DD252605A1 - Verfahren zur herstellung von carbapenem-antibiotika - Google Patents

Verfahren zur herstellung von carbapenem-antibiotika

Info

Publication number: DD252605A1
Authority: DD; German Democratic Republic
Prior art keywords: preparation; carbapenem antibiotics; carbapenem; antibiotics
Prior art date: 1985-09-11

Application number

DD86294267A

Other languages

English (en)

Inventor

Alain Martel

Carol Bachand

Original Assignee

Bristol Myers Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-09-11

Filing date

1986-09-09

Publication date

1987-12-23

1986-09-09 Application filed by Bristol Myers Co filed Critical Bristol Myers Co

1987-12-23 Publication of DD252605A1 publication Critical patent/DD252605A1/de

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
- C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
- C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
- C07D477/16—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
- C07D477/20—Sulfur atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Communicable Diseases (AREA)
Pharmacology & Pharmacy (AREA)
Oncology (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

DD86294267A 1985-09-11 1986-09-09 Verfahren zur herstellung von carbapenem-antibiotika DD252605A1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US06/774,628 US4665169A (en)	1985-09-11	1985-09-11	Carbapenem antibiotics

Publications (1)

Publication Number	Publication Date
DD252605A1 true DD252605A1 (de)	1987-12-23

Family

ID=25101800

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DD86294267A DD252605A1 (de)	1985-09-11	1986-09-09	Verfahren zur herstellung von carbapenem-antibiotika

Country Status (31)

Country	Link
US (1)	US4665169A (de)
JP (1)	JPS6261980A (de)
KR (1)	KR910006807B1 (de)
CN (1)	CN1015261B (de)
AR (1)	AR242577A1 (de)
AT (1)	AT396472B (de)
AU (1)	AU596990B2 (de)
BE (1)	BE905415A (de)
CH (1)	CH669381A5 (de)
CS (1)	CS259892B2 (de)
DD (1)	DD252605A1 (de)
DE (1)	DE3630857C2 (de)
DK (1)	DK433586A (de)
ES (1)	ES2002303A6 (de)
FI (1)	FI81803C (de)
FR (1)	FR2587704B1 (de)
GB (1)	GB2180238B (de)
GR (1)	GR862313B (de)
HU (1)	HU198491B (de)
IL (1)	IL79969A0 (de)
IT (1)	IT1207578B (de)
LU (1)	LU86575A1 (de)
MY (1)	MY102957A (de)
NL (1)	NL8602282A (de)
NZ (1)	NZ217519A (de)
PT (1)	PT83361B (de)
SE (1)	SE469630B (de)
SU (1)	SU1480764A3 (de)
YU (1)	YU45800B (de)
ZA (1)	ZA866638B (de)
ZW (1)	ZW16186A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5321020A (en) *	1989-03-28	1994-06-14	Pfizer Inc.	Antibacterial 2-carbapenem derivatives
HUT63167A (en) *	1989-03-28	1993-07-28	Pfizer	Process for producing antibacterial 2-carbapenem derivatives and pharmaceutical compositions comprising same as active ingredient
US5602118A (en) *	1993-03-16	1997-02-11	American Cyanamid Company	2-thiosubstituted carbapenems
RU2714730C1 (ru)	2019-04-11	2020-02-19	Общество с ограниченной ответственностью "КС-ТЕХНОЛОГИИ"	Конусная инерционная дробилка с опорным подшипником скольжения

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3950357A (en) *	1974-11-25	1976-04-13	Merck & Co., Inc.	Antibiotics
US4235920A (en) *	1975-11-21	1980-11-25	Merck & Co., Inc.	N-Alkylated derivatives of thienamycin
AU531084B2 (en) *	1977-10-19	1983-08-11	Merck & Co., Inc.	Azetidine derivatives
AU4061378A (en) *	1977-10-19	1980-04-17	Merck & Co., Inc.	1-azabicyclo (3.2.0) hept-2-enes
US4232036A (en) *	1978-10-24	1980-11-04	Merck & Co., Inc.	6-, 1- and 2-Substituted-1-carbadethiapen-2-em-3-carboxylic acids
DE2966497D1 (en) *	1978-10-24	1984-01-26	Merck & Co Inc	6-, 1- and 2-substituted-1-carbapen-2-em-3-carboxylic acids, processes for the preparation of such compounds and pharmaceutical composition comprising such compounds
DK165280A (da) *	1979-04-19	1980-10-20	Merck & Co Inc	Fremgangsmaade til fremstilling af 2- og 6-substituerede 1-carbadethiapen-2-em-3-carboxylsyrer og mellemprodukter til brug ved udoevelse af fremgangsmaaden
US4376774A (en) *	1979-05-29	1983-03-15	Merck & Co., Inc.	Antibiotic N-heterocyclyl thienamycin
IE52147B1 (en) *	1980-03-27	1987-07-08	Merck & Co Inc	4-(3-carboxy-2-oxopropyl)-azetidin-2-ones and process for their preparation
EP0037082B1 (de) *	1980-03-27	1985-03-20	Merck & Co. Inc.	Verfahren zur Herstellung von 1-Carbapenem-Derivaten und von Zwischenprodukten via silyl-substituierter Dithioacetale
US4309346A (en) *	1980-03-27	1982-01-05	Merck & Co., Inc.	Process for the preparation of 1-carbapenems and intermediates via trithioorthoacetates
EP0038869A1 (de) *	1980-04-30	1981-11-04	Merck & Co. Inc.	Verfahren zur Herstellung von 1-Carbapenemen und Zwischenprodukte für ihre Herstellung
JPS56161393A (en) *	1980-05-16	1981-12-11	Sanraku Inc	Beta-lactam compound
CA1198440A (en) *	1982-04-08	1985-12-24	Choung U. Kim	Carbapenem antibiotics
US4552696A (en) *	1982-04-09	1985-11-12	Bristol-Myers Company	Carbapenem antibiotics
US4536335A (en) *	1982-06-18	1985-08-20	Bristol-Myers Company	Carbapenem antibiotics
FI832619A (fi) *	1982-07-26	1984-01-27	Sandoz Ag	Fluoralkylerade karbapenemderivat
NZ205626A (en) *	1982-09-28	1986-12-05	Bristol Myers Co	Carbapenem antibiotics
DK140584A (da) *	1983-03-08	1984-09-09	Bristol Myers Co	Fremgangsmaade til fremstilling af carbapenemderivater
JPS60202886A (ja) *	1984-03-27	1985-10-14	Sankyo Co Ltd	１―置換カルバペネム―３―カルボン酸誘導体

