CY1106727T1 - Ινδανυλ παραγωγα για την αντιμετωπιση ασθενειων αεραγωγων - Google Patents

Ινδανυλ παραγωγα για την αντιμετωπιση ασθενειων αεραγωγων

Info

Publication number
CY1106727T1
CY1106727T1 CY20071100933T CY071100933T CY1106727T1 CY 1106727 T1 CY1106727 T1 CY 1106727T1 CY 20071100933 T CY20071100933 T CY 20071100933T CY 071100933 T CY071100933 T CY 071100933T CY 1106727 T1 CY1106727 T1 CY 1106727T1
Authority
CY
Cyprus
Prior art keywords
treatment
tract disease
indanyl derivatives
indanyl
derivatives
Prior art date
Application number
CY20071100933T
Other languages
English (en)
Inventor
Bernard Cuenoud
Robin Alec Fairhurst
Nicholas Lowther
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of CY1106727T1 publication Critical patent/CY1106727T1/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4704—2-Quinolinones, e.g. carbostyril
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/16—Central respiratory analeptics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Quinoline Compounds (AREA)
  • Steroid Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Μια φαρμακευτική ουσία που περιλαμβάνει, ξεχωριστά ή μαζί (Α) μια ένωση του χημικού τύπου (Ι) σε ελεύθερη μορφή ή σε μορφή φαρμακευτικώς αποδεκτού άλατος ή σε μορφή διαλύματος και (Β) ένα κορτικοστεροειδές, για ταυτόχρονη, διαδοχική ή ξεχωριστή χορήγηση στην αντιμετώπιση μιας φλεγμονώδους ή αποφρακτικής νόσου των αεραγωγών, με την μοριακή αναλογία του (Α) και του (Β) να κυμαίνεται από 100:1 έως 1:300.
CY20071100933T 2000-12-04 2007-07-13 Ινδανυλ παραγωγα για την αντιμετωπιση ασθενειων αεραγωγων CY1106727T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0029562.6A GB0029562D0 (en) 2000-12-04 2000-12-04 Organic compounds
PCT/EP2001/014122 WO2002045703A2 (en) 2000-12-04 2001-12-03 Mixtures or organic compounds for the treatmentof airway diseases

Publications (1)

Publication Number Publication Date
CY1106727T1 true CY1106727T1 (el) 2012-05-23

Family

ID=9904414

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20071100933T CY1106727T1 (el) 2000-12-04 2007-07-13 Ινδανυλ παραγωγα για την αντιμετωπιση ασθενειων αεραγωγων

Country Status (28)

Country Link
US (5) US6800643B2 (el)
EP (2) EP1341542B1 (el)
JP (2) JP2004514739A (el)
KR (1) KR100523541B1 (el)
CN (1) CN1212119C (el)
AT (1) ATE361077T1 (el)
AU (2) AU2002217082B2 (el)
BR (1) BRPI0115910B8 (el)
CA (1) CA2427282C (el)
CY (1) CY1106727T1 (el)
CZ (1) CZ304294B6 (el)
DE (1) DE60128258T2 (el)
DK (1) DK1341542T3 (el)
EC (1) ECSP034620A (el)
ES (1) ES2284732T3 (el)
GB (1) GB0029562D0 (el)
HK (1) HK1059564A1 (el)
HU (1) HU229552B1 (el)
IL (2) IL155709A0 (el)
MX (1) MXPA03004976A (el)
NO (1) NO325692B1 (el)
NZ (1) NZ525731A (el)
PL (1) PL204002B1 (el)
PT (1) PT1341542E (el)
RU (1) RU2292890C2 (el)
SK (1) SK287331B6 (el)
WO (1) WO2002045703A2 (el)
ZA (1) ZA200303399B (el)

