CN206294661U - A kind of Sterilized isolator for raising high-grade experimental animal - Google Patents
A kind of Sterilized isolator for raising high-grade experimental animal Download PDFInfo
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- CN206294661U CN206294661U CN201621217339.8U CN201621217339U CN206294661U CN 206294661 U CN206294661 U CN 206294661U CN 201621217339 U CN201621217339 U CN 201621217339U CN 206294661 U CN206294661 U CN 206294661U
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- cofferdam
- high efficiency
- efficiency particulate
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Abstract
The utility model discloses a kind of Sterilized isolator for raising high-grade experimental animal, including support and cofferdam；Place the raising frame of at least double-layer structure in cofferdam inside, the side that animal feeding box cofferdam is placed with raise frame every layer is provided with cylinder-shaped transfer chamber, the both sides of transfer chamber are sealed by interior cap and outer cap respectively, interior cap leads to the side of cofferdam positioned at transfer chamber, at least two spraying disinfections mouthful are provided with outer cap, each spraying disinfection is intraoral to be fitted with sealing-plug；The air inlet and air outlet of cofferdam both sides are connected to air intake high efficiency particulate air filter and air-out high efficiency particulate air filter, air-out high efficiency particulate air filter is two for being arranged in parallel, each air-out high efficiency particulate air filter is responsible for air-out by air-out branch pipe and is connected, and is provided with valve on two air-out branch pipes.The utility model sets two spraying disinfections mouthful, the pressure in balance transfer chamber, it is to avoid interior cap comes off；Used by the switching of two air-out high efficiency particulate air filters, reduce the contaminated chance of animal.
Description
Technical field
The utility model is related to the breeding apparatus for experimental animal, and high-grade experimental animal is raised more particularly, to one kind
Sterilized isolator.
Background technology
Isolator is to raise aseptic, the SPF grades of preferable place of experimental animal animal.And isolator has safety, warp in itself
The advantages of Ji, sterilizing are fully, space availability ratio is high.The high-level animal such as germfree animal, gnotobiotic animal must raise it is aseptic every
In device, and the quality of separator system facility, directly affect germfree animal, SPF grade of experimental animal animal and remain simple other
The length of time.
With the fast development of pharmaceuticals industry and life science, the demand of annual experimental animal is also constantly increasing
Plus, what usage amount was maximum among these is exactly laboratory rodent.Increasingly become more meticulous in medicine research and development and medical research, Quality Control
It is increasingly stricter, under the more and more perfect overall background of appraisement system, no-special pathogen (Specific pathogen free,
SPF) level laboratory rodent has turned into the master in the field such as medicine research and development, life science and medical research, institution of higher learning's teaching
Want experimental animal.SPF grades of experimental animal carries main latent infection or opportunistic in addition to the cause of disease that clean animal should be excluded, not
Big cause of disease is disturbed with to scientific research.Germfree animal can be even used in some required precisions experiment very high, i.e., not
The experimental animal of all life body can be detected.Carrying out scientific research using SPF grades of experimental animal and germfree animal can exclude certain
The influence of a little potential infectious disease, microorganism or serum antibodies to studying, so that experimental result is accurately and reliably.This is just dynamic to experiment
The feeding environment of thing proposes requirement very high, the environment for raising SPF grades of experimental animal or germfree animal must be it is controllable, can
Sterilization, reusable and natural environment is completely isolated, so as to ensure experimental animal not by the shadow of environmental change
Ring, do not polluted by external microbe.
Current Sterilized isolator in feeding process, in cofferdam needed for supplement during article, it is necessary to article is positioned over
Spraying disinfection is carried out in the transfer chamber of cofferdam side, and is kept for a period of time seal, but in the process sprayed to transfer chamber
In, its interior pressure gradually increases, and causes the seal cap on the inside of transfer chamber to there is the phenomenon for coming off；In addition, in the row to cofferdam
, it is necessary to suspend whole inflation system when wind high efficiency particulate air filter is cleared up, animal may be polluted.
