CN205787345U - A kind of based on microscopical automatic detection system - Google Patents
A kind of based on microscopical automatic detection system Download PDFInfo
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- CN205787345U CN205787345U CN201620735059.XU CN201620735059U CN205787345U CN 205787345 U CN205787345 U CN 205787345U CN 201620735059 U CN201620735059 U CN 201620735059U CN 205787345 U CN205787345 U CN 205787345U
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- motor
- film magazine
- automatic detection
- detection system
- checking matter
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Abstract
This utility model relates to a kind of based on microscopical automatic detection system.Described system includes the mechanical system being arranged on base, optical microscope and for controlling the control system of the motor of mechanical system, also includes the CCD camera being arranged in optical microscope frame, and the computer being positioned at outside base.Checking matter smear is moved under optical microscope by mechanical system, the light that the light source of optical microscope sends passes checking matter smear, through object lens focal imaging on the electronic eyepiece of CCD camera, CCD camera is sent to computer and carries out image procossing and detection after the optical signalling of imaging is converted into the signal of telecommunication.This utility model achieves the fully-automated synthesis identification of checking matter, and automaticity is high, enormously simplify detection program, reduce the subjectivity because of manual detection and the error brought of lacking experience, improve detection speed and efficiency, reduce hand labor intensity, saved human resources.
Description
Technical field
This utility model relates to optical image technology, automatic control technology and computer image processing technology, is specifically related to
A kind of based on microscopical automatic detection system.
Background technology
Microscope the earliest is to manufacture in Holland latter stage in 16th century.Utility model person is Holland optician Ya Sizhan
Gloomy, make easy microscope with two panels lens, but do not do any important observation with these instruments.Had two later
Individual starts to use microscope in science.First is Italian scientist Galileo.He observes one by microscope
After insecticide, for the first time its compound eye is described.Second is Holland's flax businessman's Lie Wen Hooke, oneself association
Grind lens, and describe many naked eyes invisible microphyte of institute and animal for the first time.
At present, microscope have been widely used for social production, scientific research, detect, the various aspects such as teaching, the most raw
Thing medical domain.But the most microscopical operate with, and the storage of image information, process, printing etc. the most not very convenient,
Most microscopes can only be operated manually.In recent years, although in terms of microscopical automatization, had bigger progress, but
Microscopical automaticity is not the highest.
The Chinese invention patent of Publication No. CN1553241A, discloses a kind of automatic optical microscope, including one by
The main microscope that eyepiece, object lens, object stage, condenser lens, lighting source are constituted, described main microscope top is equipped with a figure
As smear camera, described object lens are provided with electrodynamic transducer, and described object stage is provided with horizontal cross shaft motor and horizontal longitudinal axis
Motor, the column of described main microscope is provided with vertical axes motor；Described horizontal cross shaft motor is by drive mechanism and one
Specimen holder locating rack drive connection, described horizontal longitudinal axis motor is by drive mechanism and described object stage drive connection, described perpendicular
D-axis motor is by drive mechanism and object stage drive connection；Also including a controller, this controller is by embedded Control electricity
Road, LCDs, horizontal cross shaft motor-drive circuit, horizontal longitudinal axis motor-drive circuit, vertical axes motor-drive circuit, water
The dynamic control command code device of translation, the most mobile control command code device, lamplight brightness control command code device, object lens conversion control
Command encoder processed, operation handle are constituted；Described controller circuitry is connected with upper control computer by communication interface circuit.
The advantage of this invention is that by automatically focusing on of image and automatically scans.Its shortcoming is that automaticity is the highest, it is impossible to realize
Automatically moving of checking matter slide glass, can not be converted into optical imagery the signal of telecommunication and send computer to automatically process and identify.
Utility model content
In order to solve the above-mentioned problems in the prior art, the utility model proposes a kind of based on microscopical automatically
Detecting system.
For reaching above-mentioned purpose, this utility model adopts the following technical scheme that
A kind of based on microscopical automatic detection system, including the mechanical system being arranged on base, optical microscope
With for controlling to provide the control system of the motor of power for mechanical system, also include being arranged in optical microscope frame
CCD camera, and the computer being positioned at outside base.Checking matter smear is moved under optical microscope by mechanical system, and optics shows
The light that the light source of micro mirror sends passes checking matter smear, through object lens focal imaging on the electronic eyepiece of CCD camera, CCD phase
Machine is sent to computer and carries out image procossing and detection after the optical signalling of imaging is converted into the signal of telecommunication.
