CR20230566A - Derivados de triazina y su uso en el tratamiento del cáncer - Google Patents
Derivados de triazina y su uso en el tratamiento del cáncerInfo
- Publication number
- CR20230566A CR20230566A CR20230566A CR20230566A CR20230566A CR 20230566 A CR20230566 A CR 20230566A CR 20230566 A CR20230566 A CR 20230566A CR 20230566 A CR20230566 A CR 20230566A CR 20230566 A CR20230566 A CR 20230566A
- Authority
- CR
- Costa Rica
- Prior art keywords
- sup
- cancer
- treatment
- triazine derivatives
- compounds
- Prior art date
Links
- 206010028980 Neoplasm Diseases 0.000 title 1
- 201000011510 cancer Diseases 0.000 title 1
- 150000003918 triazines Chemical class 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
- C07D253/02—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 not condensed with other rings
- C07D253/06—1,2,4-Triazines
- C07D253/065—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members
- C07D253/07—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members with hetero atoms, or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Abstract
La invención se refiere a compuestos novedosos que tienen la fórmula general Ib, en donde R1, R2, R3, R4, R5 y Z son como se describen en la presente, una composición que incluye los compuestos y métodos para usar los compuestos.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP21177660 | 2021-06-04 | ||
EP21188639 | 2021-07-30 | ||
EP21215875 | 2021-12-20 | ||
PCT/EP2022/064995 WO2022253936A1 (en) | 2021-06-04 | 2022-06-02 | Triazine derivatives and their use in the treatment of cancer. |
Publications (1)
Publication Number | Publication Date |
---|---|
CR20230566A true CR20230566A (es) | 2024-01-22 |
Family
ID=82115763
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CR20230566A CR20230566A (es) | 2021-06-04 | 2022-06-02 | Derivados de triazina y su uso en el tratamiento del cáncer |
Country Status (11)
Country | Link |
---|---|
EP (1) | EP4347571A1 (es) |
KR (1) | KR20240019083A (es) |
AR (1) | AR126053A1 (es) |
AU (1) | AU2022287224A1 (es) |
BR (1) | BR112023025318A2 (es) |
CA (1) | CA3216026A1 (es) |
CO (1) | CO2023016212A2 (es) |
CR (1) | CR20230566A (es) |
IL (1) | IL307201A (es) |
TW (1) | TW202313577A (es) |
WO (1) | WO2022253936A1 (es) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TW202327604A (zh) * | 2022-01-07 | 2023-07-16 | 大陸商藥捷安康(南京)科技股份有限公司 | Nlrp3發炎小體抑制劑及其應用 |
US11618751B1 (en) | 2022-03-25 | 2023-04-04 | Ventus Therapeutics U.S., Inc. | Pyrido-[3,4-d]pyridazine amine derivatives useful as NLRP3 derivatives |
WO2024017924A1 (en) * | 2022-07-21 | 2024-01-25 | F. Hoffmann-La Roche Ag | Nlrp3 inhibitors |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP3920917A4 (en) * | 2019-02-04 | 2022-09-28 | Skyhawk Therapeutics, Inc. | METHODS AND COMPOSITIONS FOR MODULATION OF SPLICING |
AR119731A1 (es) | 2019-05-17 | 2022-01-05 | Novartis Ag | Inhibidores del inflamasoma nlrp3 |
WO2021150574A1 (en) | 2020-01-22 | 2021-07-29 | Genentech, Inc. | Sulfonimidamide compounds as nlrp3 modulators |
-
2022
- 2022-06-02 AU AU2022287224A patent/AU2022287224A1/en active Pending
- 2022-06-02 CA CA3216026A patent/CA3216026A1/en active Pending
- 2022-06-02 AR ARP220101456A patent/AR126053A1/es unknown
- 2022-06-02 BR BR112023025318A patent/BR112023025318A2/pt unknown
- 2022-06-02 WO PCT/EP2022/064995 patent/WO2022253936A1/en active Application Filing
- 2022-06-02 TW TW111120574A patent/TW202313577A/zh unknown
- 2022-06-02 CR CR20230566A patent/CR20230566A/es unknown
- 2022-06-02 IL IL307201A patent/IL307201A/en unknown
- 2022-06-02 EP EP22731614.8A patent/EP4347571A1/en active Pending
- 2022-06-02 KR KR1020237039328A patent/KR20240019083A/ko unknown
-
2023
- 2023-11-29 CO CONC2023/0016212A patent/CO2023016212A2/es unknown
Also Published As
Publication number | Publication date |
---|---|
KR20240019083A (ko) | 2024-02-14 |
EP4347571A1 (en) | 2024-04-10 |
BR112023025318A2 (pt) | 2024-02-27 |
AR126053A1 (es) | 2023-09-06 |
TW202313577A (zh) | 2023-04-01 |
AU2022287224A1 (en) | 2023-09-21 |
CA3216026A1 (en) | 2022-12-08 |
IL307201A (en) | 2023-11-01 |
WO2022253936A1 (en) | 2022-12-08 |
CO2023016212A2 (es) | 2023-12-11 |
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