DE602006007337D1 - Substituierte pyrrolopyridine, zusammensetzungen damit und verfahren zu ihrer herstellung und verwendung - Google Patents

Substituierte pyrrolopyridine, zusammensetzungen damit und verfahren zu ihrer herstellung und verwendung

Info

Publication number
DE602006007337D1
DE602006007337D1 DE602006007337T DE602006007337T DE602006007337D1 DE 602006007337 D1 DE602006007337 D1 DE 602006007337D1 DE 602006007337 T DE602006007337 T DE 602006007337T DE 602006007337 T DE602006007337 T DE 602006007337T DE 602006007337 D1 DE602006007337 D1 DE 602006007337D1
Authority
DE
Germany
Prior art keywords
preparation
compositions therefor
substituted pyrrolopyridines
pyrrolopyridines
substituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602006007337T
Other languages
English (en)
Inventor
Michel Tabart
Eric Bacque
Frank Halley
Baptiste Ronan
Pascal Desmazeau
Fabrice Viviani
Catherine Souaille
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharma SA
Original Assignee
Aventis Pharma SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma SA filed Critical Aventis Pharma SA
Publication of DE602006007337D1 publication Critical patent/DE602006007337D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DE602006007337T 2005-04-26 2006-04-26 Substituierte pyrrolopyridine, zusammensetzungen damit und verfahren zu ihrer herstellung und verwendung Active DE602006007337D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0504173A FR2884821B1 (fr) 2005-04-26 2005-04-26 Pyrrolopyridines substitues, compositions les contenant, procede de fabrication et utilisation
PCT/FR2006/000925 WO2006114520A2 (fr) 2005-04-26 2006-04-26 Pyrrolopyridines substitues, compositions les contenant, procede de fabrication et utilisation

Publications (1)

Publication Number Publication Date
DE602006007337D1 true DE602006007337D1 (de) 2009-07-30

Family

ID=35517344

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602006007337T Active DE602006007337D1 (de) 2005-04-26 2006-04-26 Substituierte pyrrolopyridine, zusammensetzungen damit und verfahren zu ihrer herstellung und verwendung

Country Status (33)

Country Link
US (1) US7947706B2 (de)
EP (1) EP1877409B1 (de)
JP (1) JP2008539211A (de)
KR (1) KR20080007229A (de)
CN (1) CN101166739A (de)
AR (1) AR061386A1 (de)
AT (1) ATE433976T1 (de)
AU (1) AU2006239105A1 (de)
BR (1) BRPI0613161A2 (de)
CA (1) CA2605744A1 (de)
CR (1) CR9463A (de)
CY (1) CY1109369T1 (de)
DE (1) DE602006007337D1 (de)
DK (1) DK1877409T3 (de)
DO (1) DOP2006000096A (de)
EA (1) EA012983B1 (de)
ES (1) ES2328629T3 (de)
FR (1) FR2884821B1 (de)
GT (1) GT200600174A (de)
HR (1) HRP20090494T1 (de)
IL (1) IL186523A0 (de)
MA (1) MA29480B1 (de)
MX (1) MX2007013084A (de)
NO (1) NO20075918L (de)
PA (1) PA8671301A1 (de)
PE (1) PE20071420A1 (de)
PL (1) PL1877409T3 (de)
PT (1) PT1877409E (de)
RS (1) RS51136B (de)
SI (1) SI1877409T1 (de)
TN (1) TNSN07360A1 (de)
TW (1) TW200718701A (de)
WO (1) WO2006114520A2 (de)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8119655B2 (en) 2005-10-07 2012-02-21 Takeda Pharmaceutical Company Limited Kinase inhibitors
US20100120717A1 (en) * 2006-10-09 2010-05-13 Brown Jason W Kinase inhibitors
EP2223925A1 (de) * 2006-10-09 2010-09-01 Takeda Pharmaceutical Company Limited Kinase-Inhibitoren
WO2008063888A2 (en) 2006-11-22 2008-05-29 Plexxikon, Inc. Compounds modulating c-fms and/or c-kit activity and uses therefor
MX2009006704A (es) 2006-12-22 2009-06-30 Astex Therapeutics Ltd Derivados de amina triciclicos como inhibidores de proteina de tirosina cinasa.
AR064491A1 (es) * 2006-12-22 2009-04-08 Astex Therapeutics Ltd Derivados de imidazo[1, 2-a]pirimidina, un proceso para su preparacion, una composicion farmaceutica que los comprende y su uso en el tratamiento de enfermedades mediadas por las quinasas fgfr.
CN101808994B (zh) 2007-07-17 2013-05-15 普莱希科公司 用于激酶调节的化合物和方法以及其适应症
GB0720038D0 (en) * 2007-10-12 2007-11-21 Astex Therapeutics Ltd New compounds
GB0720041D0 (en) 2007-10-12 2007-11-21 Astex Therapeutics Ltd New Compounds
GB0810902D0 (en) * 2008-06-13 2008-07-23 Astex Therapeutics Ltd New compounds
DE102008052943A1 (de) 2008-10-23 2010-04-29 Merck Patent Gmbh Azaindolderivate
MA33028B1 (fr) 2009-04-03 2012-02-01 Plexxikon Inc Compositions et utilisations associees
GB0906470D0 (en) 2009-04-15 2009-05-20 Astex Therapeutics Ltd New compounds
GB0906472D0 (en) 2009-04-15 2009-05-20 Astex Therapeutics Ltd New compounds
US20110030037A1 (en) * 2009-07-07 2011-02-03 Vadim Olshansky Zone migration in network access
US8329724B2 (en) 2009-08-03 2012-12-11 Hoffmann-La Roche Inc. Process for the manufacture of pharmaceutically active compounds
CN102695417A (zh) 2009-11-06 2012-09-26 普莱希科公司 用于激酶调节的化合物和方法及其适应症
BR112013020041B1 (pt) 2011-02-07 2021-11-23 Plexxikon, Inc Compostos e composições para a modulação de quinases e uso dos mesmos
AR085279A1 (es) 2011-02-21 2013-09-18 Plexxikon Inc Formas solidas de {3-[5-(4-cloro-fenil)-1h-pirrolo[2,3-b]piridina-3-carbonil]-2,4-difluor-fenil}-amida del acido propano-1-sulfonico
WO2013181075A1 (en) * 2012-05-29 2013-12-05 Merck Sharp & Dohme Corp. Isotopically labeled biaryl urea compounds
US9150570B2 (en) 2012-05-31 2015-10-06 Plexxikon Inc. Synthesis of heterocyclic compounds
US20140275082A1 (en) * 2013-03-14 2014-09-18 Abbvie Inc. Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases
GB201310464D0 (en) * 2013-06-12 2013-07-24 Lytix Biopharma As Compounds
GB201310460D0 (en) * 2013-06-12 2013-07-24 Lytix Biopharma As Compounds

