DE60105113D1 - Verfahren zur Herstellung von einem Kristallepoxid - Google Patents

Verfahren zur Herstellung von einem Kristallepoxid

Info

Publication number
DE60105113D1
DE60105113D1 DE60105113T DE60105113T DE60105113D1 DE 60105113 D1 DE60105113 D1 DE 60105113D1 DE 60105113 T DE60105113 T DE 60105113T DE 60105113 T DE60105113 T DE 60105113T DE 60105113 D1 DE60105113 D1 DE 60105113D1
Authority
DE
Germany
Prior art keywords
epoxide compound
epoxy
production
phenylbutane
butoxycarbonylamino
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60105113T
Other languages
English (en)
Other versions
DE60105113T2 (de
Inventor
Yuichi Suzuki
Naoko Hirose
Tomoyuki Onishi
Kunisuke Izawa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ajinomoto Co Inc
Original Assignee
Ajinomoto Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ajinomoto Co Inc filed Critical Ajinomoto Co Inc
Publication of DE60105113D1 publication Critical patent/DE60105113D1/de
Application granted granted Critical
Publication of DE60105113T2 publication Critical patent/DE60105113T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/36—Compounds containing oxirane rings with hydrocarbon radicals, substituted by nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D301/00—Preparation of oxiranes
    • C07D301/36—Use of additives, e.g. for stabilisation

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Epoxy Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE60105113T 2000-12-12 2001-12-12 Verfahren zur Herstellung von einem Kristallepoxid Expired - Fee Related DE60105113T2 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP2000377804 2000-12-12
JP2000377804 2000-12-12
JP2001051108 2001-02-26
JP2001051108 2001-02-26

Publications (2)

Publication Number Publication Date
DE60105113D1 true DE60105113D1 (de) 2004-09-30
DE60105113T2 DE60105113T2 (de) 2005-08-18

Family

ID=26605686

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60105113T Expired - Fee Related DE60105113T2 (de) 2000-12-12 2001-12-12 Verfahren zur Herstellung von einem Kristallepoxid

Country Status (6)

