DE3267110D1 - Amidine derivatives - Google Patents
Amidine derivativesInfo
- Publication number
- DE3267110D1 DE3267110D1 DE8282302092T DE3267110T DE3267110D1 DE 3267110 D1 DE3267110 D1 DE 3267110D1 DE 8282302092 T DE8282302092 T DE 8282302092T DE 3267110 T DE3267110 T DE 3267110T DE 3267110 D1 DE3267110 D1 DE 3267110D1
- Authority
- DE
- Germany
- Prior art keywords
- amidine derivatives
- amidine
- derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/42—One nitrogen atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/47—One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/04—1,2,3-Triazoles; Hydrogenated 1,2,3-triazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB8115156 | 1981-05-18 |
Publications (1)
Publication Number | Publication Date |
---|---|
DE3267110D1 true DE3267110D1 (de) | 1985-12-05 |
Family
ID=10521868
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE8282302092T Expired DE3267110D1 (de) | 1981-05-18 | 1982-04-23 | Amidine derivatives |
Country Status (4)
Country | Link |
---|---|
US (1) | US4748165A (de) |
EP (1) | EP0067508B1 (de) |
JP (1) | JPS57206664A (de) |
DE (1) | DE3267110D1 (de) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DZ3415A1 (fr) * | 2000-08-31 | 2002-03-07 | Chiron Corp | Guanidinobenzamides comme mc4-r agonistes. |
PT1385823E (pt) * | 2001-04-09 | 2007-01-31 | Novartis Vaccines & Diagnostic | Compostos de guanidino como agonistas do receptor de melanocortina-4 (r-mc4) |
US20070004743A1 (en) * | 2002-02-25 | 2007-01-04 | Xiao Linda L | Intranasal administration of mc4-r agonists |
AU2003245325A1 (en) * | 2002-05-23 | 2003-12-12 | Chiron Corporation | Substituted quinazolinone compounds |
WO2004112793A1 (en) * | 2003-05-23 | 2004-12-29 | Chiron Corporation | Guanidino-substituted quinazolinone compounds as mc4-r agonists |
CA2545601A1 (en) * | 2003-11-19 | 2005-06-09 | Chiron Corporation | Quinazolinone compounds with reduced bioaccumulation |
EP2822931B1 (de) | 2012-03-09 | 2017-05-03 | Inception 2, Inc. | Triazolonverbindungen und verwendungen davon |
SG11201504622PA (en) | 2012-12-20 | 2015-07-30 | Inception 2 Inc | Triazolone compounds and uses thereof |
CN105579440A (zh) | 2013-09-06 | 2016-05-11 | 因森普深2公司 | ***酮化合物及其应用 |
WO2022034121A1 (en) | 2020-08-11 | 2022-02-17 | Université De Strasbourg | H2 blockers targeting liver macrophages for the prevention and treatment of liver disease and cancer |
Family Cites Families (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GR62452B (en) * | 1977-04-20 | 1979-04-12 | Ici Ltd | Preparation process of guanidine derivatives |
US4165378A (en) * | 1977-04-20 | 1979-08-21 | Ici Americas Inc. | Guanidine derivatives of imidazoles and thiazoles |
BE866155A (fr) * | 1977-04-20 | 1978-10-19 | Ici Ltd | Nouveaux derives de la guanidine |
JPS5444660A (en) * | 1977-08-29 | 1979-04-09 | Yamanouchi Pharmaceut Co Ltd | Heterocyclic compound and its preparation |
DE2835695A1 (de) * | 1977-08-29 | 1979-03-15 | Yamanouchi Pharma Co Ltd | Neue heterocyclische verbindungen, verfahren zu ihrer herstellung und arzneimittel, die diese enthalten |
DE2963363D1 (en) * | 1978-05-24 | 1982-09-09 | Ici Plc | Antisecretory thiadiazole derivatives, processes for their manufacture and pharmaceutical compositions containing them |
JPS55115877A (en) * | 1979-02-28 | 1980-09-06 | Yamanouchi Pharmaceut Co Ltd | Novel amidine compound and its preparation |
JPS55115860A (en) * | 1979-03-02 | 1980-09-06 | Yamanouchi Pharmaceut Co Ltd | Novel amidine derivative and its preparation |
JPS6056143B2 (ja) * | 1979-08-02 | 1985-12-09 | 山之内製薬株式会社 | アミジン誘導体ならびにその製造法 |
PH16099A (en) * | 1979-03-06 | 1983-06-24 | Yamanouchi Pharma Co Ltd | Guanidinothiazole compounds,process for preparing them and medical composition containing them |
US4242351A (en) * | 1979-05-07 | 1980-12-30 | Imperial Chemical Industries Limited | Antisecretory oxadiazoles and pharmaceutical compositions containing them |
JPS5655383A (en) * | 1979-10-12 | 1981-05-15 | Yamanouchi Pharmaceut Co Ltd | Amizine derivative and its preparation |
GR71929B (de) * | 1979-11-13 | 1983-08-19 | Ici Ltd | |
FI73423C (fi) * | 1980-02-29 | 1987-10-09 | Otsuka Pharma Co Ltd | Foerfarande foer framstaellning av farmakologiskt verksamma tetrazolderivat. |
JPS56122368A (en) * | 1980-02-29 | 1981-09-25 | Yamanouchi Pharmaceut Co Ltd | Guanidinothiazole compound and its preparation |
JPS5726674A (en) * | 1980-07-22 | 1982-02-12 | Yamanouchi Pharmaceut Co Ltd | Novel amidine derivative and its preparation |
JPS5726663A (en) * | 1980-07-22 | 1982-02-12 | Yamanouchi Pharmaceut Co Ltd | Novel amidine derivative and its preparation |
JPS5726675A (en) * | 1980-07-23 | 1982-02-12 | Yamanouchi Pharmaceut Co Ltd | Novel guanidinothiazole derivative and its preparation |
GB2085871B (en) * | 1980-08-08 | 1984-07-25 | Kotobuki Seiyaku Co Ltd | New 3-substituted-2-propenimidamides and method of manufacturing the same |
ZA815961B (en) * | 1980-08-27 | 1983-04-27 | Glaxo Group Ltd | Heterocyclic derivatives |
-
1982
- 1982-04-23 EP EP82302092A patent/EP0067508B1/de not_active Expired
- 1982-04-23 DE DE8282302092T patent/DE3267110D1/de not_active Expired
- 1982-05-11 US US06/377,137 patent/US4748165A/en not_active Expired - Fee Related
- 1982-05-18 JP JP57083901A patent/JPS57206664A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
EP0067508A1 (de) | 1982-12-22 |
JPS57206664A (en) | 1982-12-18 |
EP0067508B1 (de) | 1985-10-30 |
US4748165A (en) | 1988-05-31 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |