DE122008000058I1 - Rekombinante influenzaviren zur vakzinherstellung und gentherapie - Google Patents

Rekombinante influenzaviren zur vakzinherstellung und gentherapie

Info

Publication number: DE122008000058I1
Authority: DE; Germany
Prior art keywords: vaccination; gene therapy; influenza viruses; recombinant influenza; viruses
Prior art date: 1999-04-06
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Pending

Application number

DE122008000058C

Other languages

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Wisconsin Alumni Research Foundation

Original Assignee

Wisconsin Alumni Research Foundation

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-04-06

Filing date

2000-04-05

Publication date

2009-05-07

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26826080&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE122008000058(I1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2000-04-05 Application filed by Wisconsin Alumni Research Foundation filed Critical Wisconsin Alumni Research Foundation

2009-05-07 Publication of DE122008000058I1 publication Critical patent/DE122008000058I1/de

Status Pending legal-status Critical Current

Links

241000700605 Viruses Species 0.000 title abstract 2
238000001415 gene therapy Methods 0.000 title 1
206010022000 influenza Diseases 0.000 title 1
238000002255 vaccination Methods 0.000 title 1
241000712431 Influenza A virus Species 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5258—Virus-like particles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16111—Influenzavirus A, i.e. influenza A virus
- C12N2760/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16111—Influenzavirus A, i.e. influenza A virus
- C12N2760/16123—Virus like particles [VLP]
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16111—Influenzavirus A, i.e. influenza A virus
- C12N2760/16141—Use of virus, viral particle or viral elements as a vector
- C12N2760/16143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2800/00—Nucleic acids vectors
- C12N2800/30—Vector systems comprising sequences for excision in presence of a recombinase, e.g. loxP or FRT
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2810/00—Vectors comprising a targeting moiety
- C12N2810/50—Vectors comprising as targeting moiety peptide derived from defined protein
- C12N2810/60—Vectors comprising as targeting moiety peptide derived from defined protein from viruses
- C12N2810/6072—Vectors comprising as targeting moiety peptide derived from defined protein from viruses negative strand RNA viruses
- C12N2810/6081—Vectors comprising as targeting moiety peptide derived from defined protein from viruses negative strand RNA viruses rhabdoviridae, e.g. VSV

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Genetics & Genomics (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
General Health & Medical Sciences (AREA)
Wood Science & Technology (AREA)
Zoology (AREA)
Virology (AREA)
General Engineering & Computer Science (AREA)
Biotechnology (AREA)
Biomedical Technology (AREA)
Medicinal Chemistry (AREA)
Molecular Biology (AREA)
Immunology (AREA)
Biochemistry (AREA)
Microbiology (AREA)
Biophysics (AREA)
General Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Physics & Mathematics (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Plant Pathology (AREA)
Chemical Kinetics & Catalysis (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Pulmonology (AREA)
Gastroenterology & Hepatology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)

DE122008000058C 1999-04-06 2000-04-05 Rekombinante influenzaviren zur vakzinherstellung und gentherapie Pending DE122008000058I1 (de)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US12791299P	1999-04-06	1999-04-06
US13283999P	1999-05-06	1999-05-06
PCT/US2000/009021 WO2000060050A2 (en)	1999-04-06	2000-04-05	Recombinant influenza viruses for vaccines and gene therapy

Publications (1)

Publication Number	Publication Date
DE122008000058I1 true DE122008000058I1 (de)	2009-05-07

Family

ID=26826080

Family Applications (6)

Application Number	Title	Priority Date	Filing Date
DE122008000035C Pending DE122008000035I1 (de)	1999-04-06	2000-04-05	Rekombinante influenzaviren zur vakzinherstellung und gentherapie
DE122008000061C Pending DE122008000061I1 (de)	1999-04-06	2000-04-05	Rekombinante influenzaviren zur vakzinherstellung und gentherapie
DE200812000014 Pending DE122008000014I1 (de)	1999-04-06	2000-04-05	Rekombinante influenzaviren zur vakzinherstellung und gentherapie.
DE122008000058C Pending DE122008000058I1 (de)	1999-04-06	2000-04-05	Rekombinante influenzaviren zur vakzinherstellung und gentherapie
DE60035778T Expired - Lifetime DE60035778T2 (de)	1999-04-06	2000-04-05	Rekombinante influenzaviren zur vakzinherstellung und gentherapie
DE201112100037 Pending DE122011100037I1 (de)	1999-04-06	2011-07-26	Rekombinante influenzaviren zur vakzinherstellung und gentherapie.

Family Applications Before (3)

Application Number	Title	Priority Date	Filing Date
DE122008000035C Pending DE122008000035I1 (de)	1999-04-06	2000-04-05	Rekombinante influenzaviren zur vakzinherstellung und gentherapie
DE122008000061C Pending DE122008000061I1 (de)	1999-04-06	2000-04-05	Rekombinante influenzaviren zur vakzinherstellung und gentherapie
DE200812000014 Pending DE122008000014I1 (de)	1999-04-06	2000-04-05	Rekombinante influenzaviren zur vakzinherstellung und gentherapie.

