CY1106287T1 - Απepιοριστα βλαστικα σωματικα κυτταρα που λαμβανονται απο αιμα ανθρωπινου ομφαλιου λωρου - Google Patents

Απepιοριστα βλαστικα σωματικα κυτταρα που λαμβανονται απο αιμα ανθρωπινου ομφαλιου λωρου

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Publication number
CY1106287T1
CY1106287T1 CY20061101781T CY061101781T CY1106287T1 CY 1106287 T1 CY1106287 T1 CY 1106287T1 CY 20061101781 T CY20061101781 T CY 20061101781T CY 061101781 T CY061101781 T CY 061101781T CY 1106287 T1 CY1106287 T1 CY 1106287T1
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CY
Cyprus
Prior art keywords
cord blood
umbilical cord
human umbilical
depiorized
cells derived
Prior art date
Application number
CY20061101781T
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English (en)
Inventor
Peter Wernet
Original Assignee
Kourion Therapeutics Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Kourion Therapeutics Ag filed Critical Kourion Therapeutics Ag
Publication of CY1106287T1 publication Critical patent/CY1106287T1/el

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/48—Reproductive organs
    • A61K35/54—Ovaries; Ova; Ovules; Embryos; Foetal cells; Germ cells
    • A61K35/545—Embryonic stem cells; Pluripotent stem cells; Induced pluripotent stem cells; Uncharacterised stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/48—Reproductive organs
    • A61K35/50—Placenta; Placental stem cells; Amniotic fluid; Amnion; Amniotic stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/48—Reproductive organs
    • A61K35/51—Umbilical cord; Umbilical cord blood; Umbilical stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0607—Non-embryonic pluripotent stem cells, e.g. MASC

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Reproductive Health (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Hematology (AREA)
  • Neurology (AREA)
  • Diabetes (AREA)
  • Wood Science & Technology (AREA)
  • Neurosurgery (AREA)
  • Gynecology & Obstetrics (AREA)
  • Microbiology (AREA)
  • Pregnancy & Childbirth (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Emergency Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)

Abstract

Περιγράφεται εδώ σύνθεση σε αίμα ανθρώπινου ομφάλιου λώρου και πλακούντος, που περιλαμβάνει απεριόριστα σωματικά βλαστικά κύτταρα, η οποία μπορεί να ενισχύεται in vitro προς μεγάλες ποσότητες επαρκείς για ιατρικές εφαρμογές σαν αναγεννητικά φάρμακα. Περιγράφεται έναρξη και συντήρηση, καθώς επίσης πρωτόκολλα ex vivo επέκτασης τέτοιων βλαστοκυττάρων από αίμα ομφάλιου λώρου. Περαιτέρω, δεικνύεται ότι από αυτά τα κύτταρα, χρησιμοποιώντας διάφορα πρωτόκολλα διέγερσης διαφοροποίησης διακριτής γράμμωσης, απόγονοι για αιματοποίηση και ενδοθήλιο, καθώς επίσης μεσεγχυματικοί απόγονοι για μη οστό, χόνδρο και λίπος, καθώς επίσης ουδέτεροι απόγονοι μπορεί να καλλιεργηθούν και να επεκταθούν για χρήση στην επαναδημιουργική ιατρική.
CY20061101781T 2000-11-03 2006-12-11 Απepιοριστα βλαστικα σωματικα κυτταρα που λαμβανονται απο αιμα ανθρωπινου ομφαλιου λωρου CY1106287T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US24516800P 2000-11-03 2000-11-03
PCT/EP2001/012768 WO2002036751A2 (en) 2000-11-03 2001-11-03 Human cord blood derived unrestricted somatic stem cells (ussc)

Publications (1)

Publication Number Publication Date
CY1106287T1 true CY1106287T1 (el) 2011-10-12

Family

ID=22925565

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20061101781T CY1106287T1 (el) 2000-11-03 2006-12-11 Απepιοριστα βλαστικα σωματικα κυτταρα που λαμβανονται απο αιμα ανθρωπινου ομφαλιου λωρου

Country Status (25)

Country Link
US (3) US7560280B2 (el)
EP (1) EP1404815B1 (el)
JP (2) JP4799804B2 (el)
CN (1) CN100480375C (el)
AT (1) ATE340255T1 (el)
AU (2) AU2953302A (el)
BG (1) BG107770A (el)
CA (1) CA2426987C (el)
CY (1) CY1106287T1 (el)
CZ (1) CZ20031165A3 (el)
DE (1) DE60123293T2 (el)
DK (1) DK1404815T3 (el)
EA (1) EA008619B1 (el)
EE (1) EE200300205A (el)
ES (1) ES2272563T3 (el)
HK (1) HK1071771A1 (el)
HU (1) HUP0301600A3 (el)
IL (2) IL155608A0 (el)
MX (1) MXPA03003844A (el)
NO (1) NO20031999L (el)
PL (1) PL362293A1 (el)
PT (1) PT1404815E (el)
SK (1) SK5242003A3 (el)
UA (1) UA81390C2 (el)
WO (1) WO2002036751A2 (el)

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