FR2858556B1 - Composition pharmaceutique solide dispersible et/ou orodispersible non pelliculee contenant au moins le principe actif metformine, et procede de preparation - Google Patents
Composition pharmaceutique solide dispersible et/ou orodispersible non pelliculee contenant au moins le principe actif metformine, et procede de preparationInfo
- Publication number
- FR2858556B1 FR2858556B1 FR0350403A FR0350403A FR2858556B1 FR 2858556 B1 FR2858556 B1 FR 2858556B1 FR 0350403 A FR0350403 A FR 0350403A FR 0350403 A FR0350403 A FR 0350403A FR 2858556 B1 FR2858556 B1 FR 2858556B1
- Authority
- FR
- France
- Prior art keywords
- pelletized
- dispersible
- preparing
- pharmaceutical composition
- active ingredient
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
Priority Applications (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0350403A FR2858556B1 (fr) | 2003-08-06 | 2003-08-06 | Composition pharmaceutique solide dispersible et/ou orodispersible non pelliculee contenant au moins le principe actif metformine, et procede de preparation |
JP2006522382A JP2007501205A (ja) | 2003-08-06 | 2004-08-05 | 少なくともメトホルミン活性成分を含有する非フィルムコーティーング分散性および/または口内分散性固形調合組成物、およびその製造方法 |
CA002535026A CA2535026A1 (fr) | 2003-08-06 | 2004-08-05 | Composition pharmaceutique solide dispersible et/ou orodispersible non pelliculee contenant au moins le principe actif metformine, et procede de preparation |
AU2004262964A AU2004262964A1 (en) | 2003-08-06 | 2004-08-05 | Solid dispersible and/or orodispersible non-filmy containing at least one type of active substance pharmaceutical composition and method for the preparation thereof |
PCT/FR2004/050376 WO2005013957A2 (fr) | 2003-08-06 | 2004-08-05 | Composition pharmaceutique solide dispersible et/ou orodispersible non pelliculee contenant au moins le principe actif metformine, et procede de preparation |
EP04786374A EP1653936A2 (fr) | 2003-08-06 | 2004-08-05 | Composition pharmaceutique solide dispersible et/ou orodispersible non pelliculee contenant au moins le principe actif metformine, et procede de preparation |
US10/567,345 US20070218129A1 (en) | 2003-08-06 | 2004-08-05 | Solid Dispersible and/or Orodispersible Non-Filmy Containing at Least One Type of Active Substance Pharmaceutical Composition and Method for the Preparation Thereof |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0350403A FR2858556B1 (fr) | 2003-08-06 | 2003-08-06 | Composition pharmaceutique solide dispersible et/ou orodispersible non pelliculee contenant au moins le principe actif metformine, et procede de preparation |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2858556A1 FR2858556A1 (fr) | 2005-02-11 |
FR2858556B1 true FR2858556B1 (fr) | 2006-03-10 |
Family
ID=34073131
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR0350403A Expired - Fee Related FR2858556B1 (fr) | 2003-08-06 | 2003-08-06 | Composition pharmaceutique solide dispersible et/ou orodispersible non pelliculee contenant au moins le principe actif metformine, et procede de preparation |
Country Status (7)
Country | Link |
---|---|
US (1) | US20070218129A1 (fr) |
EP (1) | EP1653936A2 (fr) |
JP (1) | JP2007501205A (fr) |
AU (1) | AU2004262964A1 (fr) |
CA (1) | CA2535026A1 (fr) |
FR (1) | FR2858556B1 (fr) |