Utility model content
For problems of the prior art, the utility model provide it is a kind of raise high-grade experimental animal it is aseptic every
From device, can be used to raise germfree animal, gnotobiotic animal and SPF grades of high-level animal etc., and it is contaminated animal can be greatly decreased
Chance.
The concrete technical scheme that the utility model is used is as follows：
A kind of Sterilized isolator for raising high-grade experimental animal, including support and the cofferdam being fixed in support；
Described cofferdam is transparent soft nacelle, and the raising frame of at least double-layer structure is placed in inside, raise frame every layer
Inside it is placed with animal feeding box；
The side of the cofferdam is provided with cylinder-shaped transfer chamber, and the both sides of the transfer chamber pass through interior cap and outer cap respectively
Sealing, wherein interior cap leads to the side of cofferdam positioned at transfer chamber, is provided with least two spraying disinfections mouthful on described outer cap,
And each spraying disinfection is intraoral is fitted with sealing-plug；
The air inlet and air outlet of the cofferdam both sides are connected to air intake high efficiency particulate air filter and air-out high efficiency filter
Device, wherein, air-out high efficiency particulate air filter is two for being arranged in parallel, and each air-out high efficiency particulate air filter is by air-out branch pipe and air-out master
Pipe is connected, and is provided with valve on two air-out branch pipes.
In the utility model, the material added to cofferdam will first be put into transfer chamber the treatment that carries out disinfection, due to transmission
At least two spraying disinfections mouthful are provided with the outer cap of room, when carrying out spraying disinfection by one of spraying disinfection mouthful, are kept
Another spraying disinfection mouthful is opened simultaneously, during thimerosal is full of transfer chamber, is balanced by this spraying disinfection mouthful
Pressure in transfer chamber, it is to avoid cause coming off for interior cap because spray causes pressure to increase.
Further, two air-out high efficiency particulate air filters of parallel connection, one of air-out high efficiency particulate air filter are set in air outlet
As standby, when needing to clear up the air-out high efficiency particulate air filter being currently in use, by Valve controlling air-out branch pipe, switching
It is standby air-out high efficiency particulate air filter, remains and the gas in cofferdam is changed.
Generally, support is double-layer structure, the cross bar that described support includes column and is connected between column, described horizontal stroke
Bar is that described cofferdam is placed between three layers for being sequentially arranged up and down, adjacent two layers cross bar, wherein, connect in the middle part of the column
The bracing piece parallel with cross bar is connected to, on the one hand for the structural strength of lifting bracket, it can also be used to which the installation of cofferdam is fixed.
Cofferdam remains expansion after inflation, is the position for more preferably fixing cofferdam in support, as preferred,
The top of the cofferdam is fixed after cross bar or bracing piece is bypassed at least provided with two cingulums, the cingulum by button.
Further, the junction of the cofferdam and cingulum sets flexible thickening layer, such as transparent rubber layer, layer of silica gel or modeling
The bed of material, it is to avoid cingulum tears in use, the normal of influence cofferdam is used.
Wherein, the bottom of the support is provided with the castor of brake, is easy to the displacement of support, possesses more preferable practicality
Property.
Stainless steel steel frame construction is usually due to raising frame, and cofferdam is generally PVC materials, to avoid raising the bottom of frame
Cofferdam is scratched in portion, it is further preferred that the foot for raising frame is arranged flexible protective jacket, plays protective separation cabin
Effect.
In the utility model, described spraying disinfection mouthful is two, you can the need for meeting air pressure balance, one of position
In the middle part of outer cap, another is near the edge of outer cap so that the sterilization spraying of injection is quickly full of whole transfer chamber, subtracts
The spilling of few thimerosal.
The utility model simple structure, it is easy to use；By setting two spraying disinfections mouthful, the pressure in balance transfer chamber
Power, it is to avoid cause coming off for interior cap because spray causes pressure to increase；Used by the switching of two air-out high efficiency particulate air filters,
Remain and the gas in cofferdam is changed, to reduce the contaminated chance of animal.
Brief description of the drawings
Fig. 1 is the front view of Sterilized isolator；
Fig. 2 is the rearview of Sterilized isolator；
Fig. 3 is the right side view of Sterilized isolator.
