JPS57206664A - Guanidine derivative, manufacture and histamine h-2-antagonistic and gastric acid secretion inhibiting pharmaceutical composition containing same - Google Patents

Guanidine derivative, manufacture and histamine h-2-antagonistic and gastric acid secretion inhibiting pharmaceutical composition containing same

Info

Publication number
JPS57206664A
JPS57206664A JP57083901A JP8390182A JPS57206664A JP S57206664 A JPS57206664 A JP S57206664A JP 57083901 A JP57083901 A JP 57083901A JP 8390182 A JP8390182 A JP 8390182A JP S57206664 A JPS57206664 A JP S57206664A
Authority
JP
Japan
Prior art keywords
histamine
antagonistic
manufacture
pharmaceutical composition
composition containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP57083901A
Other languages
English (en)
Inventor
Fureeto Jiyonzu Deriku
Oorudohamu Keito
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Imperial Chemical Industries Ltd
Original Assignee
Imperial Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Imperial Chemical Industries Ltd filed Critical Imperial Chemical Industries Ltd
Publication of JPS57206664A publication Critical patent/JPS57206664A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C07D239/42—One nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/47—One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/04—1,2,3-Triazoles; Hydrogenated 1,2,3-triazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
JP57083901A 1981-05-18 1982-05-18 Guanidine derivative, manufacture and histamine h-2-antagonistic and gastric acid secretion inhibiting pharmaceutical composition containing same Pending JPS57206664A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8115156 1981-05-18

Publications (1)

Publication Number Publication Date
JPS57206664A true JPS57206664A (en) 1982-12-18

Family

ID=10521868

Family Applications (1)

Application Number Title Priority Date Filing Date
JP57083901A Pending JPS57206664A (en) 1981-05-18 1982-05-18 Guanidine derivative, manufacture and histamine h-2-antagonistic and gastric acid secretion inhibiting pharmaceutical composition containing same

Country Status (4)

Country Link
US (1) US4748165A (ja)
EP (1) EP0067508B1 (ja)
JP (1) JPS57206664A (ja)
DE (1) DE3267110D1 (ja)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DZ3415A1 (fr) * 2000-08-31 2002-03-07 Chiron Corp Guanidinobenzamides comme mc4-r agonistes.
US7456183B2 (en) * 2001-04-09 2008-11-25 Novartis Vaccines And Diagnostics, Inc. Guanidino compounds
AU2003219914A1 (en) * 2002-02-25 2003-09-09 Chiron Corporation Intranasal administration of mc4-r agonists
AU2003245325A1 (en) 2002-05-23 2003-12-12 Chiron Corporation Substituted quinazolinone compounds
JP2007501861A (ja) * 2003-05-23 2007-02-01 カイロン コーポレイション Ｍｃ４−ｒアゴニストとしてのグアニジノ置換キナゾリノン化合物
WO2005051391A1 (en) * 2003-11-19 2005-06-09 Chiron Corporation Quinazolinone compounds with reduced bioaccumulation
US9505728B2 (en) 2012-03-09 2016-11-29 Inception 2, Inc. Triazolone compounds and uses thereof
CN104918922B (zh) 2012-12-20 2017-04-26 因森普深2公司 ***酮化合物及其用途
JP2016529311A (ja) 2013-09-06 2016-09-23 インセプション ２、 インコーポレイテッド トリアゾロン化合物類及びそれらの使用
US20230349922A1 (en) 2020-08-11 2023-11-02 Université De Strasbourg H2 Blockers Targeting Liver Macrophages for the Prevention and Treatment of Liver Disease and Cancer

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE866155A (fr) * 1977-04-20 1978-10-19 Ici Ltd Nouveaux derives de la guanidine
US4165378A (en) * 1977-04-20 1979-08-21 Ici Americas Inc. Guanidine derivatives of imidazoles and thiazoles
ZA782129B (en) * 1977-04-20 1979-03-28 Ici Ltd Hertocyclic derivatives
DE2835695A1 (de) * 1977-08-29 1979-03-15 Yamanouchi Pharma Co Ltd Neue heterocyclische verbindungen, verfahren zu ihrer herstellung und arzneimittel, die diese enthalten
JPS5444660A (en) * 1977-08-29 1979-04-09 Yamanouchi Pharmaceut Co Ltd Heterocyclic compound and its preparation
DE2963363D1 (en) * 1978-05-24 1982-09-09 Ici Plc Antisecretory thiadiazole derivatives, processes for their manufacture and pharmaceutical compositions containing them
JPS55115877A (en) * 1979-02-28 1980-09-06 Yamanouchi Pharmaceut Co Ltd Novel amidine compound and its preparation
JPS55115860A (en) * 1979-03-02 1980-09-06 Yamanouchi Pharmaceut Co Ltd Novel amidine derivative and its preparation
JPS6056143B2 (ja) * 1979-08-02 1985-12-09 山之内製薬株式会社 アミジン誘導体ならびにその製造法
PH16099A (en) * 1979-03-06 1983-06-24 Yamanouchi Pharma Co Ltd Guanidinothiazole compounds,process for preparing them and medical composition containing them
US4242351A (en) * 1979-05-07 1980-12-30 Imperial Chemical Industries Limited Antisecretory oxadiazoles and pharmaceutical compositions containing them
JPS5655383A (en) * 1979-10-12 1981-05-15 Yamanouchi Pharmaceut Co Ltd Amizine derivative and its preparation
GR71929B (ja) * 1979-11-13 1983-08-19 Ici Ltd
FI73423C (fi) * 1980-02-29 1987-10-09 Otsuka Pharma Co Ltd Foerfarande foer framstaellning av farmakologiskt verksamma tetrazolderivat.
JPS56122368A (en) * 1980-02-29 1981-09-25 Yamanouchi Pharmaceut Co Ltd Guanidinothiazole compound and its preparation
JPS5726674A (en) * 1980-07-22 1982-02-12 Yamanouchi Pharmaceut Co Ltd Novel amidine derivative and its preparation
JPS5726663A (en) * 1980-07-22 1982-02-12 Yamanouchi Pharmaceut Co Ltd Novel amidine derivative and its preparation
JPS5726675A (en) * 1980-07-23 1982-02-12 Yamanouchi Pharmaceut Co Ltd Novel guanidinothiazole derivative and its preparation
GB2085871B (en) * 1980-08-08 1984-07-25 Kotobuki Seiyaku Co Ltd New 3-substituted-2-propenimidamides and method of manufacturing the same
JPS5775975A (en) * 1980-08-27 1982-05-12 Glaxo Group Ltd Heterocyclic derivative, manufacture and medicinal composition containing same

Also Published As

Publication number Publication date
EP0067508B1 (en) 1985-10-30
DE3267110D1 (de) 1985-12-05
US4748165A (en) 1988-05-31
EP0067508A1 (en) 1982-12-22

Similar Documents

Publication Publication Date Title
IL66501A (en) Benzazepine-2-one derivatives,their manufacture and pharmaceutical compositions containing them
IL68618A0 (en) Heterocyclic compounds,their manufacture and pharmaceutical compositions containing them
IL65056A0 (en) Imidazodiazepines,their manufacture and pharmaceutical compositions containing them
JPS57159772A (en) 3,4-dihydro-5h-2,3-benzodiazepine derivatives, acid addition salts, manufacture and medicinal composition containing them
IL68323A0 (en) Phenoxyalkylcarboxylic acid derivatives,their manufacture and pharmaceutical compositions containing them
JPS57206664A (en) Guanidine derivative, manufacture and histamine h-2-antagonistic and gastric acid secretion inhibiting pharmaceutical composition containing same
IL65285A (en) 2-substituted-4,5-diarylthiazoles,their manufacture and pharmaceutical compositions containing them
IL65160A (en) Substituted heteroaromatic guanidine derivatives,their preparation and pharmaceutical compositions containing them
IL67284A (en) N-substituted-2-pyridylindoles,their manufacture and pharmaceutical compositions containing them
IL71711A0 (en) Pyrimidone derivatives,their manufacture and pharmaceutical compositions containing them
DE3265871D1 (en) 3-amino-2-hydroxy-4-phenylbutanoic acid derivatives and pharmaceutical composition containing the same
IL64880A0 (en) Imidazoline derivatives,processes for the preparation thereof and pharmaceutical compositions containing them
JPS57165373A (en) Guanidine derivative, manufacture and medicinal composition containing same for gastric acid secretion inhibition
IL72411A (en) ((pyridinyl)-2-pyrimidinyl)ureas,their preparation and pharmaceutical compositions containing them
HK86292A (en) Dihydroorotic acid derivatives,processes for their prepararing and pharmaceutical composition containing them
JPS57203064A (en) Amide derivative, manufacture and pharmaceutical composition containing same and having gastric acid secretion control activity
ZA825275B (en) Benzotriazoles,processes for their preparation,and pharmaceutical compositions thereof
JPS57171980A (en) Guanidine derivative, manufacture and gastric acid secretion inhibitor containing same
IL62509A (en) Monohydrated n,n'-bis-(3-picolyl)-4-methoxy-isophthalamide,its preparation and pharmaceutical compositions containing it
ZA824437B (en) Substituted pyrimidines,processes for their preparation and pharmaceutical compositions thereof
JPS57167969A (en) Guanidine derivative, manufacture and pharmaceutical composition containing same and having gastric acid secretion control
JPS57159769A (en) Guanidine derivative, manufacture and pharmaceutical composition containing same for gastric secretion inhibition
IL70992A0 (en) Hydantoin derivatives,their preparation and pharmaceutical compositions containing them
IL65876A0 (en) Heterocyclic amidoxime derivatives,their preparation and pharmaceutical compositions containing them
GB2109377B (en) Uracil derivatives, process for their preparation, and medicinal composition containing same