Further, mechanical system includes being arranged on base the turnover storehouse for the mobile film magazine placing checking matter smear
Mechanism, pushing mechanism, elevator mechanism, be arranged on the object stage in optical microscope frame, Z axis guiding mechanism, turret.
Further, barn in-and-out machine structure includes passing in and out storehouse motor and storehouse is stepper motor driven is positioned at upper strata by passing in and out
Conveyer belt be positioned at the crank connecting link of lower floor, used for conveyer belt in mobile film magazine, crank connecting link for the film magazine that will detect from
Barn in-and-out machine structure is fetched.
Further, pushing mechanism includes push jack motor and push jack framework.The connecting plate of push jack framework is by pressure zone plate
Being connected on cog belt, push jack step motor drive cog belt does back and forth movement.Push jack framework is divided into upper and lower two-layer, and upper strata pushes away
Film magazine is shifted onto in the box torr of elevator mechanism by the push pedal of sheet framework by barn in-and-out machine structure, and completes checking matter smear and go out, enter film magazine
Operation；Film magazine is pushed back below elevator mechanism by the hook plate of lower floor's push jack framework.
Further, elevator mechanism includes elevator motor, screw pair, line slideway auxiliary and support thereof, elevator
Motor drives screw pair to drive the box torr placing film magazine to do vertical motion on line slideway auxiliary by cog belt.?
Support is provided with the side lay of film magazine, and side lay is by the pressing plate being arranged in fixed plate and with stage clip
Telescopic shaft coordinates, and unclamps film magazine from the side of two positions of film magazine vertical direction motion, and remaining position compresses film magazine.
Further, object stage is connected with the object stage supporting plate of optical microscope by pedestal.Object stage motor leads to
Screw pair of overdriving makes object stage carry out the motion of X, Y-direction on line slideway auxiliary, by checking matter smear from handing-over position
Put (checking matter smear moves to original position during object stage) to move to image space.Control system utilizes X, the grating of Y-axis is compiled
The Displacement Feedback signal of code device output carries out closed loop control to object stage motor, makes object stage full in the motion of X, Y-direction
The positioning accuracy request of foot imaging.
Further, Z axis guiding mechanism is for realizing the focusing of optical microscope, including fine-tuning mechanism and coarse adjustment mechanism,
Coarse adjustment mechanism is adjusted step motor drive cog belt by Z axis thus controls the lifting of object stage；Fine-tuning mechanism is directly connected to micro-
Mirror Z axis, control system utilizes the Displacement Feedback signal of the grating encoder output being arranged on Z axis to enter Z axis adjustment motor
Row closed loop control, makes the lifting of thing platform meet the required precision focused on.
Further, turret includes lens rotation mechanism and barcode scanner.Turret rotating mechanism is by thing
Mirror turntable step motor drive cog belt thus drive turret (by profile of tooth belt wheel) to rotate, control system utilize be arranged on
The grating encoder at turret motor rear portion, output displacement feedback signal carries out closed loop control to turret motor
System, it is achieved the conversion of the object lens of different multiples.Barcode scanner is for obtaining the barcode identification information on checking matter smear.
Further, mechanical system also includes the syringe pump mechanism being arranged on base, and syringe pump mechanism includes oil bottle, note
Penetrate pump and syringe pump motor；Syringe pump motor drives screw mandrel to drive syringe pump to move reciprocatingly by cog belt, will
Oil droplet, to the imaging region on checking matter smear, makes image clear.
Further, control system includes driver, controller, grating encoder and lead limit switch；Controller is defeated
The pulse signal gone out amplifies rear drive motor through driver and rotates；Controller utilizes the displacement signal that grating encoder feeds back
Motor is carried out closed loop control；Lead limit switch feedback limit position signalling controls letter to computer, computer export
Number realize the start and stop of motor to controller.
Compared with prior art, this utility model has the advantages that
The optically-based microscope of this utility model, by being provided for the turnover storehouse of the mobile film magazine placing checking matter smear
Mechanism, pushing mechanism and elevator mechanism, for controlling the object stage of checking matter accurately image, Z axis guiding mechanism and turret,
And checking matter imaging is carried out image procossing, the computer of detection identification, it is achieved that the fully-automated synthesis identification to checking matter.
This utility model automaticity is high, enormously simplify detection program, reduces because of the subjectivity of manual detection and lacks experience
The error brought, improves detection speed and efficiency, reduces personnel labor intensity, saved human resources.
Accompanying drawing explanation
Fig. 1 is composition frame chart based on microscopical automatic detection system.
Detailed description of the invention
With embodiment, this utility model is described further below in conjunction with the accompanying drawings.
A kind of based on microscopical automatic detection system, its composition is as it is shown in figure 1, include the machinery being arranged on base
System, optical microscope and be the mechanical system control system of motor that provides power for controlling, also include being arranged on
CCD camera in optical microscope frame, and the computer processed for data being positioned at outside base.Mechanical system is by tested
Thing smear moves under optical microscope, and the light that the light source of optical microscope sends passes checking matter smear, through object lens in CCD phase
Focal imaging on the electronic eyepiece of machine, CCD camera is sent to computer after the optical signalling of imaging is converted into the signal of telecommunication and enters
Row image procossing and detection.
Mechanical system includes being arranged on base places the barn in-and-out machine structure of film magazine of checking matter smear, push jack for mobile
Mechanism, elevator mechanism, be arranged on the object stage in optical microscope frame, Z axis guiding mechanism, turret.
Barn in-and-out machine structure includes passing in and out storehouse motor and by the stepper motor driven conveyer belt being positioned at upper strata in turnover storehouse
Be positioned at the crank connecting link of lower floor, used for conveyer belt in mobile film magazine, crank connecting link for the film magazine that will detect from barn in-and-out machine
Structure is fetched.
Pushing mechanism includes push jack motor and push jack framework.The connecting plate of push jack framework is connected to profile of tooth by pressure zone plate
On band, push jack step motor drive cog belt does back and forth movement.Push jack framework is divided into upper and lower two-layer, pushing away of upper strata push jack framework
Film magazine is shifted onto in the box torr of elevator mechanism by plate by barn in-and-out machine structure, and completes checking matter smear and go out, enter the operation of film magazine；Lower floor
Film magazine is pushed back below elevator mechanism by the hook plate of push jack framework.
Elevator mechanism includes elevator motor, screw pair, line slideway auxiliary and support thereof, and elevator motor leads to
Crossing cog belt drives screw pair to drive the box torr placing film magazine to do vertical motion on line slideway auxiliary.Support is provided with
The side lay of film magazine, side lay is joined with the telescopic shaft with stage clip by the pressing plate being arranged in fixed plate
Closing, unclamp film magazine from the side of two positions of film magazine vertical direction motion, remaining position compresses film magazine.
Object stage is connected with the object stage supporting plate of optical microscope by pedestal.Object stage motor is by driving leading screw
Pair of nut makes object stage carry out the motion of X, Y-direction on line slideway auxiliary, and by checking matter smear, from delivery position, (checking matter is coated with
Sheet moves to original position during object stage) mobile to image space.Control system utilizes the Displacement Feedback of the grating output of X, Y-axis
Signal carries out closed loop control to object stage motor, and the positioning precision making object stage meet imaging in the motion of X, Y-direction is wanted
Ask.
Z axis guiding mechanism is for realizing the focusing of optical microscope, including fine-tuning mechanism and coarse adjustment mechanism, coarse adjustment mechanism by
Z axis adjusts step motor drive cog belt thus controls the lifting of object stage；Fine-tuning mechanism is directly connected to microscope Z axis, controls
System utilizes the Displacement Feedback signal of the grating encoder output being arranged on Z axis that Z axis adjustment motor is carried out closed loop control,
The lifting making thing platform meets the required precision focused on.
Turret includes turret rotating mechanism and barcode scanner.Turret rotating mechanism is by turret
Step motor drive cog belt thus drive turret to rotate, control system utilize be arranged on turret motor rear portion
Grating encoder, output displacement feedback signal carries out closed loop control to turret motor, it is achieved the thing of different multiples
The conversion of mirror.Barcode scanner is for obtaining the barcode identification information on checking matter smear.
Mechanical system also includes the syringe pump mechanism being arranged on base, and syringe pump mechanism includes oil bottle, syringe pump and note
Penetrate pump motor；Syringe pump motor drives screw mandrel to drive syringe pump to move reciprocatingly, by oil droplet to quilt by cog belt
Imaging region on inspection thing smear, makes image clear.
Control system includes driver, controller, grating encoder and lead limit switch；The pulse letter of controller output
Number through driver amplify rear drive motor rotate；Controller utilizes displacement signal that grating encoder feeds back to motor
Carry out closed loop control；Lead limit switch feedback limit position signalling controls signal to controller to computer, computer export
Realize the start and stop of motor.
