CO5160266A1 - Nuevos agentes antibacterianos de isoxazolinona - Google Patents
Nuevos agentes antibacterianos de isoxazolinonaInfo
- Publication number
- CO5160266A1 CO5160266A1 CO99053191A CO99053191A CO5160266A1 CO 5160266 A1 CO5160266 A1 CO 5160266A1 CO 99053191 A CO99053191 A CO 99053191A CO 99053191 A CO99053191 A CO 99053191A CO 5160266 A1 CO5160266 A1 CO 5160266A1
- Authority
- CO
- Colombia
- Prior art keywords
- isoxazolinona
- antibacterial agents
- new antibacterial
- new
- isoxazolinones
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
- C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
- C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
- C07D261/10—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D261/12—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
Abstract
Esta invención describe derivados de isoxazolina que poseen actividad antibacteriana y son útiles en el tratamiento de enfermedades bacterianas. En forma más particular, se proporcionan nuevas isoxazolinonas que tienen la fórmula general:<EMI FILE="99053191_1" ID="1" IMF=JPEG >en donde A y R1 son como se describen en la especificación.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US9757498P | 1998-08-24 | 1998-08-24 |
Publications (1)
Publication Number | Publication Date |
---|---|
CO5160266A1 true CO5160266A1 (es) | 2002-05-30 |
Family
ID=22264103
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CO99053191A CO5160266A1 (es) | 1998-08-24 | 1999-08-23 | Nuevos agentes antibacterianos de isoxazolinona |
Country Status (22)
Country | Link |
---|---|
EP (1) | EP1107756A4 (es) |
JP (1) | JP2002523369A (es) |
KR (1) | KR20010072945A (es) |
CN (1) | CN1314813A (es) |
AR (1) | AR020250A1 (es) |
AU (1) | AU748750B2 (es) |
BR (1) | BR9913225A (es) |
CA (1) | CA2341271A1 (es) |
CO (1) | CO5160266A1 (es) |
CZ (1) | CZ2001669A3 (es) |
HU (1) | HUP0103433A3 (es) |
ID (1) | ID27690A (es) |
IL (1) | IL141542A0 (es) |
NO (1) | NO20010916L (es) |
NZ (1) | NZ509867A (es) |
PE (1) | PE20001063A1 (es) |
PL (1) | PL346267A1 (es) |
TR (1) | TR200100672T2 (es) |
TW (1) | TW572757B (es) |
UY (1) | UY25677A1 (es) |
WO (1) | WO2000010566A1 (es) |
ZA (1) | ZA200101505B (es) |
Families Citing this family (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6465456B2 (en) * | 2000-06-29 | 2002-10-15 | Bristol-Myers Squibb Company | Isoxazolinone antibacterial agents |
JP2002020366A (ja) * | 2000-07-05 | 2002-01-23 | Sumitomo Seika Chem Co Ltd | アルキルチオフェニル酢酸類の製造方法 |
PE20020689A1 (es) | 2000-11-17 | 2002-08-03 | Upjohn Co | Oxazolidinonas con un heterociclo de 6 o 7 miembros unidos con enlace anular al benceno |
PE20030044A1 (es) * | 2000-11-17 | 2003-02-09 | Upjohn Co | Isoxazolinonas biciclicas de formula i |
US6861433B2 (en) | 2000-12-15 | 2005-03-01 | Pharmacia & Upjohn Company | Oxazolidinone photoaffinity probes |
CA2424402A1 (en) | 2000-12-21 | 2002-08-01 | Pharmacia & Upjohn Company | Antimicrobial quinolone derivatives and use of the same to treat bacterial infections |
