CO7061069A2 - Glucosaminoglucanos no anticogulantes que comprenden una unidad de repetición de disacárido y su uso médico - Google Patents

Glucosaminoglucanos no anticogulantes que comprenden una unidad de repetición de disacárido y su uso médico

Info

Publication number
CO7061069A2
CO7061069A2 CO14129964A CO14129964A CO7061069A2 CO 7061069 A2 CO7061069 A2 CO 7061069A2 CO 14129964 A CO14129964 A CO 14129964A CO 14129964 A CO14129964 A CO 14129964A CO 7061069 A2 CO7061069 A2 CO 7061069A2
Authority
CO
Colombia
Prior art keywords
anticogulant
glycosaminoglycans
repeat unit
medical use
disaccharide repeat
Prior art date
Application number
CO14129964A
Other languages
English (en)
Inventor
Hans-Peter Ekre
Peter-Olov Eriksson
Ulf Lindhal
Erik Holmer
Original Assignee
Dilafor Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=48668970&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CO7061069(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Dilafor Ab filed Critical Dilafor Ab
Publication of CO7061069A2 publication Critical patent/CO7061069A2/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/727—Heparin; Heparan
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0075—Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/04—Drugs for genital or sexual disorders; Contraceptives for inducing labour or abortion; Uterotonics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/06—Antiabortive agents; Labour repressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Materials Engineering (AREA)
  • Polymers & Plastics (AREA)
  • Biochemistry (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
CO14129964A 2011-12-19 2014-06-16 Glucosaminoglucanos no anticogulantes que comprenden una unidad de repetición de disacárido y su uso médico CO7061069A2 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201161577223P 2011-12-19 2011-12-19

Publications (1)

Publication Number Publication Date
CO7061069A2 true CO7061069A2 (es) 2014-09-19

Family

ID=48668970

Family Applications (1)

Application Number Title Priority Date Filing Date
CO14129964A CO7061069A2 (es) 2011-12-19 2014-06-16 Glucosaminoglucanos no anticogulantes que comprenden una unidad de repetición de disacárido y su uso médico

Country Status (28)

Country Link
US (1) US9475888B2 (es)
EP (1) EP2794665B1 (es)
JP (2) JP6543467B2 (es)
KR (1) KR102135485B1 (es)
CN (1) CN104144950B (es)
AU (1) AU2012354229B2 (es)
BR (1) BR112014014454B1 (es)
CA (1) CA2856492C (es)
CL (1) CL2014001651A1 (es)
CO (1) CO7061069A2 (es)
CY (1) CY1119899T1 (es)
DK (1) DK2794665T3 (es)
ES (1) ES2656613T3 (es)
HK (1) HK1202883A1 (es)
HR (1) HRP20180124T1 (es)
HU (1) HUE036523T2 (es)
IL (1) IL232905A (es)
LT (1) LT2794665T (es)
ME (1) ME02994B (es)
MX (1) MX351104B (es)
NO (1) NO2904345T3 (es)
PL (1) PL2794665T3 (es)
PT (1) PT2794665T (es)
RS (1) RS56874B1 (es)
RU (1) RU2617764C2 (es)
SI (1) SI2794665T1 (es)
WO (1) WO2013095279A1 (es)
ZA (1) ZA201403640B (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013095215A1 (en) 2011-12-19 2013-06-27 Dilaforette Ab Low anticoagulant heparins
MX2014011451A (es) * 2012-03-26 2014-11-10 Dilafor Ab Procedimiento de tratamiento de la interrupcion del parto.
WO2013147689A1 (en) * 2012-03-26 2013-10-03 Dilafor Ab Combination treatment comprising sulphated glycosaminoglycans for inducing labor
UA117912C2 (uk) * 2012-05-08 2018-10-25 Ділафор Аб Застосування гепарину або гепарансульфату для лікування післяпологової кровотечі (ппк)
GB2515315A (en) 2013-06-19 2014-12-24 Dilafor Ab New Processes
CN103788222B (zh) * 2014-01-08 2016-08-31 中国科学院昆明植物研究所 Fuc3S4S取代的低聚糖胺聚糖及其制备方法
AU2015253870B2 (en) * 2014-04-30 2019-08-22 Agency For Science, Technology And Research Heparan sulphates
CN108424474B (zh) * 2017-02-15 2023-07-25 清华大学 去抗凝肝素衍生物及其用于炎症性肠病的治疗
WO2021165240A1 (en) 2020-02-17 2021-08-26 Dilafor Ab Tafoxiparin for the treatment of preeclampsia
EP4272749A1 (en) 2022-05-03 2023-11-08 Dilafor AB New medical use of tafoxiparin
WO2023213788A1 (en) 2022-05-03 2023-11-09 Dilafor Ab New medical use of tafoxiparin

