DE112009000171A5 - Vorrichtung zum optischen Abbilden einer Probe - Google Patents

Vorrichtung zum optischen Abbilden einer Probe Download PDF

Info

Publication number
DE112009000171A5
DE112009000171A5 DE112009000171T DE112009000171T DE112009000171A5 DE 112009000171 A5 DE112009000171 A5 DE 112009000171A5 DE 112009000171 T DE112009000171 T DE 112009000171T DE 112009000171 T DE112009000171 T DE 112009000171T DE 112009000171 A5 DE112009000171 A5 DE 112009000171A5
Authority
DE
Germany
Prior art keywords
sample
optically imaging
optically
imaging
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
DE112009000171T
Other languages
English (en)
Inventor
Hans-Ulrich Dodt
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dodt Hans-Ulrich Prof Dr
Original Assignee
Dodt Hans-Ulrich Prof Dr
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dodt Hans-Ulrich Prof Dr filed Critical Dodt Hans-Ulrich Prof Dr
Publication of DE112009000171A5 publication Critical patent/DE112009000171A5/de
Ceased legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N21/6456—Spatial resolved fluorescence measurements; Imaging
    • G01N21/6458—Fluorescence microscopy
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6486—Measuring fluorescence of biological material, e.g. DNA, RNA, cells
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/0004—Microscopes specially adapted for specific applications
    • G02B21/002—Scanning microscopes
    • G02B21/0024—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
    • G02B21/0052—Optical details of the image generation
    • G02B21/0076—Optical details of the image generation arrangements using fluorescence or luminescence
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/02—Investigating particle size or size distribution
    • G01N15/0205—Investigating particle size or size distribution by optical means
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B1/00—Optical elements characterised by the material of which they are made; Optical coatings for optical elements
    • G02B1/10—Optical coatings produced by application to, or surface treatment of, optical elements
    • G02B1/16—Optical coatings produced by application to, or surface treatment of, optical elements having an anti-static effect, e.g. electrically conducting coatings

Landscapes

  • Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Optics & Photonics (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Microscoopes, Condenser (AREA)
DE112009000171T 2008-02-12 2009-02-12 Vorrichtung zum optischen Abbilden einer Probe Ceased DE112009000171A5 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AT2282008 2008-02-12
ATA228/2008 2008-02-12
PCT/EP2009/000997 WO2009100911A1 (de) 2008-02-12 2009-02-12 Vorrichtung zum optischen abbilden einer probe

Publications (1)

Publication Number Publication Date
DE112009000171A5 true DE112009000171A5 (de) 2011-02-10

Family

ID=40809912

Family Applications (1)

Application Number Title Priority Date Filing Date
DE112009000171T Ceased DE112009000171A5 (de) 2008-02-12 2009-02-12 Vorrichtung zum optischen Abbilden einer Probe

Country Status (3)

Country Link
US (1) US9759661B2 (de)
DE (1) DE112009000171A5 (de)
WO (1) WO2009100911A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5766210B2 (ja) 2010-01-15 2015-08-19 コーニンクレッカ フィリップス エヌ ヴェ 誘導放出抑制顕微鏡システム
DE102010060121C5 (de) 2010-10-22 2023-09-28 Leica Microsystems Cms Gmbh SPIM-Mikroskop mit sequenziellem Lightsheet
DE102013002981B4 (de) 2013-02-20 2022-04-28 Hans-Ulrich Dodt 3D-Mikroskop

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4188120A (en) * 1978-01-06 1980-02-12 The United States Of America As Represented By The Secretary Of The Navy Radioiodine detector based on laser induced fluorescence
US6548796B1 (en) * 1999-06-23 2003-04-15 Regents Of The University Of Minnesota Confocal macroscope
WO2003060477A2 (en) * 2002-01-10 2003-07-24 The Regents Of The University Of California Iterative optical based histology
US7064824B2 (en) 2003-04-13 2006-06-20 Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E.V. High spatial resoulution imaging and modification of structures
DE102005020003B4 (de) 2005-04-27 2007-10-11 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Fluoreszenzmikroskop
DE102006062823B4 (de) 2006-03-01 2010-11-25 Leica Microsystems Cms Gmbh Verfahren und Mikroskop zur räumlich hochauflösenden Untersuchung von Proben
US7679741B2 (en) * 2006-03-01 2010-03-16 Leica Microsystems Cms Gmbh Method and microscope for high spatial resolution examination of samples

Also Published As

Publication number Publication date
WO2009100911A1 (de) 2009-08-20
US9759661B2 (en) 2017-09-12
US20110186754A1 (en) 2011-08-04

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R012 Request for examination validly filed
R002 Refusal decision in examination/registration proceedings
R003 Refusal decision now final