2002-01-31 Kombinationen von antiseptischen und antibiotischen mitteln enthaltende medizinische vorrichtungen

Country Status (9)

Country Link
US (1) US6582719B2 (de)
EP (1) EP1363679B1 (de)
JP (1) JP2004533882A (de)
AT (1) ATE311209T1 (de)
CA (1) CA2437385A1 (de)
CZ (1) CZ20032075A3 (de)
DE (1) DE60207686D1 (de)
MX (1) MXPA03006618A (de)
WO (1) WO2003000303A1 (de)

Families Citing this family (48)

* Cited by examiner, † Cited by third party
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US6224579B1 (en) * 1999-03-31 2001-05-01 The Trustees Of Columbia University In The City Of New York Triclosan and silver compound containing medical devices
KR20020039689A (ko) * 1999-10-14 2002-05-27 토토라노 제이. 빈센트 정렬정보를 캐쉬하는 장치 및 방법
US7329412B2 (en) 2000-12-22 2008-02-12 The Trustees Of Columbia University In The City Of New York Antimicrobial medical devices containing chlorhexidine free base and salt
US20050192547A1 (en) * 2002-01-31 2005-09-01 Modak Shanta M. Combinations of antiseptic and antibiotic agents containing medical devices
EP1480517A4 (de) * 2002-02-07 2007-08-22 Univ Columbia Zinksalzzusammensetzungen für die vorbeugung von schleimhautreizung durch spermizide und mikrobizide
US7597903B2 (en) * 2002-12-02 2009-10-06 Shenkar College Of Engineering And Design Method and composition for producing catheters with antibacterial property
KR101106348B1 (ko) * 2003-05-23 2012-01-18 감브로 룬디아 아베 생적합성 중합체
SE526027C2 (sv) 2003-05-23 2005-06-14 Gambro Lundia Ab Biokompatibel polymerkomposition, förfarande för beredning av en biokompatibel sampolymerkomposition, artikel med en film av en polymerkomposition och användning av en biokompatibel polymerkomposition för en medicinsk anordning
US20050148553A1 (en) * 2003-09-05 2005-07-07 Testa Raymond T. Use of tigecycline, alone, or in combination with rifampin to treat osteomyelitis and/or septic arthritis
US7566502B1 (en) 2003-09-17 2009-07-28 Allegiance Corporation Surface modification of elastomeric articles
US8691258B2 (en) * 2003-12-12 2014-04-08 Medtronic, Inc. Anti-infective medical device
WO2005061003A1 (en) * 2003-12-12 2005-07-07 Medtronic, Inc. Anti-infective medical device
US20050186258A1 (en) * 2004-02-20 2005-08-25 Shiping Wang Antimicrobial medical gloves
GB0421164D0 (en) * 2004-09-23 2004-10-27 Univ Nottingham Medical devices and methods of making medical devices
EP1976388A1 (de) * 2005-04-08 2008-10-08 Ctt Group Inc. Metallsalz- und tensidhaltige antimikrobielle lösung
JP4999842B2 (ja) * 2005-07-01 2012-08-15 ケーン バイオテク インコーポレイテッド 医療用デバイス上における微生物バイオフィルムの生育および増殖を抑制するための抗菌性組成物
WO2007070795A2 (en) * 2005-12-12 2007-06-21 The Trustees Of Columbia University In The City Of New York Broad spectrum non-traditional preservative system
WO2008060380A2 (en) * 2006-10-18 2008-05-22 Arrow International, Inc. Anti-infective alcohol catheter solution with chlorhexidine treated catheter
US8343536B2 (en) 2007-01-25 2013-01-01 Cook Biotech Incorporated Biofilm-inhibiting medical products
US9687429B2 (en) * 2007-06-20 2017-06-27 The Trustees Of Columbia University In The City Of New York Antimicrobial compositions containing low concentrations of botanicals
EP2166840B1 (de) * 2007-06-20 2017-01-11 The Trustees of Columbia University in the City of New York Biofilmresistente oberflächen
US20090035228A1 (en) * 2007-08-02 2009-02-05 Shanta Modak Skin and surface disinfectant compositions containing botanicals
US9511040B2 (en) 2007-06-20 2016-12-06 The Trustees Of Columbia University In The City Of New York Skin and surface disinfectant compositions containing botanicals
US9981069B2 (en) 2007-06-20 2018-05-29 The Trustees Of Columbia University In The City Of New York Bio-film resistant surfaces
US9247973B2 (en) 2007-09-28 2016-02-02 DePuy Synthes Products, Inc. Anti-microbial implant
WO2009124386A1 (en) * 2008-04-07 2009-10-15 Interface Biologics Inc. Combination therapy for the treatment of bacterial infections
US20100172848A1 (en) * 2008-08-01 2010-07-08 The Trustees Of Columbia University In The City Of New York Skin and surface disinfectant compositions containing botanicals
US9763697B2 (en) 2008-12-16 2017-09-19 DePuy Synthes Products, Inc. Anti-infective spinal rod with surface features
EP2373270B8 (de) 2009-01-07 2023-04-12 entrotech life sciences, inc. Chlorhexidinhaltige antimikrobielle beschichtungen
CA2751386C (en) * 2009-02-03 2018-03-06 Microbion Corporation Bismuth-thiols as antiseptics for epithelial tissues, acute and chronic wounds, bacterial biofilms and other indications
US9408393B2 (en) 2010-02-03 2016-08-09 Microbion Corporation Bismuth-thiols as antiseptics for agricultural, industrial and other uses
US9028878B2 (en) 2009-02-03 2015-05-12 Microbion Corporation Bismuth-thiols as antiseptics for biomedical uses, including treatment of bacterial biofilms and other uses
JP2010187910A (ja) * 2009-02-18 2010-09-02 Nippon Sherwood Medical Industries Ltd 抗菌性医療用具およびその製造方法
US8426044B2 (en) * 2009-03-20 2013-04-23 Board Of Regents, The University Of Texas System Method for imparting antimicrobial activity to a medical device
KR101966867B1 (ko) * 2010-02-03 2019-04-08 마이크로비온 코포레이션 세균 균막의 치료 및 다른 용도를 포함하는, 생의학적 용도를 위한 방부제로서 비스무트-티올
US9913862B2 (en) 2011-10-26 2018-03-13 Trustees Of Boston University Methods of treating gram-negative microbial infections
AU2012332495B2 (en) 2011-11-03 2017-06-08 The Trustees Of Columbia University In The City Of New York Composition with sustained antimicrobial activity
US9968101B2 (en) 2011-11-03 2018-05-15 The Trustees Of Columbia University In The City Of New York Botanical antimicrobial compositions
TW201330856A (zh) 2011-12-06 2013-08-01 Univ Columbia 廣效性的天然防腐組成物
EP2950804B1 (de) 2013-01-30 2017-12-06 Univerzita Palackého v Olomouci Antibiotische zusammensetzung und deren verwendung
JP6594295B2 (ja) 2013-04-18 2019-10-23 ボード・オブ・リージエンツ，ザ・ユニバーシテイ・オブ・テキサス・システム 抗菌カテーテル
WO2015161302A1 (en) 2014-04-18 2015-10-22 Entrotech Life Sciences, Inc. Methods of processing chlorhexidine-containing polymerizable compositions and antimicrobial articles formed thereby
US9970303B2 (en) 2014-05-13 2018-05-15 Entrotech, Inc. Erosion protection sleeve
GB201614087D0 (en) * 2016-08-17 2016-09-28 Byotrol Plc Anti-microbial composition
WO2018070874A1 (en) * 2016-10-12 2018-04-19 Rijksuniversiteit Groningen Means and methods for reducing or avoiding antibiotic resistance and spread of virulence in human pathogens
BR112021001731A2 (pt) 2018-07-31 2021-04-27 Microbion Corporation composições de bismuto-tiol e métodos de uso
JP2021533194A (ja) 2018-07-31 2021-12-02 マイクロビオン コーポレーション ビスマス・チオール組成物及び創傷を治療する方法
CN115029752B (zh) * 2022-06-28 2023-07-18 郑州大学 一种适用于骨植入镁或镁合金的复合涂层的制备方法

