CU20170099A7 - Terapias de combinación para el tratamiento de cánceres - Google Patents
Terapias de combinación para el tratamiento de cánceresInfo
- Publication number
- CU20170099A7 CU20170099A7 CUP2017000099A CU20170099A CU20170099A7 CU 20170099 A7 CU20170099 A7 CU 20170099A7 CU P2017000099 A CUP2017000099 A CU P2017000099A CU 20170099 A CU20170099 A CU 20170099A CU 20170099 A7 CU20170099 A7 CU 20170099A7
- Authority
- CU
- Cuba
- Prior art keywords
- cancer treatment
- combination therapies
- methods
- entospletinib
- navitoclax
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Abstract
<p>Se proporcionan en el presente documento métodos que se relacionan con la estrategia<br /> terapéutica para el tratamiento del cáncer, incluyendo malignidades hematológicas. En particular, los<br /> métodos incluyen la administración de entospletinib y un inhibidor de Bcl-2, tal como venetoclax,<br /> navitoclax y ABT-737.<br /> </p>
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201562111604P | 2015-02-03 | 2015-02-03 | |
PCT/US2016/015727 WO2016126552A1 (en) | 2015-02-03 | 2016-01-29 | Combination therapies for treating cancers |
Publications (1)
Publication Number | Publication Date |
---|---|
CU20170099A7 true CU20170099A7 (es) | 2018-03-13 |
Family
ID=55398445
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CUP2017000099A CU20170099A7 (es) | 2015-02-03 | 2016-01-29 | Terapias de combinación para el tratamiento de cánceres |
Country Status (25)
Country | Link |
---|---|
US (2) | US20180117052A1 (es) |
EP (1) | EP3253385A1 (es) |
JP (1) | JP2018503653A (es) |
KR (1) | KR20170104616A (es) |
CN (1) | CN107205992A (es) |
AU (1) | AU2016215643A1 (es) |
BR (1) | BR112017016019A2 (es) |
CA (1) | CA2974828A1 (es) |
CL (1) | CL2017001943A1 (es) |
CO (1) | CO2017007662A2 (es) |
CR (1) | CR20170352A (es) |
CU (1) | CU20170099A7 (es) |
EA (1) | EA201791516A1 (es) |
EC (1) | ECSP17048849A (es) |
GT (1) | GT201700167A (es) |
IL (1) | IL253573A0 (es) |
MA (1) | MA41449A (es) |
MD (1) | MD20170073A2 (es) |
MX (1) | MX2017009724A (es) |
PE (1) | PE20171241A1 (es) |
PH (1) | PH12017550063A1 (es) |
SG (1) | SG11201706107SA (es) |
SV (1) | SV2017005489A (es) |
TW (1) | TW201639573A (es) |
WO (1) | WO2016126552A1 (es) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102307581B (zh) | 2008-12-08 | 2016-08-17 | 吉利德康涅狄格股份有限公司 | 咪唑并哌嗪syk抑制剂 |
US9562056B2 (en) | 2010-03-11 | 2017-02-07 | Gilead Connecticut, Inc. | Imidazopyridines Syk inhibitors |
US20160168155A1 (en) * | 2013-07-30 | 2016-06-16 | Gilead Connecticut, Inc. | Polymorph of syk inhibitors |
AU2014296184B2 (en) | 2013-07-31 | 2017-04-27 | Gilead Sciences, Inc. | Syk inhibitors |
WO2015084992A1 (en) | 2013-12-04 | 2015-06-11 | Gilead Sciences, Inc. | Methods for treating cancers |
UY35898A (es) | 2013-12-23 | 2015-07-31 | Gilead Sciences Inc | ?compuestos inhibidores de syk y composiciones que los comprenden?. |
JP6310144B2 (ja) | 2014-07-14 | 2018-04-18 | ギリアード サイエンシーズ, インコーポレイテッド | がんを処置するための組み合わせ |
TWI808055B (zh) | 2016-05-11 | 2023-07-11 | 美商滬亞生物國際有限公司 | Hdac 抑制劑與 pd-1 抑制劑之組合治療 |