Specific embodiment
Sterilized isolator as shown in FIG. 1 to 3, including double-layer structure support 9 and be fixed in support 9 two every
From cabin 13.
Support 9 includes column 6 and the cross bar 11 being connected between column 6, and cross bar 11 is three layers for being sequentially arranged up and down, every
Between adjacent two layers cross bar 11 is placed on from cabin 13, in addition, the middle part of column 6 is connected with the bracing piece 12 parallel with cross bar 11, one
Aspect is used for the structural strength of lifting bracket, it can also be used to which the installation of cofferdam is fixed.
It is the position for more preferably fixing cofferdam 13 in support 9 in the present embodiment, the top of cofferdam 13 is provided with cingulum
14, the cingulum 14 is fixed after the cross bar 11 or bracing piece 12 for bypassing upper strata by button.Generally, the unilateral quantity of cingulum 14 is
3~5, can specifically be configured according to the size of cofferdam 13.In addition, cofferdam 13 is provided with bullet with the junction of cingulum 14
Property thickening layer 15, it is to avoid cingulum tears in use, the normal use of influence cofferdam.For ease of the displacement of support 9, bottom
Portion is provided with the castor 20 of brake.
In the present embodiment, cofferdam 13 is the transparent soft nacelle of PVC materials, and the raising frame 7 of three-decker is placed in inside, raises
Animal feeding box 10 is placed with support frame 7 every layer, and the side of each cofferdam 13 is provided with multiple operation gloves 21, it is right to be same as
The animal raised in frame 7 carries out operation treatment.The side of cofferdam 13 is provided with cylinder-shaped transfer chamber 1, the transfer chamber 1
Both sides are sealed by interior cap 8 and outer cap 4 respectively, wherein interior cap 8 is located at the side that cofferdam 13 is led in transfer chamber 1.Wherein, outer cap
Two spraying disinfections mouthful 5 are provided with 4, sealing-plug (not shown) is fitted with each each spraying disinfection mouthful 5, one of them
Positioned at the middle part of outer cap 4, another is near the edge of outer cap 4；Article to be sterilized is placed in transfer chamber 1, is extracted close
Blocking, when carrying out spraying disinfection by one of spraying disinfection mouthful 5, keeps another spraying disinfection mouthful 5 to open simultaneously, is disappearing
Venom prevents outer cap from coming off, after the completion of sterilization, you can will transmit full of the pressure balance inside during transfer chamber 1, keeping
In indoor item transfer to cofferdam 13.
The air inlet and air outlet of the both sides of each cofferdam 13 are connected to air intake high efficiency particulate air filter 3 and air-out high efficiency filter
Device 18, air intake high efficiency particulate air filter 3 is connected to air inlet main pipe 2, and ventilation makes to keep positive compression swelling, air-out high efficiency filter in cofferdam 13
Device 18 is two for being arranged in parallel, and each air-out high efficiency particulate air filter 18 is responsible for 19 and is connected by air-out branch pipe 17 and same air-out,
And it is provided with valve 16 on two air-out branch pipes 17.One of air-out high efficiency particulate air filter 18 is needing to align as standby
When the air-out high efficiency particulate air filter 18 for using is cleared up, air-out branch pipe 7 is controlled by valve 6, switch to standby air-out high
Effect filter, remains to the gas discharge in cofferdam, reduces the contaminated risk of animal.
Raising frame 7 in the present embodiment is stainless steel steel frame construction, to avoid the bottom for raising frame from scratching cofferdam 13,
The foot for raising frame 7 is arranged flexible protective jacket, plays a part of protective separation cabin.
Preferable implementation example of the present utility model is the foregoing is only, the utility model is not limited to, it is all in this reality
Within new spirit and principle, any modification, equivalent substitution and improvements made etc. should be included in guarantor of the present utility model
Within the scope of shield.
