DE3768232D1 - Dimethyldioctadecylammoniumbromid enthaltende stabilisierte adjuvanssuspension. - Google Patents

Dimethyldioctadecylammoniumbromid enthaltende stabilisierte adjuvanssuspension.

Info

Publication number
DE3768232D1
DE3768232D1 DE8787202523T DE3768232T DE3768232D1 DE 3768232 D1 DE3768232 D1 DE 3768232D1 DE 8787202523 T DE8787202523 T DE 8787202523T DE 3768232 T DE3768232 T DE 3768232T DE 3768232 D1 DE3768232 D1 DE 3768232D1
Authority
DE
Germany
Prior art keywords
suspension
adjuvane
dimethyldioctadecylammonium bromide
containing stabilized
bromide containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8787202523T
Other languages
English (en)
Inventor
Lucas Alfonsus Theodor Hilgers
Marinus Wijnand Weststrate
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Duphar International Research BV
Original Assignee
Duphar International Research BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Duphar International Research BV filed Critical Duphar International Research BV
Application granted granted Critical
Publication of DE3768232D1 publication Critical patent/DE3768232D1/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Sorption Type Refrigeration Machines (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Liquid Crystal Substances (AREA)
  • Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)
  • Pyrrole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Materials Applied To Surfaces To Minimize Adherence Of Mist Or Water (AREA)
DE8787202523T 1986-12-19 1987-12-15 Dimethyldioctadecylammoniumbromid enthaltende stabilisierte adjuvanssuspension. Expired - Fee Related DE3768232D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NL8603232 1986-12-19

Publications (1)

Publication Number Publication Date
DE3768232D1 true DE3768232D1 (de) 1991-04-04

Family

ID=19849021

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8787202523T Expired - Fee Related DE3768232D1 (de) 1986-12-19 1987-12-15 Dimethyldioctadecylammoniumbromid enthaltende stabilisierte adjuvanssuspension.

Country Status (11)

