DE60138476D1 - Nateglinid enthaltende hydrophile arzneimittelpräparate - Google Patents

Nateglinid enthaltende hydrophile arzneimittelpräparate

Info

Publication number
DE60138476D1
DE60138476D1 DE60138476T DE60138476T DE60138476D1 DE 60138476 D1 DE60138476 D1 DE 60138476D1 DE 60138476 T DE60138476 T DE 60138476T DE 60138476 T DE60138476 T DE 60138476T DE 60138476 D1 DE60138476 D1 DE 60138476D1
Authority
DE
Germany
Prior art keywords
preparation
nateglinid
containing hydrophilic
hydrophilic drug
nateglinide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60138476T
Other languages
English (en)
Inventor
Nobutaka Ninomiya
Chisato Makino
Akira Yabuki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ajinomoto Co Inc
Original Assignee
Ajinomoto Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ajinomoto Co Inc filed Critical Ajinomoto Co Inc
Application granted granted Critical
Publication of DE60138476D1 publication Critical patent/DE60138476D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/2853—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers, poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Biophysics (AREA)
  • Organic Chemistry (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Non-Silver Salt Photosensitive Materials And Non-Silver Salt Photography (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE60138476T 2000-10-24 2001-10-23 Nateglinid enthaltende hydrophile arzneimittelpräparate Expired - Lifetime DE60138476D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2000324374 2000-10-24
PCT/JP2001/009292 WO2002040010A1 (fr) 2000-10-24 2001-10-23 Preparations de medicament contenant du nateglinide

Publications (1)

Publication Number Publication Date
DE60138476D1 true DE60138476D1 (de) 2009-06-04

Family

ID=18801919

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60138476T Expired - Lifetime DE60138476D1 (de) 2000-10-24 2001-10-23 Nateglinid enthaltende hydrophile arzneimittelpräparate

Country Status (19)

Country Link
US (1) US20040029968A1 (de)
EP (1) EP1334721B1 (de)
JP (3) JPWO2002040010A1 (de)
KR (1) KR100829410B1 (de)
CN (1) CN100531730C (de)
AT (1) ATE429217T1 (de)
AU (1) AU2001296000A1 (de)
BR (1) BR0114897A (de)
CA (1) CA2426764C (de)
CY (1) CY1110320T1 (de)
DE (1) DE60138476D1 (de)
DK (1) DK1334721T3 (de)
ES (1) ES2321911T3 (de)
MX (1) MXPA03003686A (de)
PT (1) PT1334721E (de)
RU (1) RU2283104C2 (de)
SI (1) SI1334721T1 (de)
TW (1) TWI289461B (de)
WO (1) WO2002040010A1 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20020063282A (ko) * 1999-12-28 2002-08-01 아지노모토 가부시키가이샤 경구 투여용 당뇨병 치료제
DE60135674D1 (de) * 2000-10-24 2008-10-16 Ajinomoto Kk Nateglinid enthaltende präparate
US6861553B2 (en) 2002-07-03 2005-03-01 Teva Pharmaceuticals Industries Ltd. Process for preparing nateglinide and intermediates thereof
US7148376B2 (en) 2002-07-18 2006-12-12 Teva Pharmaceutical Industries Ltd. Polymorphic forms of nateglinide
US7534913B2 (en) 2002-07-18 2009-05-19 Teva Pharmaceutica Industries Ltd. Crystalline form of nateglinide
US7420084B2 (en) 2002-07-18 2008-09-02 Teva Pharmaceutical Industries Ltd. Polymorphic forms of nateglinide
US7358390B2 (en) 2002-07-18 2008-04-15 Teva Pharmaceutical Industries Ltd. Polymorphic forms of nateglinide
KR20080083071A (ko) * 2003-08-08 2008-09-12 아지노모토 가부시키가이샤 나테글리니드 함유 제제
WO2005020979A1 (en) * 2003-09-03 2005-03-10 Ranbaxy Laboratories Limited A process for the preparation of pharmaceutical compositions of nateglinide
US20070219250A1 (en) * 2003-11-28 2007-09-20 Romi Singh Pharmaceutical Compositions of Nateglinide
WO2005092319A1 (en) * 2004-03-29 2005-10-06 Ranbaxy Laboratories Limited Rapidly disintegrating pharmaceutical compositions comprising nateglinide and a disintegrant
WO2005094812A1 (ja) * 2004-04-01 2005-10-13 Ajinomoto Co., Inc. ナテグリニド含有製剤
WO2009038770A2 (en) * 2007-09-20 2009-03-26 University Of Massachusetts Cvip Detoxified recombinant botulinum neurotoxin
WO2013066278A1 (en) * 2011-11-03 2013-05-10 Mahmut Bilgic A process for production of pharmaceutical formulations comprising nateglinide
WO2013115739A1 (en) * 2012-01-31 2013-08-08 Mahmut Bilgic Production method for formulations comprising comprising nateglinide and lipoic acid

