CO4700474A1 - Formulacion oral de 2-metil-tieno-benzodiacepina - Google Patents

Formulacion oral de 2-metil-tieno-benzodiacepina

Info

Publication number
CO4700474A1
CO4700474A1 CO96014566A CO96014566A CO4700474A1 CO 4700474 A1 CO4700474 A1 CO 4700474A1 CO 96014566 A CO96014566 A CO 96014566A CO 96014566 A CO96014566 A CO 96014566A CO 4700474 A1 CO4700474 A1 CO 4700474A1
Authority
CO
Colombia
Prior art keywords
oral formulation
cellulose
benzodiacepine
theno
methyl
Prior art date
Application number
CO96014566A
Other languages
English (en)
Inventor
George Randall Cochran
Tommy Clifford Morris
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23624847&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CO4700474(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of CO4700474A1 publication Critical patent/CO4700474A1/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806Coating materials
    • A61K9/2833Organic macromolecular compounds
    • A61K9/284Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
    • A61K9/2846Poly(meth)acrylates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806Coating materials
    • A61K9/2833Organic macromolecular compounds
    • A61K9/286Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2886Dragees; Coated pills or tablets, e.g. with film or compression coating having two or more different drug-free coatings; Tablets of the type inert core-drug layer-inactive layer
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

Abstract

Una formulación oral sólida que comprende olanzapina comoingrediente activo, mezclada íntimamente con un agente de carga; aglutinante, disgregante, un aglutinante seco para proporcionar friabilidad adecuada, y un lubricante; en la que dicha formulación oral sólida está recubierta con un polímero seleccionado entre el grupo formado por hidroxipropil hipromelosa, hidroxietil celulosa, metilhidroxietilcelulosa, carboxihipromelosa de sodio, hidroxipropil celulosa, polivinilpirrolidona, copolímero del éster dimetilaminoetílico metacrilato-éster dimetilaminoetílico metilacrilato, copolímero de etilacrilato-metilmetacrilato, hipromelosa y etilcelulosa.
CO96014566A 1995-03-24 1996-03-22 Formulacion oral de 2-metil-tieno-benzodiacepina CO4700474A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US41046595A 1995-03-24 1995-03-24

Publications (1)

Publication Number Publication Date
CO4700474A1 true CO4700474A1 (es) 1998-12-29

Family

ID=23624847

Family Applications (1)

Application Number Title Priority Date Filing Date
CO96014566A CO4700474A1 (es) 1995-03-24 1996-03-22 Formulacion oral de 2-metil-tieno-benzodiacepina

Country Status (46)

Country Link
US (4) US5919485A (es)
EP (2) EP1093815B1 (es)
JP (1) JPH11502848A (es)
KR (1) KR100408172B1 (es)
CN (1) CN1178662C (es)
AP (1) AP679A (es)
AR (2) AR001405A1 (es)
AT (3) ATE206924T1 (es)
AU (1) AU696601B2 (es)
BG (1) BG62594B1 (es)
BR (1) BR9607791A (es)
CA (1) CA2216372C (es)
CH (1) CH691217A5 (es)
CO (1) CO4700474A1 (es)
CR (1) CR5278A (es)
CZ (1) CZ296007B6 (es)
DE (3) DE19681287T1 (es)
DK (3) DK1093815T3 (es)
EA (1) EA000938B1 (es)
EE (1) EE03551B1 (es)
EG (1) EG24077A (es)
ES (2) ES2232379T3 (es)
FI (1) FI973749A (es)
GB (1) GB2313783B (es)
HU (1) HU225269B1 (es)
IL (1) IL117611A (es)
IS (1) IS1903B (es)
LT (1) LT4350B (es)
LU (1) LU90115B1 (es)
LV (1) LV11983B (es)
MY (1) MY113440A (es)
NO (1) NO320388B1 (es)
NZ (1) NZ306111A (es)
OA (1) OA10511A (es)
PE (1) PE44997A1 (es)
PL (1) PL188316B1 (es)
PT (2) PT1093815E (es)
RO (1) RO118370B1 (es)
SE (1) SE9703206D0 (es)
SI (3) SI9620041A (es)
SK (1) SK283745B6 (es)
TR (1) TR199701018T1 (es)
TW (1) TW426526B (es)
UA (1) UA44766C2 (es)
WO (1) WO1996029995A1 (es)
ZA (1) ZA962338B (es)