TWI794171B (zh) | 2016-05-11 | 2023-03-01 | 美商滬亞生物國際有限公司 | Hdac抑制劑與pd-l1抑制劑之組合治療 |
US10759798B2 (en) * | 2016-09-14 | 2020-09-01 | Hangzhou Solipharma Co., Ltd. | ABT-199 addition salt and crystal form thereof, preparation method thereof, and pharmaceutical composition thereof |
EP3512519A1 (en) | 2016-09-14 | 2019-07-24 | Gilead Sciences, Inc. | Syk inhibitors |
WO2018200841A1 (en) * | 2017-04-28 | 2018-11-01 | Actinium Pharmaceuticals, Inc. | Method for treating cancer using a bcl-2 inhibitor in conjunction with an alpha-emitting radioimmunotherapeutic |
CN115028640A (zh) | 2017-08-25 | 2022-09-09 | 吉利德科学公司 | Syk抑制剂的多晶型物 |
JP2021510165A (ja) | 2018-01-10 | 2021-04-15 | リキュリウム アイピー ホールディングス リミテッド ライアビリティー カンパニー | ベンズアミド化合物 |
JP2022521413A (ja) | 2019-02-22 | 2022-04-07 | クロノス バイオ インコーポレイテッド | Syk阻害剤としての縮合ピラジンの固体形態 |
SG11202113356XA (en) | 2019-06-12 | 2021-12-30 | Juno Therapeutics Inc | Combination therapy of a cell-mediated cytotoxic therapy and an inhibitor of a prosurvival bcl2 family protein |
EP4069233A4 (en) * | 2019-12-04 | 2024-03-13 | Ascentage Pharma Suzhou Co Ltd | PHARMACEUTICAL COMBINATION AND USE THEREOF |
WO2022133030A1 (en) | 2020-12-16 | 2022-06-23 | Juno Therapeutics, Inc. | Combination therapy of a cell therapy and a bcl2 inhibitor |
AU2022255990A1 (en) * | 2021-04-05 | 2023-10-26 | Pinotbio, Inc. | Combined therapy of 4'-thio-5-aza-2'-deoxycytidine and venetoclax |
WO2023220655A1 (en) | 2022-05-11 | 2023-11-16 | Celgene Corporation | Methods to overcome drug resistance by re-sensitizing cancer cells to treatment with a prior therapy via treatment with a t cell therapy |
Family Cites Families (39)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4965288A (en) | 1988-02-25 | 1990-10-23 | Merrell Dow Pharmaceuticals Inc. | Inhibitors of lysyl oxidase |
US5059714A (en) | 1988-02-25 | 1991-10-22 | Merrell Dow Pharmaceuticals Inc. | Inhibitors of lysyl oxidase |
US5021456A (en) | 1988-02-25 | 1991-06-04 | Merrell Dow Pharmaceuticals Inc. | Inhibitors of lysyl oxidase |
US5252608A (en) | 1988-02-25 | 1993-10-12 | Merrell Dow Pharmaceuticals Inc. | Inhibitors of lysyl oxidase |
US4943593A (en) | 1988-02-25 | 1990-07-24 | Merrell Dow Pharmaceuticals Inc. | Inhibitors of lysyl oxidase |
US5182297A (en) | 1988-02-25 | 1993-01-26 | Merrell Dow Pharmaceuticals Inc. | Inhibitors of lysyl oxidase |
US5120764A (en) | 1988-11-01 | 1992-06-09 | Merrell Dow Pharmaceuticals Inc. | Inhibitors of lysyl oxidase |
US4997854A (en) | 1989-08-25 | 1991-03-05 | Trustees Of Boston University | Anti-fibrotic agents and methods for inhibiting the activity of lysyl oxidase in-situ using adjacently positioned diamine analogue substrates |
FR2828206B1 (fr) | 2001-08-03 | 2004-09-24 | Centre Nat Rech Scient | Utilisation d'inhibiteurs des lysyl oxydases pour la culture cellulaire et le genie tissulaire |
US7973161B2 (en) | 2003-11-13 | 2011-07-05 | Abbott Laboratories | Apoptosis promoters |
US7932260B2 (en) | 2004-05-13 | 2011-04-26 | Icos Corporation | Quinazolinones as inhibitors of human phosphatidylinositol 3-kinase delta |
