CS207671B2 - Method of making the piperazinylchinazoline derivatives - Google Patents

Method of making the piperazinylchinazoline derivatives Download PDF

Info

Publication number: CS207671B2
Authority: CS; Czechoslovakia
Prior art keywords: carbon atoms; formula; group; different; alkoxy
Prior art date: 1977-11-05

Application number

CS787166A

Other languages

Czech (cs)

English (en)

Inventor

Simon F Campbell

Original Assignee

Pfizer

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1977-11-05

Filing date

1978-11-02

Publication date

1981-08-31

1978-11-02 Application filed by Pfizer filed Critical Pfizer

1980-02-20 Priority to CS801183A priority Critical patent/CS207672B2/cs

1981-08-31 Publication of CS207671B2 publication Critical patent/CS207671B2/cs

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
- C07D319/14—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
- C07D319/16—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D319/20—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring with substituents attached to the hetero ring
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/95—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Cardiology (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Heart & Thoracic Surgery (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

CS787166A 1977-11-05 1978-11-02 Method of making the piperazinylchinazoline derivatives CS207671B2 (en)

Priority Applications (1)

Application Number	Priority Date	Filing Date	Title
CS801183A CS207672B2 (cs)	1977-11-05	1980-02-20	Způsob výroby piperazinylchinazolinových derivátů

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB4612877		1977-11-05

Publications (1)

Publication Number	Publication Date
CS207671B2 true CS207671B2 (en)	1981-08-31

Family

ID=10439957

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
CS787166A CS207671B2 (en)	1977-11-05	1978-11-02	Method of making the piperazinylchinazoline derivatives
CS913544A CS354491A3 (en)	1977-11-05	1991-11-22	4-amino-2-/piperazin-1-yl/ or /homopiperazin-1-yl/quinazoline derivatives, process of their preparation and use

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
CS913544A CS354491A3 (en)	1977-11-05	1991-11-22	4-amino-2-/piperazin-1-yl/ or /homopiperazin-1-yl/quinazoline derivatives, process of their preparation and use

Country Status (36)

Country	Link
JP (1)	JPS5498792A (da)
AR (2)	AR219562A1 (da)
AT (1)	AT365186B (da)
AU (1)	AU509329B2 (da)
BE (1)	BE871771A (da)
CA (1)	CA1088059A (da)
CH (1)	CH643255A5 (da)
CS (2)	CS207671B2 (da)
DD (1)	DD139850A5 (da)
DE (1)	DE2847623C2 (da)
DK (1)	DK154082C (da)
EG (1)	EG13594A (da)
ES (2)	ES474805A1 (da)
FI (1)	FI64366C (da)
FR (1)	FR2407929A1 (da)
GR (1)	GR81514B (da)
HK (1)	HK94284A (da)
HU (1)	HU176306B (da)
IE (1)	IE47888B1 (da)
IL (1)	IL55857A (da)
IN (1)	IN148828B (da)
IT (1)	IT1100919B (da)
KE (1)	KE3350A (da)
LU (2)	LU80470A1 (da)
MY (1)	MY8500286A (da)
NL (2)	NL174549C (da)
NO (1)	NO150158C (da)
NZ (1)	NZ188813A (da)
PH (1)	PH13966A (da)
PL (2)	PL119419B1 (da)
PT (1)	PT68735A (da)
SE (1)	SE437518B (da)
SU (1)	SU816403A3 (da)
UA (1)	UA8324A1 (da)
YU (2)	YU40204B (da)
ZA (1)	ZA786184B (da)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1985004658A1 (en) *	1984-04-04	1985-10-24	Takeda Chemical Industries, Ltd.	1,5-benzoxathiepine derivatives and their preparation
WO1985002617A1 (en) *	1983-12-14	1985-06-20	Takeda Chemical Industries. Ltd.	1,5-benzoxathiepin derivatives and process for their preparation
WO1986002644A1 (en) *	1984-11-01	1986-05-09	Takeda Chemical Industries, Ltd.	1,5-benzoxathiepin derivatives and process for their preparation
EP0849265A1 (de) *	1996-12-20	1998-06-24	HEUMANN PHARMA GmbH	Neue polymorphe Form von Doxazosin-Mesylat (Form II)
EP0849264A1 (de) *	1996-12-20	1998-06-24	HEUMANN PHARMA GmbH	Neue polymorphe Form von doxazosinmesylat (Form I)
ES2282997T3 (es) *	1996-12-20	2007-10-16	Heumann Pcs Gmbh	Nueva forma polimorfa de mesilato e doxazosina (forma iii).
TW448155B (en) *	1999-03-29	2001-08-01	Dev Center Biotechnology	Method for producing amide compounds and quinazolin derivatives
EP1403263B1 (en) *	2002-09-27	2005-06-22	Council of Scientific and Industrial Research	Process for the preparation of N-(2,3-dihydrobenzo 1,4 dioxin-2-carbonyl) piperazine

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3663706A (en) *	1969-09-29	1972-05-16	Pfizer	Use of 2,4-diaminoquinazolines as hypotensive agents
US3669968A (en) *	1970-05-21	1972-06-13	Pfizer	Trialkoxy quinazolines

1978
- 1978-09-27 DK DK428678A patent/DK154082C/da active
- 1978-10-03 IN IN712/DEL/78A patent/IN148828B/en unknown
- 1978-10-24 CA CA314,027A patent/CA1088059A/en not_active Expired
- 1978-10-24 PH PH21726A patent/PH13966A/en unknown
- 1978-10-31 UA UA2679598A patent/UA8324A1/uk unknown
- 1978-10-31 SU SU782679598A patent/SU816403A3/ru active
- 1978-11-02 NZ NZ188813A patent/NZ188813A/xx unknown
- 1978-11-02 CS CS787166A patent/CS207671B2/cs unknown
- 1978-11-02 YU YU2553/78A patent/YU40204B/xx unknown
- 1978-11-02 ZA ZA00786184A patent/ZA786184B/xx unknown
- 1978-11-02 DE DE2847623A patent/DE2847623C2/de not_active Expired
- 1978-11-02 JP JP13569578A patent/JPS5498792A/ja active Granted
- 1978-11-02 SE SE7811382A patent/SE437518B/sv not_active IP Right Cessation
- 1978-11-02 AR AR274321A patent/AR219562A1/es active
- 1978-11-02 CH CH1132178A patent/CH643255A5/de not_active IP Right Cessation
- 1978-11-02 AT AT0784378A patent/AT365186B/de not_active IP Right Cessation
- 1978-11-02 HU HU78PI648A patent/HU176306B/hu unknown
- 1978-11-02 NL NLAANVRAGE7810909,A patent/NL174549C/xx not_active IP Right Cessation
- 1978-11-02 GR GR57562A patent/GR81514B/el unknown
- 1978-11-02 PT PT68735A patent/PT68735A/pt unknown
- 1978-11-02 FI FI783347A patent/FI64366C/fi not_active IP Right Cessation
- 1978-11-02 IL IL55857A patent/IL55857A/xx unknown
- 1978-11-03 NO NO783705A patent/NO150158C/no unknown
- 1978-11-03 LU LU80470A patent/LU80470A1/fr unknown
- 1978-11-03 DD DD78208868A patent/DD139850A5/de unknown
- 1978-11-03 PL PL1978216980A patent/PL119419B1/pl unknown
- 1978-11-03 ES ES474805A patent/ES474805A1/es not_active Expired
- 1978-11-03 FR FR7831126A patent/FR2407929A1/fr active Granted
- 1978-11-03 IT IT29434/78A patent/IT1100919B/it active Protection Beyond IP Right Term
- 1978-11-03 PL PL1978210681A patent/PL119586B1/pl unknown
- 1978-11-03 AU AU41322/78A patent/AU509329B2/en not_active Expired
- 1978-11-03 IE IE2179/78A patent/IE47888B1/en active Protection Beyond IP Right Term
- 1978-11-03 BE BE191544A patent/BE871771A/xx not_active IP Right Cessation
- 1978-11-04 EG EG641/78A patent/EG13594A/xx active
1979
- 1979-04-30 ES ES480121A patent/ES8308559A1/es not_active Expired
- 1979-10-18 AR AR278545A patent/AR223015A1/es active
1983
- 1983-02-17 YU YU386/83A patent/YU40419B/xx unknown
- 1983-11-21 KE KE3350A patent/KE3350A/xx unknown
1984
- 1984-11-29 HK HK942/84A patent/HK94284A/xx not_active IP Right Cessation
1985
- 1985-12-30 MY MY286/85A patent/MY8500286A/xx unknown
1991
- 1991-11-22 CS CS913544A patent/CS354491A3/cs unknown
1993
- 1993-06-11 NL NL930062C patent/NL930062I2/nl unknown
- 1993-06-24 LU LU88331C patent/LU88331I2/fr unknown

Also Published As

Publication number	Publication date
IL55857A0 (en)	1979-01-31
FI64366C (fi)	1983-11-10
IE47888B1 (en)	1984-07-11
JPS5625233B2 (da)	1981-06-11
EG13594A (en)	1982-03-31
AU4132278A (en)	1979-05-17
PH13966A (en)	1980-11-12
SE437518B (sv)	1985-03-04
BE871771A (fr)	1979-05-03
NO150158C (no)	1984-08-29
NL174549B (nl)	1984-02-01
DE2847623A1 (de)	1979-05-23
HU176306B (en)	1981-01-28
DK154082B (da)	1988-10-10
IT1100919B (it)	1985-09-28
NL930062I2 (nl)	1993-11-16
FI783347A (fi)	1979-05-06
CA1088059A (en)	1980-10-21
SE7811382L (sv)	1979-05-06
CH643255A5 (en)	1984-05-30
IL55857A (en)	1982-07-30
AT365186B (de)	1981-12-28
IN148828B (da)	1981-06-27
NO783705L (no)	1979-05-08
PL119586B1 (en)	1982-01-30
YU40204B (en)	1985-08-31
FR2407929A1 (fr)	1979-06-01
SU816403A3 (ru)	1981-03-23
YU38683A (en)	1983-06-30
ES480121A0 (es)	1980-07-16
HK94284A (en)	1984-12-07
FR2407929B1 (da)	1981-02-27
NZ188813A (en)	1980-10-08
FI64366B (fi)	1983-07-29
DK154082C (da)	1989-02-27
AR219562A1 (es)	1980-08-29
NO150158B (no)	1984-05-21
KE3350A (en)	1983-12-16
DE2847623C2 (de)	1983-06-01
ES8308559A1 (es)	1980-07-16
IE782179L (en)	1979-05-05
ZA786184B (en)	1979-10-31
NL7810909A (nl)	1979-05-08
LU80470A1 (fr)	1980-06-05
YU255378A (en)	1983-06-30
NL174549C (nl)	1984-07-02
NL930062I1 (nl)	1993-09-01
MY8500286A (en)	1985-12-31
LU88331I2 (fr)	1994-05-04
UA8324A1 (uk)	1996-03-29
AU509329B2 (en)	1980-05-08
DD139850A5 (de)	1980-01-23
CS354491A3 (en)	1992-06-17
PL210681A1 (da)	1979-11-05
GR81514B (da)	1984-12-11
PL119419B1 (en)	1981-12-31
YU40419B (en)	1985-12-31
DK428678A (da)	1979-05-06
AR223015A1 (es)	1981-07-15
IT7829434A0 (it)	1978-11-03
JPS5498792A (en)	1979-08-03
ES474805A1 (es)	1980-01-16
PT68735A (en)	1978-12-01
ATA784378A (de)	1981-05-15

Publication	Publication Date	Title
US4675319A (en)	1987-06-23	Antianaphylactic and antibronchospastic piperazinyl-(N-substituted phenyl)carboxamides, compositions and use
MXPA03001337A (es)	2005-06-30	Preparacion de risperidona.
EP0198456B1 (en)	1992-06-10	1,7-naphthyridine derivatives and medicinal preparations containing same
US3810896A (en)	1974-05-14	Flavonyloxyalkyl-piperazine compounds
EP0270926B1 (en)	1993-03-17	Agents promoting the activity of some antitumor agents and methods for their production
IE51551B1 (en)	1987-01-07	Isoquinoline derivatives,process for their preparation and pharmaceutical formulations containing them and their use
CS207671B2 (en)	1981-08-31	Method of making the piperazinylchinazoline derivatives
US4478837A (en)	1984-10-23	3-Hydrazino cycloalkyl[c]pyridazines as antihypertensive agents
JPH0434549B2 (da)	1992-06-08
GB1568398A (en)	1980-05-29	Triazolo pyridazine derivatives
HU180998B (en)	1983-05-30	Process for preparing new 5,11-dihydro-6h-pyrido/2,3-b/ /1,4/-benzodiazepin-6-ones substituted in position 11
US3301855A (en)	1967-01-31	Derivatives of 4-nu-(2-nu, nu-dimethylaminolower alkyl)-amino quinazoline
AU619344B2 (en)	1992-01-23	Tetrahydronaphthalene and indane derivatives
US4775673A (en)	1988-10-04	Substituted acylpiperazinoquinazolines and pharmaceutical compositions containing same
EP0118564B1 (en)	1987-04-22	4-amino-tetrahydro-2-naphthoic acid derivatives
GB2171997A (en)	1986-09-10	4-Amino-6,7-dimethoxy-2-Piperazin-1-ylquinazoline derivatives
JPS63295561A (ja)	1988-12-01	２−キノロン誘導体
US3898224A (en)	1975-08-05	1,6,7,8-Tetrahydro-4-oxo-4H-pyrido {8 1,2-A{9 pyrimidine-9-carboalkoxy compounds
US4721715A (en)	1988-01-26	Derivatives of 4-(arylpiperazinyl-ethylaminoethoxy) phenol useful for effecting hypolipidemic therapy or cardiovascular therapy
US3917833A (en)	1975-11-04	Amino-substituted benzocycloheptenones for inducing sleep
JPS6130588A (ja)	1986-02-12	ベンゾ〔ｃ〕〔１，８〕ナフチリジン、その製造方法及びその使用、並びにこれらの化合物を含有する調製剤
US4452982A (en)	1984-06-05	Process for the preparation of nitrogen-bridgehead condensed pyrimidine compounds, and pharmaceutical compositions containing them
US4199582A (en)	1980-04-22	Piperazine containing dihydronaphthalene derivatives and compositions
PL121605B1 (en)	1982-05-31	Proces for preparing 5-substituted 10,11-dihydro-5h-dibenzo-/a,d/cyclohepteno-5,10-imineszo ciklogepten-5,10-iminov
JPS5825678B2 (ja)	1983-05-28	オキサゾ−ルユウドウタイノセイゾウホウ