WO (1) | WO2005013957A2 (fr) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1814528A2 (fr) * | 2004-10-08 | 2007-08-08 | Rubicon Research Private Limited | Procede pour fabriquer des compositions fortement compressible a delivrance controllee de metformine |
SI1878426T1 (sl) * | 2005-04-26 | 2010-09-30 | Dainippon Sumitomo Pharma Co | Granulatni pripravek ki vsebuje bigvanidno spojino |
WO2006122021A1 (fr) * | 2005-05-10 | 2006-11-16 | Novartis Ag | Procede d'extrusion permettant de fabriquer des compositions renfermant des composes therapeutiques peu compressibles |
JP5165582B2 (ja) * | 2005-12-16 | 2013-03-21 | メルク・シャープ・エンド・ドーム・コーポレイション | ジペプチジルペプチダーゼ−4インヒビターとメトホルミンとを組み合わせた医薬組成物 |
FR2898492B1 (fr) * | 2006-03-15 | 2008-06-06 | Pierre Fabre Medicament Sa | Comprimes orodispersibles de domperidone |
US20080107787A1 (en) * | 2006-11-02 | 2008-05-08 | The Coca-Cola Company | Anti-Diabetic Composition with High-Potency Sweetener |
WO2011154975A2 (fr) * | 2010-06-08 | 2011-12-15 | Cadila Healthcare Limited | Compositions pharmaceutiques de metformine |
WO2013077825A1 (fr) | 2011-11-23 | 2013-05-30 | Mahmut Bilgic | Procédé de fabrication d'une préparation comprenant de la metformine |
US9339489B2 (en) | 2013-03-15 | 2016-05-17 | Aprecia Pharmaceuticals Company | Rapid disperse dosage form containing levetiracetam |
WO2014144512A1 (fr) | 2013-03-15 | 2014-09-18 | Aprecia Pharmaceuticals Company | Forme pharmaceutique à dispersion rapide contenant du lévétiracétam |
JP6466399B2 (ja) | 2013-03-15 | 2019-02-06 | アプレシア・ファーマスーティカルズ・カンパニー | トピラマートの急速分散性の剤形 |
WO2014143935A1 (fr) | 2013-03-15 | 2014-09-18 | Aprecia Pharmaceuticals Company | Forme posologique d'oxcarbazépine à dispersion rapide |
WO2015071859A1 (fr) * | 2013-11-18 | 2015-05-21 | Ranbaxy Laboratories Limited | Composition dispersible orale d'un inhibiteur de dpp-iv |
EP3248594A1 (fr) | 2016-05-25 | 2017-11-29 | ratiopharm GmbH | Comprimé pour multiples applications orales |
CN108272762B (zh) * | 2018-03-15 | 2020-01-14 | 西南大学 | 香椿老叶总黄酮分散片及其制备方法 |
CA3183295A1 (fr) | 2020-06-26 | 2021-12-30 | Jaedeok Yoo | Comprimes rapidement orodispersibles a cavite interieure |
Family Cites Families (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1216486B (de) * | 1964-04-23 | 1966-05-12 | Merck Ag E | Verfahren zur Herstellung von Dragees |
JPS5438167B2 (fr) * | 1974-04-27 | 1979-11-19 | ||
US6288095B1 (en) * | 1987-09-04 | 2001-09-11 | Beecham Group P.L.C. | Compounds |
DE3856378T2 (de) * | 1987-09-04 | 2000-05-11 | Beecham Group Plc | Substituierte Thiazolidindionderivate |
US5130333A (en) * | 1990-10-19 | 1992-07-14 | E. R. Squibb & Sons, Inc. | Method for treating type II diabetes employing a cholesterol lowering drug |
GB9109862D0 (en) * | 1991-05-08 | 1991-07-03 | Beecham Lab Sa | Pharmaceutical formulations |
US5370878A (en) * | 1993-09-30 | 1994-12-06 | Hallmark Pharmaceuticals, Inc. | Method for preparing a direct compression granulated acetaminophen composition |
AR017512A1 (es) * | 1997-08-22 | 2001-09-12 | Smithkline Beecham Corp | Tabletas de metilcelulosa rapidamente desintegrables para administracion por via oral y procedimiento para prepararlas |
JP4278863B2 (ja) * | 1997-12-08 | 2009-06-17 | ブリストル−マイヤーズ スクイブ カンパニー | メトホルミンの新規塩および方法 |