ES2180456B1 (es) * | 2001-07-20 | 2004-05-01 | Laboratorios S.A.L.V.A.T., S.A. | Isoxazoles sustituidos y su utilizacion como antibioticos. |
WO2003031443A1 (en) | 2001-10-04 | 2003-04-17 | Morphochem Aktiengesellschaft für kombinatorische Chemie | Dual actions antibiotics comprising a oxazoldinone and a quinolone or naphthyridinone moiety |
EP1443930A1 (en) | 2001-10-25 | 2004-08-11 | AstraZeneca AB | Isoxazoline derivatives useful as antimicrobials |
US6875784B2 (en) | 2002-10-09 | 2005-04-05 | Pharmacia & Upjohn Company | Antimibicrobial [3.1.0.] bicyclic oxazolidinone derivatives |
US7105547B2 (en) | 2002-10-10 | 2006-09-12 | Pharmacia And Upjohn Company | Antimicrobial 1-aryl dihydropyridone compounds |
EP1594865A2 (en) * | 2003-02-07 | 2005-11-16 | Warner-Lambert Company LLC | Antibacterial agents |
JP4805139B2 (ja) | 2003-04-30 | 2011-11-02 | モルホケム アクツィエンゲゼルシャフト フューア コンビナートリッシュ ヒェミー | 炭疽および他の感染を治療するためのオキサゾリジノン‐キノリンハイブリッド抗生物質の使用 |
EP2492264A3 (en) | 2003-06-03 | 2012-12-19 | Rib-X Pharmaceuticals, Inc. | Biaryl Heterocyclic Compounds And Methods Of Making And Using The Same |
US8324398B2 (en) | 2003-06-03 | 2012-12-04 | Rib-X Pharmaceuticals, Inc. | Process for the synthesis of biaryl oxazolidinones |
CN100457742C (zh) * | 2003-06-03 | 2009-02-04 | 瑞伯-X医药品有限公司 | 联芳基杂环化合物的制备和用途 |
WO2005012270A2 (en) * | 2003-07-29 | 2005-02-10 | Rib-X Pharmaceuticals, Inc. | Biaryl heterocyclic amines, amides, and sulfur-containing compounds and methods of making and using the same |
DE10340485B4 (de) * | 2003-09-03 | 2015-05-13 | Morphochem AG Aktiengesellschaft für kombinatorische Chemie | Verfahren zur Herstellung von Oxazolidinon-Chinolon Hybriden |
US7304050B2 (en) * | 2003-09-16 | 2007-12-04 | Pfizer Inc. | Antibacterial agents |
EP1713785A1 (en) | 2003-12-17 | 2006-10-25 | Rib-X Pharmaceuticals, Inc. | Halogenated biaryl heterocyclic compounds and methods of making and using the same |
PT1709044E (pt) | 2003-12-18 | 2008-10-27 | Morphochem Aktiengese Fur Komb | Antibióticos híbridos de oxazolidinona-quinolona |
US8158797B2 (en) | 2003-12-18 | 2012-04-17 | Morphochem Aktiengesellschaft Fur Kombinatorische Chemie | Oxazolidinone-quinolone hybrid antibiotics |
WO2005082900A2 (en) * | 2004-01-28 | 2005-09-09 | Pharmacia & Upjohn Company Llc | Oxazolidinone amidoximes as antibacterial agents |
WO2006133397A2 (en) | 2005-06-08 | 2006-12-14 | Rib-X Pharmaceuticals, Inc. | Process for the synthesis of triazoles |
AT503354B1 (de) * | 2006-02-22 | 2008-07-15 | Dsm Fine Chem Austria Gmbh | Verfahren zur herstellung von 3,4-disubstituierten phenylessigsäuren, sowie neue zwischenverbindungen |
JP4518066B2 (ja) * | 2006-10-25 | 2010-08-04 | 宇部興産株式会社 | ジアルコキシニトリル誘導体及びその製法 |
CN110423610B (zh) * | 2019-08-29 | 2023-05-12 | 浙江理工大学 | 一种检测双光子汞离子荧光探针及其制备方法与使用方法 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2045049A1 (de) * | 1970-09-11 | 1972-03-23 | Dr Karl Thomae GmbH, 7950 Biberach | Neue Nitrofurandenvate und Ver fahren zu ihrer Herstellung |
