CO7310521A2 - Composición farmaceútica que tiene fluidez mejorada, agente medicional, y método para la producción y uso del mismo - Google Patents
Composición farmaceútica que tiene fluidez mejorada, agente medicional, y método para la producción y uso del mismoInfo
- Publication number
- CO7310521A2 CO7310521A2 CO15003855A CO15003855A CO7310521A2 CO 7310521 A2 CO7310521 A2 CO 7310521A2 CO 15003855 A CO15003855 A CO 15003855A CO 15003855 A CO15003855 A CO 15003855A CO 7310521 A2 CO7310521 A2 CO 7310521A2
- Authority
- CO
- Colombia
- Prior art keywords
- pharmaceutical composition
- improved fluidity
- production
- octylphenyl
- propane
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4866—Organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
- A61J3/07—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use
- A61J3/071—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use into the form of telescopically engaged two-piece capsules
- A61J3/074—Filling capsules; Related operations
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Virology (AREA)
- Inorganic Chemistry (AREA)
- Transplantation (AREA)
- Communicable Diseases (AREA)
- Molecular Biology (AREA)
- Oncology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Psychiatry (AREA)
- AIDS & HIV (AREA)
- Pain & Pain Management (AREA)
- Tropical Medicine & Parasitology (AREA)
- Hospice & Palliative Care (AREA)
- Emergency Medicine (AREA)
- Rheumatology (AREA)
- Biophysics (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Abstract
La invención se encuentra relacionada al campo de loscompuestos farmacéuticos, en particular, a una composiciónfarmacéutica sólida que comprende 2-amino-2-[2-(4-octilfenil)etil]propano-1,3-diol o sal farmacéuticamenteaceptable del mismo, estabilizador, lubricante y rellenador;un método para la preparación de una composiciónfarmacéutica, a medicamentos para supresión inmune ytratamiento de la esclerosis múltiple. El 2-Amino-2-[2-(4-octilfenil)etil]propano-1,3-diol representa un moduladorinmune, el cual produce la redistribución de linfocitos delfluido sanguíneo a tejidos linfoides secundarios queconllevan a la supresión inmune. La invención proporciona unadistribución uniforme del ingrediente activo en lacomposición sólida, alta estabilidad y fluidez mejorada de lacomposición farmacéutica sólida. Debida a la fluidez mejoradaLas composiciones sugeridas en la invención pueden ser usadosen equipos automáticos.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
RU2012129101/15A RU2496486C1 (ru) | 2012-07-11 | 2012-07-11 | Фармацевтическая композиция с улучшенной сыпучестью, лекарственное средство, способ получения и применение |
Publications (1)
Publication Number | Publication Date |
---|---|
CO7310521A2 true CO7310521A2 (es) | 2015-06-30 |
Family
ID=49446598
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CO15003855A CO7310521A2 (es) | 2012-07-11 | 2015-01-08 | Composición farmaceútica que tiene fluidez mejorada, agente medicional, y método para la producción y uso del mismo |
Country Status (22)
Country | Link |
---|---|
US (1) | US9370576B2 (es) |
EP (1) | EP2873416B1 (es) |
JP (1) | JP6093015B2 (es) |
KR (1) | KR20150036228A (es) |
CN (1) | CN104487063B (es) |
AP (1) | AP2014008171A0 (es) |
BR (1) | BR112015000544A2 (es) |
CL (1) | CL2015000052A1 (es) |
CO (1) | CO7310521A2 (es) |
EA (1) | EA027712B1 (es) |
GE (1) | GEP201606571B (es) |
IL (1) | IL236562A0 (es) |
IN (1) | IN2015DN00130A (es) |
MA (1) | MA37693B1 (es) |
MX (1) | MX2015000467A (es) |
PE (1) | PE20150632A1 (es) |
RU (1) | RU2496486C1 (es) |
SG (1) | SG11201500178QA (es) |
TN (1) | TN2015000006A1 (es) |
UA (1) | UA113216C2 (es) |
WO (1) | WO2014011083A2 (es) |
ZA (1) | ZA201409481B (es) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2014110398A1 (en) | 2013-01-10 | 2014-07-17 | Edh Us Llc | Ball spin rate measurement |
RU2611415C1 (ru) * | 2015-11-17 | 2017-02-21 | Общество С Ограниченной Ответственностью "Валента - Интеллект" | ФАРМАЦЕВТИЧЕСКАЯ КОМПОЗИЦИЯ, ОБЛАДАЮЩАЯ ТЕРАПЕВТИЧЕСКИМ ЭФФЕКТОМ В ОТНОШЕНИИ ДЕМИЕЛИНИЗИРУЮЩИХ ЗАБОЛЕВАНИЙ (Варианты) |
WO2020005189A2 (en) * | 2018-06-27 | 2020-01-02 | Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi | Solid oral pharmaceutical compositions comprising teriflunomide |
Family Cites Families (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR0155015B1 (ko) | 1992-10-21 | 1998-12-01 | 고우야 마사시 | 2-아미노-1,3-프로판디올 화합물 및 면역 억제제 |
SK282225B6 (sk) | 1995-12-28 | 2001-12-03 | Welfide Corporation | Použitie 2-amino-2[2-(4-oktylfenyl)etyl]-propán-1,3-diolu alebo jeho farmaceuticky prijateľnej adičnej soli s kyselinou na výrobu farmaceutického prostriedku |
US6476004B1 (en) | 1996-07-18 | 2002-11-05 | Mitsubishi Pharma Corporation | Pharmaceutical composition |
GB9624038D0 (en) | 1996-11-19 | 1997-01-08 | Sandoz Ltd | Organic compounds |
JPH1180026A (ja) | 1997-09-02 | 1999-03-23 | Yoshitomi Pharmaceut Ind Ltd | 新規免疫抑制剤、その使用方法およびその同定方法 |
JP4627356B2 (ja) * | 1999-06-30 | 2011-02-09 | 松森 昭 | ウイルス性心筋炎の予防または治療薬剤 |
JP2002316985A (ja) | 2001-04-20 | 2002-10-31 | Sankyo Co Ltd | ベンゾチオフェン誘導体 |
RU2358717C2 (ru) | 2002-05-16 | 2009-06-20 | Новартис Аг | Применение средств, связывающих edg-рецептор, в лечении ракового заболевания |
DE122011100047I1 (de) * | 2003-04-08 | 2011-12-15 | Mitsubishi Tanabe Pharma Corp | Feste pharmazeutische darreichungsformen mit einemS1P rezeptoragonisten und einem zuckeralkohol. |
EP1663188B1 (en) * | 2003-09-12 | 2016-08-10 | Newron Sweden AB | Treatment of disorders of the nervous system |
RU2402324C2 (ru) | 2004-07-30 | 2010-10-27 | Новартис Аг | Композиции на основе соединений 2-амино-1,3-пропандиола |
GT200600350A (es) | 2005-08-09 | 2007-03-28 | Formulaciones líquidas | |
MXPA05008573A (es) | 2005-08-12 | 2007-02-12 | Leopoldo Espinosa Abdala | Composicion de isoflavonas para tratamiento de los sintomas y trastornos fisiologicos de la menopausia. |
EP1923058A1 (en) * | 2006-09-26 | 2008-05-21 | Novartis AG | Coated pharmaceutical composition comprising an S1P agonist or modulator |
EP3103448B1 (en) * | 2006-09-26 | 2019-07-03 | Novartis Ag | Pharmaceutical compositions comprising an s1p modulator |
WO2009048993A2 (en) * | 2007-10-12 | 2009-04-16 | Novartis Ag | Compositions comprising sphingosine 1 phosphate (s1p) receptor modulators |
EP2560621A1 (en) * | 2010-04-22 | 2013-02-27 | Ratiopharm GmbH | Fingolimod in the form of a solid solution |
CA2797551A1 (en) * | 2010-04-22 | 2011-10-27 | Ratiopharm Gmbh | Melt-granulated fingolimod |
-
2012
- 2012-07-11 RU RU2012129101/15A patent/RU2496486C1/ru active
-
2013
- 2013-05-07 UA UAA201500892A patent/UA113216C2/uk unknown
- 2013-07-05 CN CN201380036592.6A patent/CN104487063B/zh not_active Expired - Fee Related
- 2013-07-05 EA EA201500096A patent/EA027712B1/ru not_active IP Right Cessation
- 2013-07-05 PE PE2015000009A patent/PE20150632A1/es not_active Application Discontinuation
- 2013-07-05 GE GEAP201313729A patent/GEP201606571B/en unknown
- 2013-07-05 JP JP2015521577A patent/JP6093015B2/ja not_active Expired - Fee Related
- 2013-07-05 US US14/410,584 patent/US9370576B2/en not_active Expired - Fee Related
- 2013-07-05 BR BR112015000544A patent/BR112015000544A2/pt active Search and Examination
- 2013-07-05 SG SG11201500178QA patent/SG11201500178QA/en unknown
- 2013-07-05 WO PCT/RU2013/000572 patent/WO2014011083A2/ru active Application Filing
- 2013-07-05 MX MX2015000467A patent/MX2015000467A/es unknown
- 2013-07-05 EP EP13817392.7A patent/EP2873416B1/en not_active Not-in-force
- 2013-07-05 AP AP2014008171A patent/AP2014008171A0/xx unknown
- 2013-07-05 KR KR1020157002215A patent/KR20150036228A/ko not_active Application Discontinuation
-
2014
- 2014-12-22 ZA ZA2014/09481A patent/ZA201409481B/en unknown
- 2014-12-24 MA MA37693A patent/MA37693B1/fr unknown
-
2015
- 2015-01-01 IL IL236562A patent/IL236562A0/en unknown
- 2015-01-06 IN IN130DEN2015 patent/IN2015DN00130A/en unknown
- 2015-01-07 TN TNP2015000006A patent/TN2015000006A1/fr unknown
- 2015-01-08 CL CL2015000052A patent/CL2015000052A1/es unknown
- 2015-01-08 CO CO15003855A patent/CO7310521A2/es unknown
Also Published As
Publication number | Publication date |
---|---|
TN2015000006A1 (en) | 2016-06-29 |
CN104487063A (zh) | 2015-04-01 |
IL236562A0 (en) | 2015-02-26 |
IN2015DN00130A (es) | 2015-05-29 |
JP6093015B2 (ja) | 2017-03-08 |
GEP201606571B (en) | 2016-11-10 |
MX2015000467A (es) | 2015-06-05 |
WO2014011083A2 (ru) | 2014-01-16 |
PE20150632A1 (es) | 2015-05-20 |
UA113216C2 (xx) | 2016-12-26 |
SG11201500178QA (en) | 2015-03-30 |
EP2873416B1 (en) | 2017-04-26 |
EP2873416A4 (en) | 2016-03-16 |
CN104487063B (zh) | 2017-05-10 |
BR112015000544A2 (pt) | 2017-10-24 |
US20150335754A1 (en) | 2015-11-26 |
WO2014011083A3 (ru) | 2014-03-06 |
ZA201409481B (en) | 2016-02-24 |
EP2873416A2 (en) | 2015-05-20 |
CL2015000052A1 (es) | 2015-09-04 |
EA027712B1 (ru) | 2017-08-31 |
KR20150036228A (ko) | 2015-04-07 |
US9370576B2 (en) | 2016-06-21 |
AP2014008171A0 (en) | 2014-12-31 |
EA201500096A1 (ru) | 2015-05-29 |
JP2015522068A (ja) | 2015-08-03 |
RU2496486C1 (ru) | 2013-10-27 |
MA37693B1 (fr) | 2017-01-31 |
MA37693A1 (fr) | 2016-06-30 |
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