Families Citing this family (63)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CR5278A (es) * 1995-03-24 1996-07-04 Lilly Co Eli Formulacion oral de 2-metil-tieno-benzodiacepina
ID21762A (id) * 1996-09-24 1999-07-22 Lilly Co Eli Formulasi partikel bersaput
US20020035071A1 (en) * 1997-07-08 2002-03-21 Josef Pitha Mimicking the metabolic effects of caloric restriction by administration of glucose antimetabolites
US8563522B2 (en) * 1997-07-08 2013-10-22 The Iams Company Method of maintaining and/or attenuating a decline in quality of life
US20060116330A1 (en) * 1997-07-08 2006-06-01 The Iams Company Methods of mimicking the metabolic effects of caloric restriction by administration of mannoheptulose
US6617321B2 (en) 1997-09-30 2003-09-09 Eli Lilly And Company 2-methyl-thieno-benzodiazepine formulation
AU779452B2 (en) * 1999-12-28 2005-01-27 Cipla Limited New polymorphic forms of olanzapine
US7022698B2 (en) 1999-12-28 2006-04-04 U & I Pharmaceuticals, Ltd. Pharmaceutical compositions containing new polymorphic forms of olanzapine and uses thereof
US6348458B1 (en) 1999-12-28 2002-02-19 U & I Pharmaceuticals Ltd. Polymorphic forms of olanzapine
US6740753B2 (en) 2001-01-04 2004-05-25 Geneva Pharmaceuticals, Inc. Olanzapine crystal modification
US20030072731A1 (en) * 2001-05-15 2003-04-17 Cynthia Gulian Dip coating compositions containing starch or dextrin
US20030072729A1 (en) * 2001-05-15 2003-04-17 Christopher Szymczak Simethicone as weight gain enhancer
US20030070584A1 (en) 2001-05-15 2003-04-17 Cynthia Gulian Dip coating compositions containing cellulose ethers
US8309118B2 (en) 2001-09-28 2012-11-13 Mcneil-Ppc, Inc. Film forming compositions containing sucralose
GB0203061D0 (en) * 2002-02-08 2002-03-27 Novartis Ag Organic compounds
EP2316468A1 (en) 2002-02-22 2011-05-04 Shire LLC Delivery system and methods for protecting and administering dextroamphetamine
AU2002255196A1 (en) * 2002-04-18 2003-10-27 Dr. Reddy's Laboratories Ltd. Rapidly dispersing solid oral compositions
AU2003237305A1 (en) 2002-05-31 2003-12-19 Geneva Pharmaceuticals, Inc. Process of preparation of olanzapine form i
SI21270A (sl) * 2002-07-15 2004-02-29 Krka, Tovarna Zdravil, D.D., Novo Mesto Kristalne oblike olanzapina in postopki za njihovo pripravo
US7029112B2 (en) * 2002-08-05 2006-04-18 Mars, Incorporated Ink-jet printing on surface modified edibles and products made
US8168170B2 (en) * 2002-10-03 2012-05-01 The Procter And Gamble Company Compositions having an inner core and at least three surrounding layers
PL202856B1 (pl) * 2002-12-20 2009-07-31 Adamed Spo & Lstrok Ka Z Ogran Sposób otrzymywania farmaceutycznie czystej polimorficznej postaci I olanzapiny
WO2005009407A2 (en) * 2003-07-29 2005-02-03 Ranbaxy Laboratories Limited Oral pharmaceutical formulations of olanzapine
WO2005034921A1 (en) * 2003-10-07 2005-04-21 Andrx Pharmaceuticals Llc Rapidly disintegrating formulation
CA2546200A1 (en) * 2003-11-18 2005-06-02 3M Innovative Properties Company Olanzapine containing transdermal drug delivery compositions
US7785635B1 (en) 2003-12-19 2010-08-31 The Procter & Gamble Company Methods of use of probiotic lactobacilli for companion animals
US8877178B2 (en) 2003-12-19 2014-11-04 The Iams Company Methods of use of probiotic bifidobacteria for companion animals
US20050152884A1 (en) * 2003-12-19 2005-07-14 The Procter & Gamble Company Canine probiotic Bifidobacteria globosum
US20050158294A1 (en) * 2003-12-19 2005-07-21 The Procter & Gamble Company Canine probiotic Bifidobacteria pseudolongum
US8894991B2 (en) * 2003-12-19 2014-11-25 The Iams Company Canine probiotic Lactobacilli
ES2253091B1 (es) * 2004-07-27 2007-02-01 Inke, S.A. Solvato mixto de olanzapina, procedimiento para su obtencion y procedimiento de obtencion de la forma i de olanzapina a partir del mismo.
EP1838716B1 (en) 2005-01-05 2011-06-01 Eli Lilly And Company Olanzapine pamoate dihydrate
TWI320783B (en) 2005-04-14 2010-02-21 Otsuka Pharma Co Ltd Heterocyclic compound
JP2008536922A (ja) * 2005-04-22 2008-09-11 テバ・ファーマシューティカルズ・ユーエスエー・インコーポレイテッド オランザピンの医薬用経口崩壊錠
WO2006130187A1 (en) * 2005-05-31 2006-12-07 The Iams Company Feline probiotic lactobacilli
BRPI0611492B1 (pt) * 2005-05-31 2021-10-13 Mars, Incorporated Bifidobactéria probiótica felina
US20070014847A1 (en) * 2005-07-05 2007-01-18 Ahmed Salah U Coated capsules and methods of making and using the same
WO2007014124A2 (en) * 2005-07-22 2007-02-01 Myriad Genetics, Inc. High drug load formulations and dosage forms
WO2007049304A2 (en) * 2005-10-27 2007-05-03 Jubilant Organosys Limited Stable coated pharmaceutical formulation of olanzapine and process for preparing the same
GB0522473D0 (en) * 2005-11-03 2005-12-14 Actavis Group A pharmaceutical formulation
GB0522474D0 (en) 2005-11-03 2005-12-14 Actavis Group A pharmaceutical formulation
ES2279715B1 (es) * 2005-12-26 2008-06-01 Laboratorios Lesvi, S.L. Formulacion oral de olanzapina.
US7834176B2 (en) 2006-01-26 2010-11-16 Sandoz Ag Polymorph E of Olanzapine and preparation of anhydrous non-solvated crystalline polymorphic Form I of 2-methyl-4(4-methyl-1-piperazinyl)-10H-thieno[2,3-b][1,5] benzodiazepine (Olanzapine Form I) from the polymorphic Olanzapine Form E
US20070293479A1 (en) * 2006-05-18 2007-12-20 Osinga Niels J Olanzapine pharmaceutical composition
EP2043612B1 (en) * 2006-07-05 2010-04-28 Bilim Ilac Sanayii Ve Ticaret A.S. A stable olanzapine formulation with antioxidants
CL2007002807A1 (es) * 2006-09-29 2008-04-11 Synthon Bv Composicion farmaceutica en estado solido que comprende olanzapina o una sal farmaceuticamente aceptable de la misma y lactosa anhidra; tableta farmaceutica oral; procedimiento de preparacion de dicha tableta, util en el tratamiento de la esquizofren
CN101711158A (zh) 2007-02-01 2010-05-19 爱默思公司 使用葡萄糖抗代谢物、鳄梨或鳄梨提取物减轻哺乳动物炎症和应激反应的方法
JP4656672B2 (ja) * 2008-01-31 2011-03-23 杏林製薬株式会社 イミダフェナシンを有効成分とする口腔内速崩錠の製造方法
US9771199B2 (en) 2008-07-07 2017-09-26 Mars, Incorporated Probiotic supplement, process for making, and packaging
KR20120093060A (ko) * 2009-03-25 2012-08-22 카이틴, 아이엔씨. 초음파 냉각 시스템
US20110048048A1 (en) * 2009-03-25 2011-03-03 Thomas Gielda Personal Cooling System
US8505322B2 (en) * 2009-03-25 2013-08-13 Pax Scientific, Inc. Battery cooling
US20110051549A1 (en) * 2009-07-25 2011-03-03 Kristian Debus Nucleation Ring for a Central Insert
US10104903B2 (en) 2009-07-31 2018-10-23 Mars, Incorporated Animal food and its appearance
US8365540B2 (en) * 2009-09-04 2013-02-05 Pax Scientific, Inc. System and method for heat transfer
WO2012153347A2 (en) 2011-05-04 2012-11-15 Zentiva K.S. Oral pharmaceutical composition of olanzapine form 1
EP2919788A4 (en) 2012-11-14 2016-05-25 Univ Johns Hopkins METHODS AND COMPOSITIONS FOR THE TREATMENT OF SCHIZOPHRENIA
US9517212B1 (en) * 2012-11-15 2016-12-13 Chandra Zaveri Medicated adhesive pad arrangement
CN103919782B (zh) * 2013-01-15 2016-12-28 天津药物研究院有限公司 一种含有奥氮平的药物组合物及其制备方法
DK3043778T3 (da) * 2013-09-13 2017-11-27 Bayer Pharma AG Farmaceutiske sammensætninger, der indeholder refametinib
CN107007559B (zh) * 2017-04-21 2020-05-15 浙江京新药业股份有限公司 一种稳定的口服药物组合物及其制备方法
AU2018275686B2 (en) * 2017-06-02 2024-02-01 Xeris Pharmaceuticals, Inc. Precipitation resistant small molecule drug formulations
CN113143878A (zh) * 2021-03-19 2021-07-23 杭州新诺华医药有限公司 奥氮平组合物及其制备方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4172831A (en) * 1974-11-26 1979-10-30 Lilly Industries Limited Thieno-benzodiazepines
US4115568A (en) * 1974-11-26 1978-09-19 Lilly Industries Limited Thieno[3,2-b]-[1,5]benzodiazepines
GB2189698A (en) 1986-04-30 1987-11-04 Haessle Ab Coated omeprazole tablets
US4820522A (en) * 1987-07-27 1989-04-11 Mcneilab, Inc. Oral sustained release acetaminophen formulation and process
US5229382A (en) * 1990-04-25 1993-07-20 Lilly Industries Limited 2-methyl-thieno-benzodiazepine
GB9009229D0 (en) * 1990-04-25 1990-06-20 Lilly Industries Ltd Pharmaceutical compounds
ZA922776B (en) * 1991-04-29 1993-10-15 Lilly Co Eli Pharmaceutical compounds
JPH05194225A (ja) * 1991-11-07 1993-08-03 Yoshitomi Pharmaceut Ind Ltd 安定化された抗潰瘍剤含有製剤
PT582368E (pt) * 1992-05-29 2001-05-31 Lilly Co Eli Derivados de tienobenzodiazepina para o tratamento de doencas de cns
SE9302395D0 (sv) * 1993-07-09 1993-07-09 Ab Astra New pharmaceutical formulation
US5457101A (en) * 1994-06-03 1995-10-10 Eli Lilly And Company Thieno[1,5]benzoidiazepine use
CR5278A (es) * 1995-03-24 1996-07-04 Lilly Co Eli Formulacion oral de 2-metil-tieno-benzodiacepina
US5696115A (en) * 1995-04-21 1997-12-09 Eli Lilly And Company Method for treating nicotine withdrawal