Family Cites Families (53)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1136620A (en) 1979-01-08 1982-11-30 Ulf P.F. Lindahl Heparin fragments having selective anticoagulation activity
JPS63246396A (ja) * 1987-03-31 1988-10-13 Shiseido Co Ltd モノクロ−ナル抗体
FR2614026B1 (fr) * 1987-04-16 1992-04-17 Sanofi Sa Heparines de bas poids moleculaire, a structure reguliere, leur preparation et leurs applications biologiques
SE9002550D0 (sv) 1990-08-01 1990-08-01 Kabivitrum Ab Heparinfragment
SE9003181D0 (sv) 1990-10-04 1990-10-04 Kabivitrum Ab Use of heparin fraction
US5280016A (en) 1991-03-29 1994-01-18 Glycomed Incorporated Non-anticoagulant heparin derivatives
US5250519A (en) 1991-03-29 1993-10-05 Glycomed Incorporated Non-anticoagulant heparin derivatives
JPH0532703A (ja) * 1991-07-26 1993-02-09 Terumo Corp 低分子量ヘパリン誘導体の製造法
WO1994008595A1 (en) * 1992-10-13 1994-04-28 Virginia Commonwealth University Use of non-anticoagulant heparin for treating ischemia/reperfusion injury
US5527785A (en) 1993-05-14 1996-06-18 The Regents Of The University Of California Selectin receptor modulating compositions
US5744457A (en) * 1995-03-31 1998-04-28 Hamilton Civic Hospitals Research Development Inc. Compositions and methods for inhibiting thrombogenesis
DE69623840D1 (de) * 1995-03-31 2002-10-31 Hamilton Civic Hospitals Res Zusammensetzung zur Hemmung der Thromboseentstehung
US5993810A (en) 1996-03-15 1999-11-30 Lebovitz; Shamir Israel Method of softening or ripening the cervix of a female mammal using collagenase
US5767269A (en) * 1996-10-01 1998-06-16 Hamilton Civic Hospitals Research Development Inc. Processes for the preparation of low-affinity, low molecular weight heparins useful as antithrombotics
JP4203611B2 (ja) 1996-10-15 2009-01-07 生化学工業株式会社 子宮頸管熟化剤
GB9711443D0 (en) * 1997-06-03 1997-07-30 Leo Pharm Prod Ltd Chemical suppositions
US6569840B1 (en) * 1997-11-20 2003-05-27 Ikuo Yamashina Low-molecular heparin modification and remedy for skin ulcer
US6596705B1 (en) 1998-02-09 2003-07-22 The Regents Of The University Of California Inhibition of L-selectin and P-selection mediated binding using heparin
US6498246B1 (en) 1998-02-26 2002-12-24 Seikagaku Corporation Glycosaminoglycan derivatives and processes for preparing same
US6028061A (en) 1998-06-18 2000-02-22 Children's Medical Center Corp Angiogenesis inhibitors and use thereof
US6492503B1 (en) * 1998-07-31 2002-12-10 Seikagaku Corporation Glycosaminoglycan and drug compositions containing the same
EP1105733A1 (en) * 1998-08-26 2001-06-13 The Collaborative Group, Ltd. Receptor for underivatized, aqueous soluble beta-(1,3)-glucan
MXPA02000142A (es) * 1999-06-30 2003-07-21 Hamilton Civic Hospitals Res Composiciones de heparina que inhiben los factores de coagulacion asociados con el coagulo.
JP4897991B2 (ja) * 1999-07-23 2012-03-14 ラボラトリオス ファルマセウティコス ロビ ソシエダッド アノニマ 超低分子量ヘパリン組成物
IT1316986B1 (it) 2000-01-25 2003-05-26 Sigma Tau Ind Farmaceuti Derivati glicosamminoglicani parzialmente desolfatati nonanticoagulanti ad attivita' antiangiogenica.
JP4585072B2 (ja) * 2000-02-29 2010-11-24 扶桑薬品工業株式会社 ヘパリン解重合法、解重合ヘパリン、その誘導体および医薬組成物
ES2324701T3 (es) * 2000-09-12 2009-08-13 Massachusetts Institute Of Technology Metodos y productos relacionados con heparina de peso molecular bajo.
SE521676C2 (sv) * 2002-01-02 2003-11-25 Dilafor Ab Användning av glykosaminoglykaner för prevention och behandling av värksvaghet vid fullgången graviditet
