DE10193213T1 - Analyseinstrument - Google Patents
Analyseinstrument Download PDFInfo
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- DE10193213T1 DE10193213T1 DE10193213T DE10193213T DE10193213T1 DE 10193213 T1 DE10193213 T1 DE 10193213T1 DE 10193213 T DE10193213 T DE 10193213T DE 10193213 T DE10193213 T DE 10193213T DE 10193213 T1 DE10193213 T1 DE 10193213T1
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- Germany
- Prior art keywords
- instrument according
- analytical instrument
- capillary
- substrate
- sample chamber
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/1486—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using enzyme electrodes, e.g. with immobilised oxidase
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/15—Devices for taking samples of blood
- A61B5/150007—Details
- A61B5/150015—Source of blood
- A61B5/150022—Source of blood for capillary blood or interstitial fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/15—Devices for taking samples of blood
- A61B5/150007—Details
- A61B5/150053—Details for enhanced collection of blood or interstitial fluid at the sample site, e.g. by applying compression, heat, vibration, ultrasound, suction or vacuum to tissue; for reduction of pain or discomfort; Skin piercing elements, e.g. blades, needles, lancets or canulas, with adjustable piercing speed
- A61B5/150061—Means for enhancing collection
- A61B5/150099—Means for enhancing collection by negative pressure, other than vacuum extraction into a syringe by pulling on the piston rod or into pre-evacuated tubes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/15—Devices for taking samples of blood
- A61B5/150007—Details
- A61B5/150206—Construction or design features not otherwise provided for; manufacturing or production; packages; sterilisation of piercing element, piercing device or sampling device
- A61B5/150221—Valves
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/15—Devices for taking samples of blood
- A61B5/150007—Details
- A61B5/150358—Strips for collecting blood, e.g. absorbent
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/15—Devices for taking samples of blood
- A61B5/151—Devices specially adapted for taking samples of capillary blood, e.g. by lancets, needles or blades
- A61B5/15101—Details
- A61B5/15115—Driving means for propelling the piercing element to pierce the skin, e.g. comprising mechanisms based on shape memory alloys, magnetism, solenoids, piezoelectric effect, biased elements, resilient elements, vacuum or compressed fluids
- A61B5/15117—Driving means for propelling the piercing element to pierce the skin, e.g. comprising mechanisms based on shape memory alloys, magnetism, solenoids, piezoelectric effect, biased elements, resilient elements, vacuum or compressed fluids comprising biased elements, resilient elements or a spring, e.g. a helical spring, leaf spring, or elastic strap
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/15—Devices for taking samples of blood
- A61B5/151—Devices specially adapted for taking samples of capillary blood, e.g. by lancets, needles or blades
- A61B5/15101—Details
- A61B5/15115—Driving means for propelling the piercing element to pierce the skin, e.g. comprising mechanisms based on shape memory alloys, magnetism, solenoids, piezoelectric effect, biased elements, resilient elements, vacuum or compressed fluids
- A61B5/15123—Driving means for propelling the piercing element to pierce the skin, e.g. comprising mechanisms based on shape memory alloys, magnetism, solenoids, piezoelectric effect, biased elements, resilient elements, vacuum or compressed fluids comprising magnets or solenoids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/15—Devices for taking samples of blood
- A61B5/151—Devices specially adapted for taking samples of capillary blood, e.g. by lancets, needles or blades
- A61B5/15186—Devices loaded with a single lancet, i.e. a single lancet with or without a casing is loaded into a reusable drive device and then discarded after use; drive devices reloadable for multiple use
- A61B5/15188—Constructional features of reusable driving devices
- A61B5/1519—Constructional features of reusable driving devices comprising driving means, e.g. a spring, for propelling the piercing unit
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/15—Devices for taking samples of blood
- A61B5/151—Devices specially adapted for taking samples of capillary blood, e.g. by lancets, needles or blades
- A61B5/15186—Devices loaded with a single lancet, i.e. a single lancet with or without a casing is loaded into a reusable drive device and then discarded after use; drive devices reloadable for multiple use
- A61B5/15188—Constructional features of reusable driving devices
- A61B5/15192—Constructional features of reusable driving devices comprising driving means, e.g. a spring, for retracting the lancet unit into the driving device housing
- A61B5/15194—Constructional features of reusable driving devices comprising driving means, e.g. a spring, for retracting the lancet unit into the driving device housing fully automatically retracted, i.e. the retraction does not require a deliberate action by the user, e.g. by terminating the contact with the patient's skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/15—Devices for taking samples of blood
- A61B5/157—Devices characterised by integrated means for measuring characteristics of blood
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/0627—Sensor or part of a sensor is integrated
- B01L2300/0645—Electrodes
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0809—Geometry, shape and general structure rectangular shaped
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0809—Geometry, shape and general structure rectangular shaped
- B01L2300/0825—Test strips
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0887—Laminated structure
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/10—Means to control humidity and/or other gases
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
- B01L2400/0406—Moving fluids with specific forces or mechanical means specific forces capillary forces
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/28—Electrolytic cell components
- G01N27/30—Electrodes, e.g. test electrodes; Half-cells
- G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
- G01N27/3271—Amperometric enzyme electrodes for analytes in body fluids, e.g. glucose in blood
- G01N27/3272—Test elements therefor, i.e. disposable laminated substrates with electrodes, reagent and channels
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Physics & Mathematics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Pathology (AREA)
- Biomedical Technology (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- Biophysics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Hematology (AREA)
- Chemical & Material Sciences (AREA)
- Optics & Photonics (AREA)
- Manufacturing & Machinery (AREA)
- Dispersion Chemistry (AREA)
- Clinical Laboratory Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Dermatology (AREA)
- Pain & Pain Management (AREA)
- Analytical Chemistry (AREA)
- Emergency Medicine (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
- Sampling And Sample Adjustment (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
- Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
- Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
Abstract
Analyseinstrument, mit: einem Substrat (1); einer Vielzahl von Elektroden (11, 12, 13) auf dem Substrat; einer Abdeckung (2); Abstandsmitteln (3), die zwischen dem Substrat und der Abdeckung angeordnet sind, wobei die Abstandsmittel (3) untereinander beabstandete Abschnitte aufweisen; und einer Probenkammer (4, 5), die oben und unten zwischen der Abdeckung (2) und dem Substrat (1) und seitlich zwischen den untereinander beabstandeten Abschnitten der Abstandsmittel (3) definiert ist; wobei die Probenkammer (4, 5) eine Kapillare (5) und einen Flüssigkeitssammelabschnitt (4) mit gekrümmten Seitenwänden aufweist, der mit der Kapillare (5) in Verbindung ist und einen Abschnitt aufweist, der breiter als die Kapillare (5) ist.
Claims (23)
- Analyseinstrument, mit: einem Substrat (
1 ); einer Vielzahl von Elektroden (11 ,12 ,13 ) auf dem Substrat; einer Abdeckung (2 ); Abstandsmitteln (3 ), die zwischen dem Substrat und der Abdeckung angeordnet sind, wobei die Abstandsmittel (3 ) untereinander beabstandete Abschnitte aufweisen; und einer Probenkammer (4 ,5 ), die oben und unten zwischen der Abdeckung (2 ) und dem Substrat (1 ) und seitlich zwischen den untereinander beabstandeten Abschnitten der Abstandsmittel (3 ) definiert ist; wobei die Probenkammer (4 ,5 ) eine Kapillare (5 ) und einen Flüssigkeitssammelabschnitt (4 ) mit gekrümmten Seitenwänden aufweist, der mit der Kapillare (5 ) in Verbindung ist und einen Abschnitt aufweist, der breiter als die Kapillare (5 ) ist. - Analyseinstrument nach Anspruch 1, bei dem das Substrat (
1 ) oder die Abdeckung (2 ) mit einer Aussparung ausgebildet ist, die eine Öffnung für den Flüssigkeitssammelabschnitt (4 ) der Probenkammer definiert. - Analyseinstrument nach Anspruch 1 oder 2, bei dem die gekrümmten Seitenwände des Flüssigkeitssammelabschnitts durch das Abstandsmittel definiert sind.
- Analyseinstrument nach Anspruch 2 oder Anspruch 3, wenn abhängig von Anspruch 2, bei dem die gekrümmten Seitenwände des Flüssigkeitssammelabschnitts entlang der Aussparung gekrümmt sind.
