CN1864058B - 芯片的使用方法及检查芯片 - Google Patents
芯片的使用方法及检查芯片 Download PDFInfo
- Publication number
- CN1864058B CN1864058B CN2004800289463A CN200480028946A CN1864058B CN 1864058 B CN1864058 B CN 1864058B CN 2004800289463 A CN2004800289463 A CN 2004800289463A CN 200480028946 A CN200480028946 A CN 200480028946A CN 1864058 B CN1864058 B CN 1864058B
- Authority
- CN
- China
- Prior art keywords
- weighing
- rotating shaft
- mentioned
- object component
- separating tube
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
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Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502753—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by bulk separation arrangements on lab-on-a-chip devices, e.g. for filtration or centrifugation
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502746—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means for controlling flow resistance, e.g. flow controllers, baffles
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/06—Fluid handling related problems
- B01L2200/0621—Control of the sequence of chambers filled or emptied
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/10—Integrating sample preparation and analysis in single entity, e.g. lab-on-a-chip concept
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/0627—Sensor or part of a sensor is integrated
- B01L2300/0654—Lenses; Optical fibres
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/0672—Integrated piercing tool
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0803—Disc shape
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0809—Geometry, shape and general structure rectangular shaped
- B01L2300/0816—Cards, e.g. flat sample carriers usually with flow in two horizontal directions
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
- B01L2300/0864—Configuration of multiple channels and/or chambers in a single devices comprising only one inlet and multiple receiving wells, e.g. for separation, splitting
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
- B01L2300/087—Multiple sequential chambers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
- B01L2400/0409—Moving fluids with specific forces or mechanical means specific forces centrifugal forces
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
- B01L2400/0478—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure pistons
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/06—Valves, specific forms thereof
- B01L2400/0677—Valves, specific forms thereof phase change valves; Meltable, freezing, dissolvable plugs; Destructible barriers
- B01L2400/0683—Valves, specific forms thereof phase change valves; Meltable, freezing, dissolvable plugs; Destructible barriers mechanically breaking a wall or membrane within a channel or chamber
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/08—Regulating or influencing the flow resistance
- B01L2400/084—Passive control of flow resistance
- B01L2400/086—Passive control of flow resistance using baffles or other fixed flow obstructions
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502738—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by integrated valves
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Clinical Laboratory Science (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Dispersion Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
- Sampling And Sample Adjustment (AREA)
- Centrifugal Separators (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
Abstract
Description
Claims (3)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP346439/2003 | 2003-10-03 | ||
JP2003346439 | 2003-10-03 | ||
PCT/JP2004/014988 WO2005033666A1 (ja) | 2003-10-03 | 2004-10-04 | チップの使用方法及び検査チップ |
Publications (2)
Publication Number | Publication Date |
---|---|
CN1864058A CN1864058A (zh) | 2006-11-15 |
CN1864058B true CN1864058B (zh) | 2012-07-18 |
Family
ID=34419545
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN2004800289463A Expired - Fee Related CN1864058B (zh) | 2003-10-03 | 2004-10-04 | 芯片的使用方法及检查芯片 |
Country Status (5)
Country | Link |
---|---|
US (2) | US7691328B2 (zh) |
EP (1) | EP1669733B1 (zh) |
JP (1) | JP4336834B2 (zh) |
CN (1) | CN1864058B (zh) |
WO (1) | WO2005033666A1 (zh) |
Families Citing this family (48)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20070095393A1 (en) * | 2004-03-30 | 2007-05-03 | Piero Zucchelli | Devices and methods for programmable microscale manipulation of fluids |
JP4375183B2 (ja) * | 2004-09-22 | 2009-12-02 | ウシオ電機株式会社 | マイクロチップ |
CN101073003B (zh) * | 2004-12-08 | 2011-07-06 | 松下电器产业株式会社 | 生物样品分析用板 |
JP4745741B2 (ja) * | 2005-07-12 | 2011-08-10 | 日本特殊陶業株式会社 | 中継基板、及びマイクロチップ搭載装置 |
JP4771864B2 (ja) * | 2006-05-31 | 2011-09-14 | ローム株式会社 | 生化学分析装置 |
JP4901333B2 (ja) | 2006-06-30 | 2012-03-21 | ローム株式会社 | マイクロチップ検査装置 |
JP4880419B2 (ja) * | 2006-10-18 | 2012-02-22 | ローム株式会社 | 計量部を有するチップおよびこれを用いた液体試料の計量方法 |
JP5004577B2 (ja) * | 2006-12-27 | 2012-08-22 | ローム株式会社 | 液体試薬内蔵型マイクロチップにおける液体試薬の液量および/または品質が正常であるかを判定する方法、および液体試薬内蔵型マイクロチップ |
JP5137007B2 (ja) * | 2007-11-14 | 2013-02-06 | ローム株式会社 | マイクロチップ |
US8075853B2 (en) * | 2007-11-16 | 2011-12-13 | Rohm Co., Ltd. | Microchip |
JP5137014B2 (ja) * | 2007-12-28 | 2013-02-06 | ローム株式会社 | マイクロチップ |
JP5077945B2 (ja) * | 2007-12-27 | 2012-11-21 | ローム株式会社 | マイクロチップ |
JP5172461B2 (ja) * | 2008-05-13 | 2013-03-27 | ローム株式会社 | マイクロチップ |
JP5137011B2 (ja) * | 2007-12-26 | 2013-02-06 | ローム株式会社 | マイクロチップ |
JP4665960B2 (ja) * | 2007-12-06 | 2011-04-06 | セイコーエプソン株式会社 | 生体試料反応用チップ、生体試料反応装置、および生体試料反応方法 |
JP5137012B2 (ja) * | 2007-12-27 | 2013-02-06 | ローム株式会社 | マイクロチップ |
CN101925820B (zh) * | 2008-01-28 | 2014-02-12 | 东丽株式会社 | 分离芯片和分离方法 |
US8486336B2 (en) * | 2008-04-18 | 2013-07-16 | Rohm Co., Ltd. | Microchip |
US20090291025A1 (en) * | 2008-05-20 | 2009-11-26 | Rohm Co., Ltd. | Microchip And Method Of Using The Same |
WO2010007733A1 (ja) * | 2008-07-17 | 2010-01-21 | パナソニック株式会社 | 分析用デバイスとこの分析用デバイスを使用した分析方法 |
