CY1110037T1 - Σκευασματα για βενζιμιδαζολυλ πυριδυλ αιθερες - Google Patents

Σκευασματα για βενζιμιδαζολυλ πυριδυλ αιθερες

Info

Publication number
CY1110037T1
CY1110037T1 CY20101100427T CY101100427T CY1110037T1 CY 1110037 T1 CY1110037 T1 CY 1110037T1 CY 20101100427 T CY20101100427 T CY 20101100427T CY 101100427 T CY101100427 T CY 101100427T CY 1110037 T1 CY1110037 T1 CY 1110037T1
Authority
CY
Cyprus
Prior art keywords
packages
formulations
pyridyl ethers
benzimidazolyl pyridyl
compound
Prior art date
Application number
CY20101100427T
Other languages
English (en)
Inventor
Ahmad Hashash
Sean Ritchie
Kangwen Lin
Peng Shen
Augustus Okhamafe
Rampurna Gullapalli
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of CY1110037T1 publication Critical patent/CY1110037T1/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/143—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Dispersion Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Inorganic Chemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Παρέχονται σκευάσματα, που περιλαμβάνουν: μια ένωση του Χημικού τύπου (I), ένα φαρμακευτικώς αποδεκτό άλας αυτών, ή ένα μείγμα οποιωνδήποτε δυο ή περισσότερων εξ αυτών, και ένα συστατικό επιλεγμένο από έναν υδρόφιλο διαλύτη, έναν λιπόφιλο διαλύτη, έναν γαλακτωματοποιητή, ή ένα μείγμα οποιωνδήποτε δυο ή περισσότερων εξ αυτών, όπου η ένωση του Χημικού τύπου (I) είναι, σε μερικές εκδοχές, τα σκευάσματα είναι υγρά. Σε άλλες εκδοχές, τα σκευάσματα είναι στερεά. Επίσης παρέχονται μέθοδοι για την παρασκευή τέτοιων σκευασμάτων.
CY20101100427T 2006-07-21 2010-05-14 Σκευασματα για βενζιμιδαζολυλ πυριδυλ αιθερες CY1110037T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US83271506P 2006-07-21 2006-07-21
EP07810647A EP2046292B1 (en) 2006-07-21 2007-07-20 Formulations for benzimidazolyl pyridyl ethers

Publications (1)

Publication Number Publication Date
CY1110037T1 true CY1110037T1 (el) 2015-01-14

Family

ID=38819293

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20101100427T CY1110037T1 (el) 2006-07-21 2010-05-14 Σκευασματα για βενζιμιδαζολυλ πυριδυλ αιθερες

Country Status (20)

Country Link
US (1) US8455662B2 (el)
EP (1) EP2046292B1 (el)
JP (1) JP2009544617A (el)
KR (1) KR20090033904A (el)
CN (1) CN101516335B (el)
AT (1) ATE459338T1 (el)
AU (1) AU2007275634B2 (el)
BR (1) BRPI0715423A2 (el)
CA (1) CA2657346A1 (el)
CY (1) CY1110037T1 (el)
DE (1) DE602007005139D1 (el)
DK (1) DK2046292T3 (el)
ES (1) ES2340631T3 (el)
HR (1) HRP20100293T1 (el)
MX (1) MX2009000770A (el)
PL (1) PL2046292T3 (el)
PT (1) PT2046292E (el)
RU (2) RU2452469C2 (el)
SI (1) SI2046292T1 (el)
WO (1) WO2008011154A2 (el)

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PE20070335A1 (es) * 2005-08-30 2007-04-21 Novartis Ag Benzimidazoles sustituidos y metodos para su preparacion
PE20130814A1 (es) * 2006-08-30 2013-08-08 Novartis Ag Sales de benzimidazolil piridil eteres y formulaciones que las contienen
RU2483064C2 (ru) * 2007-03-02 2013-05-27 Новартис Аг Твердые формы ингибитора raf-киназы
WO2010040055A2 (en) * 2008-10-03 2010-04-08 Intekrin Therapeutics, Inc. Oral pharmaceutical formulations for antidiabetic compounds
JO3434B1 (ar) * 2009-07-31 2019-10-20 Millennium Pharm Inc مركبات صيدلانية لمعالجة السرطان وامراض واضطرابات اخري
EP2588081A4 (en) * 2010-06-29 2014-12-10 Verastem Inc ORAL FORMULATION OF CHINESE INHIBITORS
JP5923499B2 (ja) 2010-06-30 2016-05-24 ベラステム インコーポレイテッド キナーゼインヒビターの合成および使用
CN102336740B (zh) * 2010-07-27 2013-07-24 中国科学院上海药物研究所 一类咪唑类化合物及其用途
CN103301067B (zh) * 2012-03-15 2018-09-11 苏州泽璟生物制药有限公司 一种改善吸收性能的固体分散体及其制备
US9724354B2 (en) 2013-03-22 2017-08-08 Millennium Pharmaceuticals, Inc. Combination of catalytic mTORC1/2 inhibitors and selective inhibitors of Aurora A kinase
US10561627B2 (en) * 2014-12-31 2020-02-18 Eric Morrison Ibuprofen nanoparticle carriers encapsulated with hermetic surfactant films
SG10202103552XA (en) 2015-03-09 2021-05-28 Intekrin Therapeutics Inc Methods for the treatment of nonalcoholic fatty liver disease and/or lipodystrophy
EP3606527A1 (en) 2017-04-03 2020-02-12 Coherus Biosciences, Inc. Ppar-gamma agonist for treatment of progressive supranuclear palsy

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Also Published As

Publication number Publication date
EP2046292A2 (en) 2009-04-15
AU2007275634A1 (en) 2008-01-24
WO2008011154A2 (en) 2008-01-24
RU2009105819A (ru) 2010-08-27
PL2046292T3 (pl) 2010-08-31
DE602007005139D1 (de) 2010-04-15
BRPI0715423A2 (pt) 2013-07-02
US20100040677A1 (en) 2010-02-18
PT2046292E (pt) 2010-04-26
RU2012107218A (ru) 2013-09-10
US8455662B2 (en) 2013-06-04
JP2009544617A (ja) 2009-12-17
CN101516335B (zh) 2014-01-08
AU2007275634B2 (en) 2011-01-20
DK2046292T3 (da) 2010-06-07
SI2046292T1 (sl) 2010-06-30
MX2009000770A (es) 2009-01-28
EP2046292B1 (en) 2010-03-03
WO2008011154A3 (en) 2008-06-26
CA2657346A1 (en) 2008-01-24
HRP20100293T1 (hr) 2010-06-30
ES2340631T3 (es) 2010-06-07
CN101516335A (zh) 2009-08-26
ATE459338T1 (de) 2010-03-15
RU2452469C2 (ru) 2012-06-10
KR20090033904A (ko) 2009-04-06

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