The detection of applying described in the utility model detecting system carry out medical cell morphological form Classification and Identification is presented herein below
Flow process:
15 clinical medicine smears are put in film magazine, film magazine are placed on the conveyer belt on barn in-and-out machine structure upper strata by step 1
On；Film magazine is transported to pass in and out storehouse high order end by the conveyer belt of barn in-and-out machine structure；Film magazine is shifted onto the box of elevator mechanism by pushing mechanism
In torr, pushing mechanism is return；Elevator mechanism drops to the 1st clinical medicine smear position, and pushing mechanism is by the 1st clinical medicine
Film magazine released by smear, pushes object stage delivery position and positions.
Step 2, object stage is in X, Y, Z-direction motion, and clinical medicine smear light moves to learn below microscopical camera lens, bar shaped
Code scanner scans the bar code of clinical medicine smear and delivers to computer identification.
Step 3, the high light line of spotlight irradiates clinical medicine smear detection region, and light is put through 10 times of object lens of microscope
Greatly, through object stage Z-direction motion focal imaging, CCD camera imagery optical signal deliver to computer after being converted to the signal of telecommunication,
The area of visual field of selected 100 cells after being judged by computer；Object stage moves in X direction, and syringe pump mechanism is to medical science
Clinical smear oil dripping, object stage returns in X direction；Turret 100 times of object lens of conversion, focus on through object stage Z-direction accurate adjustment
Imaging, CCD camera after sending computer to process after 100 times of object lens imagery optical signals being converted to the signal of telecommunication；Object stage
Carry out X, Y-direction battlement shape fine motion, gather image and send computer disposal；Computer completes all images and processes；Turret changes
Returning 10 times of object lens, object stage makes clinical medicine smear by returning to object stage immediately below microscope objective in X, Y, Z-direction motion
Delivery position.
Step 4, pushing mechanism returns certain distance after clinical medicine smear is pushed back film magazine；Elevator mechanism drops to the 2nd
Individual clinical medicine smear position.
Step 5, circulation step 1～4, the detection of whole clinical medicine smears in completing first film magazine.Under elevator mechanism
Dropping to bottom, film magazine is pushed back barn in-and-out machine structure lower floor by pushing mechanism, and film magazine is fetched by the toggle of barn in-and-out machine structure,
2nd film magazine is pushed in the box torr of elevator mechanism by the high order end that delivers from godown by the conveyer belt of barn in-and-out machine structure simultaneously, starts the 2nd sheet
The detection of box.So circulation is until completing the detection of whole film magazine.
This utility model is not limited to above-mentioned embodiment, and it is any to above-mentioned embodiment that those skilled in the art are made
Conspicuously improved or change, all without the protection domain beyond design of the present utility model and claims.
Claims (10)
1. one kind based on microscopical automatic detection system, it is characterised in that include mechanical system, the light being arranged on base
Learn microscope and for controlling to provide for mechanical system the control system of the motor of power, also include being arranged on optical microphotograph
CCD camera on illuminating apparatus frame, and the computer being positioned at outside base；Checking matter smear is moved to optical microscope by mechanical system
Under, the light that the light source of optical microscope sends passes checking matter smear, is focused on the electronic eyepiece of CCD camera through object lens
Picture, CCD camera is sent to computer and carries out image procossing and detection after the optical signalling of imaging is converted into the signal of telecommunication.
The most according to claim 1 based on microscopical automatic detection system, it is characterised in that mechanical system includes peace
It is contained on base and places the barn in-and-out machine structure of film magazine of checking matter smear, pushing mechanism, elevator mechanism for mobile, be arranged on light
Learn the object stage on microscope frame, Z axis guiding mechanism, turret.
The most according to claim 2 based on microscopical automatic detection system, it is characterised in that barn in-and-out machine structure includes
Pass in and out storehouse motor and connected with the crank being positioned at lower floor by the stepper motor driven conveyer belt being positioned at upper strata in described turnover storehouse
Bar, used for conveyer belt in mobile film magazine, crank connecting link is for fetching the film magazine detected from barn in-and-out machine structure.
The most according to claim 2 based on microscopical automatic detection system, it is characterised in that pushing mechanism includes pushing away
Sheet motor and push jack framework；The connecting plate of push jack framework is connected on cog belt by pressure zone plate, push jack step motor drive
Cog belt does back and forth movement；Push jack framework is divided into upper and lower two-layer, the push pedal of upper strata push jack framework to be pushed away by barn in-and-out machine structure by film magazine
In the box torr of elevator mechanism, and complete checking matter smear and go out, enter the operation of film magazine；The hook plate of lower floor's push jack framework by film magazine from
Push back below elevator mechanism.
