CO5721004A2 - Formas cristalinas novedosas de la sal de mesilato de 2,3-dimetil-8-(2,6-dimetilbencilamino)-n-hidroxietil-imidazol[1,2-a]piridin-6-carboxamida - Google Patents

Formas cristalinas novedosas de la sal de mesilato de 2,3-dimetil-8-(2,6-dimetilbencilamino)-n-hidroxietil-imidazol[1,2-a]piridin-6-carboxamida

Info

Publication number
CO5721004A2
CO5721004A2 CO06059763A CO06059763A CO5721004A2 CO 5721004 A2 CO5721004 A2 CO 5721004A2 CO 06059763 A CO06059763 A CO 06059763A CO 06059763 A CO06059763 A CO 06059763A CO 5721004 A2 CO5721004 A2 CO 5721004A2
Authority
CO
Colombia
Prior art keywords
hydroxyethyl
dimethyl
carboxamide
dimethylbyncilamine
novedous
Prior art date
Application number
CO06059763A
Other languages
English (en)
Inventor
Lars Lilljequist
Maria Lindkvist
Peter Nordberg
Ursula Pettersson
Tesfai Sebhatu
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=30768770&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CO5721004(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of CO5721004A2 publication Critical patent/CO5721004A2/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Epidemiology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

1.- La sal de mesilato de 2,3-dimetil-8-(2,6-dimetilbencilamino)-N-hidroxietil-imidazo[1,2-a]piridin-6-carboxamida y las formas cristalinas de la misma.2.- Un compuesto de acuerdo con la reivindicacion 1 en donde la forma cristalina es la forma A de la sal de mesilato de 2,3-dimetil-8-(2,6-dimetilbencilamino)-N-hidroxietil-imidazo[1,2-a]piridin-6-carboxamida, caracterizada por una celda unitaria triclinica con los parametros:a = 8.6 , b = 18.7 , c = 15.8 , a = 90°, ß = 113°, ? = 90°.3.- Un compuesto de acuerdo con la reivindicacion 1, en donde la forma cristalina es la forma A de la sal de mesilato de 2,3-dimetil-8-(2,6dimetilbencilamino)-N-hidroxietil-imidazo[1.2-a]piridin-6-carboxamida, caracterizada por proveer un patron de difraccion de rayos X mostrando sustancialmente los siguientes valores d:4.- Un compuesto de acuerdo con la reivindicacion 1, en donde la forma cristalina es la forma A de la sal de mesilato de 2,3-dimetil-8-(2,6-dimetilbencilamino)-N-hidroxietil-imidazo[1,2-a]piridin-6-carboxamida.
CO06059763A 2003-12-18 2006-06-20 Formas cristalinas novedosas de la sal de mesilato de 2,3-dimetil-8-(2,6-dimetilbencilamino)-n-hidroxietil-imidazol[1,2-a]piridin-6-carboxamida CO5721004A2 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE0303451A SE0303451D0 (sv) 2003-12-18 2003-12-18 New compounds

Publications (1)

Publication Number Publication Date
CO5721004A2 true CO5721004A2 (es) 2007-01-31

Family

ID=30768770

Family Applications (1)

Application Number Title Priority Date Filing Date
CO06059763A CO5721004A2 (es) 2003-12-18 2006-06-20 Formas cristalinas novedosas de la sal de mesilato de 2,3-dimetil-8-(2,6-dimetilbencilamino)-n-hidroxietil-imidazol[1,2-a]piridin-6-carboxamida

Country Status (25)