Families Citing this family (60)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9006175B2 (en) 1999-06-29 2015-04-14 Mannkind Corporation Potentiation of glucose elimination
AR028948A1 (es) 2000-06-20 2003-05-28 Astrazeneca Ab Compuestos novedosos
GB0029562D0 (en) * 2000-12-04 2001-01-17 Novartis Ag Organic compounds
JP4681231B2 (ja) 2002-03-20 2011-05-11 マンカインド コーポレイション 吸入装置
US20040146509A1 (en) * 2002-07-25 2004-07-29 Zhihe Li Methods for improvement of lung function using TGF-beta inhibitors
PA8578101A1 (es) 2002-08-13 2004-05-07 Warner Lambert Co Derivados de heterobiarilo como inhibidores de metaloproteinasa de la matriz
US7250426B2 (en) * 2002-11-29 2007-07-31 Boehringer Ingelheim Pharma Gmbh & Co Kg Tiotropium-containing pharmaceutical combination for inhalation
TWI324151B (en) * 2003-04-02 2010-05-01 Novartis Ag Process for the preparation of 5-(haloacetyl)-8-substituted oxy-(1h)-quinolin-2-ones
PT1613315E (pt) * 2003-04-04 2009-04-22 Novartis Ag Derivados da quinolina-2-ona para o tratamento de doenças das vias aéreas respiratórias
GB0307856D0 (en) * 2003-04-04 2003-05-14 Novartis Ag Organic compounds
GB0411056D0 (en) 2004-05-18 2004-06-23 Novartis Ag Organic compounds
WO2006023849A2 (en) 2004-08-20 2006-03-02 Mannkind Corporation Catalysis of diketopiperazine synthesis
DK2322180T3 (en) 2004-08-23 2015-06-15 Mannkind Corp Diketopiperazinsalte for drug delivery
KR100666220B1 (ko) * 2005-01-31 2007-01-09 영남대학교 산학협력단 구내염 치료용 분사제 조성물
MX2007012084A (es) * 2005-03-30 2007-11-21 Schering Corp Medicamentos y metodos que combinan un anticolinergico, un corticosteroide y un agonista beta de accion prolongada.
GB0511066D0 (en) * 2005-05-31 2005-07-06 Novartis Ag Organic compounds
GB0511065D0 (en) * 2005-05-31 2005-07-06 Novartis Ag Organic compounds
TW200738634A (en) 2005-08-02 2007-10-16 Astrazeneca Ab New salt
TW200744612A (en) * 2005-08-26 2007-12-16 Astrazeneca Ab New combination
ES2559677T3 (es) 2005-09-14 2016-02-15 Mannkind Corporation Método de formulación de fármacos basado en aumentar la afinidad de los principios activos por superficies de partículas microcristalinas
GB0523655D0 (en) * 2005-11-21 2005-12-28 Novartis Ag Organic compounds
GB0523656D0 (en) * 2005-11-21 2005-12-28 Novartis Ag Organic compounds
JP2009520822A (ja) * 2005-12-20 2009-05-28 ティカ レーケメデル アーベー コルチコステロイドを送達するための方法およびシステム
MX2008010721A (es) 2006-02-22 2008-09-01 Mannkind Corp Un metodo para mejorar las propiedades farmaceuticas de microparticulas que contienen dicetopiperazina y un agente activo.
US20070225233A1 (en) * 2006-03-27 2007-09-27 Tsu-Fuh Yeh Reducing the risk of chronic lung disease in infants
CN101479245B (zh) * 2006-06-30 2013-05-22 诺瓦提斯公司 喹啉酮衍生物和其药物组合物
EP1878722A1 (en) * 2006-07-13 2008-01-16 Novartis AG Quinolinone derivatives and their pharmaceutical compositions
DK2230934T3 (da) 2007-12-14 2012-11-26 Aerodesigns Inc Afgivelse af aerosoliserbare næringsmiddelprodukter
MY176697A (en) 2008-06-13 2020-08-19 Mannkind Corp A dry powder inhaler and system for drug delivery
US8485180B2 (en) 2008-06-13 2013-07-16 Mannkind Corporation Dry powder drug delivery system