The most according to claim 2 based on microscopical automatic detection system, it is characterised in that elevator mechanism includes electricity
Ladder motor, screw pair, line slideway auxiliary and support thereof, elevator motor drives screw pair by cog belt
The box torr placing film magazine is driven to do vertical motion on line slideway auxiliary；Support is provided with the side lay of film magazine, side
Face positioner is coordinated with the telescopic shaft with stage clip by the pressing plate being arranged in fixed plate, from the motion of film magazine vertical direction
Film magazine is unclamped in the side of two positions, and remaining position compresses film magazine.
The most according to claim 2 based on microscopical automatic detection system, it is characterised in that object stage shows with optics
The object stage supporting plate of micro mirror is connected；Object stage motor makes object stage enterprising at line slideway auxiliary by driving screw pair
Row X, the motion of Y-direction, move checking matter smear to image space from delivery position；Control system utilizes the grating of X, Y-axis
The Displacement Feedback signal of encoder output carries out closed loop control to object stage motor, makes object stage in X, the motion of Y-direction
Meet the positioning accuracy request of imaging.
The most according to claim 2 based on microscopical automatic detection system, it is characterised in that Z axis guiding mechanism is used
In realizing the focusing of optical microscope, including fine-tuning mechanism and coarse adjustment mechanism, coarse adjustment mechanism is adjusted step motor drive tooth by Z axis
Shape band thus control the lifting of object stage；Fine-tuning mechanism is directly connected to microscope Z axis, and control system utilizes the light being arranged on Z axis
The Displacement Feedback signal of grid encoder output adjusts motor to Z axis and carries out closed loop control, makes the lifting of thing platform meet and focuses on
Required precision.
The most according to claim 2 based on microscopical automatic detection system, it is characterised in that turret includes thing
Mirror rotating mechanism and barcode scanner；Turret rotating mechanism is by turret step motor drive cog belt thus drives
Turret rotates, and control system utilizes the grating encoder being arranged on turret motor rear portion, and output displacement feeds back
Signal carries out closed loop control to turret motor, it is achieved the conversion of the object lens of different multiples；Barcode scanner is used for
Obtain the barcode identification information on checking matter smear.
The most according to claim 2 based on microscopical automatic detection system, it is characterised in that mechanical system also includes
The syringe pump mechanism being arranged on base, syringe pump mechanism includes oil bottle, syringe pump and syringe pump motor；Syringe pump stepping
Motor drives screw mandrel to drive syringe pump to move reciprocatingly by cog belt, by the imaging region on oil droplet to checking matter smear, makes
Image is clear.
The most according to claim 1 based on microscopical automatic detection system, it is characterised in that control system includes
Driver, controller, grating encoder and lead limit switch；The pulse signal of controller output amplifies rear drive through driver
Motor rotates；The displacement signal that controller utilizes grating encoder to feed back carries out closed loop control to motor；Stroke limits
Bit switch feedback limit position signalling to computer, computer export control signal to controller realize the startup of motor with
Stop.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201620735059.XU CN205787345U (en) | 2016-07-12 | 2016-07-12 | A kind of based on microscopical automatic detection system |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201620735059.XU CN205787345U (en) | 2016-07-12 | 2016-07-12 | A kind of based on microscopical automatic detection system |
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| Publication Number | Publication Date |
|---|---|
| CN205787345U true CN205787345U (en) | 2016-12-07 |
Family
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201620735059.XU Withdrawn - After Issue CN205787345U (en) | 2016-07-12 | 2016-07-12 | A kind of based on microscopical automatic detection system |
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| CN (1) | CN205787345U (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107645119A (en) * | 2017-10-18 | 2018-01-30 | 哈尔滨工业大学 | A kind of method of computer control laser output wavelength |
| CN105988209B (en) * | 2016-07-12 | 2018-09-18 | 江苏赛尔蒂扶医疗科技有限公司 | One kind being based on microscopical automatic detection system |
-
2016
- 2016-07-12 CN CN201620735059.XU patent/CN205787345U/en not_active Withdrawn - After Issue
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105988209B (en) * | 2016-07-12 | 2018-09-18 | 江苏赛尔蒂扶医疗科技有限公司 | One kind being based on microscopical automatic detection system |
| CN107645119A (en) * | 2017-10-18 | 2018-01-30 | 哈尔滨工业大学 | A kind of method of computer control laser output wavelength |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| AV01 | Patent right actively abandoned | ||
| AV01 | Patent right actively abandoned |
Granted publication date: 20161207 Effective date of abandoning: 20180918 |