US4000155A (en) * | 1975-12-11 | 1976-12-28 | Eli Lilly And Company | Herbicidal 2-methyl-4-phenyl-5-pyrazolinones[and isoxazolinones] |
DE69316240T2 (de) * | 1992-12-08 | 1998-05-20 | Upjohn Co | Durch eine tropon gruppe substituierte phenyloxazolidinone-derivate als antibakterielles mittel |
DK0863890T3 (da) * | 1995-09-15 | 2003-03-24 | Upjohn Co | 5-amidomethyl alfa, beta-mættede og -umættede 3-aryl-butyrolacetone antibakterielle midler |
GB9521508D0 (en) * | 1995-10-20 | 1995-12-20 | Zeneca Ltd | Chemical compounds |
DE69716925T2 (de) * | 1996-08-21 | 2003-09-11 | Upjohn Co | Isoxazoline derivate und ihre verwendung als antimikroben |
-
1999
- 1999-08-19 TW TW88114208A patent/TW572757B/zh active
- 1999-08-23 TR TR2001/00672T patent/TR200100672T2/xx unknown
- 1999-08-23 WO PCT/US1999/019265 patent/WO2000010566A1/en not_active Application Discontinuation
- 1999-08-23 CA CA002341271A patent/CA2341271A1/en not_active Abandoned
- 1999-08-23 KR KR1020017002377A patent/KR20010072945A/ko not_active Application Discontinuation
- 1999-08-23 CZ CZ2001669A patent/CZ2001669A3/cs unknown
- 1999-08-23 HU HU0103433A patent/HUP0103433A3/hu unknown
- 1999-08-23 IL IL14154299A patent/IL141542A0/xx unknown
- 1999-08-23 EP EP99945157A patent/EP1107756A4/en not_active Withdrawn
- 1999-08-23 JP JP2000565887A patent/JP2002523369A/ja active Pending
- 1999-08-23 AU AU57833/99A patent/AU748750B2/en not_active Ceased
- 1999-08-23 NZ NZ509867A patent/NZ509867A/en unknown
- 1999-08-23 ID IDW20010439A patent/ID27690A/id unknown
- 1999-08-23 CN CN99809894A patent/CN1314813A/zh active Pending
- 1999-08-23 CO CO99053191A patent/CO5160266A1/es unknown
- 1999-08-23 BR BR9913225-7A patent/BR9913225A/pt not_active IP Right Cessation
- 1999-08-23 PL PL99346267A patent/PL346267A1/xx not_active Application Discontinuation
- 1999-08-24 AR ARP990104229A patent/AR020250A1/es not_active Application Discontinuation
- 1999-08-24 UY UY25677A patent/UY25677A1/es unknown
- 1999-08-24 PE PE1999000853A patent/PE20001063A1/es not_active Application Discontinuation
-
2001
- 2001-02-22 ZA ZA200101505A patent/ZA200101505B/en unknown
- 2001-02-23 NO NO20010916A patent/NO20010916L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
NO20010916L (no) | 2001-04-10 |
EP1107756A4 (en) | 2003-02-26 |
AU748750B2 (en) | 2002-06-13 |
CN1314813A (zh) | 2001-09-26 |
PE20001063A1 (es) | 2000-12-24 |
HUP0103433A3 (en) | 2002-08-28 |
ID27690A (id) | 2001-04-19 |
ZA200101505B (en) | 2002-02-22 |
UY25677A1 (es) | 2001-08-27 |
KR20010072945A (ko) | 2001-07-31 |
JP2002523369A (ja) | 2002-07-30 |
AR020250A1 (es) | 2002-05-02 |
PL346267A1 (en) | 2002-01-28 |
HUP0103433A2 (hu) | 2002-01-28 |
CA2341271A1 (en) | 2000-03-02 |
AU5783399A (en) | 2000-03-14 |
NZ509867A (en) | 2003-08-29 |
TR200100672T2 (tr) | 2001-07-23 |
WO2000010566A1 (en) | 2000-03-02 |
EP1107756A1 (en) | 2001-06-20 |
IL141542A0 (en) | 2002-03-10 |
TW572757B (en) | 2004-01-21 |
BR9913225A (pt) | 2001-05-22 |
CZ2001669A3 (cs) | 2001-08-15 |
NO20010916D0 (no) | 2001-02-23 |
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