EP1542704A1 (en) 2002-04-18 2005-06-22 Stephen H. Embury Method and composition for preventing pain in sickle cell patients
US8071569B2 (en) 2002-09-20 2011-12-06 Mousa Shaker A Oxidized heparin fractions and their use in inhibiting angiogenesis
JP2005106694A (ja) * 2003-09-30 2005-04-21 Mochida Pharmaceut Co Ltd 敗血症早期検出及び重篤度評価
EP1582531A1 (en) 2004-03-24 2005-10-05 Aventis Pharma S.A. Process for oxidizing unfractionated heparins and detecting presence or absence of glycoserine in heparin and heparin products
US20060040896A1 (en) * 2004-08-18 2006-02-23 Paringenix, Inc. Method and medicament for anticoagulation using a sulfated polysaccharide with enhanced anti-inflammatory activity
US7741311B2 (en) 2005-01-03 2010-06-22 Shaker Mousa Composition and method for treating occlusive vascular diseases, nerve regeneration, and wound healing
EP1906974A4 (en) * 2005-07-22 2010-06-23 Univ California SELECTINE INHIBITOR HEPARIN COMPOSITIONS
CA2616230A1 (en) 2005-07-22 2007-02-01 Trf Pharma, Inc. Method for treating sickle cell disease and sickle cell disease sequelae
CN101438146B (zh) * 2006-04-04 2014-12-10 神谷来克斯公司 高灵敏标志物分析和分子检测的方法和组合物
WO2007140231A2 (en) * 2006-05-25 2007-12-06 Momenta Pharmaceutical, Inc. Low molecular weight heparin composition and uses thereof
WO2009007224A1 (en) * 2007-07-10 2009-01-15 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Low molecular weight heparin derivatives having neuroprotective activity
CA2703848C (en) * 2007-11-02 2016-10-11 Momenta Pharmaceuticals, Inc. Non-anticoagulant polysaccharide compositions
US8569262B2 (en) 2007-11-02 2013-10-29 Momenta Pharmaceuticals, Inc. Polysaccharide compositions and methods of use for the treatment and prevention of disorders associated with progenitor cell mobilization
US8592393B2 (en) * 2007-11-02 2013-11-26 Momenta Pharmaceuticals, Inc. Polysaccharide compositions and methods of use for the treatment and prevention of disorders associated with progenitor cell mobilization
WO2009059284A2 (en) 2007-11-02 2009-05-07 Momenta Pharmaceuticals, Inc. Non-anticoagulant polysaccharide compositions
WO2009073184A1 (en) 2007-12-03 2009-06-11 Florida State University Research Foundation, Inc. Compositions for inducing labor and associated methods
JP5758797B2 (ja) 2008-04-04 2015-08-05 ユニバーシティ・オブ・ユタ・リサーチ・ファウンデイション アルキル化半合成グリコサミノグリカンエーテルならびにその製造および使用方法
JP2012522074A (ja) * 2009-03-27 2012-09-20 アクタマックス サージカル マテリアルズ リミテッド ライアビリティ カンパニー ポリグリセロールアルデヒド
EP2419736B1 (en) 2009-04-16 2014-01-29 Momenta Pharmaceuticals, Inc. Methods of assessing activity of a polysaccharide composition
AU2010268756A1 (en) 2009-06-30 2012-01-19 The Walter And Eliza Hall Institute Of Medical Research Sulfated polysaccharides having antiplasmodial activity and methods and products for identifying antiplasmodial activity
SG178119A1 (en) * 2009-07-31 2012-03-29 Bayer Healthcare Llc Modified factor ix polypeptides and uses thereof
AU2010334412B2 (en) * 2009-12-22 2016-02-04 Lifebond Ltd Modification of enzymatic crosslinkers for controlling properties of crosslinked matrices
WO2013095215A1 (en) 2011-12-19 2013-06-27 Dilaforette Ab Low anticoagulant heparins
WO2013147689A1 (en) 2012-03-26 2013-10-03 Dilafor Ab Combination treatment comprising sulphated glycosaminoglycans for inducing labor
MX2014011451A (es) 2012-03-26 2014-11-10 Dilafor Ab Procedimiento de tratamiento de la interrupcion del parto.

