CS241104B2 - Method of alpha-arylalkane acid production - Google Patents

Method of alpha-arylalkane acid production Download PDF

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Publication number
CS241104B2
CS241104B2 CS823100A CS310082A CS241104B2 CS 241104 B2 CS241104 B2 CS 241104B2 CS 823100 A CS823100 A CS 823100A CS 310082 A CS310082 A CS 310082A CS 241104 B2 CS241104 B2 CS 241104B2
Authority
CS
Czechoslovakia
Prior art keywords
alpha
acid
ester
mixture
water
Prior art date
Application number
CS823100A
Other languages
Czech (cs)
English (en)
Other versions
CS310082A2 (en
Inventor
George Ch Schloemer
Original Assignee
Syntex Pharma Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syntex Pharma Int filed Critical Syntex Pharma Int
Publication of CS310082A2 publication Critical patent/CS310082A2/cs
Publication of CS241104B2 publication Critical patent/CS241104B2/cs

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/09—Preparation of carboxylic acids or their salts, halides or anhydrides from carboxylic acid esters or lactones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/63—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by introduction of halogen; by substitution of halogen atoms by other halogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
    • C07C41/48—Preparation of compounds having groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/27—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation
    • C07C45/29—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation of hydroxy groups
    • C07C45/292—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation of hydroxy groups with chromium derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
    • C07C45/46—Friedel-Crafts reactions
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/84—Ketones containing a keto group bound to a six-membered aromatic ring containing ether groups, groups, groups, or groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/30—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Cosmetics (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CS823100A 1981-04-30 1982-04-29 Method of alpha-arylalkane acid production CS241104B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US25911981A 1981-04-30 1981-04-30

Publications (2)

Publication Number Publication Date
CS310082A2 CS310082A2 (en) 1985-07-16
CS241104B2 true CS241104B2 (en) 1986-03-13

Family

ID=22983610

Family Applications (1)

Application Number Title Priority Date Filing Date
CS823100A CS241104B2 (en) 1981-04-30 1982-04-29 Method of alpha-arylalkane acid production

Country Status (21)

Country Link
EP (1) EP0064394A1 (es)
JP (1) JPS57192325A (es)
KR (1) KR890002772B1 (es)
AU (1) AU8313382A (es)
CA (1) CA1199646A (es)
CS (1) CS241104B2 (es)
DD (1) DD202688A5 (es)
DK (1) DK192982A (es)
ES (2) ES511816A0 (es)
FI (1) FI821501A0 (es)
GR (1) GR75425B (es)
HU (1) HU189577B (es)
IL (1) IL65629A (es)
IN (1) IN155753B (es)
NO (3) NO821417L (es)
NZ (1) NZ200458A (es)
PH (1) PH24244A (es)
PL (1) PL139818B1 (es)
PT (1) PT74818B (es)
RO (1) RO83840B1 (es)
ZA (1) ZA822955B (es)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ198271A (en) * 1980-09-11 1985-05-31 Syntex Pharma Int Preparation of alpha-aromatic-substituted alkanoic acids and intermediates
FI82680C (fi) * 1981-12-11 1991-04-10 Syntex Pharma Int Framstaellning av - arylalkansyror.
EP0151817B1 (en) * 1984-02-02 1986-12-03 ZAMBON S.p.A. Process for preparing alpha-arylalkanoic acids
IT1173216B (it) * 1984-02-03 1987-06-18 Zambon Spa Processo per la preparazione di acidi alfa-idrossiaril-alcanoici
IT1196013B (it) * 1984-02-03 1988-11-10 Zambon Spa Procedimento per preparare acidi alfa-aril-alcanoici
EP0160241B1 (en) * 1984-04-14 1988-11-30 Kyowa Hakko Kogyo Co., Ltd. Process for producing an alpha-aromatic group substituted alkanoic acid derivative
US4608441A (en) * 1984-07-11 1986-08-26 Blaschim S.P.A. Process for the preparation of arylalkanoic acids by oxidative rearrangement of arylalkanones
IT1201443B (it) * 1985-07-31 1989-02-02 Zambon Spa Intermedi per la sintesi di acidi carbossilici
JPS62263153A (ja) * 1986-05-28 1987-11-16 エフ・ホフマン―ラ　ロシユ　アーゲー カルバゾ−ル誘導体
IT1197800B (it) * 1986-08-01 1988-12-06 Zambon Spa Processo per la sintesi di acidi carbossilici
US4761497A (en) * 1987-10-13 1988-08-02 Eastman Kodak Company Process for preparing 2-naphthanoic acids and esters thereof
IT1251958B (it) * 1991-10-18 1995-05-27 Zambon Spa Processo per la dealogenazione di derivati del naftalene
JP3744060B2 (ja) * 1996-06-20 2006-02-08 ダイソー株式会社 アシルオキシスルホン酸エステル誘導体の製造法
ES2797777T3 (es) * 2017-04-24 2020-12-03 Igm Group B V Funcionalización oxidante simple de alquil aril cetonas
CN114644554A (zh) * 2020-12-21 2022-06-21 上海医药工业研究院 (s)-氟比洛芬的制备方法及其中间体

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE50898B1 (en) * 1980-02-26 1986-08-06 Blaschim Spa Process for preparing esters of 2-(6'-methoxy-2'-naphthyl)-propionic acid via rearrangement of new ketals of 2-halo-1-(6'-methoxy-2'-naphthyl)-propan-1-one
NZ198271A (en) * 1980-09-11 1985-05-31 Syntex Pharma Int Preparation of alpha-aromatic-substituted alkanoic acids and intermediates
JPS5798232A (en) * 1980-11-10 1982-06-18 Sagami Chem Res Center 1-(6-methoxy-2-naphthyl)-2-oxy-1-alkanone acetal
JPS57144234A (en) * 1981-03-03 1982-09-06 Sagami Chem Res Center 1-halophenyl-2-oxy-1-alkanone acetal

Also Published As

Publication number Publication date
HU189577B (en) 1986-07-28
DD202688A5 (de) 1983-09-28
RO83840B1 (ro) 1984-04-30
ES8401007A1 (es) 1983-12-01
EP0064394A1 (en) 1982-11-10
FI821501A0 (fi) 1982-04-29
IN155753B (es) 1985-03-02
PT74818B (en) 1983-10-28
AU8313382A (en) 1982-11-04
ES511816A0 (es) 1983-12-01
ES8601839A1 (es) 1985-12-01
ES524528A0 (es) 1985-12-01
CA1199646A (en) 1986-01-21
CS310082A2 (en) 1985-07-16
KR830010036A (ko) 1983-12-24
IL65629A (en) 1987-08-31
RO83840A2 (ro) 1984-04-02
PH24244A (en) 1990-05-04
PL139818B1 (en) 1987-02-28
JPS57192325A (en) 1982-11-26
NO824255L (no) 1982-11-01
GR75425B (es) 1984-07-17
NO821417L (no) 1982-11-01
PT74818A (en) 1982-05-01
IL65629A0 (en) 1982-07-30
KR890002772B1 (ko) 1989-07-28
DK192982A (da) 1982-10-31
PL236221A1 (es) 1982-12-06
NO831338L (no) 1982-11-01
NZ200458A (en) 1985-11-08
ZA822955B (en) 1983-12-28

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