Also Published As

Publication number Publication date
RO118370B1 (ro) 2003-05-30
MX9707186A (es) 1997-11-29
CN1179102A (zh) 1998-04-15
AP9701064A0 (en) 1997-10-31
SE9703206L (sv) 1997-09-05
US6780433B2 (en) 2004-08-24
ZA962338B (en) 1997-09-22
CA2216372C (en) 2007-11-20
NO974363D0 (no) 1997-09-22
IS1903B (is) 2003-11-20
PL188316B1 (pl) 2005-01-31
LV11983A (lv) 1998-03-20
US20010018071A1 (en) 2001-08-30
TW426526B (en) 2001-03-21
MY113440A (en) 2002-02-28
LV11983B (en) 1998-07-20
DE69615887D1 (de) 2001-11-22
CR5278A (es) 1996-07-04
CA2216372A1 (en) 1996-10-03
PT1093815E (pt) 2005-03-31
NO320388B1 (no) 2005-11-28
JPH11502848A (ja) 1999-03-09
UA44766C2 (uk) 2002-03-15
TR199701018T1 (xx) 1998-01-21
GB2313783A (en) 1997-12-10
DK109097A (da) 1997-11-12
HUP9800410A3 (en) 2000-01-28
DE69634053D1 (de) 2005-01-20
CN1178662C (zh) 2004-12-08
NZ306111A (en) 1999-02-25
ATA902296A (de) 1999-02-15
US7229643B2 (en) 2007-06-12
EA199700260A1 (ru) 1998-02-26
DE69634053T2 (de) 2005-12-22
OA10511A (en) 2002-04-24
FI973749A0 (fi) 1997-09-22
GB2313783B (en) 1998-11-18
PE44997A1 (es) 1997-10-23
DK173323B1 (da) 2000-07-24
IL117611A (en) 2002-05-23
EP1093815B1 (en) 2004-12-15
DK1093815T3 (da) 2005-04-25
SE9703206D0 (sv) 1997-09-05
KR100408172B1 (ko) 2004-02-18
SK283745B6 (sk) 2003-12-02
BG101901A (en) 1998-10-30
HU225269B1 (en) 2006-08-28
IS4565A (is) 1997-09-22
CH691217A5 (de) 2001-05-31
SI0733367T1 (en) 2002-06-30
DK0733367T3 (da) 2001-11-26
ES2232379T3 (es) 2005-06-01
NO974363L (no) 1997-11-17
US5919485A (en) 1999-07-06
US20050085462A1 (en) 2005-04-21
SI9620041A (sl) 1998-06-30
ATE284695T1 (de) 2005-01-15
EP0733367A1 (en) 1996-09-25
EG24077A (en) 2008-05-11
KR19980703189A (ko) 1998-10-15
DE19681287T1 (de) 1998-03-19
LT97149A (en) 1998-01-26
EA000938B1 (ru) 2000-06-26
LT4350B (lt) 1998-05-25
ATE206924T1 (de) 2001-11-15
AP679A (en) 1998-09-28
PT733367E (pt) 2002-03-28
ES2164837T3 (es) 2002-03-01
GB9719817D0 (en) 1997-11-19
SI1093815T1 (en) 2005-06-30
BR9607791A (pt) 1998-07-07
AR002720A1 (es) 1998-04-29
AU5428096A (en) 1996-10-16
US6190698B1 (en) 2001-02-20
EP0733367B1 (en) 2001-10-17
CZ296007B6 (cs) 2005-12-14
FI973749A (fi) 1997-09-22
EE9700328A (et) 1998-06-15
LU90115B1 (fr) 1997-09-10
AR001405A1 (es) 1997-10-22
CZ300197A3 (en) 1997-12-17
EE03551B1 (et) 2001-12-17
HUP9800410A2 (hu) 1998-07-28
PL322579A1 (en) 1998-02-02
SK128297A3 (en) 1998-03-04
BG62594B1 (bg) 2000-03-31
IL117611A0 (en) 1996-07-23
WO1996029995A1 (en) 1996-10-03
EP1093815A1 (en) 2001-04-25
AU696601B2 (en) 1998-09-17
DE69615887T2 (de) 2002-04-11
AT405606B (de) 1999-10-25

