CY1106032T1 - Υποκατασταθεισες πυραζολες - Google Patents

Υποκατασταθεισες πυραζολες

Info

Publication number
CY1106032T1
CY1106032T1 CY20071100223T CY071100223T CY1106032T1 CY 1106032 T1 CY1106032 T1 CY 1106032T1 CY 20071100223 T CY20071100223 T CY 20071100223T CY 071100223 T CY071100223 T CY 071100223T CY 1106032 T1 CY1106032 T1 CY 1106032T1
Authority
CY
Cyprus
Prior art keywords
substituted pyrazoles
methods
pyrazoles
substituted
cathepsin
Prior art date
Application number
CY20071100223T
Other languages
English (en)
Inventor
J. Guy Breitenbucher
Hui Cai
James P. Edwards
Cheryl A. Grice
Darin J. Gustin
Haripada Khatuya
Steven P. Meduna
Barbara A. Pio
Kevin L. Tays
Jianmei Wei
Mary Pat Beavers
Original Assignee
Ortho-Mcneil Pharmaceutical, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ortho-Mcneil Pharmaceutical, Inc. filed Critical Ortho-Mcneil Pharmaceutical, Inc.
Publication of CY1106032T1 publication Critical patent/CY1106032T1/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Rheumatology (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Περιγράφονται υττοκατασταθείσες πυραζόλες, μέθοδοι παραγωγής τους, συνθέσεις που τις περιέχουν και μέθοδοι χρήσεως τους για την αγωγή, για παράδειγμα, αυτοάνοσων νόσων στις οποίες μεσολαβεί η καθεψίνη S.
CY20071100223T 2000-08-14 2007-02-20 Υποκατασταθεισες πυραζολες CY1106032T1 (el)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US22513800P 2000-08-14 2000-08-14
US09/928,122 US7309703B2 (en) 2000-08-14 2001-08-10 Substituted pyrazoles
PCT/US2001/025289 WO2002014314A2 (en) 2000-08-14 2001-08-10 Substituted pyrazoles

Publications (1)

Publication Number Publication Date
CY1106032T1 true CY1106032T1 (el) 2011-04-06

Family

ID=26919335

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20071100223T CY1106032T1 (el) 2000-08-14 2007-02-20 Υποκατασταθεισες πυραζολες

Country Status (17)

Country Link
US (9) US7309703B2 (el)
EP (1) EP1309591B1 (el)
JP (1) JP5140225B2 (el)
CN (1) CN1329392C (el)
AR (1) AR035714A1 (el)
AT (1) ATE352552T1 (el)
AU (2) AU2001281255B2 (el)
CA (1) CA2419540A1 (el)
CY (1) CY1106032T1 (el)
DE (1) DE60126286T2 (el)
DK (1) DK1309591T3 (el)
ES (1) ES2281434T3 (el)
HK (1) HK1052509B (el)
MX (1) MXPA03001421A (el)
NZ (1) NZ524193A (el)
PT (1) PT1309591E (el)
WO (1) WO2002014314A2 (el)

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Also Published As

Publication number Publication date
US7429591B2 (en) 2008-09-30
US20070004747A1 (en) 2007-01-04
US7417046B2 (en) 2008-08-26
CN1329392C (zh) 2007-08-01
EP1309591B1 (en) 2007-01-24
ES2281434T3 (es) 2007-10-01
US20070010530A1 (en) 2007-01-11
NZ524193A (en) 2004-12-24
HK1052509B (zh) 2007-09-07
EP1309591A2 (en) 2003-05-14
ATE352552T1 (de) 2007-02-15
US20070004755A1 (en) 2007-01-04
PT1309591E (pt) 2007-04-30
US20070004754A1 (en) 2007-01-04
US7772236B2 (en) 2010-08-10
HK1052509A1 (en) 2003-09-19
MXPA03001421A (es) 2004-01-26
CA2419540A1 (en) 2002-02-21
DK1309591T3 (da) 2007-03-26
US7589202B2 (en) 2009-09-15
US7452890B2 (en) 2008-11-18
JP5140225B2 (ja) 2013-02-06
US7388011B2 (en) 2008-06-17
DE60126286T2 (de) 2007-11-15
JP2004512272A (ja) 2004-04-22
DE60126286D1 (de) 2007-03-15
US20070004738A1 (en) 2007-01-04
US20080293732A1 (en) 2008-11-27
WO2002014314A2 (en) 2002-02-21
WO2002014314A3 (en) 2002-06-06
AU2001281255B2 (en) 2006-07-20
US20070021437A1 (en) 2007-01-25
AU8125501A (en) 2002-02-25
US7393850B2 (en) 2008-07-01
CN1468239A (zh) 2004-01-14
US20020040020A1 (en) 2002-04-04
US20080300255A1 (en) 2008-12-04
US7309703B2 (en) 2007-12-18
AR035714A1 (es) 2004-07-07

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