- Analyseinstrument nach einem der Ansprüche 1 bis 4, bei dem sich die gekrümmten Seitenwände des Flüssigkeitssammelabschnitts (
4 ) von der Kapillare (5 ) auf eine konkave Weise erstrecken, um den Abschnitt zu definieren, der breiter als die Kapillare ist. - Analyseinstrument nach einem der Ansprüche 1 bis 5, bei dem eine Breite der Probenkammer in dem Flüssigkeitssammelabschnitt (
4 ) abnimmt und in der Kapillare (5 ) im Wesentlichen unverändert ist. - Analyseinstrument nach einem der Ansprüche 1 bis 6, bei dem die Probenkammer (
4 ,5 ) bei einer Überschneidung des Flüssigkeitssammelabschnitts (4 ) und der Kapillare (5 ) einen winkligen Übergangsabschnitt aufweist. - Analyseinstrument nach einem der vorstehenden Ansprüche, bei dem die Abdeckung (
2 ) einen transparenten oder lichtdurchlässigen Abschnitt aufweist. - Analyseinstrument nach einem der vorstehenden Ansprüche, bei dem mindestens eine der Flächen des Substrats oder der Abdeckung, die den Flüssigkeitssammelabschnitt (
4 ) definieren, eine Benetzbarkeit von nicht weniger als 57 mN/m aufweisen. - Analyseinstrument nach einem der vorstehenden Ansprüche, bei dem die Kapillare (
5 ) der Probenkammer eine Belüftung aufweist. - Analyseinstrument nach einem der vorstehenden Ansprüche, bei dem die Abmessungen der Probenkammer (
4 ,5 ) für in die Kapillare (5 ) durch Kapillarwirkung einzuziehendes Blut geeignet sind. - Analyseinstrument nach einem der vorstehenden Ansprüche, bei dem die Innenfläche des Substrats (
1 ) oder der Abdeckung (2 ) im Wesentlichen glatt ist. - Analyseinstrument nach Anspruch 12, bei dem die Innenflächen des Substrats (
1 ), der Abdeckung (2 ) und des Abstandsmittels (3 ) im Wesentlichen glatt sind. - Analyseinstrument nach einem der vorstehenden Ansprüche, bei dem eine Öffnung an der Kante der Probenkammer (
4 ,5 ) als eine Probeneinführöffnung dient. - Analyseinstrument nach einem der vorstehenden Ansprüche, bei dem die Kanten des Substrats (
1 ) und der Abdeckung (2 ) angrenzend an eine Öffnung der Kammer (4 ,5 ) im Wesentlichen zueinander ausgerichtet sind. - Analyseinstrument nach einem der vorstehenden Ansprüche, bei dem die Abdeckung (
2 ), das Substrat (1 ) und die Abstandsmittel (3 ) jeweils im Wesentlichen flach ist. - Analyseinstrument nach einem der vorstehenden Ansprüche, bei dem die Elektroden (
11 ,12 ) ein gabelförmiges Muster aufweisen. - Analyseinstrument nach einem der vorstehenden Ansprüche, bei dem die Elektroden (
11 ,12 ) angrenzend an die Kapillare auf dem Substrat angeordnet sind. - Analyseinstrument nach einem der vorstehenden Ansprüche, das eine Reagenzschicht (
13 ) aufweist, die in der Kapillare angeordnet ist. - Analyseinstrument nach einem der vorstehenden Ansprüche, bei dem eine Öffnung der Probenkammer (
4 ,5 ) eine Breite von weniger als in etwa 5 mm aufweist. - Analyseinstrument nach Anspruch 20, bei dem eine Öffnung der Probenkammer (
4 ,5 ) eine Breite von weniger als in etwa 3 mm aufweist. - Analyseinstrument nach einem der vorstehenden Ansprüche, bei dem eine Öffnung der Probenkammer (
4 ,5 ) eine Höhe von weniger als in etwa 200 μm aufweist. - Analyseinstrument nach einem der vorstehenden Ansprüche, bei dem eine Öffnung der Probenkammer (
4 ,5 ) eine Höhe von größer als in etwa 50 μm aufweist.
