CN101474377B - Chinese medicine prescription for treating chronic bronchitis - Google Patents

Chinese medicine prescription for treating chronic bronchitis Download PDF

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CN101474377B
CN101474377B CN2009100136778A CN200910013677A CN101474377B CN 101474377 B CN101474377 B CN 101474377B CN 2009100136778 A CN2009100136778 A CN 2009100136778A CN 200910013677 A CN200910013677 A CN 200910013677A CN 101474377 B CN101474377 B CN 101474377B
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prescription
chronic bronchitis
chinese medicine
radix
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CN101474377A (en
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张改英
史淼
朱长征
王秀荣
郝芳
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Abstract

The invention discloses a traditional Chinese medicine prescription for treating chronic bronchitis, which comprises the following components by weight part: 10 to 15 parts of honeysuckle flower, 10 to 15 parts of forsythia, 5 to 10 parts of platycodon root, 5 to 10 parts of radix stemonae, 10 to 15 parts of aster, 10 to 15 parts of cortex mori radicis, 5 to 10 parts of snakegourd fruit, 8 to 15 parts of cordate houttuynia, 8 to 10 parts of dried orange peel, 6 to 8 parts of pinellia tuber, and 10 to 12 parts of licorice. A drug of the prescription takes 7 to 10 days as a treatment course, has effect in 1 to 3 days, and heals up after 3 to 4 treatment courses. The prescription is a pure natural traditional Chinese medicine, and has the advantages of little toxic side effects and unique therapeutic effect; and through 3,100 cases of clinical application verification of patients, the total curative effect is as high as 98 percent. The prescription has the following advantages: 1, the prescription is a pure traditional Chinese medicine preparation which is convenient to use and has no obvious toxic side effects; 2, the prescription takes effect quickly and has definite curative effect; and 3, the prescription has excellent curative effect and low complication incidence rate, treats both symptoms and root causes, and has good long-term effect.

Description

A kind of Chinese medicinal formulae for the treatment of chronic bronchitis
Technical field
The present invention relates to a kind of Chinese medicinal formulae for the treatment of chronic bronchitis.
Background technology
Chronic bronchitis is because physics, chemical factor cause that trachea, bronchial mucosa inflammatory change, mucus secretion increasing, clinical appearance cough, expectoration and symptom such as out of breath.Early symptom is slight, and how in the winter time outbreak is alleviated after the spring is warm, and late period, inflammation increased the weight of, and symptom exists throughout the year, is regardless of season; Progression of disease again can concurrent emphysema, pulmonary hypertension and hypertrophy of right heart, have a strong impact on the healthy of people.
The cause of disease of chronic bronchitis and pathogeny: the pathogenic factor of primary disease is unclear fully, it is generally acknowledged the reason that following two aspects can be arranged:
Exopathogenic factor: one, the domestic and international research of smoking proves that all smoking and chronic bronchitis have substantial connection, and the smoking time is long more, and smoking capacity is big more, and prevalence is high more.Can make sx or disappearance after the smoking cessation.
Two, the infective agent infection is the key factor of chronic bronchitis.Mainly be virus and bacterial infection.
Three, chemical factors such as irritating smog, dust, atmospheric pollution often are one of risk factor of chronic bronchitis.
Four, weather is cold is the major reason and the risk factor of chronic bronchitis often.The chronic bronchitis morbidity is everlasting cold season in winter, when especially weather changes suddenly, cold air stimulation respiratory tract, except that the defensive enginery that weakens the upper respiratory tract mucosa, can also cause that bronchial smooth muscle shrinks by reflection, mucosa disturbance of blood circulation and secretions are got rid of difficulty etc., help secondary infection.
Five, irritated factor asthmatic bronchitis often has allergies.
Endogenous cause of ill: one, the attenuating normal person respiratory tract of respiratory tract local defense and immunologic function has complete defense function, to inhaled air filter, heat, moistening.The mucosa ciliary movement of bronchial mucosa and coughre flex all can purify and get rid of foreign body and too much secretions, go back immunoglobulin,exocrine in bronchioles and the alveolar, and the effect of antiviral and antibacterial is arranged.When whole body and respiratory tract local defense and immunologic hypofunction, can be chronic bronchitis onset condition is provided.
