DE3560830D1 - Compounds having peripheral calcium antagonist, anticonvulsive and eumetabolic activity, processes for the preparation thereof and pharmaceutical compositions containing them - Google Patents
Compounds having peripheral calcium antagonist, anticonvulsive and eumetabolic activity, processes for the preparation thereof and pharmaceutical compositions containing themInfo
- Publication number
- DE3560830D1 DE3560830D1 DE8585100737T DE3560830T DE3560830D1 DE 3560830 D1 DE3560830 D1 DE 3560830D1 DE 8585100737 T DE8585100737 T DE 8585100737T DE 3560830 T DE3560830 T DE 3560830T DE 3560830 D1 DE3560830 D1 DE 3560830D1
- Authority
- DE
- Germany
- Prior art keywords
- processes
- preparation
- eumetabolic
- anticonvulsive
- activity
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
- C07D295/182—Radicals derived from carboxylic acids
- C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/096—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT8419372A IT1213131B (it) | 1984-02-02 | 1984-02-02 | Composto ad attivita' calcio antagonista periferica, anticonvulsivante ed eumetabolica cerebrale,metodo per la sua preparazione e composizioni farmaceutiche. |
Publications (1)
Publication Number | Publication Date |
---|---|
DE3560830D1 true DE3560830D1 (en) | 1987-12-03 |
Family
ID=11157131
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE198585100737T Pending DE152799T1 (de) | 1984-02-02 | 1985-01-25 | Verbindungen mit peripherischen kalzium-antagonisten antikonvulsiver und eumetabolischer wirkung, verfahren zur herstellung und diese enthaltende pharmazeutische zusammensetzungen. |
DE8585100737T Expired DE3560830D1 (en) | 1984-02-02 | 1985-01-25 | Compounds having peripheral calcium antagonist, anticonvulsive and eumetabolic activity, processes for the preparation thereof and pharmaceutical compositions containing them |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE198585100737T Pending DE152799T1 (de) | 1984-02-02 | 1985-01-25 | Verbindungen mit peripherischen kalzium-antagonisten antikonvulsiver und eumetabolischer wirkung, verfahren zur herstellung und diese enthaltende pharmazeutische zusammensetzungen. |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP0152799B1 (de) |
AT (1) | ATE30422T1 (de) |
DE (2) | DE152799T1 (de) |
ES (1) | ES540042A0 (de) |
IT (1) | IT1213131B (de) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS61161272A (ja) * | 1985-01-11 | 1986-07-21 | Kanebo Ltd | 新規なピペラジン誘導体および該化合物を有効成分とする医薬組成物 |
US4792553A (en) * | 1986-02-04 | 1988-12-20 | Terumo Kabushiki Kaisha | Diene derivatives and vasodilators containing the same |
US5428037A (en) * | 1993-04-09 | 1995-06-27 | Syntex Pharmaceuticals, Ltd. | Heterocyclic derivatives in the treatment of Ischaemia and related diseases |
JP3150155B2 (ja) * | 1993-12-08 | 2001-03-26 | アルコン ラボラトリーズ,インコーポレイテッド | 有力なカルシウム拮抗活性および酸化防止活性の両方を有する化合物および細胞保護剤としてのその使用 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IE33283B1 (en) * | 1968-07-02 | 1974-05-15 | Pharmaceutica J Nv | N-arallyl-n'-aralkyl piperazines and pharmaceutical compositions thereof |
BE790971A (fr) * | 1971-11-09 | 1973-05-07 | Janssen Pharmaceutica Nv | Metode ter voorkoming van patologische reakties die de funktie van het komplement vereisen |
-
1984
- 1984-02-02 IT IT8419372A patent/IT1213131B/it active
-
1985
- 1985-01-25 AT AT85100737T patent/ATE30422T1/de not_active IP Right Cessation
- 1985-01-25 DE DE198585100737T patent/DE152799T1/de active Pending
- 1985-01-25 DE DE8585100737T patent/DE3560830D1/de not_active Expired
- 1985-01-25 EP EP85100737A patent/EP0152799B1/de not_active Expired
- 1985-02-01 ES ES540042A patent/ES540042A0/es active Granted
Also Published As
Publication number | Publication date |
---|---|
IT8419372A0 (it) | 1984-02-02 |
ES8601176A1 (es) | 1985-11-01 |
ATE30422T1 (de) | 1987-11-15 |
ES540042A0 (es) | 1985-11-01 |
EP0152799B1 (de) | 1987-10-28 |
IT1213131B (it) | 1989-12-14 |
EP0152799A1 (de) | 1985-08-28 |
DE152799T1 (de) | 1986-01-02 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ZA8410103B (en) | New phenylacetic acid derivatives,pharmaceutical compositions containing these compounds and processes for preparing them | |
NZ214610A (en) | Piperazine derivatives and pharmaceutical compositions | |
HK24995A (en) | Metoprolol succinate and pharmaceutical composition containing it | |
AU580355B2 (en) | N-((4,6-dimethoxypyrimidin-2-YL)Aminocarbonyl)-3- trifluoromethylpridine-2-sulfonamide or salts thereof, herbicidal composition containing the same, and process for the production of the compound | |
ES8802386A1 (es) | Procedimiento para prepara (1,2,4)-triazolo (1,5-c)quinazolinas | |
ZA851552B (en) | Benzisoselenazolethiones,processes for their preparation and pharmaceutical products containing these compounds | |
ES2000368A6 (es) | Un procedimiento para preparar di-t-butilfenoles sustituidos | |
HUT38340A (en) | Process for producing benzyl-phtalazinone derivatives and pharmaceutical compositions containing them | |
HUT38097A (en) | Process for preparing substituted benzopyrans and pharmaceutical compositions containing them as active substances | |
IE852823L (en) | Medicaments containing spergualin | |
AU6602394A (en) | New alpha-amino acid compounds, a process for the preparation thereof and pharmaceutical compositions containing them | |
DE3560830D1 (en) | Compounds having peripheral calcium antagonist, anticonvulsive and eumetabolic activity, processes for the preparation thereof and pharmaceutical compositions containing them | |
TW339325B (en) | Novel azepane derivatives, process for the preparation thereof and pharmaceutical composition containing the same | |
GB2171095B (en) | Pharmaceutical substituted 2,5 dihydroxybenzene compounds | |
ES8604210A1 (es) | Procedimiento para preparar 2- (fenetil) -5- (3,4-metilen- dioxi)-x-hidroxibencil) -pirrolidina | |
AU556474B2 (en) | Benzhydryl piperazine derivatives | |
WO1987002666A3 (en) | Bicyclic alkoxy- and alkylthio-substituted aminoalcohols | |
AU572147B2 (en) | Dibenzopyran derivatives | |
TW265342B (de) | ||
PH20991A (en) | A piperazine derivatives, process for it's production and pharmaceutical composition containing the same | |
ES8600760A1 (es) | Procedimiento para preparar 2-((3, 4-metilendioxi)-fenetil)-5-((3-carboxamido-4-hidroxi)- -hidroxibencil)-pirrolidina | |
ZA853053B (en) | Pharmaceutical compositions of 4-(dibenzo-(a,d)cycloalkenyl)piperazine | |
EP0583561A3 (en) | Process for the preparation of 1-unsubstituted 3-aminopyrroles |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |