ATE312096T1 - Neue verbindungen - Google Patents

Neue verbindungen

Info

Publication number
ATE312096T1
ATE312096T1 AT02792158T AT02792158T ATE312096T1 AT E312096 T1 ATE312096 T1 AT E312096T1 AT 02792158 T AT02792158 T AT 02792158T AT 02792158 T AT02792158 T AT 02792158T AT E312096 T1 ATE312096 T1 AT E312096T1
Authority
AT
Austria
Prior art keywords
new connections
thienylsulphonamides
pyrazinyl
asthma
formula
Prior art date
Application number
AT02792158T
Other languages
English (en)
Inventor
Andrew Baxter
Timothy Johnson
Nicholas Kindon
Bryan Roberts
John Steele
Michael Stocks
Nicholas Tomkinson
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from SE0104474A external-priority patent/SE0104474D0/xx
Priority claimed from SE0202139A external-priority patent/SE0202139D0/xx
Application filed filed Critical
Application granted granted Critical
Publication of ATE312096T1 publication Critical patent/ATE312096T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D249/00Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/081,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
AT02792158T 2001-12-18 2002-12-17 Neue verbindungen ATE312096T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE0104474A SE0104474D0 (sv) 2001-12-18 2001-12-18 Novel Compounds
SE0202139A SE0202139D0 (sv) 2002-07-05 2002-07-05 Novel compounds
PCT/SE2002/002355 WO2003051870A1 (en) 2001-12-18 2002-12-17 Novel compounds

Publications (1)

Publication Number Publication Date
ATE312096T1 true ATE312096T1 (de) 2005-12-15

Family

ID=26655646

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02792158T ATE312096T1 (de) 2001-12-18 2002-12-17 Neue verbindungen

Country Status (7)

Country Link
US (1) US7410972B2 (de)
EP (1) EP1458715B1 (de)
JP (1) JP2005516936A (de)
AT (1) ATE312096T1 (de)
AU (1) AU2002358390A1 (de)
DE (1) DE60207890T2 (de)
WO (1) WO2003051870A1 (de)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI328007B (en) * 2002-01-16 2010-08-01 Astrazeneca Ab Novel compounds
DE10260003A1 (de) * 2002-12-20 2004-07-08 Zf Friedrichshafen Ag Radnabenantrieb
SE0301653D0 (sv) * 2003-06-05 2003-06-05 Astrazeneca Ab Novel compounds
SE0302304D0 (sv) * 2003-08-27 2003-08-27 Astrazeneca Ab Novel compounds
EP1661889A4 (de) * 2003-09-05 2009-08-05 Ono Pharmaceutical Co Chemokinrezeptorantagonist und dessen medizinische verwendung
US20080269249A2 (en) * 2004-12-27 2008-10-30 Alcon, Inc. Aminopyrazine analogs for treating glaucoma and other rho kinase-mediated diseases and conditions
EP2354126B1 (de) * 2005-01-14 2013-09-25 ChemoCentryx, Inc. Heteroarylsulfonamide und CCR2
US7622583B2 (en) 2005-01-14 2009-11-24 Chemocentryx, Inc. Heteroaryl sulfonamides and CCR2
TWI422376B (zh) 2005-01-25 2014-01-11 Synta Pharmaceuticals Corp 用於炎症及免疫相關用途之化合物
GB0514743D0 (en) * 2005-07-19 2005-08-24 Astrazeneca Ab Salt
TW200800921A (en) * 2005-09-19 2008-01-01 Astrazeneca Ab Novel compounds
EP1970373A1 (de) * 2005-12-02 2008-09-17 Mitsubishi Tanabe Pharma Corporation Alicyclische heterocyclische verbindung
US20090182142A1 (en) * 2005-12-02 2009-07-16 Shigeru Furukubo Aromatic Compound
TW200730512A (en) 2005-12-12 2007-08-16 Astrazeneca Ab Novel compounds
GB0526445D0 (en) * 2005-12-23 2006-02-08 Novartis Ag Organic compounds
BRPI0808013A2 (pt) * 2007-02-22 2014-06-17 Merck Serono Sa Compostos de quinoxalina e uso dos mesmos
BRPI0813695B8 (pt) 2007-07-12 2021-05-25 Chemocentryx Inc compostos de heteroaril piridil e fenil benzenossulfonamidas fundidas, composição, método de modular a função de ccr2, usos dos compostos e forma cristalina
EP2374802B1 (de) 2008-11-10 2014-04-23 Kyowa Hakko Kirin Co., Ltd. Inhibitor der kynureninproduktion
TWI535442B (zh) 2010-05-10 2016-06-01 Kyowa Hakko Kirin Co Ltd A nitrogen-containing heterocyclic compound having an action of inhibiting the production of canine erythritine
AU2011317675A1 (en) 2010-10-20 2013-05-02 Merck Serono S.A. Geneva Method for preparing substituted N-(3-amino-quinoxalin-2-yl)-sulfonamides and their intermediates N-(3-chloro-quinoxalin-2-yl)sulfonamides
EP3312173B1 (de) 2011-11-09 2021-12-22 Kyowa Kirin Co., Ltd. Stickstoffenthaltende heterocyclische verbindungen
MX360455B (es) * 2013-05-14 2018-11-01 Active Biotech Ab Derivados de n-(heteroaril)-sulfonamida utiles como inhibidores de s100.
IL294410B2 (en) 2016-11-23 2024-02-01 Chemocentryx Inc A method for the treatment of focal segmental tuberous sclerosis
AU2018347361A1 (en) 2017-10-11 2020-04-30 Chemocentryx, Inc. Treatment of focal segmental glomerulosclerosis with CCR2 antagonists

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5962490A (en) * 1987-09-25 1999-10-05 Texas Biotechnology Corporation Thienyl-, furyl- and pyrrolyl-sulfonamides and derivatives thereof that modulate the activity of endothelin
CA2162630C (en) * 1994-11-25 2007-05-01 Volker Breu Sulfonamides
WO2004007472A1 (ja) 2002-07-10 2004-01-22 Ono Pharmaceutical Co., Ltd. Ccr4アンタゴニストおよびその医薬用途

Also Published As

Publication number Publication date
JP2005516936A (ja) 2005-06-09
AU2002358390A1 (en) 2003-06-30
DE60207890T2 (de) 2006-08-10
US20050075346A1 (en) 2005-04-07
DE60207890D1 (de) 2006-01-12
WO2003051870A1 (en) 2003-06-26
EP1458715A1 (de) 2004-09-22
US7410972B2 (en) 2008-08-12
EP1458715B1 (de) 2005-12-07

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties