CN220438354U - Three-pad type detection test paper and detection kit thereof - Google Patents
Three-pad type detection test paper and detection kit thereof Download PDFInfo
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- CN220438354U CN220438354U CN202321843412.2U CN202321843412U CN220438354U CN 220438354 U CN220438354 U CN 220438354U CN 202321843412 U CN202321843412 U CN 202321843412U CN 220438354 U CN220438354 U CN 220438354U
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- 238000001514 detection method Methods 0.000 title claims abstract description 82
- 238000012360 testing method Methods 0.000 title claims abstract description 45
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 claims abstract description 35
- 239000010931 gold Substances 0.000 claims abstract description 26
- 229910052737 gold Inorganic materials 0.000 claims abstract description 26
- 239000007788 liquid Substances 0.000 claims abstract description 24
- 239000012528 membrane Substances 0.000 claims abstract description 11
- 238000010521 absorption reaction Methods 0.000 claims abstract description 8
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 8
- 238000003908 quality control method Methods 0.000 claims description 5
- 239000002390 adhesive tape Substances 0.000 claims description 4
- 241000463219 Epitheca Species 0.000 claims 3
- 239000013076 target substance Substances 0.000 abstract description 10
- 230000035945 sensitivity Effects 0.000 abstract description 8
- 230000002035 prolonged effect Effects 0.000 abstract description 3
- 230000009286 beneficial effect Effects 0.000 abstract description 2
- 239000000523 sample Substances 0.000 description 59
- 239000012535 impurity Substances 0.000 description 10
- 239000000126 substance Substances 0.000 description 7
- 238000012123 point-of-care testing Methods 0.000 description 5
- 238000013461 design Methods 0.000 description 4
- 238000000034 method Methods 0.000 description 3
- 238000004587 chromatography analysis Methods 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 230000002745 absorbent Effects 0.000 description 1
- 239000002250 absorbent Substances 0.000 description 1
- 239000003086 colorant Substances 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 239000003344 environmental pollutant Substances 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 230000036039 immunity Effects 0.000 description 1
- 230000003993 interaction Effects 0.000 description 1
- 230000002452 interceptive effect Effects 0.000 description 1
- 238000009533 lab test Methods 0.000 description 1
- 238000010339 medical test Methods 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012544 monitoring process Methods 0.000 description 1
- 230000035484 reaction time Effects 0.000 description 1
- 230000003014 reinforcing effect Effects 0.000 description 1
- 239000012488 sample solution Substances 0.000 description 1
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- Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
Abstract
The utility model provides a three pad type test paper and detection kit thereof, mainly includes bottom plate (1-1), sample pad one (1-2), gold mark pad (1-3), NC membrane (1-5) and water absorption pad (1-6), bottom plate (1-1) is located the bottom, its characterized in that, be equipped with sample pad two (1-4) between gold mark pad (1-3) and NC membrane (1-5), be equipped with sample pad one (1-2), gold mark pad (1-3), sample pad two (1-4), NC membrane (1-5) and water absorption pad (1-6) on bottom plate (1-1) in proper order, the length of sample pad one (1-2) is 10-15mm, the length of gold mark pad (1-3) is 10 + -2 mm, the length of sample pad two (1-4) is 3 + -2 mm. The utility model has the beneficial effects that the combination time of the gold mark and the target substance in the sample liquid is prolonged through the second sample pad (1-4), and the sensitivity of the product is improved.
Description
Technical Field
The utility model relates to the field of rapid detection, in particular to three-pad type detection test paper and a detection kit thereof.
Background
The detection card on the market at present adopts a combination mode of a sample pad and a gold mark pad, the detection card is a main product of POCT, and POCT is an abbreviation of Point-of-CareTesting (Point-of-CareTesting), and the detection card is also called on-site instant detection or bedside detection. It is a medical test method for immediate diagnosis and monitoring at the patient's site or clinical practice. POCT has a faster reaction time and a simpler operation procedure than conventional laboratory tests. The detection card sample pad has the function of removing impurities, and the gold-labeled pad contains gold-labeled substances which can be combined with target substances in the sample liquid. In addition, the detection card also comprises an NC film, and a test line (T line) and a quality control line (C line) are arranged on the NC film. When the sample liquid passes through the NC film, the gold-labeled substance can show different colors on the C line and the T line according to the combination degree of the gold-labeled substance and the target substance in the sample liquid. To achieve a normal chromatographic process, a bibulous paper is introduced to provide the proper suction.
However, although the above components are applied in the prior art, there are some limitations and disadvantages. When the sample is dripped on the sample pad, part of impurities are removed from the sample pad, the liquid is chromatographed upwards, and after the liquid is chromatographed on the gold-labeled pad, the gold-labeled substance on the pad is chromatographed upwards on the NC film together with the sample liquid. In this case, the gold-labeled substance does not have enough time to sufficiently bind to the target substance in the sample solution, and the target substance is chromatographed to the T-line junction on the NC membrane, resulting in a situation where sensitivity is limited.
Only a single sample pad was used in prior art designs for impurity removal. Although the sample pad has some degree of impurity removal, the need for interference immunity, if any, is not considered. In practice, various interfering substances may be present in the sample fluid, such as other non-target substances or environmental pollutants. Because the existing design only depends on a single sample pad to remove impurities, the anti-interference capability of the existing design has defects, and the target substances and the interference substances are difficult to effectively distinguish.
Disclosure of Invention
In order to improve the performance and sensitivity of the test card, the application aims to provide a three-pad test paper which is used for overcoming the limitations in the prior art and providing higher sensitivity and anti-interference capability. By introducing new structures and optimizing designs, the application enhances the accurate detection capability of target substances by improving the interaction between the sample pad and the gold-labeled pad.
In order to achieve the above purpose, the present utility model adopts the following technical scheme:
the three-pad type detection test paper mainly comprises a bottom plate 1-1, a first sample pad 1-2, a first gold mark pad 1-3, an NC film 1-5 and a water absorption pad 1-6, wherein the bottom plate 1-1 is arranged at the bottom.
Further, the NC film 1-5 mainly comprises an NC film main body 1-5-1, and a test line 1-5-2 and a quality control line 1-5-3 are respectively arranged in the middle of the NC film main body 1-5-1.
Further, the length of the first sample pad 1-2 is 15mm, the length of the gold mark pad 1-3 is 10mm, and the length of the second sample pad 1-4 is 5mm.
In order to achieve the purpose of the utility model, the utility model also provides a three-pad type detection kit which mainly comprises a detection test paper 1, a detection box upper shell 2 and a detection box lower shell 3, and is characterized in that the detection test paper 1 is the detection test paper in the first embodiment, the detection test paper 1 is positioned between the detection box upper shell 2 and the detection box lower shell 3, and the detection box upper shell 2 and the detection box lower shell 3 are mutually matched to form a hollow cuboid.
Further, the cartridge upper case 2 mainly includes an upper case main body 2-1, and a sample hole 2-3 for dropping a sample liquid and a detection hole 2-2 for displaying a detection result are provided on the upper case main body 2-1.
Further, the sample hole 2-3 is in a concave conical shape, and the detection hole 2-2 is in a concave long strip shape.
Further, the lower shell 3 of the detection box mainly comprises a lower shell main body 3-1, a supporting frame 3-2 for supporting the detection test paper 1 is arranged in the lower shell main body 3-1, and the supporting frame 3-2 and the detection test paper 1 are adhered together through a double faced adhesive tape 4.
The beneficial effects are as follows:
1. according to the utility model, the second sample pad 1-4 is arranged in the first gold mark pad 1-3 and the NC film 1-5, so that the combination time of the gold mark and a target substance in a sample liquid is prolonged through the second sample pad 1-4, and the sensitivity of a product is improved;
2. the anti-interference capability of the product is enhanced through the second sample pad 1-4;
3. the detection test paper 1 is arranged in the upper detection box shell 2 and the lower detection box shell 3, so that the sample liquid can be conveniently detected, and the sensitivity and the anti-interference capability of the product are improved.
Drawings
FIG. 1 is a schematic diagram of a three-pad test strip;
FIG. 2 is a perspective view of FIG. 1;
FIG. 3 is a schematic diagram of a three-pad type detection kit;
FIG. 4 is an exploded view of FIG. 3;
1: test paper, 2: detection box upper shell, 3: lower shell of detection box, 4: double faced adhesive tape, 1-1: bottom plate, 1-2: sample pad one, 1-3: gold mark pad, 1-4: sample pad two, 1-5: NC film, 1-6: absorbent pad, 2-1: upper case main body, 2-2: detection hole, 2-3: sample well, 3-1: lower shell main part, 3-2: support frame, 1-5-1: NC membrane body, 1-5-2: test line, 1-5-3: and a quality control line.
Detailed Description
Embodiment one:
as shown in FIG. 1-2, a three-pad test paper mainly comprises a bottom plate 1-1, a first sample pad 1-2, a gold mark pad 1-3, an NC film 1-5 and a water absorption pad 1-6, wherein the bottom plate 1-1 is positioned at the bottom of the three-pad test paper, a second sample pad 1-4 is arranged between the gold mark pad 1-3 and the NC film 1-5, the second sample pad 1-4 has the effect of performing secondary impurity removal, and after the two impurity removal, the sample liquid chromatographed on the NC film 1-5 is purer, so that the anti-interference capability of a product is enhanced.
The base plate 1-1 is sequentially provided with a first sample pad 1-2, a second gold mark pad 1-3, a second sample pad 1-4, an NC film 1-5 and a water absorption pad 1-6, wherein the first sample pad 1-2 is used for receiving sample liquid, and the sample liquid enters the first gold mark pad 1-3 after passing through the first sample pad 1-2 to drive the gold mark therein to move towards the water absorption pad 1-6. The gold mark pad 1-3 is coated with colloidal gold marked antibody; wherein the length of the first sample pad 1-2 is 10-15mm, the length of the gold mark pad 1-3 is 10+/-2 mm, and the length of the second sample pad 1-4 is 3+/-2 mm.
The NC film 1-5 mainly comprises an NC film main body 1-5-1, and a test line 1-5-2 and a quality control line 1-5-3 are respectively arranged in the middle of the NC film main body 1-5-1 and used for indicating the detection condition of a sample.
When the three-pad type detection test paper works, the principle of improving sensitivity is as follows: the sample liquid passes through the first sample pad 1-2 and then continues to be chromatographed upwards to drive the gold marks in the gold mark pad 1-3, and then passes through the second sample pad 1-4 to be chromatographed on the NC film 1-5, because the chromatography speed of the gold marks on the second sample pad 1-4 is low, the combination time of the gold marks and target substances in the sample liquid is prolonged, and the sensitivity of the product is improved;
principle of reinforcing anti-jamming capability: the sample liquid can play a role in removing impurities when the sample liquid is chromatographed on the first sample pad 1-2, and can play a role in removing impurities when the sample liquid is chromatographed on the second sample pad 1-4, and the sample liquid chromatographed on the NC film 1-5 is purer after the impurity is removed twice, so that the anti-interference capability of the product is enhanced.
Embodiment two:
as shown in fig. 3 and 4, a three-pad type detection kit mainly includes a detection test paper 1, a detection box upper case 2 and a detection box lower case 3, wherein the detection test paper 1 is the detection test paper in the first example, the detection test paper 1 is located between the detection box upper case 2 and the detection box lower case 3, and the detection box upper case 2 and the detection box lower case 3 are mutually matched to form a hollow cuboid.
The upper shell 2 of the detection box mainly comprises an upper shell main body 2-1, a sample hole 2-3 for dripping sample liquid and a detection hole 2-2 for displaying detection results are arranged on the upper shell main body 2-1, wherein the sample hole 2-3 is in a concave conical shape, and the detection hole 2-2 is in a concave long strip shape.
