CN1843499A - Traditional Chinese medicine formulation for treating bronchitis and tonsillitis - Google Patents
Traditional Chinese medicine formulation for treating bronchitis and tonsillitis Download PDFInfo
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Abstract
The invention provides a Chinese medicinal preparation for treating bronchitis and tonsillitis, which is prepared from the following Chinese medicinal herbs including (by weight ratio): polygala root 12-18, roor of sessile stemona 12-18, root of balloonflower 8-12, ephedra sinica stapf 7-11, apricot kernel 8-12, and licorice root 7-11, cordate houttuynia 12-18, lepidium seed 8-12, perilla fruit 8-12, peucedanum root 8-12, silver flower 12-18, capsule of weeping forsythia 12-18, root of large-flowered skullcap 9-15, dried orange peel 10-15, arctium fruit 10-15, beach silvertop root 10-15, asarum herb 3-7, dried ginger 4-8 and poria cocos wolf 12-18.
Description
Technical field
The invention belongs to pharmaceutical product, particularly a kind of to treatment treatment bronchitis and tonsillitic specific Chinese medicine preparation.
Background technology
Tonsillitis and bronchitis all are the common and frequently-occurring diseases of respiratory tract, by being child and between twenty and fifty in the majority.Basic medicine all is to take to take or inject antibiotics class medicine such as penicillin, though the merit in a period of time can be arranged, causes outbreak repeatedly easily.And it is irritated easily to this type of antibiotic medicine to be difficult to many people, causes the scope of application to be restricted.Have a lot of Chinese medicine preparation to be used for treating these diseases at present, but all come with some shortcomings, perhaps drug ratio too complexity cause cost higher, perhaps filling a prescription, too simple effects is relatively poor.
Summary of the invention
The object of the invention provides a kind ofly both can have the effect of getting instant result to tonsillitis and tracheitis, and the pure Chinese medicinal preparation that can up to standardly effect a permanent cure is arranged.
Modern medicine is thought: tonsillitis is many to cause the red and swollen inflammation of tonsil by pathogenic bacterial infections such as Hemolytic streptococcus, staphylococcus, Diplococcus pneumoniaes.Clinical manifestation is red swelling of the pharynx, pain, the dried discomfort of itching, pharyngeal tonsils redness and foreign body sensation, and often with heating paresthesia, the traditional Chinese medical science thinks that it belongs to disease categories such as acute tonsillitis, acute tonsillitis caused by pathogenic windheat.Bronchitis then is because infection or non-infective agent cause the chronic nonspecific inflammation of trachea and bronchus mucosa and surrounding tissue thereof.Bronchus body of gland hypertrophy, mucous secretion increase, and stimulate bronchial mucosa to cause bronchospasm, and airway constriction, resistance increase, and clinical manifestation is for coughing, expectorant, breathing heavily.Can cause the immunologic function degeneration for a long time.And motherland's medical science is thought: bronchitis belongs to chronic cough phlegm retention scope, and is closely related with lung, spleen, kidney three dirty all void.
According to above theory, the selected expelling phlegm for arresting cough of the present invention, lung moistening, detoxifcation heat clearing away and the only cold medicine that dispels the wind are formed a kind of treatment bronchitis of the present invention and tonsillitic Chinese medicine preparation, and its raw material of Chinese medicine by following weight parts is made:
Radix Polygalae 12-18, Radix Asteris 12-18, Radix Stemonae 12-18, Radix Platycodonis 8-12, Flos Farfarae 12-18, Herba Ephedrae (processed) 7-11, Semen Armeniacae Amarum 8-12, Radix Glycyrrhizae 7-11, Herba Houttuyniae 12-18, Semen Lepidii (Semen Descurainiae) 8-12, Fructus Perillae 8-12, Radix Peucedani 8-12, Flos Lonicerae 12-18, Fructus Forsythiae 12-18, Radix Scutellariae 9-15, Pericarpium Citri Reticulatae 10-15, Fructus Arctii 10-15, Radix Glehniae 10-15, Herba Asari 3-7, Rhizoma Zingiberis 4-8, Poria 12-18.
