CY1108875T1 - Βλεννοπροσφυτικα σκευασματα που περιεχουν ξυλογλυκανη και ειναι χρησιμα σε ιατρικες συσκευες και σε φαρμακευτικα σκευασματα - Google Patents
Βλεννοπροσφυτικα σκευασματα που περιεχουν ξυλογλυκανη και ειναι χρησιμα σε ιατρικες συσκευες και σε φαρμακευτικα σκευασματαInfo
- Publication number
- CY1108875T1 CY1108875T1 CY20091100281T CY091100281T CY1108875T1 CY 1108875 T1 CY1108875 T1 CY 1108875T1 CY 20091100281 T CY20091100281 T CY 20091100281T CY 091100281 T CY091100281 T CY 091100281T CY 1108875 T1 CY1108875 T1 CY 1108875T1
- Authority
- CY
- Cyprus
- Prior art keywords
- medical devices
- xyloglycan
- mucilage
- useful
- pharmaceutical formulations
- Prior art date
Links
- 229920000715 Mucilage Polymers 0.000 title 1
- 239000000853 adhesive Substances 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 abstract 3
- 210000004400 mucous membrane Anatomy 0.000 abstract 3
- 238000009472 formulation Methods 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 230000003232 mucoadhesive effect Effects 0.000 abstract 2
- 229920002000 Xyloglucan Polymers 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 239000007864 aqueous solution Substances 0.000 abstract 1
- 239000003405 delayed action preparation Substances 0.000 abstract 1
- 239000003974 emollient agent Substances 0.000 abstract 1
- 239000003906 humectant Substances 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 229920000642 polymer Polymers 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
- A61K31/416—1,2-Diazoles condensed with carbocyclic ring systems, e.g. indazole
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/716—Glucans
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/23—Calcitonins
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- A—HUMAN NECESSITIES
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- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
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- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
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- A61K9/10—Dispersions; Emulsions
- A61K9/12—Aerosols; Foams
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
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- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
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- Otolaryngology (AREA)
- Urology & Nephrology (AREA)
- Reproductive Health (AREA)
- Gynecology & Obstetrics (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Endocrinology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
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- Inorganic Chemistry (AREA)
- Molecular Biology (AREA)
- Pain & Pain Management (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Virology (AREA)
- Rheumatology (AREA)
- Tropical Medicine & Parasitology (AREA)
Abstract
Αντικείμενο της εφεύρεσης αποτελούν βλεννοπροσφυτικά και ελεγχόμενης έκλυσης σκευάσματα που αποτελούνται από υδατικά διαλύματα που περιέχουν 0,05% έως 5% κατά βάρος ενός φυσικού καθαρισμένου πολυμερούς που έχει δομή ξυλογλυκάνης και 10% έως 70% κατά βάρος γλυκερόλη. Αυτά τα σκευάσματα είναι κατάλληλα για εφαρμογή σε ανθρώπινες βλεννώδεις μεμβράνες, όπως οι ρινικές, στοματικές και κολπικές βλεννώδεις μεμβράνες, ως υγραντικά και μαλακτικά αντιδραστήρια ή ως φαρμακευτικό σύστημα έκλυσης. Περαιτέρω αντικείμενα της εφεύρεσης αποτελούν φαρμακευτικά σκευάσματα και ιατρικές συσκευές κατάλληλες για εφαρμογή σε ανθρώπινες βλεννώδεις μεμβράνες, που περιέχουν τα βλεννοπροσφυτικά και ελεγχόμενης έκλυσης σκευάσματα μαζί με δραστικά συστατικά και έκδοχα.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT000388A ITBO20050388A1 (it) | 2005-06-06 | 2005-06-06 | Formulazione mucoadesive utili in dispositivi medici in preparazioni farmaceutiche |
EP06754047A EP1898876B1 (en) | 2005-06-06 | 2006-06-01 | Mucoadhesive xyloglucan-containing formulations useful in medical devices and in pharmaceutical presentations |
Publications (1)
Publication Number | Publication Date |
---|---|
CY1108875T1 true CY1108875T1 (el) | 2014-07-02 |