Family Applications After (2)

Application Number	Title	Priority Date	Filing Date
DE60035778T Expired - Lifetime DE60035778T2 (de)	1999-04-06	2000-04-05	Rekombinante influenzaviren zur vakzinherstellung und gentherapie
DE201112100037 Pending DE122011100037I1 (de)	1999-04-06	2011-07-26	Rekombinante influenzaviren zur vakzinherstellung und gentherapie.

Country Status (19)

Country	Link
EP (4)	EP2910629B1 (de)
JP (3)	JP5543048B2 (de)
KR (1)	KR100702275B1 (de)
CN (2)	CN101851636B (de)
AT (2)	ATE368729T1 (de)
AU (1)	AU4073300A (de)
BR (1)	BRPI0009580B8 (de)
CA (2)	CA2928263A1 (de)
CY (2)	CY1108520T1 (de)
DE (6)	DE122008000035I1 (de)
DK (3)	DK1185615T3 (de)
ES (3)	ES2373405T3 (de)
FR (1)	FR11C0027I2 (de)
HK (2)	HK1148778A1 (de)
IL (2)	IL145702A0 (de)
MX (1)	MXPA01010082A (de)
NL (2)	NL300365I2 (de)
PT (2)	PT1820853E (de)
WO (1)	WO2000060050A2 (de)

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ES2563402T3 (es)	2002-02-13	2016-03-15	Wisconsin Alumni Research Foundation	Señal para el empaquetamiento de vectores del virus de la gripe
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EP2581093B1 (de)	2003-06-16	2015-03-18	MedImmune, LLC	Influenza-Hämagglutinin- und Neuraminidase-Varianten
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EP1722815A1 (de)	2004-03-09	2006-11-22	Chiron Corporation	Influenza-virus-vakzine
EP1771552B1 (de)	2004-05-25	2012-08-01	MedImmune Vaccines, Inc.	Influenza-hämagglutinin- und neuraminidase-varianten
US7968101B2 (en)	2004-11-19	2011-06-28	Wisconsin Alumni Research Foundation	Recombinant influenza vectors with tandem transcription units
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BRPI0518568A2 (pt)	2004-12-24	2008-11-25	Solvay Pharm Bv	mÉtodo para produzir uma partÍcula do vÍrus da influenza replicativo sem o uso de vÍrus auxiliar, partÍcula de vÍrus da influenza replicativo, cÉlula, composiÇço, uso de uma composiÇço, mÉtodo para gerar proteÇço imunolàgica contra infecÇço de um indivÍduo com um vÍrus da influenza, e, Ácido nuclÉico
EP2471552B1 (de)	2005-03-08	2015-05-06	MedImmune, LLC	Reassortierte Influenza-Viren
US11707520B2 (en)	2005-11-03	2023-07-25	Seqirus UK Limited	Adjuvanted vaccines with non-virion antigens prepared from influenza viruses grown in cell culture
KR20080069232A (ko)	2005-11-04	2008-07-25	노바티스 백신즈 앤드 다이아그노스틱스 에스.알.엘.	스플리트 인플루엔자 백신에 대한 보조제로서 유리 수성상계면활성제를 갖는 에멀젼
PL2368572T3 (pl)	2005-11-04	2020-11-16	Seqirus UK Limited	Szczepionki z adjuwantem z niewirionowymi antygenami otrzymane z wirusów grypy hodowanych w hodowli komórkowej
US8697087B2 (en)	2005-11-04	2014-04-15	Novartis Ag	Influenza vaccines including combinations of particulate adjuvants and immunopotentiators
CA2628424A1 (en)	2005-11-04	2007-05-10	Novartis Vaccines And Diagnostics S.R.L.	Adjuvanted influenza vaccines including cytokine-inducing agents
ES2668018T3 (es)	2005-12-02	2018-05-16	Icahn School Of Medicine At Mount Sinai	Virus quiméricos de la enfermedad de Newcastle que presentan proteínas de superficie no naturales y sus usos
BRPI0707300B8 (pt)	2006-01-27	2021-05-25	Novartis Ag	vacina contra vírion influenza dividido ou antígeno de superfície purificado e método para a preparação de uma composição imunogênica
EP2004226A1 (de)	2006-03-24	2008-12-24	Novartis Vaccines and Diagnostics GmbH & Co. KG	Lagerung von grippeimpfstoffen ohne kühlung
EP2010557B1 (de)	2006-03-31	2014-02-26	Wisconsin Alumni Research Foundation	Hochtitrige rekombinante influenzaviren für impfstoffe
US20090017444A1 (en) *	2006-06-09	2009-01-15	Wisconsin Alumni Research Foundation	Screening method for modulators of viral transcription or replication
GB0614460D0 (en)	2006-07-20	2006-08-30	Novartis Ag	Vaccines
WO2008133701A1 (en)	2006-07-21	2008-11-06	Medimmune, Llc.	Methods and compositions for increasing replication capacity of an influenza virus
KR101559184B1 (ko)	2006-08-09	2015-10-13	메디뮨 엘엘씨	인플루엔자 헤마글루티닌 및 뉴라미니다제 변이체
BRPI0716536A2 (pt)	2006-09-11	2013-09-24	Novartis Ag	produÇço de vacinas de vÍrus influenza, sem a utilizaÇço de ovos
EP2121011B1 (de)	2006-12-06	2014-05-21	Novartis AG	Impfstoffe mit antigen aus vier stämmen des influenzavirus
US8597661B2 (en)	2007-05-04	2013-12-03	Wisconsin Alumni Research Foundation	Neuraminidase-deficient live influenza vaccines
US9474798B2 (en)	2007-06-18	2016-10-25	Wisconsin Alumni Research Foundation	Influenza M2 protein mutant viruses as live influenza attenuated vaccines
EP2069484B1 (de)	2007-06-18	2014-08-13	MedImmune, LLC	Influenza-B-Viruses mit verändertem Hämagglutininpolypeptid
EP2045323A1 (de) *	2007-10-05	2009-04-08	Avir Green Hills Biotechnology Research Development Trade Ag	Linearische Expressionskonstrukte zur Herstellung von Partikeln des Influenzavirus
DK2185191T3 (da)	2007-06-27	2012-12-03	Novartis Ag	Influenzavacciner med lavt indhold af tilsætningsstoffer
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EP2233568A1 (de)	2009-03-19	2010-09-29	Avir Green Hills Biotechnology Research Development Trade AG	Neues Verfahren zur Herstellung eines RNA Virus
CA2752041A1 (en)	2009-02-10	2010-08-19	Novartis Ag	Influenza vaccines with increased amounts of h3 antigen
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JP5642712B2 (ja)	2009-02-10	2014-12-17	ノバルティスアーゲー	少ない量のスクアレンを含むインフルエンザワクチン
AU2010213966B2 (en)	2009-02-12	2015-01-22	Medimmune, Llc	Influenza hemagglutinin and neuraminidase variants
EP2424565A1 (de)	2009-04-27	2012-03-07	Novartis AG	Adjuvantierte impfstoffe zum schutz vor grippe
AU2010293902A1 (en)	2009-09-10	2012-03-22	Novartis Ag	Combination vaccines against respiratory tract diseases
ES2813347T3 (es)	2009-10-26	2021-03-23	Wisconsin Alumni Res Found	Virus recombinantes de la influenza de alto título con replicación mejorada en células Vero
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Also Published As

