CY1110713T1 - Ερυθροποιητινη σε υποπολυκυτταραιμικες δοσεις για τη θεραπεια του διαβητη - Google Patents

Ερυθροποιητινη σε υποπολυκυτταραιμικες δοσεις για τη θεραπεια του διαβητη

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Publication number
CY1110713T1
CY1110713T1 CY20101100712T CY101100712T CY1110713T1 CY 1110713 T1 CY1110713 T1 CY 1110713T1 CY 20101100712 T CY20101100712 T CY 20101100712T CY 101100712 T CY101100712 T CY 101100712T CY 1110713 T1 CY1110713 T1 CY 1110713T1
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CY
Cyprus
Prior art keywords
epo
tissue
endothelial
derivatives
stimulating
Prior art date
Application number
CY20101100712T
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English (en)
Inventor
Ferdinand Hermann Dr Bahlmann
Hermann Prof Dr Haller
Original Assignee
Epoplus Gmbh & Co. Kg
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Publication date
Application filed by Epoplus Gmbh & Co. Kg filed Critical Epoplus Gmbh & Co. Kg
Publication of CY1110713T1 publication Critical patent/CY1110713T1/el

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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18Growth factors; Growth regulators
    • A61K38/1858Platelet-derived growth factor [PDGF]
    • A61K38/1866Vascular endothelial growth factor [VEGF]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18Growth factors; Growth regulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18Growth factors; Growth regulators
    • A61K38/1816Erythropoietin [EPO]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18Growth factors; Growth regulators
    • A61K38/1891Angiogenesic factors; Angiogenin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • A61K38/193Colony stimulating factors [CSF]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
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    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
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    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
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    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
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    • A61P9/00Drugs for disorders of the cardiovascular system
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    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
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    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
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    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/14Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers

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  • Health & Medical Sciences (AREA)
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  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
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  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Dermatology (AREA)
  • Urology & Nephrology (AREA)
  • Reproductive Health (AREA)
  • Emergency Medicine (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Pulmonology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

Η παρούσα εφεύρεση αφορά τη χρήση ερυθροποιητίνης για τη διέγερση της φυσιολογικής κινητοποίησης, του πολλαπλασιασμού και της διαφοροποίησης πρόδρομων ενδοθηλιακών κυττάρων, για τη διέγερση της νεοαγγειογένεσης, για τη θεραπεία νόσων, οι οποίες σχετίζονται με μια δυσλειτουργία των πρόδρομων ενδοθηλιακών κυττάρων και για την παραγωγή φαρμακευτικών συνθέσεων για τη θεραπεία τέτοιου είδους νόσων, καθώς και φαρμακευτικών συνθέσεων, οι οποίες περιλαμβάνουν ερυθροποιητίνη και άλλες δραστικές ουσίες, κατάλληλες για τη διέγερση πρόδρομων ενδοθηλιακών κυττάρων.
CY20101100712T 2002-07-26 2010-07-29 Ερυθροποιητινη σε υποπολυκυτταραιμικες δοσεις για τη θεραπεια του διαβητη CY1110713T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10234192A DE10234192B4 (de) 2002-07-26 2002-07-26 Verwendung von Erythropoetin
EP07001689A EP1779862B1 (de) 2002-07-26 2003-07-25 Erythropoietin in subpolycythämischen dosen zur behandlung von diabetes

Publications (1)

Publication Number Publication Date
CY1110713T1 true CY1110713T1 (el) 2015-06-10

Family

ID=30128436

Family Applications (2)

Application Number Title Priority Date Filing Date
CY20071100871T CY1108052T1 (el) 2002-07-26 2007-07-02 Ερυθροποιητiνη σε υποπολυκυτταραιμικeς δoσεις
CY20101100712T CY1110713T1 (el) 2002-07-26 2010-07-29 Ερυθροποιητινη σε υποπολυκυτταραιμικες δοσεις για τη θεραπεια του διαβητη

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CY20071100871T CY1108052T1 (el) 2002-07-26 2007-07-02 Ερυθροποιητiνη σε υποπολυκυτταραιμικeς δoσεις

Country Status (27)

Country Link
US (4) US7745387B2 (el)
EP (3) EP2191838A1 (el)
JP (4) JP4727988B2 (el)
KR (2) KR20050026513A (el)
CN (3) CN101099731B (el)
AT (2) ATE468132T1 (el)
AU (2) AU2003255290B2 (el)
BR (1) BR0312981A (el)
CA (2) CA2493598A1 (el)
CY (2) CY1108052T1 (el)
DE (3) DE10234192B4 (el)
DK (2) DK1526867T3 (el)
EA (3) EA013966B1 (el)
ES (2) ES2285195T3 (el)
HK (2) HK1081841A1 (el)
HR (3) HRP20050065A2 (el)
IL (2) IL166401A0 (el)
IS (3) IS2671B (el)
MX (1) MXPA05001120A (el)
NO (1) NO20051002L (el)
PL (2) PL374874A1 (el)
PT (2) PT1526867E (el)
SG (1) SG177004A1 (el)
SI (2) SI1526867T1 (el)
UA (2) UA94913C2 (el)
WO (1) WO2004012759A2 (el)
ZA (1) ZA200500726B (el)

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