Two, autonomic nervous dysfunction can cause the bronchoconstriction spasm when respiratory tract parasympathetic increased response, secretions increase, and produce cough, expectoration, asthma.
The clinical manifestation of chronic bronchitis: part patient has acute respiratory infection histories such as acute bronchitis, influenza or pneumonia before onset.Be everlasting cold season morbidity of patient cough occurs, coughs up phlegm, and is work, the expectorant mucus spume shape that is white in color to rise morning especially, and thickness is difficult for expectoration.When acute respiratory infection, symptom is aggravated rapidly.Amount of expectoration increases, and viscosity increases or is yellow purulence, and idol has sputum mixed with blood.After chronic bronchitis was shown effect repeatedly, the vagus nerve sensor reactivity of bronchial mucosa increased, and parasympathetic functions is hyperfunction, can allergic phenomena occur and panted.Along with PD, cough all the year round, expectoration does not stop, the aggravation of autumn in winter.The asthmatic bronchitis patient often has the outbreak of asthma sample when symptom aggravation or secondary infection, out of breath can not put down for sleeping in.Dyspnea is generally not obvious, but after the concurrent emphysema, along with the emphysema degree increases, then dyspnea exacerbates gradually.
The clinical diagnosis of chronic bronchitis: chronic bronchitis does not have any unusual sign in early days, and dried, the moist rale that are dispersed in can be arranged during acute attack.The chronic asthmatic bronchitis stage of attack,, pulmonary can hear wheezing sound and prolonged expiration, and as when infecting, rale increases.The X ray examination, increases visible increased bronchovascular shadows, based in two, march off into political wilderness.Lung marking disorder during secondary infection, thick Unfeigned or have little patch to strengthen shade.
The treatment of chronic bronchitis: one, the treatment of acute stage mainly be control infection, eliminate the phlegm, antitussive, releasing spasm, aerosol therapy.
Two, paracmastic treatment: give up smoking, strengthen physical training, rationally regulate indoor temperature, eat the food that contains vitamin more.Improve the resistance against diseases of body.
At present,, also there is the medicine of multiple treatment chronic bronchitis in the prior art, exists therapeutic effect undesirable mostly, can not effect a radical cure shortcomings such as therapeutic process complexity, cost height though domestic expert's therapeutic scheme is more.
Summary of the invention
At above-mentioned the deficiencies in the prior art, the invention provides a kind of Chinese medicinal formulae for the treatment of chronic bronchitis.
A kind of Chinese medicinal formulae for the treatment of chronic bronchitis is characterized in that, is made up of the component of following weight portion: 10~15 parts of Flos Loniceraes, 10~15 parts of Fructus Forsythiaes, 5~10 parts of Radix Platycodoniss, 5~10 parts of the Radixs Stemonae, 10~15 parts of Radix Asteriss, 10~15 parts of Cortex Mori, 5~10 parts of Fructus Trichosanthis, 8~15 parts of Herba Houttuyniae, 8~10 parts of Pericarpium Citri Reticulataes, 6~8 parts of the Rhizoma Pinelliaes, 10~12 parts in Radix Glycyrrhizae.
The umber of described each component is: 15 parts of Flos Loniceraes, 10 parts of Fructus Forsythiaes, 10 parts of Radix Platycodoniss, 10 parts of the Radixs Stemonae, 10 parts of Radix Asteriss, 10 parts of Cortex Mori, 10 parts of Fructus Trichosanthis, 15 parts of Herba Houttuyniae, 10 parts of Pericarpium Citri Reticulataes, 6 parts of the Rhizoma Pinelliaes, 10 parts in Radix Glycyrrhizae.
The umber of described each component is: 10 parts of Flos Loniceraes, 10 parts of Fructus Forsythiaes, 5 parts of Radix Platycodoniss, 5 parts of the Radixs Stemonae, 10 parts of Radix Asteriss, 10 parts of Cortex Mori, 5 parts of Fructus Trichosanthis, 8 parts of Herba Houttuyniae, 8 parts of Pericarpium Citri Reticulataes, 6 parts of the Rhizoma Pinelliaes, 10 parts in Radix Glycyrrhizae.