Publication number	Publication date
FR11C0027I2 (fr)	2021-12-31
EP2345716A1 (de)	2011-07-20
EP1185615A2 (de)	2002-03-13
AU4073300A (en)	2000-10-23
DE122011100037I1 (de)	2012-03-22
EP1820853A2 (de)	2007-08-22
CN1350578B (zh)	2010-05-12
EP1820853B1 (de)	2011-09-21
DE122008000061I1 (de)	2009-02-12
BR0009580A (pt)	2002-01-02
ATE525461T1 (de)	2011-10-15
DE122008000035I1 (de)	2009-05-20
NL300364I2 (nl)	2017-08-03
JP2011182797A (ja)	2011-09-22
CN101851636A (zh)	2010-10-06
ES2290024T3 (es)	2008-02-16
JP2015119735A (ja)	2015-07-02
ES2373405T3 (es)	2012-02-03
BRPI0009580B8 (pt)	2021-05-25
NL300365I1 (nl)	2009-01-05
HK1148778A1 (zh)	2011-09-16
CN101851636B (zh)	2015-11-25
PT1185615E (pt)	2007-10-04
IL145702A0 (en)	2002-07-25
JP5775351B2 (ja)	2015-09-09
CA2928263A1 (en)	2000-10-12
EP1185615B1 (de)	2007-08-01
WO2000060050A2 (en)	2000-10-12
KR100702275B1 (ko)	2007-03-30
DE60035778D1 (de)	2007-09-13
JP5543048B2 (ja)	2014-07-09
CA2365526A1 (en)	2000-10-12
EP2345716B1 (de)	2015-01-14
HK1214298A1 (zh)	2016-07-22
EP2910629A1 (de)	2015-08-26
DK2345716T3 (en)	2015-02-09
JP6224645B2 (ja)	2017-11-01
CY1108520T1 (el)	2014-04-09
KR20010113044A (ko)	2001-12-24
FR11C0027I1 (fr)	2011-08-26
ATE368729T1 (de)	2007-08-15
CA2365526C (en)	2016-07-05
WO2000060050A3 (en)	2001-01-18
MXPA01010082A (es)	2002-04-24
NL300365I2 (nl)	2017-08-03
CY1112140T1 (el)	2015-11-04
ES2533622T3 (es)	2015-04-13
DK1185615T3 (da)	2007-11-05
PT1820853E (pt)	2012-01-03
DE122008000014I1 (de)	2011-12-01
EP1820853A3 (de)	2007-10-03
EP2910629B1 (de)	2018-09-19
DE60035778T2 (de)	2008-04-30
CN1350578A (zh)	2002-05-22
IL145702A (en)	2010-04-15
NL300364I1 (nl)	2009-01-05
DK1820853T3 (da)	2011-12-19
BR0009580B1 (pt)	2014-11-25
JP2003528570A (ja)	2003-09-30

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