Similar Documents

Publication Publication Date Title
CO4700474A1 (es) Formulacion oral de 2-metil-tieno-benzodiacepina
US6509037B2 (en) Sustained release pharmaceutical matrix tablet of pharmaceutically acceptable salts of diclofenac and process for preparation thereof
FI962111A0 (fi) Mikrokapseloidut 3-piperidinyyli-substituoidut 1,2-bentsisoksatsolit ja 1,2-bentsisotiatsolit
KR950007841A (ko) 트라마돌 염을 함유하는 서방성 약물 제제
ES2094781T3 (es) Composicion farmaceutica de microparticulas con liberacion controlada y su proceso de preparacion.
ES8200557A1 (es) Un procedimiento para la preparacion de una composicion farmaceutica de cesion sostenida de un producto medio solido.
AR020610A1 (es) Utilizacion de un copolimero de acido metacrilico de tipo c segun la farmacopea us national formulary usp/nf, como agente de desagregacion y el procedimiento de fabricaion de un comprimido con dicho copolimero
BR0309004A (pt) Matriz para liberação gradual, invariante e independente dos compostos ativos
DK1276470T3 (da) Smagskaskerende overtrækssammensætning
AR016827A1 (es) PROCEDIMIENTO PARA LA PREPARACIoN DE UNA TABLETA FARMACÉUTICA
DE69636724D1 (de) Drei verschiedene polymertypen enthaltende formulierung mit verzögerter freigabe
BR0014549A (pt) Artigo elástico
AR036972A1 (es) Tableta bioadhesiva de hidratacion progresiva y liberacion sostenida y su uso en la fabricacion de un agente farmaceutico
DE69505949D1 (de) Arzneimittel, impfstoffe und hormone in polylaktidbeschichteten mikropartikel
KR920002135A (ko) 대장에서만 방출할수 있는 피복시킨 고체 약물형태
BR9708772A (pt) "comprimidos famacêuticos de liberação controlada que contém um veìculo à base de amilose reticulada e hidróxi propil metil celulose"
ATE391495T1 (de) Matrixsystem mit verzögerter freisetzung für hochlösliche wirkstoffe
UA94917C2 (ru) Композиции для местного применения
KR870000069A (ko) 안정한 고체 제형의 제조 방법
AR003928A1 (es) Comprimido del liberacion controlada
ES2111547T3 (es) Comprimido de liberacion prolongada.
EA200001201A3 (ru) Таблетка с основой, позволяющая осуществлять пролонгированное высвобождение триметазидина после введения оральным путем
ES2196620T3 (es) Formulacion de liberacion prolongada que contiene venlafaxina.
AU2697100A (en) Pharmaceutical capsule compositions containing loratadine and pseudoephedrine
ECSP961693A (es) Formulacion oral de 2- metil-tieno-benzodiaceptina