Country Link
US (1) US7459463B2 (es)
EP (1) EP1697360B1 (es)
JP (2) JP2007514744A (es)
KR (1) KR20060125803A (es)
CN (1) CN1894246B (es)
AR (1) AR046956A1 (es)
AT (1) ATE499371T1 (es)
AU (1) AU2004299435B2 (es)
BR (1) BRPI0417640A (es)
CA (1) CA2549144A1 (es)
CO (1) CO5721004A2 (es)
DE (1) DE602004031556D1 (es)
ES (1) ES2359829T3 (es)
HK (1) HK1095810A1 (es)
IL (1) IL175957A0 (es)
MX (1) MXPA06006708A (es)
MY (1) MY140450A (es)
NO (1) NO20063309L (es)
RU (1) RU2376306C2 (es)
SE (1) SE0303451D0 (es)
TW (1) TW200526659A (es)
UA (1) UA84443C2 (es)
UY (1) UY28676A1 (es)
WO (1) WO2005058895A1 (es)
ZA (1) ZA200604633B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005041961A1 (en) * 2003-11-03 2005-05-12 Astrazeneca Ab Imidazo [1,2-a] pyridine derivatives for the treatment of silent gastro-esophageal reflux
FI20086158A0 (fi) 2008-12-03 2008-12-03 Mikael Dahlstroem Imidatsopyridiinijohdannaiset

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4040632A1 (de) * 1990-12-19 1992-06-25 Kali Chemie Pharma Gmbh Phenylalkylaminoalkyl-verbindungen sowie verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
SE512531C2 (sv) * 1997-09-04 2000-03-27 Astacarotene Ab Användning av åtminstone en typ av xantofyller för framställning av ett läkemedel för profylaktisk och/eller terapeutisk förbättring av muskelfunktionsdurationen hos däggdjur och/eller behandling av muskelstörningar eller - sjukdomar hos däggdjur
SE9801526D0 (sv) 1998-04-29 1998-04-29 Astra Ab New compounds
SE0003186D0 (sv) * 2000-09-07 2000-09-07 Astrazeneca Ab New process
SE0100296D0 (sv) * 2001-02-01 2001-02-01 Astrazeneca Ab New compounds
SE0100295D0 (sv) * 2001-02-01 2001-02-01 Astrazeneca Ab New compounds
SE0100297D0 (sv) * 2001-02-01 2001-02-01 Astrazeneca Ab New compounds
BR0206825A (pt) * 2001-02-13 2004-02-25 Astrazeneca Ab Formulação de dispersão sólida de liberação modificada, multiparticulada, processo para a preparação da formulação, uso da mesma, tablete, e, métodos para o tratamento de uma doença cardiovascular, e, para o tratamento de câncer
BR0309808A (pt) * 2002-05-07 2005-03-01 Altana Pharma Ag Combinação para o tratamento de distúrbios das vias aéreas

Also Published As

Publication number Publication date
WO2005058895A1 (en) 2005-06-30
UY28676A1 (es) 2005-07-29
UA84443C2 (ru) 2008-10-27
RU2006123362A (ru) 2008-01-27
MXPA06006708A (es) 2006-08-18
US20070112021A1 (en) 2007-05-17
JP2012102143A (ja) 2012-05-31
AU2004299435B2 (en) 2008-04-17
ATE499371T1 (de) 2011-03-15
KR20060125803A (ko) 2006-12-06
US7459463B2 (en) 2008-12-02
CN1894246A (zh) 2007-01-10
AR046956A1 (es) 2006-01-04
CN1894246B (zh) 2011-06-22
TW200526659A (en) 2005-08-16
SE0303451D0 (sv) 2003-12-18
EP1697360A1 (en) 2006-09-06
RU2376306C2 (ru) 2009-12-20
EP1697360B1 (en) 2011-02-23
ZA200604633B (en) 2007-04-25
HK1095810A1 (es) 2007-05-18
BRPI0417640A (pt) 2007-03-27
AU2004299435A1 (en) 2005-06-30
MY140450A (en) 2009-12-31
CA2549144A1 (en) 2005-06-30
IL175957A0 (en) 2006-10-05
NO20063309L (no) 2006-09-14
JP2007514744A (ja) 2007-06-07
DE602004031556D1 (de) 2011-04-07
ES2359829T3 (es) 2011-05-27

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