KR100775154B1 (ko) * | 1997-12-19 | 2007-11-12 | 스미스클라인 비참 코포레이션 | 바이트-분산성 정제의 제조 방법 |
FR2774591B1 (fr) * | 1998-02-12 | 2000-05-05 | Lipha | Composition pharmaceutique comprenant l'association metformine et fibrate et son utilisation pour la preparation de medicaments destines a reduire l'hyperglycemie |
US6100300A (en) * | 1998-04-28 | 2000-08-08 | Bristol-Myers Squibb Company | Metformin formulations and method for treating intermittent claudication employing same |
JP4606582B2 (ja) * | 1998-04-29 | 2011-01-05 | 大日本住友製薬株式会社 | ビグアナイド系薬物の内服製剤 |
DK1736144T3 (en) * | 1998-05-18 | 2015-12-07 | Takeda Pharmaceutical | Orally disintegrating tablets. |
US6117451A (en) * | 1998-08-25 | 2000-09-12 | Pharmalogix, Inc. | Direct compression metformin hydrochloride tablets |
US6274608B1 (en) * | 1999-04-20 | 2001-08-14 | Novo Nordisk A/S | Compounds, their preparation and use |
MY125516A (en) * | 1999-11-16 | 2006-08-30 | Smithkline Beecham Plc | Novel composition based on thiazolidinedione and metformin and use |
US20030180352A1 (en) * | 1999-11-23 | 2003-09-25 | Patel Mahesh V. | Solid carriers for improved delivery of active ingredients in pharmaceutical compositions |
JP2003520226A (ja) * | 2000-01-21 | 2003-07-02 | ノバルティス アクチエンゲゼルシャフト | ジペプチジルペプチダーゼ−iv阻害剤および抗糖尿病薬剤を含む組合せ物 |
US6316029B1 (en) * | 2000-05-18 | 2001-11-13 | Flak Pharma International, Ltd. | Rapidly disintegrating solid oral dosage form |
US6358526B1 (en) * | 2000-08-16 | 2002-03-19 | Rexall Sundown | Method of making tablets and tablet compositions produced therefrom |
IN192750B (fr) * | 2000-12-15 | 2004-05-15 | Ranbaxy Lab Ltd | |
JP4848558B2 (ja) * | 2001-05-08 | 2011-12-28 | トーアエイヨー株式会社 | 塩酸メトホルミン含有速放性錠剤 |
US7183321B2 (en) * | 2001-12-17 | 2007-02-27 | Bristol-Myers Squibb Company | Antidiabetic formulation and method |
FR2834889B1 (fr) * | 2002-01-18 | 2004-04-02 | Roquette Freres | Forme pharmaceutique solide orodispersible |
WO2004017896A2 (fr) * | 2002-08-21 | 2004-03-04 | Merck & Co., Inc. | Traitement combine faisant intervenir un double agoniste de ppar alpha/gamma et un recepteur de type i d'angiotensine ii |
-
2003
- 2003-08-06 FR FR0350403A patent/FR2858556B1/fr not_active Expired - Fee Related
-
2004
- 2004-08-05 AU AU2004262964A patent/AU2004262964A1/en not_active Abandoned
- 2004-08-05 JP JP2006522382A patent/JP2007501205A/ja active Pending
- 2004-08-05 EP EP04786374A patent/EP1653936A2/fr not_active Withdrawn
- 2004-08-05 WO PCT/FR2004/050376 patent/WO2005013957A2/fr active Application Filing
- 2004-08-05 CA CA002535026A patent/CA2535026A1/fr not_active Abandoned
- 2004-08-05 US US10/567,345 patent/US20070218129A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
AU2004262964A1 (en) | 2005-02-17 |
CA2535026A1 (fr) | 2005-02-17 |
FR2858556A1 (fr) | 2005-02-11 |
EP1653936A2 (fr) | 2006-05-10 |
WO2005013957A2 (fr) | 2005-02-17 |
JP2007501205A (ja) | 2007-01-25 |
US20070218129A1 (en) | 2007-09-20 |
WO2005013957A3 (fr) | 2005-05-26 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PLFP | Fee payment |
Year of fee payment: 14 |
|
PLFP | Fee payment |
Year of fee payment: 15 |
|
PLFP | Fee payment |
Year of fee payment: 16 |
|
ST | Notification of lapse |
Effective date: 20200406 |