CO7091179A2 - Nuevos derivados de tienopirimidina, procesos para su preparacion y sus usos terapeuticos - Google Patents
Nuevos derivados de tienopirimidina, procesos para su preparacion y sus usos terapeuticosInfo
- Publication number
- CO7091179A2 CO7091179A2 CO14219119A CO14219119A CO7091179A2 CO 7091179 A2 CO7091179 A2 CO 7091179A2 CO 14219119 A CO14219119 A CO 14219119A CO 14219119 A CO14219119 A CO 14219119A CO 7091179 A2 CO7091179 A2 CO 7091179A2
- Authority
- CO
- Colombia
- Prior art keywords
- thienopyrimidine
- processes
- preparation
- therapeutic uses
- new derivatives
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/553—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one oxygen as ring hetero atoms, e.g. loxapine, staurosporine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
Abstract
VER ANEXOS
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR1253044A FR2988722B1 (fr) | 2012-04-03 | 2012-04-03 | Nouveaux derives de thienopyrimidines, leurs procedes de preparation et leurs utilisations therapeutiques |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CO7091179A2 true CO7091179A2 (es) | 2014-10-21 |
Family
ID=48095815
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CO14219119A CO7091179A2 (es) | 2012-04-03 | 2014-10-03 | Nuevos derivados de tienopirimidina, procesos para su preparacion y sus usos terapeuticos |
Country Status (38)
| Country | Link |
|---|---|
| US (6) | US9115140B2 (es) |
| EP (1) | EP2834248B1 (es) |
| JP (1) | JP6096278B2 (es) |
| KR (1) | KR102039764B1 (es) |
| CN (2) | CN107652303B (es) |
| AR (1) | AR090572A1 (es) |
| AU (1) | AU2013244992B2 (es) |
| BR (1) | BR112014024489B1 (es) |
| CA (1) | CA2868685C (es) |
| CL (1) | CL2014002661A1 (es) |
| CO (1) | CO7091179A2 (es) |
| CR (1) | CR20140435A (es) |
| CY (1) | CY1117843T1 (es) |
| DK (1) | DK2834248T3 (es) |
| DO (1) | DOP2014000216A (es) |
| EA (1) | EA025558B1 (es) |
| ES (1) | ES2577382T3 (es) |
| FR (1) | FR2988722B1 (es) |
| HK (2) | HK1201263A1 (es) |
| HR (1) | HRP20160649T1 (es) |
| HU (1) | HUE027895T2 (es) |
| IL (1) | IL234960A (es) |
| MA (1) | MA37384B1 (es) |
| MX (1) | MX355104B (es) |
| MY (1) | MY166151A (es) |
| PE (1) | PE20150289A1 (es) |
| PH (1) | PH12014502180A1 (es) |
| PL (1) | PL2834248T3 (es) |
| PT (1) | PT2834248E (es) |
| RS (1) | RS54850B1 (es) |
| SG (1) | SG11201406091RA (es) |
| SI (1) | SI2834248T1 (es) |
| TN (1) | TN2014000415A1 (es) |
| TW (1) | TWI579288B (es) |
| UA (1) | UA112685C2 (es) |
| UY (1) | UY34725A (es) |
| WO (1) | WO2013150036A1 (es) |
| ZA (1) | ZA201407021B (es) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2988722B1 (fr) | 2012-04-03 | 2014-05-09 | Sanofi Sa | Nouveaux derives de thienopyrimidines, leurs procedes de preparation et leurs utilisations therapeutiques |
| CN110372720B (zh) * | 2014-05-28 | 2021-03-05 | 锦州奥鸿药业有限责任公司 | 一类激酶抑制剂 |
| CN111440189B (zh) * | 2015-04-24 | 2022-08-09 | 广州再极医药科技有限公司 | 稠环嘧啶氨基衍生物、其制备方法、中间体、药物组合物及应用 |
| CN113549069A (zh) * | 2015-12-27 | 2021-10-26 | 重庆复创医药研究有限公司 | 一类激酶抑制剂 |
| MX2018013573A (es) * | 2016-05-07 | 2019-08-01 | Shanghai Fochon Pharmaceutical Co Ltd | Ciertos inhibidores de la proteína cinasa. |
| UA126589C2 (uk) | 2017-09-14 | 2022-11-02 | Даїті Санкіо Компані, Лімітед | Сполука, яка має циклічну структуру |
| ES2910071T3 (es) | 2018-03-08 | 2022-05-11 | Incyte Corp | Compuestos de aminopirazina diol como inhibidores de PI3K-Y |
| CN110551142B (zh) * | 2018-05-31 | 2023-05-12 | 上海再极医药科技有限公司 | 一种稠环嘧啶类化合物的盐、晶型及其制备方法和应用 |
| WO2020010003A1 (en) | 2018-07-02 | 2020-01-09 | Incyte Corporation | AMINOPYRAZINE DERIVATIVES AS PI3K-γ INHIBITORS |
| US11034669B2 (en) | 2018-11-30 | 2021-06-15 | Nuvation Bio Inc. | Pyrrole and pyrazole compounds and methods of use thereof |
| CN110922421B (zh) * | 2019-12-17 | 2023-05-05 | 安徽英特美科技有限公司 | 一种n-甲基-1,2,5,6-四氢吡啶-4-硼酸频哪醇酯的合成方法 |
| WO2021180032A1 (en) * | 2020-03-13 | 2021-09-16 | Guangzhou Maxinovel Pharmaceuticals Co., Ltd. | Novel Therapeutic Methods |
| CN116731035A (zh) * | 2022-03-08 | 2023-09-12 | 广州再极医药科技有限公司 | 一种噻吩并嘧啶类化合物、中间体、其制备方法、组合物和应用 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1470356A1 (de) * | 1964-01-15 | 1970-04-30 | Thomae Gmbh Dr K | Neue Thieno[3,2-d]pyrimidine und Verfahren zu ihrer Herstellung |
| CN1280580A (zh) * | 1997-11-11 | 2001-01-17 | 辉瑞产品公司 | 用作抗癌药的噻吩并嘧啶和噻吩并吡啶衍生物 |
| EP1181296A1 (en) | 1999-06-03 | 2002-02-27 | Abbott Laboratories | Cell adhesion-inhibiting antiinflammatory compounds |
| DE10042997A1 (de) | 2000-09-01 | 2002-03-14 | Merck Patent Gmbh | Thienopyrimidine |
| US20080108611A1 (en) | 2006-01-19 | 2008-05-08 | Battista Kathleen A | Substituted thienopyrimidine kinase inhibitors |
| KR101402474B1 (ko) * | 2006-04-26 | 2014-06-19 | 제넨테크, 인크. | 포스포이노시티드 3-키나제 억제제 화합물 및 이를 포함하는 약학적 조성물 |
| AU2007333394C1 (en) | 2006-12-08 | 2011-08-18 | Novartis Ag | Compounds and compositions as protein kinase inhibitors |
| EP3109249A1 (en) * | 2007-11-15 | 2016-12-28 | YM BioSciences Australia Pty Ltd | N-containing heterocyclic compounds |
| DE102008017853A1 (de) * | 2008-04-09 | 2009-10-15 | Merck Patent Gmbh | Thienopyrimidine |
| KR101147550B1 (ko) * | 2009-10-22 | 2012-05-17 | 한국과학기술연구원 | 단백질 키나아제 저해활성을 가지는 2,7-치환된 티에노［3,2-ｄ］피리미딘 화합물 |
| KR101094446B1 (ko) * | 2009-11-19 | 2011-12-15 | 한국과학기술연구원 | 단백질 키나아제 저해활성을 가지는 2,4,7-치환된 티에노［3,2-ｄ］피리미딘 화합물 |
| WO2012004900A1 (en) | 2010-07-09 | 2012-01-12 | Aska Pharmaceutical Co., Ltd. | Thienopyrimidine compounds |
| FR2988722B1 (fr) | 2012-04-03 | 2014-05-09 | Sanofi Sa | Nouveaux derives de thienopyrimidines, leurs procedes de preparation et leurs utilisations therapeutiques |
-
2012
- 2012-04-03 FR FR1253044A patent/FR2988722B1/fr active Active
-
2013
- 2013-02-04 UA UAA201411826A patent/UA112685C2/uk unknown
- 2013-04-02 CN CN201710950612.0A patent/CN107652303B/zh active Active
- 2013-04-02 HU HUE13716241A patent/HUE027895T2/en unknown
- 2013-04-02 SI SI201330203A patent/SI2834248T1/sl unknown
- 2013-04-02 CN CN201380029174.4A patent/CN104540834B/zh active Active
- 2013-04-02 KR KR1020147030322A patent/KR102039764B1/ko active IP Right Grant
- 2013-04-02 EP EP13716241.8A patent/EP2834248B1/en active Active
- 2013-04-02 PL PL13716241.8T patent/PL2834248T3/pl unknown
- 2013-04-02 DK DK13716241.8T patent/DK2834248T3/en active
- 2013-04-02 US US13/855,246 patent/US9115140B2/en active Active
- 2013-04-02 CA CA2868685A patent/CA2868685C/en active Active
- 2013-04-02 MY MYPI2014002724A patent/MY166151A/en unknown
- 2013-04-02 RS RS20160436A patent/RS54850B1/sr unknown
- 2013-04-02 WO PCT/EP2013/056958 patent/WO2013150036A1/en active Application Filing
- 2013-04-02 PE PE2014001523A patent/PE20150289A1/es active IP Right Grant
- 2013-04-02 MA MA37384A patent/MA37384B1/fr unknown
- 2013-04-02 JP JP2015503860A patent/JP6096278B2/ja active Active
- 2013-04-02 SG SG11201406091RA patent/SG11201406091RA/en unknown
- 2013-04-02 MX MX2014011921A patent/MX355104B/es active IP Right Grant
- 2013-04-02 EA EA201491820A patent/EA025558B1/ru not_active IP Right Cessation
- 2013-04-02 ES ES13716241.8T patent/ES2577382T3/es active Active
- 2013-04-02 AU AU2013244992A patent/AU2013244992B2/en active Active
- 2013-04-02 BR BR112014024489-8A patent/BR112014024489B1/pt not_active IP Right Cessation
- 2013-04-02 PT PT137162418T patent/PT2834248E/pt unknown
- 2013-04-03 AR ARP130101067A patent/AR090572A1/es active IP Right Grant
- 2013-04-03 TW TW102112260A patent/TWI579288B/zh active
- 2013-04-03 UY UY0001034725A patent/UY34725A/es not_active Application Discontinuation
-
2014
- 2014-09-22 CR CR20140435A patent/CR20140435A/es unknown
- 2014-09-25 DO DO2014000216A patent/DOP2014000216A/es unknown
- 2014-09-26 ZA ZA2014/07021A patent/ZA201407021B/en unknown
- 2014-09-29 PH PH12014502180A patent/PH12014502180A1/en unknown
- 2014-09-30 TN TNP2014000415A patent/TN2014000415A1/fr unknown
- 2014-10-02 IL IL234960A patent/IL234960A/en active IP Right Grant
- 2014-10-02 CL CL2014002661A patent/CL2014002661A1/es unknown
- 2014-10-03 CO CO14219119A patent/CO7091179A2/es unknown
-
2015
- 2015-02-17 HK HK15101753.8A patent/HK1201263A1/zh unknown
- 2015-07-08 US US14/794,574 patent/US9744176B2/en active Active
-
2016
- 2016-06-10 HR HRP20160649TT patent/HRP20160649T1/hr unknown
- 2016-06-15 CY CY20161100522T patent/CY1117843T1/el unknown
-
2017
- 2017-07-26 US US15/660,694 patent/US10220044B2/en active Active
-
2018
- 2018-06-08 HK HK18107478.6A patent/HK1248214A1/zh unknown
-
2019
- 2019-01-10 US US16/245,131 patent/US10500212B2/en active Active
- 2019-10-30 US US16/668,555 patent/US10736904B2/en active Active
-
2020
- 2020-06-29 US US16/915,782 patent/US10980816B2/en active Active
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CO7091179A2 (es) | Nuevos derivados de tienopirimidina, procesos para su preparacion y sus usos terapeuticos | |
| PH12019500176A1 (en) | Heterocyclic compounds and ther uses | |
| CL2015001392A1 (es) | Compuestos y sus métodos de empleo | |
| CL2014003531A1 (es) | Suministro de farmaco diodegradable para las composiciones hidrofóbicas y su metodo de preparacion. | |
| CO7121320A2 (es) | Anticuerpos anti-hla-b*27 y usos de estos | |
| BR112015008272A2 (pt) | cápsula para preparação de bebidas | |
| UY34876A (es) | Anticuerpos anti-egfr y usos de los mismos | |
| CO7091175A2 (es) | Nuevos derivados de ácidos indaniloxidihidrobenzofuranilacéticos y sus usos como agonistas del receptor gpr40 | |
| CO7151485A2 (es) | Anticuerpos anti-sez6 y métodos de empleo | |
| MY167585A (en) | Disposable diaper | |
| UY34680A (es) | Anticuerpos humanos anti-cd27, métodos, y usos | |
| UY34782A (es) | Anticuerpos humanos para fel d1 y métodos para usarlos. | |
| BR112014026926A2 (pt) | uso terapêutico de produtos de semente de chardonnay | |
| CO7020877A2 (es) | Anticuerpos anti-asic1 y usos de los mismos | |
| PT2815769T (pt) | Fam19a5 para utilização no diagnóstico e tratamento de lesões do snc | |
| AR092198A1 (es) | Derivados de pirazolopirimidinas | |
| MY166103A (en) | Disposable diaper | |
| CO6910193A2 (es) | Derivados de anilina, su preparación y su aplicación terapéutica | |
| MX2015012416A (es) | Compuestos heterociclicos y sus usos. | |
| BR112014026326A2 (pt) | composição para tratamento de distúrbios metabólicos | |
| DK3030272T3 (da) | Fremgangsmåde til enzymatisk behandling af vævsprodukter | |
| UY34604A (es) | Inhibidores de oxadiazol de la producción de leucotrienos para terapia de combinación | |
| CO6900142A2 (es) | Derivados de etinilo como moduladores del receptor metatrópico de glutamato | |
| CO6880061A2 (es) | Método para tratar el cáncer mediante el uso combinado de fármacos | |
| CO7020916A2 (es) | Utilizacion en terapeutica de derivados de imidazopiridina |