IT201700108526A1 - Composizioni orali per il trattamento del refluso gastroesofageo. - Google Patents

Composizioni orali per il trattamento del refluso gastroesofageo.

Info

Publication number
IT201700108526A1
IT201700108526A1 IT102017000108526A IT201700108526A IT201700108526A1 IT 201700108526 A1 IT201700108526 A1 IT 201700108526A1 IT 102017000108526 A IT102017000108526 A IT 102017000108526A IT 201700108526 A IT201700108526 A IT 201700108526A IT 201700108526 A1 IT201700108526 A1 IT 201700108526A1
Authority
IT
Italy
Prior art keywords
gastroesophageal
reflection
treatment
oral compositions
oral
Prior art date
Application number
IT102017000108526A
Other languages
English (en)
Inventor
Paola Maffei
Marco Mascagni
Giuseppe Claudio Viscomi
Original Assignee
Alfasigma Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alfasigma Spa filed Critical Alfasigma Spa
Priority to IT102017000108526A priority Critical patent/IT201700108526A1/it
Priority to PCT/EP2018/075200 priority patent/WO2019063363A1/en
Priority to CN201880059051.8A priority patent/CN111093628B/zh
Priority to US16/349,711 priority patent/US11241452B2/en
Priority to MX2020003786A priority patent/MX2020003786A/es
Priority to CN202311516607.0A priority patent/CN117503794A/zh
Priority to EP18770024.0A priority patent/EP3687494A1/en
Priority to EA202090827A priority patent/EA202090827A1/ru
Publication of IT201700108526A1 publication Critical patent/IT201700108526A1/it

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/737Sulfated polysaccharides, e.g. chondroitin sulfate, dermatan sulfate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726Glycosaminoglycans, i.e. mucopolysaccharides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716Glucans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12Carboxylic acids; Salts or anhydrides thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/20Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38Cellulose; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0087Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Molecular Biology (AREA)
  • Inorganic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Dermatology (AREA)
  • Biochemistry (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
IT102017000108526A 2017-09-28 2017-09-28 Composizioni orali per il trattamento del refluso gastroesofageo. IT201700108526A1 (it)

Priority Applications (8)

Application Number Priority Date Filing Date Title
IT102017000108526A IT201700108526A1 (it) 2017-09-28 2017-09-28 Composizioni orali per il trattamento del refluso gastroesofageo.
PCT/EP2018/075200 WO2019063363A1 (en) 2017-09-28 2018-09-18 ORAL COMPOSITIONS FOR THE TREATMENT OF GASTRO-ESOPHAGEAL REFLUX
CN201880059051.8A CN111093628B (zh) 2017-09-28 2018-09-18 治疗胃食管反流的口服组合物
US16/349,711 US11241452B2 (en) 2017-09-28 2018-09-18 Oral compositions for the treatment of gastroesophageal reflux
MX2020003786A MX2020003786A (es) 2017-09-28 2018-09-18 Composiciones orales para el tratamiento de reflujo gastroesofagico.
CN202311516607.0A CN117503794A (zh) 2017-09-28 2018-09-18 治疗胃食管反流的口服组合物
EP18770024.0A EP3687494A1 (en) 2017-09-28 2018-09-18 Oral compositions for the treatment of gastroesophageal reflux
EA202090827A EA202090827A1 (ru) 2017-09-28 2018-09-18 Пероральные композиции для лечения гастроэзофагеального рефлюкса

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT102017000108526A IT201700108526A1 (it) 2017-09-28 2017-09-28 Composizioni orali per il trattamento del refluso gastroesofageo.

Publications (1)

Publication Number Publication Date
IT201700108526A1 true IT201700108526A1 (it) 2019-03-28

Family

ID=61024911

Family Applications (1)

Application Number Title Priority Date Filing Date
IT102017000108526A IT201700108526A1 (it) 2017-09-28 2017-09-28 Composizioni orali per il trattamento del refluso gastroesofageo.

