CN212731144U - Chromatographic column capable of achieving accurate positioning - Google Patents

Chromatographic column capable of achieving accurate positioning Download PDF

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Publication number
CN212731144U
CN212731144U CN202021262745.2U CN202021262745U CN212731144U CN 212731144 U CN212731144 U CN 212731144U CN 202021262745 U CN202021262745 U CN 202021262745U CN 212731144 U CN212731144 U CN 212731144U
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China
Prior art keywords
wall
adjusting
column
driving
locking
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CN202021262745.2U
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Chinese (zh)
Inventor
龚行
刘余江
张海梦
张宝献
滕世超
张建璀
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Hualan Biological Engineering Co ltd
Hualan Gene Engineering Co ltd
HUALAN BIOLOGICAL ENGINEERING (CHONGQING) Inc
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Hualan Biological Engineering Co ltd
Hualan Gene Engineering Co ltd
HUALAN BIOLOGICAL ENGINEERING (CHONGQING) Inc
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Priority to CN202021262745.2U priority Critical patent/CN212731144U/en
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Abstract

The utility model discloses a chromatographic column with precise positioning, which comprises an outer barrel and a screw assembly, wherein one end of the outer barrel, which is far away from the screw assembly, is sealed, one end of the outer barrel, which is close to the screw assembly, is fixedly connected with a threaded sleeve and is arranged on an installation sleeve outside the screw assembly, the screw assembly comprises a compression bar with a limiting part at one end and a driving barrel arranged outside the compression bar in a sliding way, the limiting part is arranged in the outer barrel in a sliding way, the driving barrel is in threaded connection with the installation sleeve, and one end of the driving barrel is abutted against the limiting part; compared with the prior art, the utility model, pack not hard up the back and press once more in real time, through rotating the driving barrel, make it drive the depression bar through spacing portion and remove to the urceolus together, and spacing portion and depression bar can not rotate along with the driving barrel to pack in the urceolus and press through spacing portion once more through rotating the driving barrel in real time, pack can not produce in the inner tube and turn round power and take place the harm, consequently improved the effect and the life of chromatography post in the use.

Description

Chromatographic column capable of achieving accurate positioning
Technical Field
The utility model relates to a chromatography technical field, concretely relates to chromatographic column of accurate location.
Background
Chromatography is short for "chromatography"; the method is characterized in that a multi-component mixture is separated and measured by a chromatographic system by utilizing the difference of physical properties of each component.
A chromatographic column (as shown in figure 1) in the existing chromatographic system comprises a screw rod 1 and a transparent outer cylinder 2, one end of the outer cylinder 2 is sealed by a sealing plug 3, the other end of the outer cylinder 2 is fixedly connected with an installation sleeve 4, one end of the installation sleeve 4, which is far away from the outer cylinder 2, is rotatably clamped with a screwing sleeve 5, one end of the screw rod 1 sequentially passes through the screwing sleeve 5 and the installation sleeve 4 and then extends into the outer cylinder 2, the screw rod 1 is in threaded connection with both the screwing sleeve 5 and the installation sleeve 4, and one end of the screw rod 1, which is arranged in the outer cylinder 2, is connected; when the screw is used, the filler 19 is placed into the outer barrel 2, and the screwing sleeve 5 is rotated to enable the screw 1 to move into the outer barrel 2, so that the column head 6 compresses and fixes the filler 19.
When the chromatographic column is used, the column head 6 moves downwards to a preset height to press the filler 19 in the outer cylinder 2, and the support of the screwing sleeve 5 is just above the threads on the screw 1 and is not in the grooves of the threads. If the screwing sleeve 5 is continuously rotated to compact the packing 19, the packing 19 is pressed too tightly, so that the using effect of the chromatographic column is influenced; if the screwing sleeve 5 is not rotated continuously, when the pressure of the chromatographic system rises, the column head 6 is pushed to move upwards in the outer cylinder 2 until the abutting buckle of the screwing sleeve 5 is clamped in the groove of the thread, so that the filler 19 is loosened in the outer cylinder 2, and the use effect of the chromatographic column is influenced if the filler 19 is not compacted.
Because the screw 1 and the column head 6 are integrated, if the filler 19 is loosened and not compacted, the screwing sleeve 5 needs to be rotated to enable the screw 1 to drive the column head 6 to move downwards in the outer cylinder 2 to compact the filler 19, and when the screwing sleeve 5 is rotated, the screw 1 can drive the column head 6 to rotate together, the filler 19 can be driven to rotate together, the filler 19 is generally a gel product, the twisting force generated when the filler 19 rotates is easy to damage, and the using effect of the chromatographic column can be seriously influenced.
SUMMERY OF THE UTILITY MODEL
Not enough to exist among the prior art, the utility model aims to provide a chromatographic column of accurate location to solve prior art, pack in the urceolus not hard up back press once more in real time, pack the problem of being damaged and influence the result of use of chromatographic column easily.
In order to achieve the above purpose, the utility model adopts the following technical scheme: the utility model provides a chromatographic column of accurate location, includes that urceolus and one end arrange the screw rod subassembly in the urceolus in, the one end of keeping away from the screw rod subassembly of urceolus is sealed, and the urceolus is close to the one end fixedly connected with threaded sleeve of screw rod subassembly and establishes the installation cover in the screw rod subassembly outside, the screw rod subassembly includes that one end is equipped with the depression bar of spacing portion and slides the cover and establish the driving cylinder in the depression bar outside, and spacing portion slides and sets up in the urceolus, and the one end that driving cylinder and installation cover threaded connection just driven cylinder offsets.
Compared with the prior art, the utility model discloses following beneficial effect has:
the chromatographic column is formed by designing a screw rod assembly into a pressure rod, a driving cylinder sleeved outside the pressure rod in a sliding manner and a limiting part which is connected with the pressure rod and used for limiting the driving cylinder in a propping manner; pack not hard up back and press once more in real time, through rotating the driving barrel, make it drive the depression bar through spacing portion and remove to the urceolus together, and spacing portion and depression bar can not rotate along with the driving barrel to pack in the urceolus and press through spacing portion once more through rotatory driving barrel in real time, pack and can not produce in the inner tube and turn round power and take place the harm, consequently improved the effect and the life of chromatography column in the use.
Drawings
FIG. 1 is a prior art chromatography column configuration;
fig. 2 is a schematic structural diagram of an embodiment of the present invention;
FIG. 3 is a schematic structural view of the screw assembly of FIG. 2;
FIG. 4 is a cross-sectional view of the mounting sleeve of FIG. 2 taken along line A-A;
fig. 5 is a schematic view illustrating the connection between the latch and the driving post in fig. 4.
Detailed Description
The present invention will be described in further detail with reference to the following embodiments:
reference numerals in the drawings of the specification include: the device comprises a screw rod 1, an outer cylinder 2, a sealing plug 3, an installation sleeve 4, a screwing sleeve 5, a column head 6, a pressure rod 7, a driving cylinder 8, an annular protrusion 9, an annular groove 10, an adjusting hole 11, a pressing block 12, an adjusting column 13, a driving column 14, a clamping block 15, a locking block 16, a limiting block 17, an ejecting spring 18 and a filler 19.
As shown in fig. 2, the embodiment of the utility model provides a chromatography column of accurate location, including urceolus 2 and one end arrange the screw rod subassembly in urceolus 2 in, the one end of keeping away from the screw rod subassembly of urceolus 2 is sealed, and urceolus 2 is close to the one end fixedly connected with threaded sleeve of screw rod subassembly and establishes the installation cover 4 in the screw rod subassembly outside, as shown in fig. 3, the screw rod subassembly includes that one end is equipped with depression bar 7 and the slip cover of spacing portion and establishes the driving cylinder 8 in the depression bar 7 outside, and spacing portion slides and sets up in urceolus 2, and driving cylinder 8 offsets with the one end of 4 threaded connection of installation cover and driving cylinder 8 with spacing portion.
As shown in fig. 2 and fig. 3, according to another embodiment of the present invention, the chromatographic column with precise positioning further comprises a structure optimization for the limiting part, the limiting part is a column head 6 connected to one end of the compression rod 7, and the distance between the outer wall of the column head 6 and the central axis of the compression rod 7 is greater than the distance between the outer wall of the compression rod 7 and the central axis of the compression rod 7; the column head 6 is abutted against the driving cylinder 8 through the structural design of the column head 6, and when the driving cylinder 8 is rotated, the column head 6 drives the pressing rod 7 to move together towards the inner part of the outer cylinder 2, so that the column head 6 compacts and fixes the filler 19 in the outer cylinder 2.
And the length of the pressure lever 7 is designed to be larger than that of the driving cylinder 8, so that the pressure lever 7 penetrates through the driving cylinder 8, and the end part of the pressure lever 7 is convenient to take to move out of the outer cylinder 2 in the process of screwing the driving cylinder 8 out of the outer cylinder 2.
As shown in fig. 2 and fig. 3, according to another embodiment of the present invention, the chromatographic column with precise positioning further comprises a structure optimization for the driving cylinder 8, wherein an annular protrusion 9 is circumferentially connected to an outer wall of one end of the driving cylinder 8, which is far away from the column head 6, a rotating handle of the driving cylinder 8 is formed by the annular protrusion 9, so that a worker can hold the annular protrusion 9 to rotate the driving cylinder 8.
In order to avoid the hard contact between the driving cylinder 8 and the column head 6 and overlarge pressure, a rubber ring arranged between the column head 6 and the driving cylinder 8 is sleeved on the compression bar 7; the driving cylinder 8 is in soft contact with the column head 6 through a rubber ring, so that the safety performance is improved.
As shown in fig. 4, according to another embodiment of the present invention, in order to improve the firmness of the column cap 6 to compress the filler 19 in real time, the chromatographic column further comprises an adjustable locking mechanism connected to the driving cylinder 8 and disposed in the mounting sleeve 4, the inner wall of the mounting sleeve 4 is provided with an annular groove 10 along the circumferential direction thereof, the outer wall of the mounting sleeve 4 is provided with an adjusting hole 11 communicated with the annular groove 10, the adjustable locking mechanism comprises a pressing block 12 movably disposed in the annular groove 10 and an adjusting component slidably disposed in the adjusting hole 11, the power output end of the adjusting component is connected to the pressing block 12, and an adjustable locking component is disposed between the power input end of the adjusting component and the inner wall of the adjusting hole 11; and adjusting the locking state of the adjustable locking assembly, and controlling the abutting state of the pressing block 12 and the outer wall of the driving cylinder 8 through the adjusting assembly.
Specifically, the adjusting assembly comprises an adjusting column 13 connected with the pressing block 12 and a driving column 14 connected with one end, far away from the pressing block 12, of the adjusting column 13, and the adjustable locking assembly is connected between the driving column 14 and the inner wall of the adjusting hole 11.
The adopted adjustable locking assembly comprises two pairs of locking pieces connected to the inner wall of the adjusting hole 11 and two clamping blocks 15 (shown in figure 5) fixedly sleeved on the outer wall of the driving column 14, the two pairs of locking pieces are symmetrically arranged along the central line of the adjusting hole 11, each pair of locking pieces comprises two locking blocks 16 arranged at intervals along the length direction of the adjusting hole 11, and the intermittent length between the two locking blocks 16 is equal to the thickness of the clamping blocks 15; the two latch blocks 15 are symmetrically arranged on the driving column 14.
The adjusting column 13 is moved in the adjusting hole 11 through the driving column 14, and when the adjusting column 13 is moved in the adjusting hole 11 close to one side of the outer cylinder 2, the pressing block 12 moves towards the direction close to the outer cylinder 2; when the pressing plate abuts against the outer wall of the outer barrel 2, the fixture blocks 15 are located between the intermittences between the two locking blocks 16, when the driving post 14 is rotated through the connection mode of the adjusting post 13 and the driving post 14, the adjusting post 13 does not rotate along with the driving post 14 due to the pressing plate and the outer wall of the outer barrel 2, so that the two fixture blocks 15 are correspondingly screwed into the intermittences between the two locking blocks 16 in the two pairs of locking pieces one by one to fix the driving post 14, the locking state of the outer barrel 2 is fixed by the pressing block 12, and the firmness of the column head 6 in pressing the filler 19 is improved; the driving column 14 is rotated to enable the two clamping blocks 15 to move out from the interval between the two locking blocks 16 in the two pairs of locking pieces in a one-to-one correspondence manner, and then the adjusting column 13 drives the pressing block 12 to move towards the direction far away from the outer cylinder 2 by moving the driving column 14, so that the pressing block 12 is separated from the locking state of the outer cylinder 2, and the outer cylinder 2 can be rotated.
As shown in fig. 4, according to another embodiment of the present invention, in order to improve the control accuracy of the adjustable locking mechanism, the chromatographic column with precise positioning further includes an elastic reset assembly disposed between the adjusting column 13 and the inner wall of the adjusting hole 11, the elastic reset assembly is two elastic reset structures symmetrically disposed on the adjusting column 13, each of the two elastic reset structures includes a limiting groove disposed on the inner wall of the adjusting hole 11 along the length direction of the adjusting hole 11 and a limiting block 17 slidably disposed in the limiting groove and fixedly connected to the adjusting column 13, and an ejection spring 18 is connected between the limiting block 17 and the inner wall of the limiting groove; make the regulation post 13 drive briquetting 12 to the direction removal in-process that is close to urceolus 2 through drive post 14, when stopper 17 offsets with the inner wall that the spacing groove is close to drive barrel 8 one side, briquetting 12 offsets with the outer wall of drive barrel 8 this moment, and fixture block 15 is located between the intermittent type between two locking pieces 16, it then fixes drive post 14 with the intermittent type between two locking pieces 16 of two fixture block 15 one-to-one screw in two pairs of locking pieces to rotate drive post 14, the control accuracy is improved, the staff's of being convenient for fast operation.
As shown in fig. 4, according to another embodiment of the present invention, the chromatographic column with precise positioning further comprises an arc-shaped block matched with the outer wall of the driving cylinder 8 for optimizing the structure of the pressing block 12, so as to increase the contact area between the pressing block 12 and the driving cylinder 8, and further increase the stability of the driving cylinder 8 after the position is fixed; and the block diameter of the arc-shaped block is larger than the aperture of the adjusting hole 11, so that the pressing block 12 is prevented from moving out of the annular groove 10 to limit the pressing block 12 in the locking and fixing process of the pressing block 12 on the driving cylinder 8.
Finally, although the present invention has been described in detail with reference to the preferred embodiments, it should be understood by those skilled in the art that the present invention can be modified or replaced by other means without departing from the spirit and scope of the present invention, which should be construed as limited only by the appended claims.

Claims (9)

1. The utility model provides a chromatography column of accurate location, includes that urceolus and one end arrange the screw rod subassembly in the urceolus in, the one end of keeping away from the screw rod subassembly of urceolus is sealed, and the urceolus is close to the one end fixedly connected with threaded sleeve of screw rod subassembly and establishes the installation cover in the screw rod subassembly outside, a serial communication port, the screw rod subassembly includes that one end is equipped with the depression bar of spacing portion and slides the cover and establish the drive tube in the depression bar outside, and spacing portion slides and sets up in the urceolus, and the one end that drive tube and installation cover threaded connection just driven the.
2. A precisely positioned chromatography column according to claim 1, wherein: the limiting part is a column head connected with one end of the pressure rod, and the distance between the outer wall of the column head and the central shaft of the pressure rod is larger than the distance between the outer wall of the pressure rod and the central shaft of the pressure rod.
3. A precisely positioned chromatography column according to claim 1, wherein: the length of the pressing rod is greater than that of the driving barrel.
4. A precisely positioned chromatography column according to any one of claims 1-3, wherein: the outer wall of one end of the driving cylinder, which is far away from the column head, is circumferentially connected with an annular bulge.
5. A precisely positioned chromatography column according to any one of claims 1-3, wherein: the adjustable locking mechanism comprises a pressing block movably arranged in the annular groove and an adjusting component slidably arranged in the adjusting hole, the power output end of the adjusting component is connected with the pressing block, and the adjustable locking component is arranged between the power input end of the adjusting component and the inner wall of the adjusting hole; the locking state of the adjustable locking assembly is adjusted to control the pressing block to be in a state of abutting against the outer wall of the driving barrel through the adjusting assembly.
6. A precisely positioned chromatography column according to claim 5, wherein: the adjusting assembly comprises an adjusting column connected with the pressing block and a driving column connected with one end of the adjusting column far away from the pressing block, and the adjustable locking assembly is connected between the driving column and the inner wall of the adjusting hole.
7. A precisely positioned chromatography column according to claim 6, wherein: the adjustable locking assembly comprises two pairs of locking pieces connected to the inner wall of the adjusting hole and two clamping blocks fixedly sleeved on the outer wall of the driving column, the two pairs of locking pieces are symmetrically arranged along the central line of the adjusting hole, each pair of locking pieces comprises two locking blocks arranged at intervals along the length direction of the adjusting hole, and the intermittent length between the two locking blocks is equal to the thickness of the clamping blocks; the two clamping blocks are symmetrically arranged by the driving column, the two clamping blocks are screwed into the two locking blocks in the two pairs of locking pieces in a one-to-one correspondence mode and are fixed after the interval, and the pressing blocks are abutted to the outer wall of the driving cylinder.
8. A precisely positioned chromatography column according to claim 7, wherein: an elastic reset assembly is arranged between the adjusting column and the inner wall of the adjusting hole, the elastic reset assembly is two elastic reset structures symmetrically arranged by the adjusting column, the two elastic reset structures both comprise a limiting groove formed in the inner wall of the adjusting hole along the length direction of the adjusting hole and a limiting block which is arranged in the limiting groove in a sliding manner and is fixedly connected with the adjusting column, and an ejection spring is connected between the limiting block and the inner wall of the limiting groove; when the limiting block and the limiting groove are abutted against the inner wall of one side of the driving barrel, the pressing block is abutted against the outer wall of the driving barrel, and the clamping block is positioned between the two locking blocks.
9. A precisely positioned chromatography column according to claim 5, wherein: the briquetting is the arc piece with actuating cylinder outer wall assorted, and the block diameter of arc piece is greater than the aperture of adjusting the hole.
CN202021262745.2U 2020-06-30 2020-06-30 Chromatographic column capable of achieving accurate positioning Active CN212731144U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202021262745.2U CN212731144U (en) 2020-06-30 2020-06-30 Chromatographic column capable of achieving accurate positioning

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Application Number Priority Date Filing Date Title
CN202021262745.2U CN212731144U (en) 2020-06-30 2020-06-30 Chromatographic column capable of achieving accurate positioning

Publications (1)

Publication Number Publication Date
CN212731144U true CN212731144U (en) 2021-03-19

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116585752A (en) * 2023-07-18 2023-08-15 成都百泉生物医药科技有限公司 Chromatographic column and oscillating device for chromatographic column

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116585752A (en) * 2023-07-18 2023-08-15 成都百泉生物医药科技有限公司 Chromatographic column and oscillating device for chromatographic column
CN116585752B (en) * 2023-07-18 2023-10-20 成都百泉生物医药科技有限公司 Chromatographic column and oscillating device for chromatographic column

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