The umber of described each component is: 12 parts of Flos Loniceraes, 11 parts of Fructus Forsythiaes, 8 parts of Radix Platycodoniss, 8 parts of the Radixs Stemonae, 12 parts of Radix Asteriss, 13 parts of Cortex Mori, 8 parts of Fructus Trichosanthis, 11 parts of Herba Houttuyniae, 9 parts of Pericarpium Citri Reticulataes, 8 parts of the Rhizoma Pinelliaes, 11 parts in Radix Glycyrrhizae.
The dosage form of described Chinese medicinal formulae is any in tablet, powder, the capsule.
The preparation method of described Chinese medicinal formulae is an example with the capsule, got each component by weight after, dried porphyrize powder is crossed 300 mesh sieves, No. 1 capsule of packing into gets final product.
Usage and consumption: oral, every day three times, each two, 7~10 days courses of treatment.
Side effect and contraindication: the clinical observation on the therapeutic effect through 20 years, patient does not have obvious toxic-side effects and takes place; Anemia of pregnant woman and allergic constitution patient forbidding.
According to China's traditional medical theory and modern medicine viewpoint, the pharmacological action of each medicine and compatibility characteristics are summarized as follows:
Flos Lonicerae: detoxifcation is loose bitterly, and clearing away heat and cooling blood, modern medicine study prove that this medical instrument has antibiotic widely, antivirus action, and the energy raise immunity, promotes lymphocyte transformation, strengthens leukocytic phagocytic function.
Fructus Forsythiae: heat-clearing and toxic substances removing, dispelling wind and heat pathogens has the effect of broad-spectrum disease resistance pathogenic microorganism, antiinflammatory, analgesic, town's Tuhe diuresis
Radix Platycodonis: preventing phlegm from forming and stopping coughing, lung qi dispersing sore-throat relieving.Especially has the wide range of therapeutic effect at aspects such as immunomodulating, antiinflammatory eliminate the phlegm.
The Radix Stemonae: cough-relieving, relieving asthma.Control cough, abundant expectoration, QI rising in reverse order.
Radix Asteris: nourishing the lung to keep the adverse QI downward, stopping coughing and removing phlegm.Suitable especially to the abundant expectoration cough with asthma, according to relevant this medical instrument of research card stronger relieving cough and expelling phlegm and antibacterial action are arranged.
Cortex Mori: lung qi dispersing heat clearing away, relieving cough and resolving phlegm, lowering the adverse-rising QI to subdue asthma.Be applicable to diseases caused by exogenous pathogenic factor or internal injury caused cough gargle, pant, disease such as abundant expectoration.
Fructus Trichosanthis: removing heat-phlegm, lung moistening eliminating stagnation.Experiment showed, Fructus Trichosanthis to staphylococcus, Diplococcus pneumoniae, hemophilus influenza all have inhibitory action.
Herba Houttuyniae: heat-clearing and toxic substances removing, the pain that disappears evacuation of pus is used for the expectorant dyspnea of heat type especially and coughs, the pain in the lung vomiting pus.
Pericarpium Citri Reticulatae: in the accent of regulating the flow of vital energy, drying dampness to eliminate phlegm, but the intestinal pneumatosis is got rid of in the secretion of facilitating digestion liquid.Contained volatile oil has phlegm-dispelling functions, also can make bronchiectasis, reaches the effect of relievining asthma.
The Rhizoma Pinelliae: drying dampness to eliminate phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, dissolving lump and resolving mass.Especially with Pericarpium Citri Reticulatae Fructus Trichosanthis mutually 5, diseases such as treatment phlegm dampness obstruction pattern, cough with asthma QI rising in reverse order.
Radix Glycyrrhizae: spleen reinforcing, lung moistening, detoxifcation, coordinating the actions of various ingredients in a prescription.Available again its of one desirable nourishing the lung to arrest cough effect slows down the bias and the toxicity of other drug.