Also Published As

Publication number Publication date
WO2013095279A1 (en) 2013-06-27
PL2794665T3 (pl) 2018-04-30
EP2794665A4 (en) 2015-08-26
ES2656613T3 (es) 2018-02-27
DK2794665T3 (da) 2018-01-29
KR20140113652A (ko) 2014-09-24
HRP20180124T1 (hr) 2018-02-23
RU2014129816A (ru) 2016-02-20
EP2794665A1 (en) 2014-10-29
KR102135485B1 (ko) 2020-07-17
US9475888B2 (en) 2016-10-25
AU2012354229B2 (en) 2016-12-01
JP6543467B2 (ja) 2019-07-10
HK1202883A1 (en) 2015-10-09
CN104144950B (zh) 2017-09-05
MX2014007122A (es) 2015-03-05
IL232905A0 (en) 2014-07-31
CL2014001651A1 (es) 2014-10-10
BR112014014454A2 (pt) 2017-06-13
CY1119899T1 (el) 2018-06-27
LT2794665T (lt) 2017-12-27
JP2018111825A (ja) 2018-07-19
US20150011505A1 (en) 2015-01-08
RU2617764C2 (ru) 2017-04-26
JP2015500388A (ja) 2015-01-05
AU2012354229A1 (en) 2014-06-05
CA2856492C (en) 2017-01-10
SI2794665T1 (en) 2018-03-30
NO2904345T3 (es) 2018-07-21
CA2856492A1 (en) 2013-06-27
IL232905A (en) 2017-02-28
PT2794665T (pt) 2018-01-24
ZA201403640B (en) 2017-06-28
EP2794665B1 (en) 2017-11-22
ME02994B (me) 2018-10-20
CN104144950A (zh) 2014-11-12
BR112014014454B1 (pt) 2021-03-09
RS56874B1 (sr) 2018-04-30
MX351104B (es) 2017-10-02
HUE036523T2 (hu) 2018-07-30

Similar Documents

Publication Publication Date Title
CO7061069A2 (es) Glucosaminoglucanos no anticogulantes que comprenden una unidad de repetición de disacárido y su uso médico
CO6900149A2 (es) Una composición farmacéutica que comprende los fitocanabinoides canabidivarina (cbdv) y canabidiol (cbd)
CO6801774A2 (es) Compuestos de benzotiazol y su uso farmacéutico
BR302012001342S1 (pt) Configuração aplicada em instrumento médico
BR112012013148A2 (pt) formulação farmacêutica e uso
CO6990717A2 (es) Derivados de dihidro-benzo-oxazina y dihidro-pirido-oxazina
BRDI7103743S (pt) Configuração aplicada em instrumento médico
BRPI1010682A2 (pt) dispositivo de exibição estereoscópica e método para acionar o mesmo
BRDI7106721S (pt) Configuração aplicada em instrumento médico
FI20116089L (fi) Järjestely ja laite
BR112013015143A2 (pt) artigo absorvente que compreende complexo de ciclodextrina
BR302012001336S1 (pt) Configuração aplicada em instrumento médico
BR302012001341S1 (pt) Configuração aplicada em instrumento médico
FI20090142A0 (fi) Uudet menetelmät ja tuotteet
BR112014010157A2 (pt) adaptação da linguagem usada em um dispositivo
BRDI7104785S (pt) Configuração aplicada em instrumento médico
BRDI7104782S (pt) Configuração aplicada em instrumento médico
BRDI7104784S (pt) Configuração aplicada em instrumento médico
BR302012003127S1 (pt) Configuração aplicada em instrumento médico
FI10901U1 (fi) Desinfiointi- ja/tai sterilointilaite
BR112013014031A2 (pt) artigo absorvente que compreende complexo de ciclodextrina
CO7010828A2 (es) Preparación farmacéutica que comprende ߖciclodextrina sustituida
BR112014015298A8 (pt) derivados de aza-adamantano e usos dos mesmos
CO6990713A2 (es) Preparaciones que comprenden emodépsido amorfo
BRDI7106720S (pt) Configuração aplicada em instrumento médico