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2001227777 | 2001-07-27 | ||
JP2001227777 | 2001-07-27 | ||
JP2001242486 | 2001-08-09 | ||
JP2001242486 | 2001-08-09 | ||
EP10193213.5A EP2290358B1 (de) | 2001-07-27 | 2002-07-26 | Analyseinstrument |
Publications (2)
Publication Number | Publication Date |
---|---|
DE10193213T1 true DE10193213T1 (de) | 2013-01-31 |
DE10193213T8 DE10193213T8 (de) | 2013-04-25 |
Family
ID=26619436
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE10193213T Active DE10193213T8 (de) | 2001-07-27 | 2002-07-26 | Analyseinstrument |
Country Status (6)
Country | Link |
---|---|
US (2) | US7824616B2 (de) |
EP (2) | EP2290358B1 (de) |
JP (1) | JP4282477B2 (de) |
CN (1) | CN1300578C (de) |
DE (1) | DE10193213T8 (de) |
WO (1) | WO2003010530A1 (de) |
Families Citing this family (73)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6036924A (en) | 1997-12-04 | 2000-03-14 | Hewlett-Packard Company | Cassette of lancet cartridges for sampling blood |
US6391005B1 (en) | 1998-03-30 | 2002-05-21 | Agilent Technologies, Inc. | Apparatus and method for penetration with shaft having a sensor for sensing penetration depth |
US8641644B2 (en) | 2000-11-21 | 2014-02-04 | Sanofi-Aventis Deutschland Gmbh | Blood testing apparatus having a rotatable cartridge with multiple lancing elements and testing means |
US7682318B2 (en) | 2001-06-12 | 2010-03-23 | Pelikan Technologies, Inc. | Blood sampling apparatus and method |
US7041068B2 (en) | 2001-06-12 | 2006-05-09 | Pelikan Technologies, Inc. | Sampling module device and method |
AU2002315177A1 (en) | 2001-06-12 | 2002-12-23 | Pelikan Technologies, Inc. | Self optimizing lancing device with adaptation means to temporal variations in cutaneous properties |
US9795747B2 (en) | 2010-06-02 | 2017-10-24 | Sanofi-Aventis Deutschland Gmbh | Methods and apparatus for lancet actuation |
US7981056B2 (en) | 2002-04-19 | 2011-07-19 | Pelikan Technologies, Inc. | Methods and apparatus for lancet actuation |
JP4149911B2 (ja) | 2001-06-12 | 2008-09-17 | ペリカン テクノロジーズ インコーポレイテッド | 電気式ランセットアクチュエータ |
US9427532B2 (en) | 2001-06-12 | 2016-08-30 | Sanofi-Aventis Deutschland Gmbh | Tissue penetration device |
WO2002100254A2 (en) | 2001-06-12 | 2002-12-19 | Pelikan Technologies, Inc. | Method and apparatus for lancet launching device integrated onto a blood-sampling cartridge |
US9226699B2 (en) | 2002-04-19 | 2016-01-05 | Sanofi-Aventis Deutschland Gmbh | Body fluid sampling module with a continuous compression tissue interface surface |
US8337419B2 (en) | 2002-04-19 | 2012-12-25 | Sanofi-Aventis Deutschland Gmbh | Tissue penetration device |
DE60239132D1 (de) | 2001-06-12 | 2011-03-24 | Pelikan Technologies Inc | Gerät zur erhöhung der erfolgsrate im hinblick auf die durch einen fingerstich erhaltene blutausbeute |
US7344507B2 (en) | 2002-04-19 | 2008-03-18 | Pelikan Technologies, Inc. | Method and apparatus for lancet actuation |
EP2290358B1 (de) * | 2001-07-27 | 2015-11-11 | ARKRAY, Inc. | Analyseinstrument |
US8784335B2 (en) | 2002-04-19 | 2014-07-22 | Sanofi-Aventis Deutschland Gmbh | Body fluid sampling device with a capacitive sensor |
US7717863B2 (en) | 2002-04-19 | 2010-05-18 | Pelikan Technologies, Inc. | Method and apparatus for penetrating tissue |