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US4064238A (en) 1972-08-18 1977-12-20 Dominique Bocher Antibiotic composition containing an antibiotic and as a potentiating agent pyrrolidone carboxylic acid or derivative thereof
JP2733849B2 (ja) 1987-10-12 1998-03-30 ボロディー，ソーマス・ユリウス 胃腸障害治療のための改良された方法
US5165952A (en) * 1989-01-18 1992-11-24 Becton, Dickinson And Company Anti-infective and antithrombogenic medical articles and method for their preparation
US5217493A (en) * 1992-03-11 1993-06-08 Board Of Regents, The University Of Texas System Antibacterial coated medical implants
US5688516A (en) * 1992-11-12 1997-11-18 Board Of Regents, The University Of Texas System Non-glycopeptide antimicrobial agents in combination with an anticoagulant, an antithrombotic or a chelating agent, and their uses in, for example, the preparation of medical devices
US5624704A (en) * 1995-04-24 1997-04-29 Baylor College Of Medicine Antimicrobial impregnated catheters and other medical implants and method for impregnating catheters and other medical implants with an antimicrobial agent
US5928671A (en) 1995-04-25 1999-07-27 Winthrop University Hospital Method and composition for inhibiting bacteria
US5772640A (en) * 1996-01-05 1998-06-30 The Trustees Of Columbia University Of The City Of New York Triclosan-containing medical devices
JPH10328293A (ja) * 1997-06-04 1998-12-15 Unitika Ltd 医療用具及びその製造方法
US6224579B1 (en) 1999-03-31 2001-05-01 The Trustees Of Columbia University In The City Of New York Triclosan and silver compound containing medical devices

Also Published As

Publication number Publication date
CZ20032075A3 (cs) 2005-03-16
WO2003000303A1 (en) 2003-01-03
MXPA03006618A (es) 2003-10-15
US20020173775A1 (en) 2002-11-21
JP2004533882A (ja) 2004-11-11
US6582719B2 (en) 2003-06-24
EP1363679A1 (de) 2003-11-26
ATE311209T1 (de) 2005-12-15
CA2437385A1 (en) 2003-01-03
EP1363679B1 (de) 2005-11-30

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8332 No legal effect for de