CO4960651A1 - Tabletas de metilcelulosa rapidamente desintegrables - Google Patents
Tabletas de metilcelulosa rapidamente desintegrablesInfo
- Publication number
- CO4960651A1 CO4960651A1 CO98047418A CO98047418A CO4960651A1 CO 4960651 A1 CO4960651 A1 CO 4960651A1 CO 98047418 A CO98047418 A CO 98047418A CO 98047418 A CO98047418 A CO 98047418A CO 4960651 A1 CO4960651 A1 CO 4960651A1
- Authority
- CO
- Colombia
- Prior art keywords
- mixture
- tablet
- andgt
- povidone
- viscosity
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/716—Glucans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/716—Glucans
- A61K31/717—Celluloses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2009—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/10—Laxatives
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Physiology (AREA)
- Nutrition Science (AREA)
- Zoology (AREA)
- Inorganic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
Abstract
El presente invento se refiere a una nueva composiciónfarmacéutica y a un procedimiento para preparar tabletas de metilcelulosa tragables, que se desintegran con rapidez y cumplen las normas de desintegración de la USP en ácido clorhídrico 0,1 N así como en agua. Una tableta rápidamente desintegrable para administración por vía oral, cuya tableta comprende una mezcla compactada de metilcelulosa que tiene una viscosidad de ANDgt;1.000 centipoises; y una sal de calcio comestible. Una tableta rápidamente desintegrable para administración por vía oral, cuya tableta comprende metilcelulosa que tiene una viscosidad de ANDgt; 3.000 centipoises; fosfato de calcio dibásico, lauril-sulfato de sodio, Povidone; almidón-glicolato de sodio, y estearato de magnesio. Un procedimiento para preparar una formulación de tableta que comprende compactar una mezcla obtenida de a) mezcladura conjunta para formar una mezcla intragranular de metilcelulosa de alta viscosidad ANDgt; 3.000 cps; un agente humectante, Povidone o almidón-glicolato de sodio, y una sal de calcio comestible; y b) añadir a la mezcla de la operación (a) una solución acuosa de PVP, o rociar alternativamente la mezcla de la operación a) con una solución acuosa de PVP; y preparar granulados; y c) mezclar conjuntamente una mezcla extragranular de una sal de calcio comestible, un agente humectante; un agente lubricante; Povidone o almidón-glicolato de sodio o una de sus mezclas; y d) compactar los granulados de la operación (b) con la mezcla extragranular de la operación (c)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US5689997P | 1997-08-22 | 1997-08-22 | |
US8766298P | 1998-06-02 | 1998-06-02 |
Publications (1)
Publication Number | Publication Date |
---|---|
CO4960651A1 true CO4960651A1 (es) | 2000-09-25 |
Family
ID=26735831
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CO98047418A CO4960651A1 (es) | 1997-08-22 | 1998-08-19 | Tabletas de metilcelulosa rapidamente desintegrables |
Country Status (16)
Country | Link |
---|---|
US (9) | US6350469B1 (es) |
EP (1) | EP1005329A4 (es) |
JP (1) | JP2001513545A (es) |
KR (3) | KR20070040424A (es) |
CN (2) | CN1660054A (es) |
AR (1) | AR017512A1 (es) |
AU (1) | AU741326B2 (es) |
BR (1) | BR9811980A (es) |
CA (1) | CA2301135C (es) |
CO (1) | CO4960651A1 (es) |
EA (1) | EA004803B1 (es) |
MY (2) | MY128046A (es) |
NZ (1) | NZ502891A (es) |
PL (1) | PL338858A1 (es) |
TW (1) | TWI222869B (es) |
WO (1) | WO1999009958A1 (es) |
Families Citing this family (35)
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AR016827A1 (es) | 1997-08-22 | 2001-08-01 | Smithkline Beecham Corp | PROCEDIMIENTO PARA LA PREPARACIoN DE UNA TABLETA FARMACÉUTICA |