JPWO2010038897A1 (ja) * | 2008-10-05 | 2012-03-01 | アークレイ株式会社 | 分析用具およびその製造方法 |
JP5311406B2 (ja) * | 2009-09-10 | 2013-10-09 | 独立行政法人産業技術総合研究所 | 免疫センサ |
DE102009048378B3 (de) * | 2009-10-06 | 2011-02-17 | INSTITUT FüR MIKROTECHNIK MAINZ GMBH | Mikrofluidische Struktur |
FR2954332B1 (fr) | 2009-12-22 | 2012-01-13 | Michelin Soc Tech | Article notamment pneumatique avec melange de caoutchouc externe comportant un sel de lanthanide |
NO332016B1 (no) * | 2009-12-29 | 2012-05-21 | Stiftelsen Sintef | Prøvebehandlingskassett og fremgangsmåte for å behandle og/eller analysere en prøve under sentrifugalkraft |
JP5359964B2 (ja) * | 2010-03-31 | 2013-12-04 | ブラザー工業株式会社 | 検査対象受体、検査装置及び検査方法 |
JP6017793B2 (ja) * | 2012-02-09 | 2016-11-02 | ローム株式会社 | マイクロチップ |
JP2013205282A (ja) * | 2012-03-29 | 2013-10-07 | Brother Ind Ltd | 検査対象受体、検査装置および検査方法 |
JP6001418B2 (ja) * | 2012-11-02 | 2016-10-05 | パナソニックヘルスケアホールディングス株式会社 | 生体化学分析用の処理チップ |
WO2013172003A1 (ja) | 2012-05-16 | 2013-11-21 | パナソニック株式会社 | 生体検出チップおよびこれを備えた生体検出装置 |
CN103890591B (zh) * | 2012-07-24 | 2016-08-24 | 松下健康医疗控股株式会社 | 分析用仪器 |
JP5998760B2 (ja) * | 2012-08-31 | 2016-09-28 | ブラザー工業株式会社 | 試薬容器および検査チップ |
WO2014069551A1 (ja) * | 2012-10-31 | 2014-05-08 | 日立化成株式会社 | センサチップ及びそれを用いた測定装置,測定方法 |
JP5971082B2 (ja) * | 2012-10-31 | 2016-08-17 | ブラザー工業株式会社 | 検査チップ |
WO2015170753A1 (ja) * | 2014-05-08 | 2015-11-12 | 国立大学法人大阪大学 | 熱対流生成用チップ及び液体秤量具 |
CN105327722B (zh) * | 2014-05-30 | 2019-03-19 | 科宝智慧医疗科技(上海)有限公司 | 用于分析液体的容器 |
KR101859860B1 (ko) * | 2014-06-06 | 2018-05-18 | 에프. 호프만-라 로슈 아게 | 생물학적 샘플을 분석하기 위한 계측 챔버를 갖는 회전 가능한 카트리지 |
EP2952258A1 (en) * | 2014-06-06 | 2015-12-09 | Roche Diagnostics GmbH | Rotatable cartridge for analyzing a biological sample |
EP2952257A1 (en) * | 2014-06-06 | 2015-12-09 | Roche Diagnostics GmbH | Rotatable cartridge for processing and analyzing a biological sample |
EP2957890A1 (en) * | 2014-06-16 | 2015-12-23 | Roche Diagnostics GmbH | Cartridge with a rotatable lid |
JP6164186B2 (ja) * | 2014-09-30 | 2017-07-19 | ブラザー工業株式会社 | 検査装置、検査プログラム、検査方法 |
TWI545323B (zh) * | 2014-10-31 | 2016-08-11 | 紹興普施康生物科技有限公司 | 一種離心式磁性粒子操縱與檢測裝置及其運作方法 |
CN107305210B (zh) | 2016-04-20 | 2019-09-17 | 光宝电子(广州)有限公司 | 生物检测卡匣及其检测流体的流动方法 |
US20190240655A1 (en) * | 2016-09-14 | 2019-08-08 | Sekisui Chemical Co., Ltd. | Microchip |
CN109821584B (zh) * | 2019-03-26 | 2021-08-31 | 京东方科技集团股份有限公司 | 微流控芯片及其检测方法和制作方法 |
WO2022124070A1 (ja) * | 2020-12-11 | 2022-06-16 | 株式会社堀場製作所 | 検査装置、情報処理方法およびプログラム |
EP4124385A1 (en) * | 2021-07-26 | 2023-02-01 | Helaxy Inc. | Assembly and method for combined nucleic acid purification and amplification |
FR3138351A1 (fr) | 2022-07-29 | 2024-02-02 | Compagnie Generale Des Etablissements Michelin | Pneumatique à armature de carcasse radiale |
Citations (3)
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---|---|---|---|---|
CN86108549A (zh) * | 1985-12-20 | 1987-06-17 | 古甘·简 | 从用于分析的血样中提取预定量的血浆的方法和设备 |