US20090142345A1 (en) | 2005-03-15 | 2009-06-04 | Takeda Pharmaceutical Company Limited | Prophylactic/therapeutic agent for cancer |
PT1888550E (pt) | 2005-05-12 | 2014-09-03 | Abbvie Bahamas Ltd | Promotores de apoptose |
EP2537529B1 (en) | 2007-08-02 | 2018-10-17 | Gilead Biologics, Inc. | Loxl2 inhibitory antibodies and uses thereof |
US8652843B2 (en) | 2008-08-12 | 2014-02-18 | Oncomed Pharmaceuticals, Inc. | DDR1-binding agents and methods of use thereof |
TWI478922B (zh) * | 2008-12-08 | 2015-04-01 | Gilead Connenticut Inc | 作為脾臟酪胺酸激酶(Syk)抑制劑之咪唑並吡化合物 |
US8450321B2 (en) * | 2008-12-08 | 2013-05-28 | Gilead Connecticut, Inc. | 6-(1H-indazol-6-yl)-N-[4-(morpholin-4-yl)phenyl]imidazo-[1,2-A]pyrazin-8-amine, or a pharmaceutically acceptable salt thereof, as a SYK inhibitor |
US8362013B2 (en) | 2009-04-30 | 2013-01-29 | Abbvie Inc. | Salt of ABT-263 and solid-state forms thereof |
US8546399B2 (en) | 2009-05-26 | 2013-10-01 | Abbvie Inc. | Apoptosis inducing agents for the treatment of cancer and immune and autoimmune diseases |
TWI598347B (zh) | 2009-07-13 | 2017-09-11 | 基利科學股份有限公司 | 調節細胞凋亡信號之激酶的抑制劑 |
CN102695702A (zh) | 2009-09-20 | 2012-09-26 | 雅培制药有限公司 | 用于治疗bcl-2蛋白相关疾病的abt-263晶体形式和溶剂化物 |
CN103370080A (zh) | 2010-02-04 | 2013-10-23 | 吉联亚生物科技有限公司 | 结合赖氨酰氧化酶样2(loxl2)的抗体和其使用方法 |
WO2011133668A2 (en) * | 2010-04-20 | 2011-10-27 | President And Fellows Of Harvard College | Methods and compositions for the treatment of cancer |
PE20131376A1 (es) | 2010-08-27 | 2013-11-25 | Gilead Biologics Inc | Anticuerpos para metaloproteinasa-9 de matriz |
US8722657B2 (en) | 2010-11-23 | 2014-05-13 | Abbvie Inc. | Salts and crystalline forms of an apoptosis-inducing agent |
WO2013027802A1 (ja) | 2011-08-23 | 2013-02-28 | 中外製薬株式会社 | 抗腫瘍活性を有する新規な抗ddr1抗体 |
GB201115529D0 (en) | 2011-09-08 | 2011-10-26 | Imp Innovations Ltd | Antibodies, uses and methods |
CN104024257A (zh) | 2011-10-04 | 2014-09-03 | 吉利德卡利斯托加有限责任公司 | Pi3k的新的喹喔啉抑制剂 |
UY34573A (es) | 2012-01-27 | 2013-06-28 | Gilead Sciences Inc | Inhibidor de la quinasa que regula la señal de la apoptosis |
WO2013116562A1 (en) | 2012-02-03 | 2013-08-08 | Gilead Calistoga Llc | Compositions and methods of treating a disease with (s)-4 amino-6-((1-(5-chloro-4-oxo-3-phenyl-3,4-dihydroquinazolin-2-yl)ethyl)amino)pyrimidine-5-carbonitrile |
CA2882134A1 (en) * | 2012-08-14 | 2014-02-20 | Gilead Calistoga Llc | Combination therapies for treating cancer |
JP6408993B2 (ja) * | 2012-09-07 | 2018-10-17 | ジェネンテック, インコーポレイテッド | タイプII抗CD20抗体と選択的Bcl−2インヒビターの併用療法 |
AR092662A1 (es) | 2012-09-24 | 2015-04-29 | Gilead Sciences Inc | Anticuerpos anti-ddr1 |
JP6207100B2 (ja) | 2012-12-21 | 2017-10-04 | ギリアード カリストガ エルエルシー | イソキノリノンまたはキナゾリノンホスファチジルイノシトール3−キナーゼ阻害剤 |
CA2895782C (en) | 2012-12-21 | 2017-08-22 | Gilead Calistoga Llc | Substituted pyrimidine aminoalkyl-quinazolones as phosphatidylinositol 3-kinase inhibitors |
NZ714710A (en) | 2013-06-14 | 2016-11-25 | Gilead Sciences Inc | Phosphatidylinositol 3-kinase inhibitors |
MD4684B1 (ro) | 2013-07-30 | 2020-03-31 | Gilead Connecticut INc. | Formulări pe bază de imidazopirazine în calitate de inhibitori SYK |