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH066532B2 (ja) * 1983-09-29 1994-01-26 日産化学工業株式会社 親水性コロイドにより変性したワックス性微粉末
JPS6354321A (ja) * 1985-03-27 1988-03-08 Ajinomoto Co Inc 血糖降下剤
US5474989A (en) * 1988-11-11 1995-12-12 Kurita Water Industries, Ltd. Drug composition
ES2100291T3 (es) * 1991-07-30 1997-06-16 Ajinomoto Kk Cristales de n-(trans-4-isopropilciclohexilcarbonil)-d-fenilalanina y metodos para prepararlos.
US5463116A (en) * 1991-07-30 1995-10-31 Ajinomoto Co., Inc. Crystals of N- (trans-4-isopropylcyclohexlycarbonyl)-D-phenylalanine and methods for preparing them
JPH0696517B2 (ja) * 1993-03-17 1994-11-30 日産化学工業株式会社 変性したワックス性微粉末で被覆された薬剤及びその製造法
JP2994956B2 (ja) * 1994-05-31 1999-12-27 信越化学工業株式会社 低置換度ヒドロキシプロピルセルロース、その組成物およびその錠剤
PT965339E (pt) * 1996-11-15 2006-06-30 Ajinomoto Kk Composicao de nateglinida em comprimidos
CA2216215A1 (en) * 1997-04-05 1998-10-05 Isa Odidi Controlled release formulations using intelligent polymers having opposing wettability characteristics of hydrophobicity and hydrophilicity
JP3591801B2 (ja) * 1997-06-19 2004-11-24 田辺製薬株式会社 口腔内速崩壊性製剤の製法
JP2000178183A (ja) * 1998-12-17 2000-06-27 Lion Corp 固形製剤及びその製造方法
JP2000290171A (ja) * 1999-04-06 2000-10-17 Eisai Co Ltd 崩壊のはやい錠剤又はその製造方法
KR20020063282A (ko) * 1999-12-28 2002-08-01 아지노모토 가부시키가이샤 경구 투여용 당뇨병 치료제
RU2281764C2 (ru) * 2000-03-17 2006-08-20 Адзиномото Ко., Инк. Лекарственные средства для лечения осложнений, связанных с диабетом, и невропатии и их применения
ATE373635T1 (de) * 2000-10-18 2007-10-15 Ajinomoto Kk Verfahren zur herstellung von acylphenylalaninen
RU2273629C2 (ru) * 2000-10-18 2006-04-10 Адзиномото Ко., Инк. Способы получения кристаллов натеглинида
DE60135674D1 (de) * 2000-10-24 2008-10-16 Ajinomoto Kk Nateglinid enthaltende präparate
EP1334964B1 (de) * 2000-10-24 2007-08-15 Ajinomoto Co., Inc. Verfahren zur herstellung der b-form von nateglinid-kristallen
US6830759B2 (en) * 2002-06-28 2004-12-14 Ajinomoto Co., Inc. Antidiabetic preparation for oral administration

Also Published As

Publication number Publication date
WO2002040010A1 (fr) 2002-05-23
DK1334721T3 (da) 2009-07-06
CA2426764A1 (en) 2003-04-23
PT1334721E (pt) 2009-06-01
JPWO2002040010A1 (ja) 2004-06-03
KR20030042028A (ko) 2003-05-27
JP5673972B2 (ja) 2015-02-18
CY1110320T1 (el) 2015-01-14
JP5278708B2 (ja) 2013-09-04
KR100829410B1 (ko) 2008-05-15
JP2013064018A (ja) 2013-04-11
SI1334721T1 (sl) 2009-08-31
US20040029968A1 (en) 2004-02-12
CN100531730C (zh) 2009-08-26
CN1482904A (zh) 2004-03-17
JP2010095551A (ja) 2010-04-30
ATE429217T1 (de) 2009-05-15
CA2426764C (en) 2010-04-20
TWI289461B (en) 2007-11-11
EP1334721B1 (de) 2009-04-22
ES2321911T3 (es) 2009-06-15
EP1334721A4 (de) 2005-11-02
BR0114897A (pt) 2003-08-12
AU2001296000A1 (en) 2002-05-27
RU2283104C2 (ru) 2006-09-10
EP1334721A1 (de) 2003-08-13
MXPA03003686A (es) 2004-01-26

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Legal Events

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