AR017512A1 (es) * | 1997-08-22 | 2001-09-12 | Smithkline Beecham Corp | Tabletas de metilcelulosa rapidamente desintegrables para administracion por via oral y procedimiento para prepararlas |
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WO2000013667A1 (en) | 1998-09-08 | 2000-03-16 | Smithkline Beecham Corporation | Lipstatin derivative-soluble fiber tablets |
FR2795962B1 (fr) | 1999-07-08 | 2003-05-09 | Prographarm Laboratoires | Procede de fabrication de granules enrobes a gout masque et liberation immediate du principe actif |
FR2798289B1 (fr) * | 1999-09-15 | 2004-12-31 | Cll Pharma | Formes galeniques a delitement rapide en bouche et leur procede de preparation |
CN1196463C (zh) | 1999-12-20 | 2005-04-13 | 汉高两合股份公司 | 用于角蛋白纤维的固体染色剂 |
EP1239816B1 (de) | 1999-12-20 | 2007-11-21 | Henkel Kommanditgesellschaft auf Aktien | Festförmiges färbemittel für keratinfasern |
DE19961910A1 (de) | 1999-12-20 | 2001-06-21 | Henkel Kgaa | Färbemittel |
CN100387225C (zh) * | 1999-12-20 | 2008-05-14 | 汉高两合股份公司 | 稠化体系的制片方法 |
US6777000B2 (en) * | 2001-02-28 | 2004-08-17 | Carrington Laboratories, Inc. | In-situ gel formation of pectin |
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US20040197284A1 (en) * | 2003-04-04 | 2004-10-07 | Frederic Auguste | Cosmetic composition comprising a volatile fatty phase |
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KR100895942B1 (ko) * | 2007-05-08 | 2009-05-07 | 조선대학교산학협력단 | 생약 추출물을 함유하는 구강 내 속붕해성 제제 조성물 및그의 제조 방법 |
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-
1998
- 1998-08-18 AR ARP980104076A patent/AR017512A1/es unknown
- 1998-08-19 CO CO98047418A patent/CO4960651A1/es unknown
- 1998-08-20 MY MYPI98003811A patent/MY128046A/en unknown
- 1998-08-20 MY MYPI20034998A patent/MY135183A/en unknown
- 1998-08-21 WO PCT/US1998/017405 patent/WO1999009958A1/en not_active Application Discontinuation
- 1998-08-21 CA CA002301135A patent/CA2301135C/en not_active Expired - Fee Related
- 1998-08-21 CN CN2004100115143A patent/CN1660054A/zh active Pending
- 1998-08-21 KR KR1020077007455A patent/KR20070040424A/ko active Search and Examination
- 1998-08-21 PL PL98338858A patent/PL338858A1/xx unknown
- 1998-08-21 BR BR9811980-0A patent/BR9811980A/pt not_active Application Discontinuation
- 1998-08-21 JP JP2000507349A patent/JP2001513545A/ja active Pending
- 1998-08-21 KR KR1020077027417A patent/KR20070116291A/ko not_active Application Discontinuation
- 1998-08-21 EA EA200000246A patent/EA004803B1/ru not_active IP Right Cessation
- 1998-08-21 NZ NZ502891A patent/NZ502891A/en unknown
- 1998-08-21 US US09/485,627 patent/US6350469B1/en not_active Expired - Lifetime
- 1998-08-21 AU AU92022/98A patent/AU741326B2/en not_active Ceased
- 1998-08-21 EP EP98944489A patent/EP1005329A4/en active Pending
- 1998-08-21 CN CN988102943A patent/CN1215833C/zh not_active Expired - Fee Related
- 1998-08-21 TW TW087113834A patent/TWI222869B/zh not_active IP Right Cessation
- 1998-08-21 KR KR1020007001825A patent/KR100743767B1/ko not_active IP Right Cessation
-
2001
- 2001-12-19 US US10/024,807 patent/US20020086052A1/en not_active Abandoned
-
2003
- 2003-06-19 US US10/464,968 patent/US20030215505A1/en not_active Abandoned
-
2004
- 2004-11-19 US US10/993,458 patent/US20050089561A1/en not_active Abandoned
- 2004-11-19 US US10/993,984 patent/US20050089565A1/en not_active Abandoned
- 2004-11-19 US US10/993,983 patent/US20050089564A1/en not_active Abandoned
- 2004-11-19 US US10/993,550 patent/US20050089563A1/en not_active Abandoned
- 2004-11-19 US US10/993,272 patent/US20050089560A1/en not_active Abandoned
- 2004-11-19 US US10/993,547 patent/US7125562B2/en not_active Expired - Lifetime
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