Country Link
US (1) US6764545B2 (de)
EP (1) EP1215209B1 (de)
KR (1) KR20020046948A (de)
AT (1) ATE274504T1 (de)
CA (1) CA2364838A1 (de)
DE (1) DE60105113T2 (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7772411B2 (en) 2003-12-23 2010-08-10 Tibotec Pharmaceuticals Ltd. Process for the preparation of (3R,3aS,6aR)-hexahydrofuro [2,3-b] furan-3-yl (1S,2R)-3[[(4-aminophenyl) sulfonyl] (isobutyl) amino]-1-benzyl-2-hydroxypropylcarbamate
CN1898248B (zh) 2003-12-23 2011-08-17 泰博特克药品有限公司 制备(3r,3as,6ar)-六氢呋喃并[2,3-b]呋喃-3-基(1s,2r)-3-[[(4-氨基苯基)磺酰基](异丁基)氨基]-1-苄基-2-羟基丙基氨基甲酸酯的方法
WO2006126255A1 (ja) 2005-05-24 2006-11-30 Daito Chemix Corporation Ｎ－（２－ブロモエチル）カルバミン酸ｔｅｒｔ－ブチルの製造方法
US7582468B2 (en) * 2005-05-25 2009-09-01 Bristol-Myers Squibb Company Process for preparing (2R,3S)-1,2-epoxy-3-(protected)amino-4-substituted butane and intermediates thereof
JP2007112723A (ja) * 2005-10-18 2007-05-10 Ajinomoto Co Inc アミノクロロヒドリン硫酸塩の製造方法
US8153829B2 (en) 2006-11-09 2012-04-10 Janssen Pharmaceutica N.V. Methods for the preparation of hexahydrofuro[2,3-B]furan-3-ol
AU2008244306A1 (en) 2007-04-27 2008-11-06 Tibotec Pharmaceuticals Ltd. Methods for the preparation of N-isobutyl-N-(2-hydroxy-3-amino-4-phenylbutyl)-p-nitrobenzenesulfonylamide derivatives
JP2010530890A (ja) * 2007-06-22 2010-09-16 ブリストル−マイヤーズ スクイブ カンパニー アタザナビルを含む錠剤組成物
EP2178511B1 (de) * 2007-06-22 2011-03-02 Bristol-Myers Squibb Company Tablettierte atazanavirhaltige zusammensetzungen
AU2008268537B2 (en) * 2007-06-22 2012-11-01 Bristol-Myers Squibb Holdings Ireland Tableted compositions containing atazanavir
ES2449074T3 (es) * 2007-06-22 2014-03-18 Bristol-Myers Squibb Holdings Ireland Composiciones en forma de comprimidos que contienen atazanavir
EP2288593A1 (de) * 2008-05-08 2011-03-02 Ranbaxy Laboratories Limited Verfahren zur herstellung von 3,4-epoxy-2-amino-1-substituierten butanderivaten und zwischenprodukte dafür
KR100970596B1 (ko) * 2008-06-24 2010-07-16 대한주택공사 선상이동이 가능한 도어벽체 구조
AR073248A1 (es) 2008-09-01 2010-10-20 Tibotec Pharm Ltd Proceso para la preparacion de (1s, 2r)-3- ((4-aminofenil) sulfonil) ( isobutil) amino)-1- bencil-2- hidroxipropilcarbamato de (3r, 3as,6ar)- hexahidrofuro-(2,3-b) furan-3- ilo (darunavir) y compuestos intermediarios utiles en dicho proceso.
US8921415B2 (en) 2009-01-29 2014-12-30 Mapi Pharma Ltd. Polymorphs of darunavir
WO2011092687A1 (en) 2010-01-28 2011-08-04 Mapi Pharma Hk Limited Process for the preparation of darunavir and darunavir intermediates
CN103044361B (zh) * 2012-12-30 2014-08-06 江苏八巨药业有限公司 一种（2r,3s）-环氧化氨基苯丁烷的制备方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH515925A (de) * 1968-11-21 1971-11-30 Ciba Geigy Ag Verfahren zur Herstellung neuer B-Methylglycidyl-isocyanurate und ihre Verwendung zur Herstellung härtbarer Massen
US3676433A (en) * 1970-09-15 1972-07-11 Upjohn Co Improved process for the 5{60 ,6{60 -epoxidation of {66 {11 -double bonds
US5166371A (en) * 1989-07-31 1992-11-24 Arco Chemical Technology, L.P. Asymmetric epoxidation using a chiral hydroperoxide
US5559256A (en) 1992-07-20 1996-09-24 E. R. Squibb & Sons, Inc. Aminediol protease inhibitors
US5481011A (en) 1994-12-13 1996-01-02 Bristol-Myers Squibb Company Process for preparing N-protected amino acid α-halomethyl ketones and alcohols from N-protected amino acid esters
CA2186483A1 (en) * 1995-02-03 1996-08-08 Akira Nishiyama Processes for producing .alpha.-halo ketones, .alpha.-halohydrins and epoxides
HUP0101263A3 (en) 1998-01-28 2002-04-29 Nippon Kayaku Kk Process for producing optically active threo-3-amino-1,2-epoxy compounds
ATE334121T1 (de) 1999-01-29 2006-08-15 Kaneka Corp Verfahren zur herstellung von threo-1,2-epoxy-3- amino-4-phenylbutan-derivaten
KR100708221B1 (ko) 1999-08-31 2007-04-17 아지노모토 가부시키가이샤 에폭사이드 결정의 제조방법

Also Published As

Publication number Publication date
CA2364838A1 (en) 2002-06-12
EP1215209B1 (de) 2004-08-25
EP1215209A1 (de) 2002-06-19
DE60105113T2 (de) 2005-08-18
KR20020046948A (ko) 2002-06-21
ATE274504T1 (de) 2004-09-15
US20020087014A1 (en) 2002-07-04
US6764545B2 (en) 2004-07-20

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee