DE2305092A1 - Alpha-aminomethylbenzylalkoholderivate - Google Patents
Alpha-aminomethylbenzylalkoholderivateInfo
- Publication number
- DE2305092A1 DE2305092A1 DE19732305092 DE2305092A DE2305092A1 DE 2305092 A1 DE2305092 A1 DE 2305092A1 DE 19732305092 DE19732305092 DE 19732305092 DE 2305092 A DE2305092 A DE 2305092A DE 2305092 A1 DE2305092 A1 DE 2305092A1
- Authority
- DE
- Germany
- Prior art keywords
- group
- benzyl
- alcohol
- added
- methyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/205—Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
- C07C215/74—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton
- C07C215/76—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton of the same non-condensed six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/16—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP1312172A JPS5653537B2 (hu) | 1972-02-05 | 1972-02-05 | |
JP3941672A JPS49237A (hu) | 1972-04-19 | 1972-04-19 | |
JP5101372A JPS495934A (hu) | 1972-05-23 | 1972-05-23 | |
JP5291572 | 1972-05-27 |
Publications (2)
Publication Number | Publication Date |
---|---|
DE2305092A1 true DE2305092A1 (de) | 1973-08-16 |
DE2305092C2 DE2305092C2 (hu) | 1987-10-01 |
Family
ID=27455936
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE19732366625 Expired DE2366625C2 (hu) | 1972-02-05 | 1973-02-02 | |
DE19732305092 Granted DE2305092A1 (de) | 1972-02-05 | 1973-02-02 | Alpha-aminomethylbenzylalkoholderivate |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE19732366625 Expired DE2366625C2 (hu) | 1972-02-05 | 1973-02-02 |
Country Status (1)
Country | Link |
---|---|
DE (2) | DE2366625C2 (hu) |
Cited By (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4072760A (en) * | 1974-11-20 | 1978-02-07 | Pharmacia As | Bronchospasmolytic phenylethanolamines |
EP0068669A1 (en) * | 1981-06-20 | 1983-01-05 | Beecham Group Plc | Secondary phenylethanol amines, processes for their preparation and their pharmaceutical application |
EP0180994A2 (en) * | 1984-11-08 | 1986-05-14 | Syntex (U.S.A.) Inc. | Antihypertensive dialkyl aminoethylaniline derivatives |
US4975466A (en) * | 1986-06-05 | 1990-12-04 | Ciba-Geigy Corporation | Pharmaceutical preparations for topical application and their use in the treatment of inflammatory skin diseases |
EP0586344A1 (de) * | 1992-09-02 | 1994-03-09 | Ciba-Geigy Ag | Oxazolidin Verbindungen und ihre Verwendung als Arzneimittel |
LT3813B (en) | 1990-09-26 | 1996-03-25 | Astra Ab | Process for preparing 3-formamido-4-hydroxy-alpha£n£1-methyl-2(p-methoxyphenyl)ethylaminomethyl|benzyl alkohol fumarate (formoterol) and related compounds and derivatives thereof |
US6541669B1 (en) | 1998-06-08 | 2003-04-01 | Theravance, Inc. | β2-adrenergic receptor agonists |
US6576793B1 (en) | 1999-12-08 | 2003-06-10 | Theravance, Inc. | β2-adrenergic receptor agonists |
US6667344B2 (en) | 2001-04-17 | 2003-12-23 | Dey, L.P. | Bronchodilating compositions and methods |
US6683115B2 (en) | 1999-06-02 | 2004-01-27 | Theravance, Inc. | β2-adrenergic receptor agonists |
US6713651B1 (en) | 1999-06-07 | 2004-03-30 | Theravance, Inc. | β2-adrenergic receptor agonists |
US7348362B2 (en) | 2003-07-10 | 2008-03-25 | Dey, L.P. | Bronchodilating β-agonist compositions and methods |
WO2009032764A1 (en) | 2007-08-28 | 2009-03-12 | Sepracor Inc. | Acetamide stereoisomer |
US8173829B2 (en) | 2007-08-28 | 2012-05-08 | Sunovion Pharmaceuticals Inc. | Carbamate stereoisomer |
US8507670B2 (en) | 2006-08-22 | 2013-08-13 | Ranbaxy Laboratories Limited | Matrix metalloproteinase inhibitors |
US8623851B2 (en) | 2001-04-17 | 2014-01-07 | Mylan Specialty L.P. | Formoterol/steroid bronchodilating compositions and methods of use thereof |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BE739678A (fr) * | 1969-10-01 | 1970-04-01 | Amino-alcools et leur preparation |
-
1973
- 1973-02-02 DE DE19732366625 patent/DE2366625C2/de not_active Expired
- 1973-02-02 DE DE19732305092 patent/DE2305092A1/de active Granted
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BE739678A (fr) * | 1969-10-01 | 1970-04-01 | Amino-alcools et leur preparation |
Cited By (33)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4072760A (en) * | 1974-11-20 | 1978-02-07 | Pharmacia As | Bronchospasmolytic phenylethanolamines |
EP0068669A1 (en) * | 1981-06-20 | 1983-01-05 | Beecham Group Plc | Secondary phenylethanol amines, processes for their preparation and their pharmaceutical application |
EP0180994A2 (en) * | 1984-11-08 | 1986-05-14 | Syntex (U.S.A.) Inc. | Antihypertensive dialkyl aminoethylaniline derivatives |
EP0180994A3 (en) * | 1984-11-08 | 1987-09-23 | Syntex (U.S.A.) Inc. | Antihypertensive dialkyl aminoethylaniline derivatives |
US4975466A (en) * | 1986-06-05 | 1990-12-04 | Ciba-Geigy Corporation | Pharmaceutical preparations for topical application and their use in the treatment of inflammatory skin diseases |
LT3813B (en) | 1990-09-26 | 1996-03-25 | Astra Ab | Process for preparing 3-formamido-4-hydroxy-alpha£n£1-methyl-2(p-methoxyphenyl)ethylaminomethyl|benzyl alkohol fumarate (formoterol) and related compounds and derivatives thereof |
EP0586344A1 (de) * | 1992-09-02 | 1994-03-09 | Ciba-Geigy Ag | Oxazolidin Verbindungen und ihre Verwendung als Arzneimittel |
US6541669B1 (en) | 1998-06-08 | 2003-04-01 | Theravance, Inc. | β2-adrenergic receptor agonists |
US6683115B2 (en) | 1999-06-02 | 2004-01-27 | Theravance, Inc. | β2-adrenergic receptor agonists |
US6713651B1 (en) | 1999-06-07 | 2004-03-30 | Theravance, Inc. | β2-adrenergic receptor agonists |
US6576793B1 (en) | 1999-12-08 | 2003-06-10 | Theravance, Inc. | β2-adrenergic receptor agonists |
US8716348B2 (en) | 2001-04-17 | 2014-05-06 | Dey Pharma, L.P. | Formoterol/steroid bronchodilating compositions and methods of use thereof |
US8623851B2 (en) | 2001-04-17 | 2014-01-07 | Mylan Specialty L.P. | Formoterol/steroid bronchodilating compositions and methods of use thereof |
US9597396B2 (en) | 2001-04-17 | 2017-03-21 | Mylan Specialty Lp | Formoterol/steroid bronchodilating compositions and methods of use thereof |
US6667344B2 (en) | 2001-04-17 | 2003-12-23 | Dey, L.P. | Bronchodilating compositions and methods |
US7462645B2 (en) | 2003-07-10 | 2008-12-09 | Jpmorgan Chase Bank, N.A. | Bronchodilating beta-agonist compositions and methods |
US7465756B2 (en) | 2003-07-10 | 2008-12-16 | Jpmorgan Chase Bank, N.A. | Bronchodilating beta-agonist compositions and methods |
US7473710B2 (en) | 2003-07-10 | 2009-01-06 | Jpmorgan Chase Bank, N.A. | Bronchodilating beta-agonist compositions and methods |
US9730890B2 (en) | 2003-07-10 | 2017-08-15 | Mylan Pharmaceuticals, Inc. | Bronchodilating beta-agonist compositions and methods |
US7541385B2 (en) | 2003-07-10 | 2009-06-02 | Chaudry Imtiaz A | Bronchodilating β-agonist compositions and methods |
US7348362B2 (en) | 2003-07-10 | 2008-03-25 | Dey, L.P. | Bronchodilating β-agonist compositions and methods |
US8846910B2 (en) | 2006-08-22 | 2014-09-30 | Ranbaxy Laboratories Limited | Matrix metalloproteinase inhibitors |
US8507670B2 (en) | 2006-08-22 | 2013-08-13 | Ranbaxy Laboratories Limited | Matrix metalloproteinase inhibitors |
US8816073B2 (en) | 2006-08-22 | 2014-08-26 | Ranbaxy Laboratories Limited | Matrix metalloproteinase inhibitors |
AU2008296458B2 (en) * | 2007-08-28 | 2014-01-16 | Sunovion Pharmaceuticals Inc. | Acetamide stereoisomer |
US8664441B2 (en) | 2007-08-28 | 2014-03-04 | Sunovion Pharmaceuticals Inc. | Acetamide stereoisomer |
KR101398775B1 (ko) * | 2007-08-28 | 2014-05-27 | 선오비온 파마슈티컬스 인코포레이티드 | 아세트아미드 입체이성체 |
US8501994B2 (en) | 2007-08-28 | 2013-08-06 | Sunovion Pharmaceuticals Inc. | Acetamide stereoisomer |
US9040588B2 (en) | 2007-08-28 | 2015-05-26 | Sunovion Pharmaceuticals Inc. | Acetamide stereoisomer |
TWI505826B (zh) * | 2007-08-28 | 2015-11-01 | Sepracor Inc | 乙醯胺立體異構物 |
US9499476B2 (en) | 2007-08-28 | 2016-11-22 | Sunovion Pharmaceuticals Inc. | Acetamide stereoisomer |
US8173829B2 (en) | 2007-08-28 | 2012-05-08 | Sunovion Pharmaceuticals Inc. | Carbamate stereoisomer |
WO2009032764A1 (en) | 2007-08-28 | 2009-03-12 | Sepracor Inc. | Acetamide stereoisomer |
Also Published As
Publication number | Publication date |
---|---|
DE2305092C2 (hu) | 1987-10-01 |
DE2366625C2 (hu) | 1988-06-09 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DE69100079T2 (de) | Naphthalin-Derivate, Verfahren zu ihrer Herstellung und sie enthaltende pharmazeutische Zusammensetzungen. | |
DE69032020T2 (de) | N-Substituierte 4-Pyrimidinamine und -Pyrimidindiamine, Verfahren zu ihrer Herstellung und ihre Anwendung als Arzneimittel | |
DD141520A5 (de) | Verfahren zur herstellung neuer derivate von 4-amino-5-alkylsulfonyl-ortho-anisamiden | |
DE2305092A1 (de) | Alpha-aminomethylbenzylalkoholderivate | |
DE9290063U1 (de) | Chinuclidin-Derivate | |
CH631696A5 (de) | Verfahren zur herstellung von olefinischen derivaten von aminosaeuren. | |
EP0929516A1 (de) | Benzamidinderivate und ihre verwendung als arzneimittel mit ltb4-antagonistischer wirkung | |
DD216934A5 (de) | Verfahren zur herstellung neuer derivate von xanthinen | |
DE2105743A1 (en) | 2-(furylmethyl)-6,7-benzomorphans - useful as cns active agents | |
DE2720085C2 (hu) | ||
EP0521422B1 (de) | Benzomorphane und ihre Verwendung als Arzneimittel | |
DE3586411T2 (de) | Dopamin-antagoniste. | |
DE69002474T2 (de) | Carboxyalkyl-ether von 2-Amino-7-hydroxytetralin. | |
EP0064685A1 (de) | Dibenzo(de,g)chinolin-Derivate, Verfahren zu deren Herstellung und diese enthaltende Arzneimittel | |
CH622768A5 (hu) | ||
CH640507A5 (en) | Process for preparing novel 1-aryloxy-2-hydroxy-3-aminopropanes | |
DE2241241C3 (de) | Thiazolo eckige klammer auf 3.2-a eckige klammer zu -pyrimidinderivate, verfahren zu ihrer herstellung und sie enthaltende arzneimittel | |
CH624397A5 (hu) | ||
EP0102929B1 (de) | Propylamin-Derivate, Verfahren zu ihrer Herstellung, pharmazeutische Präparate enthaltend diese Verbindungen, sowie ihre therapeutische Verwendung | |
DE829894C (de) | Verfahren zur Herstellung neuer Derivate von 1, 8-Naphthyridin-4-carbonsaeuren | |
DD215540A5 (de) | Verfahren zur herstellung von benzazepinderivaten | |
DE1901167C3 (de) | Substituierte Indole, Verfahren zu ihrer Herstellung und pharmazeutische Zusammensetzungen | |
CH556323A (de) | Verfahren zur herstellung von neuen naphthylalkylaminen. | |
DE2500919C3 (de) | 5-(l-Allyl-2-pyrrolidinylmethylaminocarbonyl)-6-methoxy-benzotriazol sowie seine pharmazeutisch verträglichen Additionssalze mit Säuren | |
AT282593B (de) | Verfahren zur herstellung von neuem racemischem oder optisch aktivem (1-2'-nitrilophenoxy)-2-hydroxy-3-isopropylaminopropan und dessen salzen |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
OD | Request for examination | ||
8172 | Supplementary division/partition in: |
Ref country code: DE Ref document number: 2366624 Format of ref document f/p: P |
|
Q171 | Divided out to: |
Ref country code: DE Ref document number: 2366624 |
|
8172 | Supplementary division/partition in: |
Ref country code: DE Ref document number: 2366625 Format of ref document f/p: P |
|
Q171 | Divided out to: |
Ref country code: DE Ref document number: 2366625 |
|
AH | Division in |
Ref country code: DE Ref document number: 2366625 Format of ref document f/p: P |
|
D2 | Grant after examination | ||
8364 | No opposition during term of opposition | ||
AH | Division in |
Ref country code: DE Ref document number: 2366625 Format of ref document f/p: P |