US7547287B2 (en) | 2002-04-19 | 2009-06-16 | Pelikan Technologies, Inc. | Method and apparatus for penetrating tissue |
US7491178B2 (en) | 2002-04-19 | 2009-02-17 | Pelikan Technologies, Inc. | Method and apparatus for penetrating tissue |
US7291117B2 (en) | 2002-04-19 | 2007-11-06 | Pelikan Technologies, Inc. | Method and apparatus for penetrating tissue |
US8221334B2 (en) | 2002-04-19 | 2012-07-17 | Sanofi-Aventis Deutschland Gmbh | Method and apparatus for penetrating tissue |
US7331931B2 (en) | 2002-04-19 | 2008-02-19 | Pelikan Technologies, Inc. | Method and apparatus for penetrating tissue |
US8372016B2 (en) | 2002-04-19 | 2013-02-12 | Sanofi-Aventis Deutschland Gmbh | Method and apparatus for body fluid sampling and analyte sensing |
US7901362B2 (en) | 2002-04-19 | 2011-03-08 | Pelikan Technologies, Inc. | Method and apparatus for penetrating tissue |
US7909778B2 (en) | 2002-04-19 | 2011-03-22 | Pelikan Technologies, Inc. | Method and apparatus for penetrating tissue |
US7713214B2 (en) | 2002-04-19 | 2010-05-11 | Pelikan Technologies, Inc. | Method and apparatus for a multi-use body fluid sampling device with optical analyte sensing |
US9248267B2 (en) | 2002-04-19 | 2016-02-02 | Sanofi-Aventis Deustchland Gmbh | Tissue penetration device |
US7674232B2 (en) | 2002-04-19 | 2010-03-09 | Pelikan Technologies, Inc. | Method and apparatus for penetrating tissue |
US7976476B2 (en) | 2002-04-19 | 2011-07-12 | Pelikan Technologies, Inc. | Device and method for variable speed lancet |
US7232451B2 (en) | 2002-04-19 | 2007-06-19 | Pelikan Technologies, Inc. | Method and apparatus for penetrating tissue |
US8267870B2 (en) | 2002-04-19 | 2012-09-18 | Sanofi-Aventis Deutschland Gmbh | Method and apparatus for body fluid sampling with hybrid actuation |
US8579831B2 (en) | 2002-04-19 | 2013-11-12 | Sanofi-Aventis Deutschland Gmbh | Method and apparatus for penetrating tissue |
US7229458B2 (en) | 2002-04-19 | 2007-06-12 | Pelikan Technologies, Inc. | Method and apparatus for penetrating tissue |
US7371247B2 (en) | 2002-04-19 | 2008-05-13 | Pelikan Technologies, Inc | Method and apparatus for penetrating tissue |
US8702624B2 (en) | 2006-09-29 | 2014-04-22 | Sanofi-Aventis Deutschland Gmbh | Analyte measurement device with a single shot actuator |
US7648468B2 (en) | 2002-04-19 | 2010-01-19 | Pelikon Technologies, Inc. | Method and apparatus for penetrating tissue |
US9795334B2 (en) | 2002-04-19 | 2017-10-24 | Sanofi-Aventis Deutschland Gmbh | Method and apparatus for penetrating tissue |
US8360992B2 (en) | 2002-04-19 | 2013-01-29 | Sanofi-Aventis Deutschland Gmbh | Method and apparatus for penetrating tissue |
US9314194B2 (en) | 2002-04-19 | 2016-04-19 | Sanofi-Aventis Deutschland Gmbh | Tissue penetration device |
US7297122B2 (en) | 2002-04-19 | 2007-11-20 | Pelikan Technologies, Inc. | Method and apparatus for penetrating tissue |
US7892183B2 (en) | 2002-04-19 | 2011-02-22 | Pelikan Technologies, Inc. | Method and apparatus for body fluid sampling and analyte sensing |
US8574895B2 (en) | 2002-12-30 | 2013-11-05 | Sanofi-Aventis Deutschland Gmbh | Method and apparatus using optical techniques to measure analyte levels |
EP1628567B1 (de) | 2003-05-30 | 2010-08-04 | Pelikan Technologies Inc. | Verfahren und vorrichtung zur injektion von flüssigkeit |
US7850621B2 (en) | 2003-06-06 | 2010-12-14 | Pelikan Technologies, Inc. | Method and apparatus for body fluid sampling and analyte sensing |
WO2006001797A1 (en) | 2004-06-14 | 2006-01-05 | Pelikan Technologies, Inc. | Low pain penetrating |
WO2005020817A1 (en) * | 2003-09-01 | 2005-03-10 | Inverness Medical Switzerland Gmbh | Sampling device with capillary action |
US7682833B2 (en) * | 2003-09-10 | 2010-03-23 | Abbott Point Of Care Inc. | Immunoassay device with improved sample closure |
EP1671096A4 (de) | 2003-09-29 | 2009-09-16 | Pelikan Technologies Inc | Verfahren und apparatur für eine verbesserte probeneinfangvorrichtung |
US9351680B2 (en) | 2003-10-14 | 2016-05-31 | Sanofi-Aventis Deutschland Gmbh | Method and apparatus for a variable user interface |
US7822454B1 (en) | 2005-01-03 | 2010-10-26 | Pelikan Technologies, Inc. | Fluid sampling device with improved analyte detecting member configuration |
WO2005065414A2 (en) | 2003-12-31 | 2005-07-21 | Pelikan Technologies, Inc. | Method and apparatus for improving fluidic flow and sample capture |
US8828203B2 (en) | 2004-05-20 | 2014-09-09 | Sanofi-Aventis Deutschland Gmbh | Printable hydrogels for biosensors |
US9820684B2 (en) | 2004-06-03 | 2017-11-21 | Sanofi-Aventis Deutschland Gmbh | Method and apparatus for a fluid sampling device |
US9775553B2 (en) | 2004-06-03 | 2017-10-03 | Sanofi-Aventis Deutschland Gmbh | Method and apparatus for a fluid sampling device |
US8652831B2 (en) | 2004-12-30 | 2014-02-18 | Sanofi-Aventis Deutschland Gmbh | Method and apparatus for analyte measurement test time |
EP1705480B1 (de) * | 2005-03-22 | 2011-10-05 | Roche Diagnostics GmbH | Testelement zur Analyse von Körperflüssigkeiten |
JP2009521684A (ja) * | 2005-12-22 | 2009-06-04 | ハネウェル・インターナショナル・インコーポレーテッド | 携帯用サンプル分析装置のカートリッジ |
US9134286B2 (en) | 2007-10-30 | 2015-09-15 | Panasonic Healthcare Co., Ltd. | Analyzing device, analyzing apparatus using the device, and analyzing method |
US9386944B2 (en) | 2008-04-11 | 2016-07-12 | Sanofi-Aventis Deutschland Gmbh | Method and apparatus for analyte detecting device |
US9375169B2 (en) | 2009-01-30 | 2016-06-28 | Sanofi-Aventis Deutschland Gmbh | Cam drive for managing disposable penetrating member actions with a single motor and motor and control system |
JP4674283B2 (ja) * | 2009-06-01 | 2011-04-20 | アークレイ株式会社 | 分析用具およびその製造方法 |
KR101104391B1 (ko) * | 2009-06-30 | 2012-01-16 | 주식회사 세라젬메디시스 | 검출기와 함께 사용되어 생체물질을 측정하는 센서 및 이를 이용하는 장치 |
US8357276B2 (en) * | 2009-08-31 | 2013-01-22 | Abbott Diabetes Care Inc. | Small volume test strips with large sample fill ports, supported test strips, and methods of making and using same |
US8965476B2 (en) | 2010-04-16 | 2015-02-24 | Sanofi-Aventis Deutschland Gmbh | Tissue penetration device |
US11430279B2 (en) * | 2012-05-09 | 2022-08-30 | Wisconsin Alumni Research Foundation | Functionalized microfluidic device and method |
US9523653B2 (en) | 2013-05-09 | 2016-12-20 | Changsha Sinocare Inc. | Disposable test sensor with improved sampling entrance |
US9518951B2 (en) | 2013-12-06 | 2016-12-13 | Changsha Sinocare Inc. | Disposable test sensor with improved sampling entrance |
US9897566B2 (en) | 2014-01-13 | 2018-02-20 | Changsha Sinocare Inc. | Disposable test sensor |