DK2609954T3 (da) 2008-06-20 2022-02-14 Mannkind Corp Interaktivt apparat til realtidsafbildning af inhalationspræstationer
TWI614024B (zh) 2008-08-11 2018-02-11 曼凱公司 超快起作用胰島素之用途
US8314106B2 (en) 2008-12-29 2012-11-20 Mannkind Corporation Substituted diketopiperazine analogs for use as drug delivery agents
DK2405963T3 (da) 2009-03-11 2013-12-16 Mannkind Corp Apparat, system og fremgangsmåde til at måle modstand i en inhalator
KR101748892B1 (ko) 2009-05-29 2017-06-19 펄 테라퓨틱스 인코포레이티드 지속형 무스카린 안타고니스트 및 지속형 ｂ₂아드레날린 수용체 아고니스트의 폐 전달용 조성물, 및 연관된 방법 및 시스템
CA2764505C (en) 2009-06-12 2018-09-25 Mannkind Corporation Diketopiperazine microparticles with defined specific surface areas
KR100940388B1 (ko) * 2009-07-01 2010-02-02 유병덕 스크류탈수기 및 이를 포함하는 유기성폐기물 건조장치
CA2778698A1 (en) 2009-11-03 2011-05-12 Mannkind Corporation An apparatus and method for simulating inhalation efforts
CN102985125A (zh) 2010-06-21 2013-03-20 曼金德公司 干粉药物输送***和方法
AU2011278096B2 (en) * 2010-07-16 2014-08-28 Cipla Limited Pharmaceutical compositions comprising R (+) budesonide and one or more bronchodilators
CN107998109A (zh) 2010-10-12 2018-05-08 西普拉有限公司 药物组合物
WO2012135765A2 (en) 2011-04-01 2012-10-04 Mannkind Corporation Blister package for pharmaceutical cartridges
WO2012174472A1 (en) 2011-06-17 2012-12-20 Mannkind Corporation High capacity diketopiperazine microparticles
CN102247380A (zh) * 2011-08-19 2011-11-23 北京阜康仁生物制药科技有限公司 一种以布***与茚达特罗为活性成分的复方制剂
WO2013063160A1 (en) 2011-10-24 2013-05-02 Mannkind Corporation Methods and compositions for treating pain
WO2013132514A2 (en) * 2012-03-09 2013-09-12 Rao Davuluri Ramamohan A novel process for the preparation of (r)-5-[2-[(5, 6-diethyl-2, 3-dihydro-1h-inden-2-yl) amino]-1-hydroxyethyl]-8-hydroxy quinolin-2(1h)-one
WO2014008639A1 (zh) * 2012-07-11 2014-01-16 上海威智医药科技有限公司 制备茚达特罗的方法
MY176411A (en) 2012-07-12 2020-08-06 Mannkind Corp Dry powder drug delivery system and methods
WO2014044288A1 (en) 2012-09-21 2014-03-27 Crystal Pharma Sa Methods for the preparation of indacaterol and pharmaceutically acceptable salts thereof
US10159644B2 (en) 2012-10-26 2018-12-25 Mannkind Corporation Inhalable vaccine compositions and methods
US10421729B2 (en) 2013-03-15 2019-09-24 Mannkind Corporation Microcrystalline diketopiperazine compositions and methods
BR112016000937A8 (pt) 2013-07-18 2021-06-22 Mannkind Corp formulações farmacêuticas de pó seco, método para a fabricação de uma formulação de pó seco e uso de uma formulação farmacêutica de pó seco
US11446127B2 (en) 2013-08-05 2022-09-20 Mannkind Corporation Insufflation apparatus and methods
US10307464B2 (en) 2014-03-28 2019-06-04 Mannkind Corporation Use of ultrarapid acting insulin
US10561806B2 (en) 2014-10-02 2020-02-18 Mannkind Corporation Mouthpiece cover for an inhaler
ITUB20153978A1 (it) * 2015-09-28 2017-03-28 Laboratorio Chimico Int S P A Procedimento per la preparazione di derivati di indanammina e di nuovi intermedi di sintesi.
CN107868045A (zh) * 2016-09-28 2018-04-03 四川海思科制药有限公司 一种茚达特罗中间体的制备方法
CN106831445B (zh) * 2016-11-22 2019-01-22 斯芬克司药物研发（天津）股份有限公司 一种茚基胺化合物的制备方法
CN110229078A (zh) * 2019-05-22 2019-09-13 博诺康源(北京)药业科技有限公司 一种茚达特罗起始原料开环杂质的制备
CN114751857A (zh) * 2022-04-29 2022-07-15 梯尔希（南京）药物研发有限公司 一种茚达特罗杂质的制备方法

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4607028A (en) * 1983-08-18 1986-08-19 Ciba-Geigy Corporation Novel carboxylic acid esters
WO1993018007A1 (en) * 1992-03-13 1993-09-16 Tokyo Tanabe Company Limited Novel carbostyril derivative
GB9405019D0 (en) * 1994-03-15 1994-04-27 Smithkline Beecham Plc Novel compounds
GB9501286D0 (en) * 1995-01-24 1995-03-15 Ciba Geigy Ag Pharmaceutical compositions and preparations thereof
DE69630639T2 (de) * 1995-08-16 2004-09-16 Huntington Medical Research Institutes, Pasadena Rhodamin 123 Zusammensetzungen für Behandlung von Prostatakrebs
GB9603237D0 (en) 1996-02-16 1996-04-17 Sandoz Ltd Organic compounds
TW375604B (en) 1996-02-19 1999-12-01 Kissei Pharmaceutical 3,4-di-substituting phenyl-ethanolamine-tetrahydronaphthyl carboxylic amide derivatives
GB9610122D0 (en) * 1996-05-15 1996-07-24 Reckitt & Colmann Prod Ltd Organic compositions
ES2149742T1 (es) * 1997-07-03 2000-11-16 Asahi Chemical Ind Nuevos compuestos triciclicos que tienen anillos saturados y composiciones medicinales que contienen los mismos.
GB9902689D0 (en) * 1999-02-08 1999-03-31 Novartis Ag Organic compounds
GB9913083D0 (en) * 1999-06-04 1999-08-04 Novartis Ag Organic compounds
US6448239B1 (en) 1999-06-03 2002-09-10 Trustees Of Princeton University Peroxynitrite decomposition catalysts and methods of use thereof
US6664235B1 (en) * 1999-08-20 2003-12-16 Riken Medicaments comprising sialic acid derivatives as active ingredients
EP1311294A2 (en) * 2000-08-04 2003-05-21 Longwood Pharmaceutical Research, Inc. Formulations of mometasone and a bronchodilator for pulmonary administration
GB0029562D0 (en) * 2000-12-04 2001-01-17 Novartis Ag Organic compounds