Preferential each components by weight of prescription of recommending of the present invention is:
Radix Polygalae 15, Radix Asteris 15, the Radix Stemonae 15, Radix Platycodonis 10, Flos Farfarae 15, Herba Ephedrae (processed) 9, Semen Armeniacae Amarum 10, Radix Glycyrrhizae 9, Herba Houttuyniae 15, Semen Lepidii (Semen Descurainiae) 10, Fructus Perillae 10, Radix Peucedani 10, Flos Lonicerae 15, Fructus Forsythiae 15, Radix Scutellariae 12, Pericarpium Citri Reticulatae 13, Fructus Arctii 13, Radix Glehniae 13, Herba Asari 5, Rhizoma Zingiberis 6, Poria 15.
The main pharmacological of each herbal medicine is as follows among the present invention: Radix Polygalae---tranquilizing by nourishing the heart, expelling phlegm for arresting cough; Radix Asteris---nourishing the lung to keep the adverse QI downward, preventing phlegm from forming and stopping coughing; The Radix Stemonae---nourishing the lung to arrest cough, the delousing parasite killing; Radix Platycodonis---lung qi dispersing eliminates the phlegm, and arranges the dense pain that disappears; Flos Farfarae---nourishing the lung to arrest cough, the expectorant therapeutic method to keep the adverse QI flowing downwards; Herba Ephedrae (processed)---relieving the exterior syndrome by diaphoresis, depressed lung-energy dispersing, diuretic detumescent; Semen Armeniacae Amarum---relieving cough and asthma, loosening bowel to relieve constipation; Radix Glycyrrhizae---invigorating the spleen and replenishing QI, expelling phlegm for arresting cough, relieving spasm to stop pain, heat-clearing and toxic substances removing, the mediation property of medicine; Herba Houttuyniae---separate pyretic toxicity, the pain that disappears is swollen, inducing diuresis for treating stranguria syndrome; Semen Lepidii (Semen Descurainiae)---eliminating phlegm and relieving asthma, therapeutic method to keep the adverse QI flowing downwards row water; Fructus Perillae---relieving cough and asthma, therapeutic method to keep the adverse QI flowing downwards expectorant; Radix Peucedani--the expectorant of-sending down the abnormal ascending QI, dispelling wind-heat; Flos Lonicerae---heat-clearing and toxic substances removing, eliminating pathogenic heat from blood to cure dysentery; Fructus Forsythiae---heat-clearing and toxic substances removing, the eliminating stagnation of relieving inflammation or internal heat; Radix Scutellariae---clearing away heat-fire, dampness, pathogenic fire reducing; Pericarpium Citri Reticulatae---drying dampness to eliminate phlegm, regulating qi-flowing for strengthening spleen; Fructus Arctii---dispelling wind and heat pathogens, sore-throat relieving eliminating stagnation, lung qi dispersing rash, toxin expelling detumescence; Radix Glehniae---nourishing the lung to arrest cough, nourishing the stomach to promote the production of body fluid; Herba Asari---expelling cold and relieving exterior syndrome, wind-expelling pain-stopping; Rhizoma Zingiberis---warming middle-JIAO a surname sun, warming the lung for resolving phlegm; Poria---diuretic is wet, spleen invigorating invigorating middle warmer, mind tranquilizing and the heart calming.
Inventor research is thought: chronic bronchitis is often because of due to the multiple factor comprehensive and long-term action.Onset and flu have substantial connection, how in the more violent morbidity in season of climate change.Respiratory tract viral infection and Secondary cases bacterial infection repeatedly is to cause chronic bronchitis to become the major reason that development and disease increase the weight of.The relation of smoking and chronic bronchitis also is sure, and the smoker is higher 2～8 times than non-smoker's prevalence, and the smoking time, day smoking capacity was bigger more for a long time, and prevalence is higher, and smoking cessation can make the state of an illness alleviate.In addition, contacting industrial dust, atmospheric pollution and irritated factor for a long time also often is the reason that causes chronic bronchitis, and Abwehrkraft des Koepers reduces, and the respiratory system defense function is impaired then to be the intrinsic factor of morbidity.Chronic bronchitis can be divided into simple type and the type amphitypy of panting clinically.Simple type mainly shows as cough, expectoration: pants type person and except that cough, expectoration are arranged, still has and pant,, stridulate and when apasm of coughing, aggravate with wheezing sound, and obvious during sleep.