US9939401B2 (en) | 2014-02-20 | 2018-04-10 | Changsha Sinocare Inc. | Test sensor with multiple sampling routes |
CN109313156B (zh) * | 2016-06-17 | 2021-04-20 | 豪夫迈·罗氏有限公司 | 用于分析体液样本的测试*** |
JP6938149B2 (ja) * | 2016-12-22 | 2021-09-22 | リンテック株式会社 | 検査用カバーフィルム、検査部材、および検査部材の製造方法 |
JP6966860B2 (ja) * | 2017-04-07 | 2021-11-17 | リンテック株式会社 | 検査用カバーフィルム、検査部材、および検査用カバーフィルムの製造方法 |
Family Cites Families (45)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS57208997A (en) * | 1981-06-17 | 1982-12-22 | Fuji Photo Film Co Ltd | Liquid analyzing material for oxidase enzyme reaction system |
US4790640A (en) * | 1985-10-11 | 1988-12-13 | Nason Frederic L | Laboratory slide |
US4849340A (en) * | 1987-04-03 | 1989-07-18 | Cardiovascular Diagnostics, Inc. | Reaction system element and method for performing prothrombin time assay |
JP2696708B2 (ja) | 1988-09-30 | 1998-01-14 | 株式会社アドバンス | 自動採血装置 |
US5066465A (en) * | 1989-12-27 | 1991-11-19 | Olympus Optical Co., Ltd. | Reaction apparatus |
JP3382632B2 (ja) | 1992-03-13 | 2003-03-04 | オリンパス光学工業株式会社 | 生体関連物質の測定方法およびそれに用いる反応容器 |
JP3149597B2 (ja) | 1993-02-03 | 2001-03-26 | 松下電器産業株式会社 | 体液成分測定装置 |
JPH0755795A (ja) | 1993-08-18 | 1995-03-03 | Kanebo Ltd | 分析用試験片 |
JPH0755793A (ja) | 1993-08-18 | 1995-03-03 | Kanebo Ltd | 分析用試験片 |
JP3027306B2 (ja) | 1994-06-02 | 2000-04-04 | 松下電器産業株式会社 | バイオセンサおよびその製造方法 |
FR2744607B1 (fr) | 1996-02-12 | 1998-04-30 | Lvmh Rech | Brosse perfectionnee pour le maquillage des cils de l'oeil |
JP3621502B2 (ja) | 1996-04-02 | 2005-02-16 | アプルス株式会社 | ランセットアッセンブリ |
US6001307A (en) * | 1996-04-26 | 1999-12-14 | Kyoto Daiichi Kagaku Co., Ltd. | Device for analyzing a sample |
ES2121564B1 (es) * | 1996-05-17 | 2001-02-01 | Mercury Diagnostics Inc | Metodos y aparatos para extraer fluido corporal desde una incision. |
US5879311A (en) * | 1996-05-17 | 1999-03-09 | Mercury Diagnostics, Inc. | Body fluid sampling device and methods of use |
US5951492A (en) * | 1996-05-17 | 1999-09-14 | Mercury Diagnostics, Inc. | Methods and apparatus for sampling and analyzing body fluid |
EP1579814A3 (de) * | 1996-05-17 | 2006-06-14 | Roche Diagnostics Operations, Inc. | Verfahren und Vorrichtung zur Probenahme und Analyse von Körperflüssigkeit |
US5951493A (en) * | 1997-05-16 | 1999-09-14 | Mercury Diagnostics, Inc. | Methods and apparatus for expressing body fluid from an incision |
US6332871B1 (en) * | 1996-05-17 | 2001-12-25 | Amira Medical | Blood and interstitial fluid sampling device |
US6015392A (en) * | 1996-05-17 | 2000-01-18 | Mercury Diagnostics, Inc. | Apparatus for sampling body fluid |
WO1998019159A1 (en) * | 1996-10-30 | 1998-05-07 | Mercury Diagnostics, Inc. | Synchronized analyte testing system |
US6093156A (en) * | 1996-12-06 | 2000-07-25 | Abbott Laboratories | Method and apparatus for obtaining blood for diagnostic tests |
AT404992B (de) * | 1997-04-17 | 1999-04-26 | Avl List Gmbh | Sensor zur bestimmung eines enzymsubstrates |
US5759364A (en) * | 1997-05-02 | 1998-06-02 | Bayer Corporation | Electrochemical biosensor |
US5948695A (en) * | 1997-06-17 | 1999-09-07 | Mercury Diagnostics, Inc. | Device for determination of an analyte in a body fluid |
DE19753848A1 (de) * | 1997-12-04 | 1999-06-10 | Roche Diagnostics Gmbh | Modifikation von Oberflächen zur Steigerung der Oberflächenspannung |
DE19753847A1 (de) * | 1997-12-04 | 1999-06-10 | Roche Diagnostics Gmbh | Analytisches Testelement mit Kapillarkanal |
DE19753850A1 (de) * | 1997-12-04 | 1999-06-10 | Roche Diagnostics Gmbh | Probennahmevorrichtung |
US5997817A (en) | 1997-12-05 | 1999-12-07 | Roche Diagnostics Corporation | Electrochemical biosensor test strip |
JP3896435B2 (ja) | 1997-12-17 | 2007-03-22 | アークレイ株式会社 | センサおよびセンサ集合体 |
US5975153A (en) * | 1998-02-13 | 1999-11-02 | Roche Diagnostics Corporation | Capillary fill test device with improved fluid delivery |
JP3382853B2 (ja) * | 1998-04-09 | 2003-03-04 | 松下電器産業株式会社 | 体液検査装置 |
JPH11304748A (ja) | 1998-04-23 | 1999-11-05 | Omron Corp | バイオセンサ |
WO2000040150A1 (en) * | 1999-01-04 | 2000-07-13 | Terumo Kabushiki Kaisha | Assembly having lancet and means for collecting and detecting body fluid |
JP4352109B2 (ja) | 1999-01-29 | 2009-10-28 | アークレイ株式会社 | バイオセンサ |
JP2000258382A (ja) * | 1999-03-05 | 2000-09-22 | Arkray Inc | 検体少量型バイオセンサ |
US6767440B1 (en) * | 2001-04-24 | 2004-07-27 | Roche Diagnostics Corporation | Biosensor |
US6662439B1 (en) * | 1999-10-04 | 2003-12-16 | Roche Diagnostics Corporation | Laser defined features for patterned laminates and electrodes |
JP2001159618A (ja) | 1999-12-03 | 2001-06-12 | Matsushita Electric Ind Co Ltd | バイオセンサ |
US6571651B1 (en) * | 2000-03-27 | 2003-06-03 | Lifescan, Inc. | Method of preventing short sampling of a capillary or wicking fill device |
US6488828B1 (en) | 2000-07-20 | 2002-12-03 | Roche Diagnostics Corporation | Recloseable biosensor |
US6540890B1 (en) * | 2000-11-01 | 2003-04-01 | Roche Diagnostics Corporation | Biosensor |
US6447657B1 (en) * | 2000-12-04 | 2002-09-10 | Roche Diagnostics Corporation | Biosensor |
JP4736323B2 (ja) * | 2001-07-13 | 2011-07-27 | アークレイ株式会社 | 分析用具を備えた濃度測定装置用の穿刺要素一体装着体、および体液採取用具 |
EP2290358B1 (de) * | 2001-07-27 | 2015-11-11 | ARKRAY, Inc. | Analyseinstrument |
-
2002
- 2002-07-26 EP EP10193213.5A patent/EP2290358B1/de not_active Expired - Lifetime
- 2002-07-26 CN CNB028147049A patent/CN1300578C/zh not_active Expired - Lifetime
- 2002-07-26 DE DE10193213T patent/DE10193213T8/de active Active
- 2002-07-26 EP EP02749377.4A patent/EP1413880B1/de not_active Expired - Lifetime
- 2002-07-26 JP JP2003515851A patent/JP4282477B2/ja not_active Expired - Lifetime
- 2002-07-26 US US10/484,955 patent/US7824616B2/en not_active Expired - Fee Related
- 2002-07-26 WO PCT/JP2002/007654 patent/WO2003010530A1/ja active Application Filing
-
2010
- 2010-10-12 US US12/902,647 patent/US8425841B2/en not_active Expired - Lifetime
Also Published As
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---|---|
US8425841B2 (en) | 2013-04-23 |
CN1300578C (zh) | 2007-02-14 |
CN1535377A (zh) | 2004-10-06 |
EP1413880A4 (de) | 2010-06-02 |
JPWO2003010530A1 (ja) | 2004-11-18 |
EP1413880A1 (de) | 2004-04-28 |
EP2290358A2 (de) | 2011-03-02 |
DE10193213T8 (de) | 2013-04-25 |
EP2290358A3 (de) | 2012-02-29 |
US20040197231A1 (en) | 2004-10-07 |
US20110060203A1 (en) | 2011-03-10 |
EP2290358B1 (de) | 2015-11-11 |
JP4282477B2 (ja) | 2009-06-24 |
WO2003010530A1 (fr) | 2003-02-06 |
EP1413880B1 (de) | 2015-09-02 |
US7824616B2 (en) | 2010-11-02 |
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