Country Status (7)

Country Link
US (1) US11241452B2 (it)
EP (1) EP3687494A1 (it)
CN (2) CN117503794A (it)
EA (1) EA202090827A1 (it)
IT (1) IT201700108526A1 (it)
MX (1) MX2020003786A (it)
WO (1) WO2019063363A1 (it)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT202000022471A1 (it) * 2020-09-23 2022-03-23 Sofar Swiss Sa Composizioni comprendenti una condroitina vegetale o un suo analogo e loro uso nel trattamento disturbi della mucosa del tratto orale, faringo-laringeo e/o gastro-esofageo
TWI777673B (zh) * 2021-07-16 2022-09-11 陳昭誠 由β-1-4-葡聚醣形成之纖維於製備用於治療或預防胃食道逆流之組成物之用途

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060292184A1 (en) * 2003-02-20 2006-12-28 Richardson Johnathan C Bioadhesive liquid composition which is substantially free of water
US20120238630A1 (en) * 2009-12-01 2012-09-20 Alfa Wassermann S.P.A. Compositions comprising nonsteroidal anti - inflammatory drugs
US20130183325A1 (en) * 2005-06-06 2013-07-18 Alfa Wassermann S.P.A. Mucoadhesive xyloglucan-containing formulations useful in medical devices and in pharmaceutical formulations
US20140107064A1 (en) * 2008-05-13 2014-04-17 Apharm S.R.L. Glycosaminoglycan oral use and compositions

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU7201998A (en) * 1997-05-06 1998-11-27 Zhi Liu Drug delivery system
GB9910212D0 (en) 1999-05-05 1999-06-30 Reckitt & Colmann Prod Ltd Improvements in or relating to organic compositions
US7504387B2 (en) 2002-10-16 2009-03-17 Arthrodynamic Technologies, Animal Health Division, Inc. Glycosaminoglycan composition and method for treatment and prevention of interstitial cystitis
BRPI0815975B8 (pt) * 2007-08-27 2021-05-25 Biogenerix Ag preparação aquosa, recipiente farmacêutico, processo para preparar uma preparação aquosa, e, uso de uma preparação aquosa
EA018333B1 (ru) 2008-05-13 2013-07-30 Афарм С.Р.Л. Применение гликозаминогликанов для перорального введения и композиции гликозаминогликанов
EP2208500A1 (en) * 2009-01-16 2010-07-21 Bionap S.r.L. Compositions for the treatment of gerd (gastroesophageal reflux disease)
ES2428337T3 (es) 2009-05-25 2013-11-07 Sofar Swiss Sa Uso de una combinación fija de glucosaminoglucanos y composición masticable que comprende dicha combinación fija
CA2822227C (en) * 2010-12-23 2017-01-17 Colgate-Palmolive Company Fluid compositions comprising a structuring agent

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060292184A1 (en) * 2003-02-20 2006-12-28 Richardson Johnathan C Bioadhesive liquid composition which is substantially free of water
US20130183325A1 (en) * 2005-06-06 2013-07-18 Alfa Wassermann S.P.A. Mucoadhesive xyloglucan-containing formulations useful in medical devices and in pharmaceutical formulations
US20140107064A1 (en) * 2008-05-13 2014-04-17 Apharm S.R.L. Glycosaminoglycan oral use and compositions
US20120238630A1 (en) * 2009-12-01 2012-09-20 Alfa Wassermann S.P.A. Compositions comprising nonsteroidal anti - inflammatory drugs

Also Published As

Publication number Publication date
CN117503794A (zh) 2024-02-06
MX2020003786A (es) 2020-08-03
WO2019063363A1 (en) 2019-04-04
US11241452B2 (en) 2022-02-08
EP3687494A1 (en) 2020-08-05
CN111093628B (zh) 2023-11-17
US20190314402A1 (en) 2019-10-17
CN111093628A (zh) 2020-05-01
EA202090827A1 (ru) 2020-06-24

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