The lower shell 3 of the detection box mainly comprises a lower shell main body 3-1, a supporting frame 3-2 for supporting the detection test paper 1 is arranged in the lower shell main body 3-1, and the supporting frame 3-2 and the detection test paper 1 are bonded together through a double faced adhesive tape 4.
When the sample liquid is particularly used, the sample liquid drops are placed in the sample holes 2-3, the sample liquid enters the detection test paper 1, and the detection result on the detection test paper 1 can be seen through the detection holes 2-2 through chromatography.
The foregoing has shown and described the basic principles and main features of the present utility model and the advantages of the present utility model. It will be understood by those skilled in the art that the present utility model is not limited to the embodiments described above, and that the above embodiments and descriptions are merely illustrative of the principles of the present utility model, and various changes and modifications may be made without departing from the spirit and scope of the utility model, which is defined in the appended claims. The scope of the utility model is defined by the appended claims and equivalents thereof.
Claims (7)
1. The utility model provides a three pad type test paper, mainly includes bottom plate (1-1), sample pad one (1-2), gold mark pad (1-3), NC membrane (1-5) and water absorption pad (1-6), bottom plate (1-1) is located the bottom, its characterized in that, be equipped with sample pad two (1-4) between gold mark pad (1-3) and NC membrane (1-5), be equipped with sample pad one (1-2), gold mark pad (1-3), sample pad two (1-4), NC membrane (1-5) and water absorption pad (1-6) on bottom plate (1-1) in proper order, the length of sample pad one (1-2) is 10-15mm, the length of gold mark pad (1-3) is 10 + -2 mm, the length of sample pad two (1-4) is 3 + -2 mm.
2. The three-pad test strip according to claim 1, wherein the NC membrane (1-5) mainly comprises an NC membrane main body (1-5-1), and a test line (1-5-2) and a quality control line (1-5-3) are respectively provided in the middle of the NC membrane main body (1-5-1).
3. A test strip according to claim 1 or 2, wherein the sample pad one (1-2) has a length of 15mm, the gold-labelled pad (1-3) has a length of 10mm, and the sample pad two (1-4) has a length of 5mm.
4. The utility model provides a three pad type detection kit, mainly includes test paper (1), detection box epitheca (2) and detection box inferior valve (3), its characterized in that, test paper (1) is any one of claims 1-3 detection test paper, detection test paper (1) is located between detection box epitheca (2) and detection box inferior valve (3), and detection box epitheca (2) and detection box inferior valve (3) mutually support and form a hollow cuboid.
5. The three-pad type test kit according to claim 4, wherein the upper case (2) of the test kit mainly comprises an upper case main body (2-1), and a sample hole (2-3) for dropping a sample liquid and a test hole (2-2) for displaying a test result are provided on the upper case main body (2-1).
6. The three-pad type detection kit according to claim 5, wherein the sample hole (2-3) is in a concave conical shape, and the detection hole (2-2) is in a concave elongated shape.
7. The three-pad type detection kit according to claim 5 or 6, wherein the lower detection kit shell (3) mainly comprises a lower detection kit shell body (3-1), a supporting frame (3-2) for supporting the detection test paper (1) is arranged in the lower detection kit shell body (3-1), and the supporting frame (3-2) and the detection test paper (1) are adhered together through a double faced adhesive tape (4).
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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CN202321843412.2U CN220438354U (en) | 2023-07-13 | 2023-07-13 | Three-pad type detection test paper and detection kit thereof |
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CN202321843412.2U CN220438354U (en) | 2023-07-13 | 2023-07-13 | Three-pad type detection test paper and detection kit thereof |
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Publication Number | Publication Date |
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CN220438354U true CN220438354U (en) | 2024-02-02 |
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CN202321843412.2U Active CN220438354U (en) | 2023-07-13 | 2023-07-13 | Three-pad type detection test paper and detection kit thereof |
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2023
- 2023-07-13 CN CN202321843412.2U patent/CN220438354U/en active Active
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