US20160168155A1 (en) | 2013-07-30 | 2016-06-16 | Gilead Connecticut, Inc. | Polymorph of syk inhibitors |
EP2886146A1 (en) * | 2013-12-20 | 2015-06-24 | Sanofi-Aventis Deutschland GmbH | Needle safety device and drug delivery device |
-
2016
- 2016-01-21 TW TW105101876A patent/TW201639573A/zh unknown
- 2016-01-28 MA MA041449A patent/MA41449A/fr unknown
- 2016-01-29 MD MDA20170073A patent/MD20170073A2/ro not_active Application Discontinuation
- 2016-01-29 MX MX2017009724A patent/MX2017009724A/es unknown
- 2016-01-29 US US15/548,401 patent/US20180117052A1/en not_active Abandoned
- 2016-01-29 SG SG11201706107SA patent/SG11201706107SA/en unknown
- 2016-01-29 EP EP16705384.2A patent/EP3253385A1/en not_active Withdrawn
- 2016-01-29 CN CN201680007860.5A patent/CN107205992A/zh active Pending
- 2016-01-29 WO PCT/US2016/015727 patent/WO2016126552A1/en active Application Filing
- 2016-01-29 JP JP2017539623A patent/JP2018503653A/ja active Pending
- 2016-01-29 EA EA201791516A patent/EA201791516A1/ru unknown
- 2016-01-29 AU AU2016215643A patent/AU2016215643A1/en not_active Abandoned
- 2016-01-29 BR BR112017016019A patent/BR112017016019A2/pt not_active Application Discontinuation
- 2016-01-29 CU CUP2017000099A patent/CU20170099A7/es unknown
- 2016-01-29 KR KR1020177023454A patent/KR20170104616A/ko not_active Application Discontinuation
- 2016-01-29 CA CA2974828A patent/CA2974828A1/en not_active Abandoned
- 2016-01-29 PE PE2017001282A patent/PE20171241A1/es not_active Application Discontinuation
- 2016-01-29 CR CR20170352A patent/CR20170352A/es unknown
- 2016-01-29 US US15/010,906 patent/US20160220573A1/en not_active Abandoned
-
2017
- 2017-07-19 IL IL253573A patent/IL253573A0/en unknown
- 2017-07-27 GT GT201700167A patent/GT201700167A/es unknown
- 2017-07-28 SV SV2017005489A patent/SV2017005489A/es unknown
- 2017-07-28 EC ECIEPI201748849A patent/ECSP17048849A/es unknown
- 2017-07-28 CO CONC2017/0007662A patent/CO2017007662A2/es unknown
- 2017-07-28 CL CL2017001943A patent/CL2017001943A1/es unknown
- 2017-07-31 PH PH12017550063A patent/PH12017550063A1/en unknown
Also Published As
Publication number | Publication date |
---|---|
PH12017550063A1 (en) | 2018-02-05 |
EP3253385A1 (en) | 2017-12-13 |
ECSP17048849A (es) | 2017-10-31 |
CR20170352A (es) | 2017-09-29 |
US20160220573A1 (en) | 2016-08-04 |
PE20171241A1 (es) | 2017-08-24 |
US20180117052A1 (en) | 2018-05-03 |
WO2016126552A1 (en) | 2016-08-11 |
EA201791516A1 (ru) | 2018-01-31 |
SG11201706107SA (en) | 2017-08-30 |
AU2016215643A1 (en) | 2017-08-10 |
TW201639573A (zh) | 2016-11-16 |
CL2017001943A1 (es) | 2018-03-02 |
CN107205992A (zh) | 2017-09-26 |
JP2018503653A (ja) | 2018-02-08 |
MX2017009724A (es) | 2017-11-17 |
SV2017005489A (es) | 2017-10-17 |
BR112017016019A2 (pt) | 2018-03-20 |
IL253573A0 (en) | 2017-09-28 |
CA2974828A1 (en) | 2016-08-11 |
CO2017007662A2 (es) | 2017-10-20 |
KR20170104616A (ko) | 2017-09-15 |
GT201700167A (es) | 2017-11-02 |
MD20170073A2 (ro) | 2018-02-28 |
MA41449A (fr) | 2017-12-12 |
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