DE3560830D1 - Compounds having peripheral calcium antagonist, anticonvulsive and eumetabolic activity, processes for the preparation thereof and pharmaceutical compositions containing them - Google Patents

Compounds having peripheral calcium antagonist, anticonvulsive and eumetabolic activity, processes for the preparation thereof and pharmaceutical compositions containing them

Info

Publication number
DE3560830D1
DE3560830D1 DE8585100737T DE3560830T DE3560830D1 DE 3560830 D1 DE3560830 D1 DE 3560830D1 DE 8585100737 T DE8585100737 T DE 8585100737T DE 3560830 T DE3560830 T DE 3560830T DE 3560830 D1 DE3560830 D1 DE 3560830D1
Authority
DE
Germany
Prior art keywords
processes
preparation
eumetabolic
anticonvulsive
activity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8585100737T
Other languages
English (en)
Inventor
Giuseppe Quadro
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
PULITZER ITALIANA
Original Assignee
PULITZER ITALIANA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by PULITZER ITALIANA filed Critical PULITZER ITALIANA
Application granted granted Critical
Publication of DE3560830D1 publication Critical patent/DE3560830D1/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/096—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicinal Preparation (AREA)
DE8585100737T 1984-02-02 1985-01-25 Compounds having peripheral calcium antagonist, anticonvulsive and eumetabolic activity, processes for the preparation thereof and pharmaceutical compositions containing them Expired DE3560830D1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8419372A IT1213131B (it) 1984-02-02 1984-02-02 Composto ad attivita' calcio antagonista periferica, anticonvulsivante ed eumetabolica cerebrale,metodo per la sua preparazione e composizioni farmaceutiche.

Publications (1)

Publication Number Publication Date
DE3560830D1 true DE3560830D1 (en) 1987-12-03

Family

ID=11157131

Family Applications (2)

Application Number Title Priority Date Filing Date
DE198585100737T Pending DE152799T1 (de) 1984-02-02 1985-01-25 Verbindungen mit peripherischen kalzium-antagonisten antikonvulsiver und eumetabolischer wirkung, verfahren zur herstellung und diese enthaltende pharmazeutische zusammensetzungen.
DE8585100737T Expired DE3560830D1 (en) 1984-02-02 1985-01-25 Compounds having peripheral calcium antagonist, anticonvulsive and eumetabolic activity, processes for the preparation thereof and pharmaceutical compositions containing them

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE198585100737T Pending DE152799T1 (de) 1984-02-02 1985-01-25 Verbindungen mit peripherischen kalzium-antagonisten antikonvulsiver und eumetabolischer wirkung, verfahren zur herstellung und diese enthaltende pharmazeutische zusammensetzungen.

Country Status (5)

Country Link
EP (1) EP0152799B1 (de)
AT (1) ATE30422T1 (de)
DE (2) DE152799T1 (de)
ES (1) ES540042A0 (de)
IT (1) IT1213131B (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61161272A (ja) * 1985-01-11 1986-07-21 Kanebo Ltd 新規なピペラジン誘導体および該化合物を有効成分とする医薬組成物
US4792553A (en) * 1986-02-04 1988-12-20 Terumo Kabushiki Kaisha Diene derivatives and vasodilators containing the same
US5428037A (en) * 1993-04-09 1995-06-27 Syntex Pharmaceuticals, Ltd. Heterocyclic derivatives in the treatment of Ischaemia and related diseases
JP3150155B2 (ja) * 1993-12-08 2001-03-26 アルコン ラボラトリーズ，インコーポレイテッド 有力なカルシウム拮抗活性および酸化防止活性の両方を有する化合物および細胞保護剤としてのその使用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE33283B1 (en) * 1968-07-02 1974-05-15 Pharmaceutica J Nv N-arallyl-n'-aralkyl piperazines and pharmaceutical compositions thereof
BE790971A (fr) * 1971-11-09 1973-05-07 Janssen Pharmaceutica Nv Metode ter voorkoming van patologische reakties die de funktie van het komplement vereisen

Also Published As

Publication number Publication date
IT8419372A0 (it) 1984-02-02
ES8601176A1 (es) 1985-11-01
ATE30422T1 (de) 1987-11-15
ES540042A0 (es) 1985-11-01
EP0152799B1 (de) 1987-10-28
IT1213131B (it) 1989-12-14
EP0152799A1 (de) 1985-08-28
DE152799T1 (de) 1986-01-02

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee