CY2018002I1 - Εγκαρσια συνδεδεμενα πολυμερη εναλλαγης κατιοντος, συνθεσεις και χρηση στη θεραπεια υπερκαλιαιμιας - Google Patents
Εγκαρσια συνδεδεμενα πολυμερη εναλλαγης κατιοντος, συνθεσεις και χρηση στη θεραπεια υπερκαλιαιμιαςInfo
- Publication number
- CY2018002I1 CY2018002I1 CY2018002C CY2018002C CY2018002I1 CY 2018002 I1 CY2018002 I1 CY 2018002I1 CY 2018002 C CY2018002 C CY 2018002C CY 2018002 C CY2018002 C CY 2018002C CY 2018002 I1 CY2018002 I1 CY 2018002I1
- Authority
- CY
- Cyprus
- Prior art keywords
- hyperkalasemia
- compositions
- treatment
- cross
- cation exchange
- Prior art date
Links
- 238000005341 cation exchange Methods 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 229920000642 polymer Polymers 0.000 title 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7004—Monosaccharides having only carbon, hydrogen and oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/047—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates having two or more hydroxy groups, e.g. sorbitol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
- A61K31/765—Polymers containing oxygen
- A61K31/78—Polymers containing oxygen of acrylic acid or derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/08—Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J39/00—Cation exchange; Use of material as cation exchangers; Treatment of material for improving the cation exchange properties
- B01J39/08—Use of material as cation exchangers; Treatment of material for improving the cation exchange properties
- B01J39/16—Organic material
- B01J39/18—Macromolecular compounds
- B01J39/20—Macromolecular compounds obtained by reactions only involving unsaturated carbon-to-carbon bonds
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F220/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
- C08F220/02—Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
- C08F220/10—Esters
- C08F220/22—Esters containing halogen
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F212/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by an aromatic carbocyclic ring
- C08F212/34—Monomers containing two or more unsaturated aliphatic radicals
- C08F212/36—Divinylbenzene
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Polymers & Plastics (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Molecular Biology (AREA)
- Obesity (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Heart & Thoracic Surgery (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Biochemistry (AREA)
- Vascular Medicine (AREA)
- Nutrition Science (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Processes Of Treating Macromolecular Substances (AREA)
Applications Claiming Priority (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US9109708P | 2008-08-22 | 2008-08-22 | |
US9111008P | 2008-08-22 | 2008-08-22 | |
US9112508P | 2008-08-22 | 2008-08-22 | |
US16589409P | 2009-04-01 | 2009-04-01 | |
US16589909P | 2009-04-01 | 2009-04-01 | |
US16590509P | 2009-04-02 | 2009-04-02 | |
PCT/US2009/054706 WO2010022383A2 (en) | 2008-08-22 | 2009-08-22 | Crosslinked cation exchange polymers, compositions and use in treating hyperkalemia |
Publications (1)
Publication Number | Publication Date |
---|---|
CY2018002I1 true CY2018002I1 (el) | 2019-07-10 |
Family
ID=41707686
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY2018002C CY2018002I1 (el) | 2008-08-22 | 2018-01-15 | Εγκαρσια συνδεδεμενα πολυμερη εναλλαγης κατιοντος, συνθεσεις και χρηση στη θεραπεια υπερκαλιαιμιας |
CY20181101268T CY1120930T1 (el) | 2008-08-22 | 2018-11-29 | Εγκαρσια συνδεδεμενα πολυμερη ανταλλαγης κατιοντος, συνθεσεις και χρηση στη θεραπεια υπερκαλιαιμιας |
CY2019002C CY2019002I2 (el) | 2008-08-22 | 2019-01-09 | Εγκαρσια συνδεδεμενα πολυμερη ανταλλαγης κατιοντος, συνθεσεις και χρηση στη θεραπεια υπερκαλιαιμιας |
Family Applications After (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY20181101268T CY1120930T1 (el) | 2008-08-22 | 2018-11-29 | Εγκαρσια συνδεδεμενα πολυμερη ανταλλαγης κατιοντος, συνθεσεις και χρηση στη θεραπεια υπερκαλιαιμιας |
CY2019002C CY2019002I2 (el) | 2008-08-22 | 2019-01-09 | Εγκαρσια συνδεδεμενα πολυμερη ανταλλαγης κατιοντος, συνθεσεις και χρηση στη θεραπεια υπερκαλιαιμιας |
Country Status (27)
Country | Link |
---|---|
US (4) | US20110236340A1 (el) |
EP (4) | EP3431094B1 (el) |
JP (7) | JP5756403B2 (el) |
KR (5) | KR102150184B1 (el) |
CN (2) | CN103919792B (el) |
AU (1) | AU2009282721B2 (el) |
BR (1) | BRPI0917853C1 (el) |
CA (1) | CA2735058C (el) |
CY (3) | CY2018002I1 (el) |
DE (1) | DE112009002063T5 (el) |
DK (3) | DK2365988T4 (el) |
ES (3) | ES2545887T5 (el) |
FI (1) | FI3431094T3 (el) |
GB (4) | GB2475657B (el) |
HK (1) | HK1184675A1 (el) |
HR (3) | HRP20230091T1 (el) |
HU (3) | HUE061320T2 (el) |
LT (4) | LT2957286T (el) |
LU (1) | LUC00094I2 (el) |
MX (2) | MX364398B (el) |
NL (1) | NL300962I2 (el) |
NO (2) | NO2018004I1 (el) |
PL (3) | PL2365988T5 (el) |
PT (3) | PT3431094T (el) |
SI (2) | SI3431094T1 (el) |
SM (1) | SMT201500207T1 (el) |
WO (1) | WO2010022383A2 (el) |
Families Citing this family (23)
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WO2010022380A2 (en) | 2008-08-22 | 2010-02-25 | Relypsa, Inc. | Linear polyol stabilized polyfluoroacrylate compositions |
ES2545887T5 (es) | 2008-08-22 | 2020-02-17 | Vifor Int Ltd | Polímeros reticulados de intercambio catiónico, composiciones y uso en el tratamiento de la hiperpotasemia |
ES2670580T3 (es) * | 2010-03-20 | 2018-05-31 | Relypsa, Inc. | Procedimiento continuo para preparar partículas de polifluoroacrilato |
EP2673237B1 (en) | 2011-02-11 | 2018-11-07 | ZS Pharma, Inc | Use of a zirconium silicate for the treatment of hyperkalemia |
CN110028603A (zh) | 2011-06-27 | 2019-07-19 | 瑞立普萨公司 | 用于将聚合酯转化为聚合酸的方法 |
ES2758708T3 (es) | 2011-06-27 | 2020-05-06 | Relypsa Inc | Fluoración de ésteres de acrilato y derivados |
CA2879425A1 (en) * | 2012-07-19 | 2014-01-23 | Relypsa, Inc. | Compositions comprising crosslinked cation-binding polymers |
US9982940B2 (en) | 2012-08-09 | 2018-05-29 | Patheon Austria Gmbh & Co Kg | Process for drying polymeric materials |
EP2916851A2 (en) * | 2012-10-08 | 2015-09-16 | Relypsa, Inc. | Potassium-binding agents for treating hypertension and hyperkalemia |
US10695365B2 (en) | 2012-10-22 | 2020-06-30 | ZS Pharma, Inc. | Microporous zirconium silicate for the treatment of hyperkalemia |
JP6280636B2 (ja) | 2013-04-05 | 2018-02-14 | ズィーエス・ファーマ,インコーポレーテッド | カリウムの低減と慢性腎臓病及び/または慢性心臓病の治療のための微多孔性ケイ酸ジルコニウム及び利尿剤 |
MX2017007603A (es) * | 2014-12-23 | 2017-10-19 | Ardelyx Inc | Composiciones y metodos para tratar hiperpotasemia. |
WO2017040520A1 (en) | 2015-08-31 | 2017-03-09 | Hitachi Chemical Co., Ltd. | Molecular methods for assessing urothelial disease |
US9592253B1 (en) | 2015-10-14 | 2017-03-14 | ZS Pharma, Inc. | Extended use zirconium silicate compositions and methods of use thereof |
ITUB20159278A1 (it) | 2015-12-23 | 2017-06-23 | Rjw Pharma Llc | Procedimento per la sintesi di patiromer |
WO2019220450A1 (en) | 2018-05-16 | 2019-11-21 | Solara Active Pharma Sciences Limited | Process for preparation of patiromer |
MX2021011044A (es) * | 2019-03-13 | 2021-10-13 | Astrazeneca Ab | Agentes de union a potasio para su uso en pacientes de hemodialisis. |
CN114867710A (zh) * | 2019-11-14 | 2022-08-05 | 维福(国际)有限公司 | 2-氟代丙烯酸烷基酯的一步合成 |
CN116323717A (zh) * | 2021-09-13 | 2023-06-23 | 中美华世通生物医药科技(武汉)股份有限公司 | 治疗高钾血症的聚合物药物及其制备方法 |
US20240139234A1 (en) * | 2021-11-17 | 2024-05-02 | Waterstone Pharmaceuticals (Wuhan) Co., Ltd. | Pharmaceutical polymer for treating hyperkalemia and preparation method thereof |
CN114369729B (zh) * | 2021-12-28 | 2023-11-03 | 江苏容汇通用锂业股份有限公司 | 一种利用锂矿渣进行浸出液除钾的工艺 |
CN114394918B (zh) * | 2022-01-19 | 2023-10-20 | 罗长青 | 一种2-[[三(羟甲基)甲基]氨基]乙磺酸的制备方法 |
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