Also Published As

Publication number Publication date
JP2004514739A (ja) 2004-05-20
HUP0302571A2 (hu) 2003-11-28
ATE361077T1 (de) 2007-05-15
CZ20031537A3 (cs) 2003-10-15
JP2007302684A (ja) 2007-11-22
EP1341542A2 (en) 2003-09-10
DE60128258T2 (de) 2007-12-27
RU2292890C2 (ru) 2007-02-10
AU2002217082B2 (en) 2005-04-07
EP1772142A3 (en) 2011-09-14
BRPI0115910B1 (pt) 2019-12-31
NO325692B1 (no) 2008-07-07
US7622484B2 (en) 2009-11-24
US7008951B2 (en) 2006-03-07
ES2284732T3 (es) 2007-11-16
RU2003119549A (ru) 2005-02-10
ECSP034620A (es) 2003-06-25
NO20032510L (no) 2003-06-03
DK1341542T3 (da) 2007-09-03
US20040038951A1 (en) 2004-02-26
IL155709A0 (en) 2003-11-23
KR100523541B1 (ko) 2005-10-25
US20060052352A1 (en) 2006-03-09
CZ304294B6 (cs) 2014-02-19
WO2002045703A2 (en) 2002-06-13
BRPI0115910B8 (pt) 2021-05-25
NZ525731A (en) 2004-11-26
NO20032510D0 (no) 2003-06-03
IL155709A (en) 2008-11-26
CN1212119C (zh) 2005-07-27
US6800643B2 (en) 2004-10-05
AU1708202A (en) 2002-06-18
CN1477963A (zh) 2004-02-25
EP1341542B1 (en) 2007-05-02
ZA200303399B (en) 2004-04-23
SK6502003A3 (en) 2003-12-02
US20120108555A1 (en) 2012-05-03
DE60128258D1 (de) 2007-06-14
GB0029562D0 (en) 2001-01-17
PT1341542E (pt) 2007-08-01
MXPA03004976A (es) 2003-09-05
BR0115910A (pt) 2004-01-20
WO2002045703A3 (en) 2003-03-13
US20050009795A1 (en) 2005-01-13
PL204002B1 (pl) 2009-12-31
EP1772142A2 (en) 2007-04-11
PL362443A1 (en) 2004-11-02
CA2427282A1 (en) 2002-06-13
SK287331B6 (sk) 2010-07-07
KR20030048065A (ko) 2003-06-18
HUP0302571A3 (en) 2005-05-30
HK1059564A1 (en) 2004-07-09
CA2427282C (en) 2010-10-19
HU229552B1 (en) 2014-01-28
US20100068288A1 (en) 2010-03-18

Similar Documents

Publication Publication Date Title
CY1106727T1 (el) Ινδανυλ παραγωγα για την αντιμετωπιση ασθενειων αεραγωγων
CY1105707T1 (el) Συνδυασμοι φορμοτερολης και ενος αλατος τριοτροπιου
CY1117470T1 (el) Στερεα δοσολογικα σκευασματα με βελτιωμενη ενδοστοματικη προσροφηση
CY1111088T1 (el) Θεραπευτικη φαρμακοτεχνικη μορφη για χορηγηση τολτεροδινης με ελεγχομενη απελευθερωση
CY1105120T1 (el) Η αντιμετωπιση αναπνευστικων νοσων
DE60325354D1 (de) Topisch anwendbare pharmazeutische zubereitung
DE60037313D1 (de) Pharmazeutische verbindungen
CY1105000T1 (el) Χρηση της σπινοσαδης ή μιας συνθεσεως περιεχουσης σπινοσαδη
DK1156790T3 (da) Kombinationer af formoterol og motetason furat
AR029175A1 (es) Derivados 2-amino-fenilpurina, un proceso para su preparacion, composicion farmaceutica que los comprende, y el uso de los mismos para la preparacion de un medicamento
EA200301165A1 (ru) Лекарственное средство на основе оксикодона
CY1106137T1 (el) Φαρμακευτικη συνθεση πepιλαμβανουσα λουμιρακοξιμπη
NO20034863L (no) Deutererte 3-piperidinopropiofenon så vel som legemidler som inneholder disse forbindelser
HUP0203716A2 (hu) Tumorellenes hatású szubsztituált (N-benzil-indol-3-il)-glioxilsav-származékok, ezeket tartalmazó gyógyszerkészítmények
IT1244636B (it) Uso dell'acetil l-carnitina nel trattamento terapeutico del coma e composizioni farmaceutiche utili in tale trattamento.
WO2003020214A3 (en) Bile-acid derived compounds for enhancing oral absorption and systemic bioavailability of drugs
ATE316788T1 (de) Medikament gegen pulmonale herzprobleme
CY1114250T1 (el) Ακετυλ l-καρνιτινη για την προληψη της επιπονης περιφερικης διαβητικης νευροπαθειας
CY1106510T1 (el) Φαρμακευτικα σκευασματα της λαβενδοϋστινης
UY25339A1 (es) Procedimiento para la preparacion de medicamentos conteniendo compuestos utilizados en el tratamiento del sindrome de la apnea del sueño.