Claims (8)
1. a kind of Sterilized isolator for raising high-grade experimental animal, it is characterised in that：Including support and being fixed in support
Cofferdam；
Described cofferdam is transparent soft nacelle, and the raising frame of at least double-layer structure is placed in inside, is put in raise frame every layer
It is equipped with animal feeding box；
The side of the cofferdam is provided with cylinder-shaped transfer chamber, and the both sides of the transfer chamber are close by interior cap and outer cap respectively
Envelope, wherein interior cap leads to the side of cofferdam positioned at transfer chamber, is provided with least two spraying disinfections mouthful on described outer cap, and
Each spraying disinfection is intraoral to be fitted with sealing-plug；
The air inlet and air outlet of the cofferdam both sides are connected to air intake high efficiency particulate air filter and air-out high efficiency particulate air filter, its
In, air-out high efficiency particulate air filter is two for being arranged in parallel, and each air-out high efficiency particulate air filter is responsible for air-out by air-out branch pipe and connected
Connect, and valve is provided with two air-out branch pipes.
2. Sterilized isolator as claimed in claim 1, it is characterised in that：Described support include column and be connected to column it
Between cross bar, described cross bar is that described cofferdam is placed between three layers for being sequentially arranged up and down, adjacent two layers cross bar.
3. Sterilized isolator as claimed in claim 2, it is characterised in that：It is connected with the middle part of the column parallel with cross bar
Bracing piece.
4. Sterilized isolator as claimed in claim 3, it is characterised in that：The top of the cofferdam is at least provided with two buttons
Band, the cingulum is fixed after cross bar or bracing piece is bypassed by button.
5. Sterilized isolator as claimed in claim 4, it is characterised in that：The cofferdam is provided with bullet with the junction of cingulum
Property thickening layer.
6. the Sterilized isolator as described in claim any one of 1-5, it is characterised in that：The bottom of the support is provided with stopping
The castor of car.
7. the Sterilized isolator as described in claim any one of 1-5, it is characterised in that：The foot for raising frame is arranged with soft
The protective jacket of property.
8. the Sterilized isolator as described in claim any one of 1-5, it is characterised in that：Described spraying disinfection mouthful is two,
One of them is located at the middle part of outer cap, and another is near the edge of outer cap.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201621217339.8U CN206294661U (en) | 2016-11-10 | 2016-11-10 | A kind of Sterilized isolator for raising high-grade experimental animal |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201621217339.8U CN206294661U (en) | 2016-11-10 | 2016-11-10 | A kind of Sterilized isolator for raising high-grade experimental animal |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN206294661U true CN206294661U (en) | 2017-07-04 |
Family
ID=59202323
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201621217339.8U Active CN206294661U (en) | 2016-11-10 | 2016-11-10 | A kind of Sterilized isolator for raising high-grade experimental animal |
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| Country | Link |
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| CN (1) | CN206294661U (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107801638A (en) * | 2017-11-02 | 2018-03-16 | 深圳市前海金卓生物技术有限公司 | A kind of germfree animal carrier |
| CN110447547A (en) * | 2019-09-10 | 2019-11-15 | 赛业（苏州）生物科技有限公司 | Sterilized isolator |
| CN110663568A (en) * | 2019-11-07 | 2020-01-10 | 深圳市泓腾生物科技有限公司 | Sterile soft bag isolator |
| CN113207717A (en) * | 2021-05-26 | 2021-08-06 | 深圳净拓生物科技有限公司 | Aseptic isolator for experimental animals |
-
2016
- 2016-11-10 CN CN201621217339.8U patent/CN206294661U/en active Active
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107801638A (en) * | 2017-11-02 | 2018-03-16 | 深圳市前海金卓生物技术有限公司 | A kind of germfree animal carrier |
| CN110447547A (en) * | 2019-09-10 | 2019-11-15 | 赛业（苏州）生物科技有限公司 | Sterilized isolator |
| CN110663568A (en) * | 2019-11-07 | 2020-01-10 | 深圳市泓腾生物科技有限公司 | Sterile soft bag isolator |
| CN110663568B (en) * | 2019-11-07 | 2024-04-26 | 深圳市泓腾生物科技有限公司 | Sterile soft package isolator |
| CN113207717A (en) * | 2021-05-26 | 2021-08-06 | 深圳净拓生物科技有限公司 | Aseptic isolator for experimental animals |
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