Family
ID=36954507
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY20091100281T CY1108875T1 (el) | 2005-06-06 | 2009-03-12 | Βλεννοπροσφυτικα σκευασματα που περιεχουν ξυλογλυκανη και ειναι χρησιμα σε ιατρικες συσκευες και σε φαρμακευτικα σκευασματα |
Country Status (22)
Country | Link |
---|---|
US (3) | US20090081133A1 (el) |
EP (1) | EP1898876B1 (el) |
JP (1) | JP5118633B2 (el) |
KR (1) | KR101337578B1 (el) |
CN (2) | CN101180036B (el) |
AT (1) | ATE418324T1 (el) |
BR (1) | BRPI0611400B8 (el) |
CA (1) | CA2604768C (el) |
CY (1) | CY1108875T1 (el) |
DE (1) | DE602006004451D1 (el) |
DK (1) | DK1898876T3 (el) |
ES (1) | ES2318756T3 (el) |
IL (1) | IL186655A (el) |
IT (1) | ITBO20050388A1 (el) |
MX (1) | MX2007015074A (el) |
NO (1) | NO338991B1 (el) |
PL (1) | PL1898876T3 (el) |
PT (1) | PT1898876E (el) |
RU (1) | RU2403012C2 (el) |
SI (1) | SI1898876T1 (el) |
UA (1) | UA90507C2 (el) |
WO (1) | WO2006131262A1 (el) |
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CN103189046B (zh) | 2010-09-09 | 2016-09-07 | 玫琳凯有限公司 | 包含植物提取物的局部护肤制剂 |
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US9301920B2 (en) | 2012-06-18 | 2016-04-05 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
US9091622B2 (en) | 2011-12-20 | 2015-07-28 | Exxonmobil Upstream Research Company | Capillary-based calibration standards for measurement of permeability |
US10806740B2 (en) | 2012-06-18 | 2020-10-20 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
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US11266661B2 (en) | 2012-12-21 | 2022-03-08 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
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CA2945631C (en) * | 2014-04-15 | 2023-04-11 | Novintethical Pharma Sa | Compositions based on xyloglucan and proteins for the treatment of intestinal disorders |
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EP3174542A4 (en) | 2014-07-29 | 2018-01-03 | TherapeuticsMD, Inc. | Transdermal cream |
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2005
- 2005-06-06 IT IT000388A patent/ITBO20050388A1/it unknown
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2006
- 2006-01-06 UA UAA200711344A patent/UA90507C2/uk unknown
- 2006-06-01 EP EP06754047A patent/EP1898876B1/en active Active
- 2006-06-01 CN CN2006800176445A patent/CN101180036B/zh active Active
- 2006-06-01 PT PT06754047T patent/PT1898876E/pt unknown
- 2006-06-01 CN CN2010105570198A patent/CN102079794B/zh active Active
- 2006-06-01 ES ES06754047T patent/ES2318756T3/es active Active
- 2006-06-01 KR KR1020077028142A patent/KR101337578B1/ko active IP Right Grant
- 2006-06-01 BR BRPI0611400A patent/BRPI0611400B8/pt not_active IP Right Cessation
- 2006-06-01 AT AT06754047T patent/ATE418324T1/de active
- 2006-06-01 RU RU2007143998/15A patent/RU2403012C2/ru active
- 2006-06-01 CA CA2604768A patent/CA2604768C/en active Active
- 2006-06-01 MX MX2007015074A patent/MX2007015074A/es active IP Right Grant
- 2006-06-01 DE DE602006004451T patent/DE602006004451D1/de active Active
- 2006-06-01 SI SI200630188T patent/SI1898876T1/sl unknown
- 2006-06-01 US US11/921,286 patent/US20090081133A1/en not_active Abandoned
- 2006-06-01 DK DK06754047T patent/DK1898876T3/da active
- 2006-06-01 PL PL06754047T patent/PL1898876T3/pl unknown
- 2006-06-01 JP JP2008514019A patent/JP5118633B2/ja active Active
- 2006-06-01 WO PCT/EP2006/005240 patent/WO2006131262A1/en active Application Filing
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2007
- 2007-10-15 IL IL186655A patent/IL186655A/en active IP Right Grant
- 2007-11-26 NO NO20076083A patent/NO338991B1/no not_active IP Right Cessation
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2009
- 2009-03-12 CY CY20091100281T patent/CY1108875T1/el unknown
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2011
- 2011-10-19 US US13/277,130 patent/US20120088726A1/en not_active Abandoned
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2013
- 2013-01-23 US US13/747,889 patent/US20130183325A1/en not_active Abandoned
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