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3254843B2 (ja) * 1993-08-09 2002-02-12 三菱ウェルファーマ株式会社 新規縮合ヘテロ環誘導体
US6335342B1 (en) * 2000-06-19 2002-01-01 Pharmacia & Upjohn S.P.A. Azaindole derivatives, process for their preparation, and their use as antitumor agents
GB0115109D0 (en) * 2001-06-21 2001-08-15 Aventis Pharma Ltd Chemical compounds
EP1425284A2 (de) * 2001-09-11 2004-06-09 Smithkline Beecham Corporation Furo- und thienopyrimidinderivate als angiogeneseinhibitoren
WO2003028724A1 (en) * 2001-10-04 2003-04-10 Smithkline Beecham Corporation Chk1 kinase inhibitors
US7129225B2 (en) * 2001-10-22 2006-10-31 The Research Foundation Of State University Of New York Protection against and treatment of hearing loss
DE60316542T2 (de) * 2002-03-28 2008-07-03 Eisai R&D Management Co., Ltd. 7-azaindole als inhibitoren c-jun n-terminaler kinasen zur behandlung neurodegenerativer störungen
FR2878849B1 (fr) * 2004-12-06 2008-09-12 Aventis Pharma Sa Indoles substitues, compositions les contenant, procede de fabrication et utilisation

Also Published As

Publication number Publication date
SI1877409T1 (sl) 2009-12-31
TW200718701A (en) 2007-05-16
PL1877409T3 (pl) 2009-12-31
CN101166739A (zh) 2008-04-23
DK1877409T3 (da) 2009-10-05
BRPI0613161A2 (pt) 2010-12-21
EA200702329A1 (ru) 2008-02-28
CY1109369T1 (el) 2014-07-02
ES2328629T3 (es) 2009-11-16
AU2006239105A1 (en) 2006-11-02
KR20080007229A (ko) 2008-01-17
TNSN07360A1 (en) 2008-12-31
FR2884821A1 (fr) 2006-10-27
EP1877409A2 (de) 2008-01-16
WO2006114520A3 (fr) 2007-03-01
HRP20090494T1 (hr) 2009-10-31
NO20075918L (no) 2007-11-19
CR9463A (es) 2008-02-21
AR061386A1 (es) 2008-08-27
MX2007013084A (es) 2008-01-11
RS51136B (sr) 2010-10-31
US20080139606A1 (en) 2008-06-12
PA8671301A1 (es) 2006-12-07
ATE433976T1 (de) 2009-07-15
MA29480B1 (fr) 2008-05-02
FR2884821B1 (fr) 2007-07-06
IL186523A0 (en) 2008-01-20
PT1877409E (pt) 2009-09-16
GT200600174A (es) 2006-12-26
PE20071420A1 (es) 2007-01-20
WO2006114520A2 (fr) 2006-11-02
CA2605744A1 (fr) 2006-11-02
DOP2006000096A (es) 2007-04-15
US7947706B2 (en) 2011-05-24
EA012983B1 (ru) 2010-02-26
EP1877409B1 (de) 2009-06-17
JP2008539211A (ja) 2008-11-13

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Legal Events

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