US4892708A (en) * | 1987-07-01 | 1990-01-09 | Miles Inc. | Fluid separation and processing device |
CN1058551A (zh) * | 1990-08-03 | 1992-02-12 | 让·吉根 | 用离心分离法分离全血中血浆的装置 |
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US4883763A (en) | 1984-05-03 | 1989-11-28 | Abbott Laboratories | Sample processor card for centrifuge |
US4812294A (en) * | 1986-02-28 | 1989-03-14 | Automated Diagnostic Systems, Inc. | Specimen processing system |
US5286454A (en) * | 1989-04-26 | 1994-02-15 | Nilsson Sven Erik | Cuvette |
GB9620278D0 (en) * | 1996-09-28 | 1996-11-13 | Central Research Lab Ltd | Apparatus for chemical analysis |
AU7591998A (en) * | 1997-05-23 | 1998-12-11 | Gamera Bioscience Corporation | Devices and methods for using centripetal acceleration to drive fluid movement in a microfluidics system |
JP2003533682A (ja) * | 2000-05-15 | 2003-11-11 | テカン・トレーディング・アクチェンゲゼルシャフト | 双方向流動遠心ミクロ流体装置 |
SE0100952D0 (sv) * | 2001-03-19 | 2001-03-19 | Gyros Ab | A microfluidic system (MS) |
US6919058B2 (en) * | 2001-08-28 | 2005-07-19 | Gyros Ab | Retaining microfluidic microcavity and other microfluidic structures |
JP2003083958A (ja) | 2001-09-11 | 2003-03-19 | Jun Kikuchi | 血液分析装置ならびに血液分析方法 |
US7041258B2 (en) * | 2002-07-26 | 2006-05-09 | Applera Corporation | Micro-channel design features that facilitate centripetal fluid transfer |
JP2004109099A (ja) * | 2002-09-16 | 2004-04-08 | Jun Kikuchi | 血液分析方法、血液分析装置および血液分析装置の製造方法 |
JP3803078B2 (ja) | 2002-09-20 | 2006-08-02 | 独立行政法人科学技術振興機構 | 血液分析装置及び血漿分離方法 |
-
2004
- 2004-10-04 JP JP2005514516A patent/JP4336834B2/ja active Active
- 2004-10-04 WO PCT/JP2004/014988 patent/WO2005033666A1/ja active Application Filing
- 2004-10-04 CN CN2004800289463A patent/CN1864058B/zh not_active Expired - Fee Related
- 2004-10-04 EP EP04773719.2A patent/EP1669733B1/en active Active
- 2004-10-04 US US10/595,262 patent/US7691328B2/en active Active
-
2010
- 2010-02-17 US US12/707,399 patent/US7972577B2/en active Active
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN86108549A (zh) * | 1985-12-20 | 1987-06-17 | 古甘·简 | 从用于分析的血样中提取预定量的血浆的方法和设备 |
US4892708A (en) * | 1987-07-01 | 1990-01-09 | Miles Inc. | Fluid separation and processing device |
CN1058551A (zh) * | 1990-08-03 | 1992-02-12 | 让·吉根 | 用离心分离法分离全血中血浆的装置 |
Non-Patent Citations (4)
Title |
---|
US 4892708 A,全文. |
全文. |
兰炯采,刘忠,甘茂州,陈强,张印则,孟庆宝.脐血单个核细胞的分离及冻存.中国实验血液学杂志10 4.2002,10(4),351-354. |
兰炯采,刘忠,甘茂州,陈强,张印则,孟庆宝.脐血单个核细胞的分离及冻存.中国实验血液学杂志10 4.2002,10(4),351-354. * |
Also Published As
Publication number | Publication date |
---|---|
US7691328B2 (en) | 2010-04-06 |
US20100158757A1 (en) | 2010-06-24 |
US7972577B2 (en) | 2011-07-05 |
EP1669733A1 (en) | 2006-06-14 |
EP1669733B1 (en) | 2019-01-16 |
EP1669733A4 (en) | 2012-11-21 |
CN1864058A (zh) | 2006-11-15 |
WO2005033666A1 (ja) | 2005-04-14 |
JP4336834B2 (ja) | 2009-09-30 |
JPWO2005033666A1 (ja) | 2007-11-15 |
US20070003433A1 (en) | 2007-01-04 |
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