Therefore prescription of the present invention has warming the kidney to activate YANG, drying damp and strengthening spleen, reduces phlegm, cough-relieving, the merit of relievining asthma, and suppresses or killing action causing that tonsillitic streptococcus pneumoniae, bloodthirsty hemophilus influenza, tubercule bacillus etc. also have; Strengthen patient's immunity, improve the resistivity and the resisting cold ability of respiratory tract, reach the purpose of fundamentally treating chronic bronchitis.Medicine of the present invention is nontoxic through animal and chronic toxicity test proof, meets sanitary index simultaneously.
The specific embodiment:
Embodiment 1: a kind of treatment bronchitis and tonsillitic Chinese medicine preparation, and its raw material of Chinese medicine by following weight parts is made:
Radix Polygalae 12, Radix Asteris 18, the Radix Stemonae 12, Radix Platycodonis 12, Flos Farfarae 12, Herba Ephedrae (processed) 11, Semen Armeniacae Amarum 8, Radix Glycyrrhizae 11, Herba Houttuyniae 12, Semen Lepidii (Semen Descurainiae) 12, Fructus Perillae 8, Radix Peucedani 12, Flos Lonicerae 12, Fructus Forsythiae 18, Radix Scutellariae 9, Pericarpium Citri Reticulatae 15, Fructus Arctii 10, Radix Glehniae 15, Herba Asari 3, Rhizoma Zingiberis 8, Poria 12.
Above-mentioned medicaments in part by weight is cleaned up after drying and be crushed to more than 100 orders, incapsulate after the mixing and get final product.
Embodiment 2:
Radix Polygalae 18, Radix Asteris 12, the Radix Stemonae 18, Radix Platycodonis 8, Flos Farfarae 18, Herba Ephedrae (processed) 7, Semen Armeniacae Amarum 12, Radix Glycyrrhizae 7, Herba Houttuyniae 18, Semen Lepidii (Semen Descurainiae) 8, Fructus Perillae 12, Radix Peucedani 8, Flos Lonicerae 18, Fructus Forsythiae 12, Radix Scutellariae 15, Pericarpium Citri Reticulatae 10, Fructus Arctii 15, Radix Glehniae 10, Herba Asari 7, Rhizoma Zingiberis 4, Poria 18.
Above-mentioned medicaments in part by weight is cleaned up after drying and be crushed to more than 200 orders, pack into the direct warm water of powder and take after mixing it with water.
Below be embodiment of the invention treatment bronchitis and tonsillitic clinical report.
Preparation for treating respiratory tract of the present invention and disease of tracheitis 136 routine clinical datas
One, physical data: the hospital outpatient patient is totally 136 examples, male 78 examples, and women 58 examples, 14～51 years old age, average 35.6 years old, the course of disease 1～3.5 day, upper respiratory tract infection 58 examples wherein, bronchitis 78 examples are with heating 44 examples.
Two, diagnostic criteria: all meet following clinical symptoms all be diagnosed as the respiratory tract bronchitis disease.
(1) cough, expectoration or companion pant, annual morbidity 3 months, continuous 2 years or above person.
(2) annual morbidity less than is 3 months, and has clear and definite objective determination also diagnosable according to (as X line, determination of respiratory function etc.) person.
(3) can get rid of other hearts, lung disease (as pulmonary tuberculosis, asthma, bronchiectasis, pulmonary carcinoma, heart disease etc.) person.
Three, curative effect judging standard
Recovery from illness: body temperature is normal, the complete obiteration of respiratory tract infection sings and symptoms;
Effectively: body temperature is normal substantially, and sings and symptoms partly disappears or alleviates;
Invalid: sings and symptoms does not slow and separates or increase the weight of.
Four, Therapeutic Method: according to patient's hobby the present invention is made oral liquid, powder or pill and take 15 grams every day, divide and take for three times.7 days is a course of treatment.
Five, therapeutic outcome is summed up
After treating 1 course of treatment, 121 example recoveries from illness among the 136 routine patients, 10 examples are effective, and 5 examples are invalid, total effective rate 96.2%, it is 2～5 days that heating returns to normal time, does not find tangible untoward reaction.
Six. discuss
Tracheitis refers to the chronic nonspecific inflammation of trachea, bronchial mucosa and surrounding tissue thereof.Clinically with long-term cough, expectoration or with pant and repeatedly outbreak be feature.Chronic cough, expectoration or with panting, annual outbreak continues 3 months, continuous 2 years or more than, and can get rid of the heart, other illness of lung and outbreak repeatedly, part patient can develop into obstructive emphysema, chronic pulmonary heart disease.
Main cause has formed bronchial chronic nonspecific inflammation for the repeated infection of virus and antibacterial.When there's a sudden fall in temperature, degradation is beneficial to pathogenic under the respiratory tract small blood vessel spasm ischemia, defense function; Chronic stimulations such as smog dust, atmosphere pollution also can be fallen ill; Smoking makes bronchospasm, mucosa variation, ciliary movement reduction, mucous secretion increase favourable infection; Irritated factor also has certain relation.The antibiotic treatment usually of many at present employings.
Employing is taken the effect that preparation of the present invention treats and is shown it and adopt the antibiotics effect similar, but its both do not had antibiotics common anaphylaxis, the also situation of outbreak repeatedly not substantially, its effect is better than adopting merely antibiotic therapy.
Seven, model case
Example 1: Hu, man, 14 years old.After 6 years causes are suffered from the right side lobar pneumonia, every because of climate change, suffer from cold, the burst cough with asthma, the Winter-Spring more so, during acute attack, be obvious expiratory dyspnea, cyanosis, can not put down night for sleeping in, need the oxygen supply of being in hospital, injection aminophylline, epinephrine or instillation adrenocortical hormone, the state of an illness can be alleviated.Over nearly 2 years, characteristic of disease increases the weight of, and it is increased to show effect, and often is in hospital, and can not adhere to study.Be diagnosed as the bronchus cough with asthma.Take the present invention after 5 days symptom begin to alleviate, treatment finishes back symptom basic controlling.Cold season at a time when finishing the course of treatment, this infant not only adheres to going to school, and can participate in the big physical trainings of activity such as playing ball, play ice, long-distance running.
Example 2: permitted certain, woman, 51 years old.Whitish yellow sputum is told in cough companion asthma 5 years, three season of spring autumn and winter cough with asthma do not heal, slightly alleviate summer.Once use therapy of combining Chinese and Western medicine, all do not obtain promising result.In recent years, symptom increases the weight of day by day, and often because of cough influence sleep, body constitution weakness is day by day become thin, and calls oneself the little joint swelling and pain of extremity.Check: grow, nutrition is relatively poor, pale complexion, two lung audibles and be dispersed in dried moist rale, the swelling of both hands articulations digitorum manus, dysfunction is diagnosed as asthmatic bronchitis, rheumatoid arthritis.Through with the present invention after 7 days, cough with asthma alleviates, and amount of expectoration reduces, and the course of treatment is when finishing, symptom and pulmonary's sign complete obiteration, and extremity size joint does not have conscious pain, and the swelling of both hands articulations digitorum manus obviously alleviates, and activity is freely more preceding.
Adopt the present invention to treat tonsillitis 263 clinical datas:
1, physical data: the patient that will be diagnosed as chronic tonsillitis is divided into treatment by randomly assigne and organizes 263 examples (male 128 examples, women 135 examples); Matched group 162 (male 80 examples, women 82 examples) example.Age 8-60 year, wherein natural situation distributes and sees Table one;
Table one chronic tonsillitis object of observation nature situation
Group N 8-12 year 13-20 year 21-30 year 30-40 year 41-60 mean age in year (year) average course of disease (year)
Treatment organizes 206 46 83 39 26 12 21.7 3.4
Matched group 162 14 48 55 35 10 23.8 4.6
Two groups of cases all meet diagnostics's standard of the chronic tonsillitis in " otolaryngologic diagnostics ".
2, indication: all chronic tonsillitiss have been when inflammation has been the irreversibility pathological changes due to the acute attack repeatedly, or the tonsil hypertrophy, hinder and breathe and the function of deglutition person, are diagnosis and treatment indication.
3, efficacy assessment standard:
Tonsillitis: no longer recur and tonsil comes off normally with inflammation, breathe and function of deglutition recovers normally as the recovery from illness standard.Produce effects: above-mentioned inflammation attack times obviously reduces, and tonsil obviously comes off and dwindles.Invalid: the equal no change of symptom and sign.
4, Therapeutic Method:
According to patient's hobby the present invention is made oral liquid, powder or pill and take 15 grams every day, divide and take for three times.The treatment of matched group injection penicillin.The treatment group 10 days was a course of treatment.
5, therapeutic outcome:
Two groups of clinical indices contrasts of chronic tonsillitis before the treatment
Group antiadoncus acute attack number of times
Treatment group 2.11 ± 0.52 6.25 ± 1.15
Matched group 2.08 ± 0.49 6.31 ± 1.26
P value＞0.05
By table as seen, the group difference P of every observation index of treatment group and matched group all＞0.05 (is the t check) before the treatment, illustrate that treatment group and the corresponding matched group light and heavy degree of every index before treatment is close, it is basic identical also to disclose the preceding lesion degree of its treatment, thereby certain comparability is arranged.
The Therapeutic Method of 6, discussion, chronic tonsillitis is a lot, and routine gives antibiotic and antipyretic analgesic, though can better control each acute attack, can not effect a radical cure primary disease.Surgical removal determined curative effect, but misery is bigger, and complication such as hemorrhage, infection easily takes place, needing hospitalization, expense is higher.The laser therapy tonsillitis has certain curative effect, but the bad control of the degree of depth, and easily causes massive hemorrhage, and clinician's operating difficulties etc. are former thereby can not get applying.Adopt Chinese medicine preparation treatment tonsillitis short treating period of the present invention, effect is better.
Claims (2)
1, a kind of treatment bronchitis and tonsillitic Chinese medicine preparation is characterized in that being made by the raw material of Chinese medicine of following weight parts:
Radix Polygalae 12-18, Radix Asteris 12-18, Radix Stemonae 12-18, Radix Platycodonis 8-12, Flos Farfarae 12-18, Herba Ephedrae (processed) 7-11, Semen Armeniacae Amarum 8-12, Radix Glycyrrhizae 7-11, Herba Houttuyniae 12-18, Semen Lepidii (Semen Descurainiae) 8-12, Fructus Perillae 8-12, Radix Peucedani 8-12, Flos Lonicerae 12-18, Fructus Forsythiae 12-18, Radix Scutellariae 9-15, Pericarpium Citri Reticulatae 10-15, Fructus Arctii 10-15, Radix Glehniae 10-15, Herba Asari 3-7, Rhizoma Zingiberis 4-8, Poria 12-18.
2, described treatment bronchitis of local exchange claim 1 and tonsillitic Chinese medicine preparation is characterized in that being made by the raw material of Chinese medicine of following weight parts:
Radix Polygalae 15, Radix Asteris 15, the Radix Stemonae 15, Radix Platycodonis 10, Flos Farfarae 15, Herba Ephedrae (processed) 9, Semen Armeniacae Amarum 10, Radix Glycyrrhizae 9, Herba Houttuyniae 15, Semen Lepidii (Semen Descurainiae) 10, Fructus Perillae 10, Radix Peucedani 10, Flos Lonicerae 15, Fructus Forsythiae 15, Radix Scutellariae 12, Pericarpium Citri Reticulatae 13, Fructus Arctii 13, Radix Glehniae 13, Herba Asari 5, Rhizoma Zingiberis 6, Poria 15.
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