ATE424455T1 - Ligationsvermittelnde codierung von kleinen molekülen - Google Patents

Ligationsvermittelnde codierung von kleinen molekülen

Info

Publication number
ATE424455T1
ATE424455T1 AT04722237T AT04722237T ATE424455T1 AT E424455 T1 ATE424455 T1 AT E424455T1 AT 04722237 T AT04722237 T AT 04722237T AT 04722237 T AT04722237 T AT 04722237T AT E424455 T1 ATE424455 T1 AT E424455T1
Authority
AT
Austria
Prior art keywords
chemical entities
template
encoded molecule
codon
identifier polynucleotide
Prior art date
Application number
AT04722237T
Other languages
English (en)
Inventor
Thomas Franch
Soeren Jacobsen
Torben Rasmussen
Soeren Neve
Henrik Pedersen
Alex Gouliaev
Original Assignee
Nuevolution As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nuevolution As filed Critical Nuevolution As
Application granted granted Critical
Publication of ATE424455T1 publication Critical patent/ATE424455T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C07H21/04—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1068—Template (nucleic acid) mediated chemical library synthesis, e.g. chemical and enzymatical DNA-templated organic molecule synthesis, libraries prepared by non ribosomal polypeptide synthesis [NRPS], DNA/RNA-polymerase mediated polypeptide synthesis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00—Libraries per se, e.g. arrays, mixtures
    • C40B40/04—Libraries containing only organic compounds
    • C40B40/06—Libraries containing nucleotides or polynucleotides, or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B50/00—Methods of creating libraries, e.g. combinatorial synthesis
    • C40B50/04—Methods of creating libraries, e.g. combinatorial synthesis using dynamic combinatorial chemistry techniques

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
AT04722237T 2003-03-20 2004-03-22 Ligationsvermittelnde codierung von kleinen molekülen ATE424455T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US45585803P 2003-03-20 2003-03-20
DKPA200300430 2003-03-20

Publications (1)

Publication Number Publication Date
ATE424455T1 true ATE424455T1 (de) 2009-03-15

Family

ID=33031172

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04722237T ATE424455T1 (de) 2003-03-20 2004-03-22 Ligationsvermittelnde codierung von kleinen molekülen

Country Status (6)

Country Link
US (1) US7915201B2 (de)
EP (2) EP1608748B1 (de)
AT (1) ATE424455T1 (de)
DE (1) DE602004019764D1 (de)
DK (2) DK2236606T3 (de)
WO (1) WO2004083427A2 (de)

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DE602005012319D1 (de) 2004-11-22 2009-02-26 Peter Birk Rasmussen Matrizengerichtete split-and-mix-synthese von bibliotheken kleiner moleküle

Also Published As

Publication number Publication date
WO2004083427A2 (en) 2004-09-30
DK2236606T3 (da) 2014-02-10
EP2236606B1 (de) 2013-11-06
WO2004083427A3 (en) 2005-02-17
EP2236606A3 (de) 2010-10-20
DE602004019764D1 (de) 2009-04-16
US7915201B2 (en) 2011-03-29
EP1608748B1 (de) 2009-03-04
US20060246450A1 (en) 2006-11-02
EP1608748A2 (de) 2005-12-28
DK1608748T3 (da) 2009-06-29
EP2236606A2 (de) 2010-10-06

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