CY1110495T1 - Χρηση ενος αγωνιστη υποδοχεα nmda για τη θεραπεια εμβοης που προκαλειται απο κοχλιακη διεγερτοτοξικοτητα - Google Patents

Χρηση ενος αγωνιστη υποδοχεα nmda για τη θεραπεια εμβοης που προκαλειται απο κοχλιακη διεγερτοτοξικοτητα

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Publication number
CY1110495T1
CY1110495T1 CY20091100944T CY091100944T CY1110495T1 CY 1110495 T1 CY1110495 T1 CY 1110495T1 CY 20091100944 T CY20091100944 T CY 20091100944T CY 091100944 T CY091100944 T CY 091100944T CY 1110495 T1 CY1110495 T1 CY 1110495T1
Authority
CY
Cyprus
Prior art keywords
receptor
cog
caused
treatment
nmda receptor
Prior art date
Application number
CY20091100944T
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English (en)
Inventor
Matthieu Guitton
Jean-Luc Puel
Remy Pujol
Original Assignee
Auris Medical Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34966520&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CY1110495(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Auris Medical Ag filed Critical Auris Medical Ag
Publication of CY1110495T1 publication Critical patent/CY1110495T1/el

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/01—Hydrocarbons
    • A61K31/015—Hydrocarbons carbocyclic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/02—Halogenated hydrocarbons
    • A61K31/025—Halogenated hydrocarbons carbocyclic
    • A61K31/03—Halogenated hydrocarbons carbocyclic aromatic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4535—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom, e.g. pizotifen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/662—Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Η εφεύρεση αφορά μεθόδους για την πρόληψη ή/και θεραπεία εμβοής που προκαλείται από κοχλιακή διεγερτοτοξικότητα. Σε αυτές τις μεθόδους μια φαρμακευτική σύνθεση περιλαμβάνουσα έναν ανταγωνιστή υποδοχέα NMDA χορηγείται σε ένα άτομο που έχει ανάγκη μιας τέτοιας φαρμακευτικής αγωγής με κατάλληλες συσκευές ή/και φαρμακοτεχνικές μορφές για τοπική χορήγηση στο έσω ους. Η εμβοή που θα αποτρέπεται ή/και θα θεραπεύεται μπορεί να προκαλείται από ακουστικό τραύμα, πρεσβυακοΐα, ισχαιμία, ανοξία, θεραπεία με μια ή περισσότερες ωτοτοξικές φαρμακευτικές αγωγές, αιφνίδια κώφωση ή άλλο γεγονός που προκαλεί κοχλιακή διεγερτοτοξικότητα.
CY20091100944T 2004-03-29 2009-09-10 Χρηση ενος αγωνιστη υποδοχεα nmda για τη θεραπεια εμβοης που προκαλειται απο κοχλιακη διεγερτοτοξικοτητα CY1110495T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/812,298 US8268866B2 (en) 2004-03-29 2004-03-29 Methods for the treatment of tinnitus induced by cochlear excitotoxicity
EP05736619A EP1729753B1 (en) 2004-03-29 2005-03-29 Use of an nmda receptor antagonist for the treatment of tinnitus induced by cochlear excitotoxicity

Publications (1)

Publication Number Publication Date
CY1110495T1 true CY1110495T1 (el) 2015-04-29

Family

ID=34966520

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20091100944T CY1110495T1 (el) 2004-03-29 2009-09-10 Χρηση ενος αγωνιστη υποδοχεα nmda για τη θεραπεια εμβοης που προκαλειται απο κοχλιακη διεγερτοτοξικοτητα

Country Status (21)

Country Link
US (1) US8268866B2 (el)
EP (2) EP1729753B1 (el)
JP (2) JP4927706B2 (el)
KR (2) KR101429735B1 (el)
CN (2) CN104906079B (el)
AU (1) AU2005229543B2 (el)
BR (1) BRPI0508251A (el)
CA (1) CA2558896C (el)
CY (1) CY1110495T1 (el)
DE (1) DE602005015562D1 (el)
DK (1) DK1729753T3 (el)
ES (1) ES2330350T3 (el)
IL (1) IL177490A (el)
MX (1) MXPA06011078A (el)
NZ (1) NZ549399A (el)
PL (1) PL1729753T3 (el)
PT (1) PT1729753E (el)
RU (1) RU2380094C2 (el)
SI (1) SI1729753T1 (el)
WO (1) WO2005094799A2 (el)
ZA (1) ZA200607161B (el)

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Also Published As

Publication number Publication date
CN1972677B (zh) 2015-03-11
CN104906079B (zh) 2018-01-19
EP1729753B1 (en) 2009-07-22
DK1729753T3 (da) 2009-11-23
PT1729753E (pt) 2009-09-21
NZ549399A (en) 2009-12-24
PL1729753T3 (pl) 2010-01-29
KR20120049364A (ko) 2012-05-16
RU2006138153A (ru) 2008-05-10
ZA200607161B (en) 2007-11-28
CN1972677A (zh) 2007-05-30
WO2005094799A3 (en) 2006-03-02
WO2005094799A2 (en) 2005-10-13
JP2011105740A (ja) 2011-06-02
CN104906079A (zh) 2015-09-16
KR101429735B1 (ko) 2014-08-12
RU2380094C2 (ru) 2010-01-27
CA2558896A1 (en) 2005-10-13
EP1729753A2 (en) 2006-12-13
BRPI0508251A (pt) 2007-07-31
EP2077108A1 (en) 2009-07-08
AU2005229543B2 (en) 2009-12-03
KR20130103615A (ko) 2013-09-23
ES2330350T3 (es) 2009-12-09
IL177490A (en) 2013-10-31
IL177490A0 (en) 2006-12-10
CA2558896C (en) 2012-11-20
US8268866B2 (en) 2012-09-18
AU2005229543A1 (en) 2005-10-13
US20050214338A1 (en) 2005-09-29
MXPA06011078A (es) 2007-11-20
KR101451414B1 (ko) 2014-10-22
JP2007530622A (ja) 2007-11-01
JP4927706B2 (ja) 2012-05-09
SI1729753T1 (sl) 2009-12-31
DE602005015562D1 (de) 2009-09-03

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