1985
- 1985-09-11 US US06/774,628 patent/US4665169A/en not_active Expired - Fee Related
1986
- 1986-08-08 ZW ZW161/86A patent/ZW16186A1/xx unknown
- 1986-08-29 AR AR86305095A patent/AR242577A1/es active
- 1986-09-02 ZA ZA866638A patent/ZA866638B/xx unknown
- 1986-09-04 AU AU62348/86A patent/AU596990B2/en not_active Ceased
- 1986-09-08 IL IL79969A patent/IL79969A0/xx not_active IP Right Cessation
- 1986-09-08 FI FI863609A patent/FI81803C/fi not_active IP Right Cessation
- 1986-09-08 FR FR868612540A patent/FR2587704B1/fr not_active Expired
- 1986-09-09 DD DD86294267A patent/DD252605A1/de not_active IP Right Cessation
- 1986-09-09 NZ NZ217519A patent/NZ217519A/xx unknown
- 1986-09-09 CN CN86105933A patent/CN1015261B/zh not_active Expired
- 1986-09-10 NL NL8602282A patent/NL8602282A/nl not_active Application Discontinuation
- 1986-09-10 BE BE0/217150A patent/BE905415A/fr not_active IP Right Cessation
- 1986-09-10 ES ES8601760A patent/ES2002303A6/es not_active Expired
- 1986-09-10 JP JP61213707A patent/JPS6261980A/ja active Pending
- 1986-09-10 DK DK433586A patent/DK433586A/da not_active Application Discontinuation
- 1986-09-10 GB GB8621759A patent/GB2180238B/en not_active Expired
- 1986-09-10 IT IT8621666A patent/IT1207578B/it active
- 1986-09-10 DE DE3630857A patent/DE3630857C2/de not_active Expired - Fee Related
- 1986-09-10 CH CH3640/86A patent/CH669381A5/de not_active IP Right Cessation
- 1986-09-10 GR GR862313A patent/GR862313B/el unknown
- 1986-09-10 SE SE8603798A patent/SE469630B/sv not_active IP Right Cessation
- 1986-09-10 SU SU864028122A patent/SU1480764A3/ru active
- 1986-09-10 KR KR1019860007583A patent/KR910006807B1/ko not_active IP Right Cessation
- 1986-09-10 LU LU86575A patent/LU86575A1/fr unknown
- 1986-09-11 YU YU158586A patent/YU45800B/sh unknown
- 1986-09-11 AT AT0245286A patent/AT396472B/de not_active IP Right Cessation
- 1986-09-11 CS CS866567A patent/CS259892B2/cs unknown
- 1986-09-11 HU HU863916A patent/HU198491B/hu not_active IP Right Cessation
- 1986-09-11 PT PT83361A patent/PT83361B/pt not_active IP Right Cessation
1987
- 1987-10-01 MY MYPI87002710A patent/MY102957A/en unknown

Also Published As

Publication number	Publication date
US4665169A (en)	1987-05-12
NL8602282A (nl)	1987-04-01
GB2180238B (en)	1989-09-06
HUT42487A (en)	1987-07-28
NZ217519A (en)	1990-07-26
FI81803B (fi)	1990-08-31
DE3630857C2 (de)	1994-04-07
CN1015261B (zh)	1992-01-01
GR862313B (en)	1987-01-12
IT1207578B (it)	1989-05-25
YU45800B (sh)	1992-07-20
KR870003110A (ko)	1987-04-15
AU596990B2 (en)	1990-05-24
SE8603798D0 (sv)	1986-09-10
AU6234886A (en)	1987-03-12
CS656786A2 (en)	1988-03-15
ES2002303A6 (es)	1988-08-01
HU198491B (en)	1989-10-30
PT83361A (en)	1986-10-01
YU158586A (en)	1988-02-29
FI863609A0 (fi)	1986-09-08
GB8621759D0 (en)	1986-10-15
FI863609A (fi)	1987-03-12
AR242577A1 (es)	1993-04-30
ZW16186A1 (en)	1988-03-30
CS259892B2 (en)	1988-11-15
ZA866638B (en)	1987-05-27
CH669381A5 (de)	1989-03-15
IT8621666A0 (it)	1986-09-10
AT396472B (de)	1993-09-27
SE469630B (sv)	1993-08-09
KR910006807B1 (ko)	1991-09-02
FI81803C (fi)	1990-12-10
IL79969A0 (en)	1986-12-31
JPS6261980A (ja)	1987-03-18
CN86105933A (zh)	1987-05-20
PT83361B (pt)	1989-05-12
DE3630857A1 (de)	1987-03-19
FR2587704A1 (fr)	1987-03-27
DK433586A (da)	1987-03-12
BE905415A (fr)	1987-03-10
DK433586D0 (da)	1986-09-10
SU1480764A3 (ru)	1989-05-15
SE8603798L (sv)	1987-03-12
ATA245286A (de)	1993-01-15
GB2180238A (en)	1987-03-25
LU86575A1 (fr)	1987-04-02
MY102957A (en)	1993-03-31
FR2587704B1 (fr)	1989-02-24

Legal Events

Date	Code	Title	Description
1999-02-04	ENJ	Ceased due to non-payment of renewal fee

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