Country Link
US (1) US5026546A (de)
EP (1) EP0273512B1 (de)
JP (1) JPS63165329A (de)
AT (1) ATE60999T1 (de)
DE (1) DE3768232D1 (de)
DK (1) DK661387A (de)
ES (1) ES2037072T3 (de)
GR (1) GR3001527T3 (de)
IE (1) IE60698B1 (de)
NZ (1) NZ222938A (de)
PT (1) PT86376B (de)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69001991T2 (de) * 1989-11-16 1993-09-23 Phidea Spa Fluessige arzneimittel zur nasalen anwendung, die ein polypeptid als wirksubstanz enthalten.
NZ239643A (en) * 1990-09-17 1996-05-28 North American Vaccine Inc Vaccine containing bacterial polysaccharide protein conjugate and adjuvant (c-nd-che-a-co-b-r) with a long chain alkyl group.
IL105325A (en) * 1992-04-16 1996-11-14 Minnesota Mining & Mfg Immunogen/vaccine adjuvant composition
US6991797B2 (en) * 1993-07-02 2006-01-31 Statens Serum Institut M. tuberculosis antigens
US5955077A (en) * 1993-07-02 1999-09-21 Statens Seruminstitut Tuberculosis vaccine
BE1008977A5 (fr) * 1994-12-27 1996-10-01 Solvay Adjuvants pour vaccins.
US6982085B2 (en) * 1997-04-02 2006-01-03 Statens Serum Institut TB diagnostic based on antigens from M. tuberculosis
US7037510B2 (en) 1997-04-18 2006-05-02 Statens Serum Institut Hybrids of M. tuberculosis antigens
US20040013685A1 (en) * 1997-11-10 2004-01-22 Peter Andersen Nucleic acid fragments and polypeptide fragments derived from M. tuberculosis
FR2814957B1 (fr) * 2000-10-06 2002-12-20 Aventis Pasteur Composition vaccinale et procede de stabilisation
KR20050062542A (ko) * 2002-08-26 2005-06-23 화이자 프로덕츠 인코포레이티드 소의 호흡기 및 생식기계 감염에 대한 백신
US6962608B1 (en) 2002-10-01 2005-11-08 The Regents Of The University Of California Regenerable antimicrobial polymers and fibers with oxygen bleaches
US8193185B2 (en) 2003-01-21 2012-06-05 Novartis Vaccines And Diagnostics, Inc. Use of tryptanthrin compounds for immune potentiation
CA2520124A1 (en) 2003-03-28 2004-10-14 Chiron Corporation Use of benzazole compounds for immunopotentiation
WO2006115509A2 (en) 2004-06-24 2006-11-02 Novartis Vaccines And Diagnostics Inc. Small molecule immunopotentiators and assays for their detection
JP2008504292A (ja) 2004-06-24 2008-02-14 ノバルティス ヴァクシンズ アンド ダイアグノスティクス， インコーポレイテッド 免疫増強用の化合物
US7749520B2 (en) * 2004-07-07 2010-07-06 Statens Serum Institut Compositions and methods for stabilizing lipid based adjuvant formulations using glycolipids
ITBO20050363A1 (it) * 2005-05-26 2006-11-27 Maccaferri Spa Off Elemento leggero di protezione filtro del tipo a materasso
ATE539079T1 (de) 2006-03-23 2012-01-15 Novartis Ag Imidazochinoxalinverbindungen als immunmodulatoren
EP2010530A2 (de) * 2006-03-23 2009-01-07 Novartis AG Herstellungsverfahren für imidazolhaltige verbindungen
ES2388556T3 (es) * 2006-03-23 2012-10-16 Novartis Ag Compuestos inmunopotenciadores
CL2008001806A1 (es) * 2007-06-20 2008-09-05 Wyeth Corp Composicion de vacuna en emulsion agua en aceite que comprende un antigeno y un adyuvante en la fase acuosa; y metodo de elaboracion.
CN104758929B (zh) 2008-06-27 2018-05-25 硕腾有限责任公司 新颖的佐剂组合物
PT2364314E (pt) 2008-12-09 2014-06-09 Gilead Sciences Inc Moduladores de recetores toll-like
CN109675026A (zh) 2013-09-19 2019-04-26 硕腾服务有限责任公司 油基佐剂
WO2016001907A1 (en) 2014-07-02 2016-01-07 Prendergast Patrick T Mogroside iv and mogroside v as agonist/stimulator/un-blocking agent for toll-like receptor 4 and adjuvant for use in human/animal vaccine and to stimulate immunity against disease agents.
CN115317600A (zh) 2015-01-16 2022-11-11 硕腾服务有限责任公司 ***疫苗
TW202015725A (zh) 2018-06-04 2020-05-01 美商亞博創新醫藥有限公司 Tlr7 肽結合物
MX2020014087A (es) 2018-07-02 2021-04-12 Ayuvis Res Inc Moléculas inmunomoduladoras pequeñas novedosas.

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3919411A (en) * 1972-01-31 1975-11-11 Bayvet Corp Injectable adjuvant and compositions including such adjuvant

Also Published As

Publication number Publication date
ATE60999T1 (de) 1991-03-15
IE873407L (en) 1988-06-19
DK661387A (da) 1988-06-20
PT86376B (pt) 1990-11-20
EP0273512A2 (de) 1988-07-06
US5026546A (en) 1991-06-25
JPS63165329A (ja) 1988-07-08
EP0273512A3 (en) 1988-07-27
ES2037072T3 (es) 1993-06-16
IE60698B1 (en) 1994-08-10
GR3001527T3 (en) 1992-11-23
DK661387D0 (da) 1987-12-16
PT86376A (en) 1988-01-01
EP0273512B1 (de) 1991-02-27
NZ222938A (en) 1990-11-27

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee