CR10573A - Derivados del pirazol como inhibidores del citocromo p450 - Google Patents
Derivados del pirazol como inhibidores del citocromo p450Info
- Publication number
- CR10573A CR10573A CR10573A CR10573A CR10573A CR 10573 A CR10573 A CR 10573A CR 10573 A CR10573 A CR 10573A CR 10573 A CR10573 A CR 10573A CR 10573 A CR10573 A CR 10573A
- Authority
- CR
- Costa Rica
- Prior art keywords
- citocromo
- pirazol
- inhibitors
- derivatives
- methods
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
Abstract
La presente invencion proporciona compuestos de formula (I), o sales o solvatos de los mismos farmaceuticamente aceptables, procedimientos para prepararlos, procedimientos para usarlos y formulaciones farmaceuticas que los comprenden.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US80659606P | 2006-07-05 | 2006-07-05 | |
US91098807P | 2007-04-10 | 2007-04-10 | |
US94180807P | 2007-06-04 | 2007-06-04 |
Publications (1)
Publication Number | Publication Date |
---|---|
CR10573A true CR10573A (es) | 2009-02-12 |
Family
ID=38515807
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CR10573A CR10573A (es) | 2006-07-05 | 2009-01-20 | Derivados del pirazol como inhibidores del citocromo p450 |
Country Status (24)
Country | Link |
---|---|
US (1) | US7919488B2 (es) |
EP (1) | EP2046774A1 (es) |
KR (1) | KR20090034958A (es) |
CN (1) | CN101511812A (es) |
AP (1) | AP2009004763A0 (es) |
AR (1) | AR062154A1 (es) |
AU (1) | AU2007270814B2 (es) |
CA (1) | CA2660031A1 (es) |
CO (1) | CO6150178A2 (es) |
CR (1) | CR10573A (es) |
EA (1) | EA200900135A1 (es) |
GT (1) | GT200700053A (es) |
IL (1) | IL196490A0 (es) |
MA (1) | MA30629B1 (es) |
MX (1) | MX2009000482A (es) |
NO (1) | NO20090346L (es) |
NZ (1) | NZ574207A (es) |
PE (1) | PE20080998A1 (es) |
RS (1) | RS20090036A (es) |
TN (1) | TN2009000033A1 (es) |
TW (1) | TWI334867B (es) |
UY (1) | UY30460A1 (es) |
WO (1) | WO2008004096A1 (es) |
ZA (1) | ZA200900478B (es) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2099454A4 (en) * | 2006-11-17 | 2010-11-10 | Abbott Lab | AMINOPYRROLIDINES AS CHEMOKINE RECEPTOR ANTAGONISTS |
BRPI0721451A2 (pt) * | 2007-03-13 | 2014-03-25 | Arete Therapeutics Inc | Compostos de 4-piperidiniluréia como inibidores de epóxido hidrolase solúvel |
US8242145B2 (en) | 2008-02-14 | 2012-08-14 | Panmira Pharmaceuticals, Llc | Cyclic diaryl ether compounds as antagonists of prostaglandin D2 receptors |
EP2268611A2 (en) | 2008-04-02 | 2011-01-05 | Amira Pharmaceuticals, Inc. | Aminoalkylphenyl antagonists of prostaglandin d2 receptors |
DE102009041242A1 (de) | 2009-09-11 | 2011-12-15 | Bayer Schering Pharma Aktiengesellschaft | Heterocyclisch substituierte Aryl-Verbindungen und ihre Verwendung |
DE102008057344A1 (de) | 2008-11-14 | 2010-05-20 | Bayer Schering Pharma Aktiengesellschaft | Aminoalkyl-substituierte Aryl-Verbindungen und ihre Verwendung |
DE102008057343A1 (de) | 2008-11-14 | 2010-05-20 | Bayer Schering Pharma Aktiengesellschaft | Heterocyclisch substituierte Aryl-Verbindungen und ihre Verwendung |
DE102008057364A1 (de) | 2008-11-14 | 2010-05-20 | Bayer Schering Pharma Aktiengesellschaft | Substituierte Aryl-Verbindungen und ihre Verwendung |
DE102009041241A1 (de) | 2009-09-11 | 2011-08-04 | Bayer Schering Pharma Aktiengesellschaft, 13353 | Substituierte Aryl-Verbindungen und ihre Verwendung |
WO2010057118A2 (en) | 2008-11-17 | 2010-05-20 | Amira Pharmaceuticals, Inc. | Heterocyclic antagonists of prostaglandin d2 receptors |
CN107021951B (zh) | 2010-06-30 | 2020-10-20 | 赛克里翁治疗有限公司 | sGC刺激物 |
AU2011326241B2 (en) | 2010-11-09 | 2016-11-17 | Ironwood Pharmaceuticals, Inc. | sGC stimulators |
EP2797915B1 (en) | 2011-12-27 | 2016-07-13 | Ironwood Pharmaceuticals, Inc. | 2-benzyl-3-(oxazole/thiazole)-5-(pyrimidin-2-yl)-1(H)-pyrazole derivatives as stimulators of the soluble guanylate cyclase (sGC) for the treatment of e.g. hypertension or heart failure |
CN104540813A (zh) * | 2012-06-27 | 2015-04-22 | 默沙东公司 | 磺酰胺衍生物以及使用它们用于改善药物的药物动力学的方法 |
WO2014000178A1 (en) * | 2012-06-27 | 2014-01-03 | Merck Sharp & Dohme Corp. | Sulfonamide derivatives and methods of use thereof for improving the pharmacokinetics of a drug |
WO2014194519A1 (en) | 2013-06-07 | 2014-12-11 | Merck Sharp & Dohme Corp. | Imidazole derivatives and methods of use thereof for improving pharmacokinetics of drug |
WO2015070367A1 (en) | 2013-11-12 | 2015-05-21 | Merck Sharp & Dohme Corp. | Piperidine or piperazine linked imidazole and triazole derivatives and methods of use thereof for improving the pharmacokinetics of a drug |
WO2015070366A1 (en) | 2013-11-12 | 2015-05-21 | Merck Sharp & Dohme Corp. | Aryl linked imidazole and triazole derivatives and methods of use thereof for improving the pharmacokinetics of a drug |
WO2020163689A1 (en) * | 2019-02-08 | 2020-08-13 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | 20-hete formation inhibitors |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0024795D0 (en) * | 2000-10-10 | 2000-11-22 | Hoffmann La Roche | Pyrazole derivatives for the treatment of viral diseases |
HUP0400823A3 (en) * | 2001-04-05 | 2010-06-28 | Torrent Pharmaceuticals Ltd | Heterocyclic compounds for treating aging-related and diabetic vascular complications, their preparation and pharmaceutical compositions containing them |
US7008953B2 (en) * | 2003-07-30 | 2006-03-07 | Agouron Pharmaceuticals, Inc. | 3, 5 Disubstituted indazole compounds, pharmaceutical compositions, and methods for mediating or inhibiting cell proliferation |
US7662844B2 (en) * | 2004-07-12 | 2010-02-16 | Osi Pharmaceuticals, Inc. | Naphthylene derivatives as cytochrome P450 inhibitors |
KR100975448B1 (ko) * | 2005-09-23 | 2010-08-11 | 화이자 프로덕츠 인크. | 시토크롬 p450 3a4 (cyp3a4) 억제제로서의피리딘아미노술포닐 치환된 벤즈아미드 |
-
2007
- 2007-06-25 EA EA200900135A patent/EA200900135A1/ru unknown
- 2007-06-25 AU AU2007270814A patent/AU2007270814B2/en not_active Ceased
- 2007-06-25 CN CNA200780032889XA patent/CN101511812A/zh active Pending
- 2007-06-25 NZ NZ574207A patent/NZ574207A/en not_active IP Right Cessation
- 2007-06-25 WO PCT/IB2007/001878 patent/WO2008004096A1/en active Application Filing
- 2007-06-25 MX MX2009000482A patent/MX2009000482A/es not_active Application Discontinuation
- 2007-06-25 RS RSP-2009/0036A patent/RS20090036A/sr unknown
- 2007-06-25 KR KR1020097002315A patent/KR20090034958A/ko not_active Application Discontinuation
- 2007-06-25 EP EP07734950A patent/EP2046774A1/en not_active Withdrawn
- 2007-06-25 CA CA002660031A patent/CA2660031A1/en not_active Abandoned
- 2007-06-25 AP AP2009004763A patent/AP2009004763A0/xx unknown
- 2007-06-28 US US11/770,698 patent/US7919488B2/en not_active Expired - Fee Related
- 2007-07-03 AR ARP070102977A patent/AR062154A1/es not_active Application Discontinuation
- 2007-07-04 PE PE2007000860A patent/PE20080998A1/es not_active Application Discontinuation
- 2007-07-04 GT GT200700053A patent/GT200700053A/es unknown
- 2007-07-04 TW TW096124262A patent/TWI334867B/zh not_active IP Right Cessation
- 2007-07-04 UY UY30460A patent/UY30460A1/es unknown
-
2009
- 2009-01-13 IL IL196490A patent/IL196490A0/en unknown
- 2009-01-20 CR CR10573A patent/CR10573A/es unknown
- 2009-01-21 ZA ZA200900478A patent/ZA200900478B/xx unknown
- 2009-01-22 NO NO20090346A patent/NO20090346L/no not_active Application Discontinuation
- 2009-01-30 TN TN2009000033A patent/TN2009000033A1/fr unknown
- 2009-02-04 CO CO09010549A patent/CO6150178A2/es unknown
- 2009-02-05 MA MA31618A patent/MA30629B1/fr unknown
Also Published As
Publication number | Publication date |
---|---|
AR062154A1 (es) | 2008-10-22 |
TW200811159A (en) | 2008-03-01 |
KR20090034958A (ko) | 2009-04-08 |
TWI334867B (en) | 2010-12-21 |
EP2046774A1 (en) | 2009-04-15 |
GT200700053A (es) | 2009-08-03 |
NO20090346L (no) | 2009-02-19 |
TN2009000033A1 (fr) | 2010-08-19 |
AU2007270814A1 (en) | 2008-01-10 |
AU2007270814B2 (en) | 2011-07-14 |
IL196490A0 (en) | 2011-07-31 |
AP2009004763A0 (en) | 2009-02-28 |
NZ574207A (en) | 2010-10-29 |
MA30629B1 (fr) | 2009-08-03 |
MX2009000482A (es) | 2009-01-27 |
RS20090036A (en) | 2010-06-30 |
PE20080998A1 (es) | 2008-08-15 |
UY30460A1 (es) | 2008-02-29 |
US20080021011A1 (en) | 2008-01-24 |
ZA200900478B (en) | 2010-04-28 |
EA200900135A1 (ru) | 2009-06-30 |
CN101511812A (zh) | 2009-08-19 |
CO6150178A2 (es) | 2010-04-20 |
US7919488B2 (en) | 2011-04-05 |
CA2660031A1 (en) | 2008-01-10 |
WO2008004096A1 (en) | 2008-01-10 |
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