The treatment theory of the traditional Chinese medical science is thought: chronic bronchitis is dialectical, and to focus on lung, spleen, kidney three dirty, the spleen by lung and kidney, and the expression state of an illness increases the weight of gradually.The lung being the dominator of QI is the device of storage expectorant, and lung loses and controls joint, at lung then based on cough; The spleen being the source of producing phlegm is main for coughing up phlegm then at spleen; The kidney being the root of QI, give birth to expectorant this, at kidney based on asthma.Lung is not hindered and is not coughed, and spleen is not hindered not chronic cough, and kidney is not hindered not dyspnea with rapid and short breath.Primary disease is marked on lung, and built in spleen, this is at kidney.Chronic bronchitis is divided into excess syndrome, deficiency syndrome two big classes according to its clinical manifestation more.Chronic bronchitis is prolonged illness, and prolonged illness must be empty, so the essence of the primary disease deficiency and coldness that belong to more.Be reflected in the dirty void of lung, spleen, kidney three, be more common in the clinical relieving period of chronic bronchitis.If the upper respiratory tract repeated infection, state of an illness aggravation then goes out reality, heat, expectorant, wet syndrome, forms the weakened body resistance complex situations of the domination of pathogen.Be mainly seen in acute episode of chronic bronchitis phase and chronic persistence.Excess syndrome acute episode of chronic bronchitis phase and chronic persistence, deficiency syndrome chronic bronchitis clinical relieving period.
Prescription of the present invention is according to China's theory of TCM, in conjunction with inventor's clinical research for many years, and use the modern medicine technology character of chronic bronchitis is diagnosed, the combination of Chinese and Western medicine, in the process of clinical treatment, given prominence to the characteristics of theory of Chinese medical science in therapeutic process, 7~10 days is a course of treatment, 1~3 day takes effect, and gets final product rehabilitation 3~4 courses of treatment.This prescription is a natural Chinese medicines, and it is little to have toxic and side effects, the advantage of therapeutical effect uniqueness, and through clinical 3100 routine patients' application verification, total effective rate is up to 98%.
The present invention has the following advantages: 1, pure Chinese medicinal preparation, and easy to use, no obvious toxic-side effects.2, instant effect, determined curative effect.3, effective percentage height, complication rate is little, treating both the principal and secondary aspects of a disease, long-term effect is good.
The specific embodiment
The present invention is further illustrated below in conjunction with embodiment, clinical data and case:
Embodiment 1: prepare a kind of Chinese medicinal formulae for the treatment of chronic bronchitis: get Flos Lonicerae 15 grams, Fructus Forsythiae 10 grams, Radix Platycodonis 10 grams, the Radix Stemonae 10 grams, Radix Asteris 10 grams, Cortex Mori 10 grams, Fructus Trichosanthis 10 grams, Herba Houttuyniae 15 grams, Pericarpium Citri Reticulatae 10 grams, the Rhizoma Pinelliae 6 grams, Radix Glycyrrhizae 10 grams, dried porphyrize powder is crossed 300 mesh sieves, and No. 1 capsule of packing into gets final product.
Embodiment 2: prepare a kind of Chinese medicinal formulae for the treatment of chronic bronchitis: get Flos Lonicerae 10 grams, Fructus Forsythiae 10 grams, Radix Platycodonis 5 grams, the Radix Stemonae 5 grams, Radix Asteris 10 grams, Cortex Mori 10 grams, Fructus Trichosanthis 5 grams, Herba Houttuyniae 8 grams, Pericarpium Citri Reticulatae 8 grams, the Rhizoma Pinelliae 6 grams, Radix Glycyrrhizae 10 grams, dried porphyrize powder is crossed 300 mesh sieves, and No. 1 capsule of packing into gets final product.
Embodiment 3: prepare a kind of Chinese medicinal formulae for the treatment of chronic bronchitis: get Flos Lonicerae 12 grams, Fructus Forsythiae 11 grams, Radix Platycodonis 8 grams, the Radix Stemonae 8 grams, Radix Asteris 12 grams, Cortex Mori 13 grams, Fructus Trichosanthis 8 grams, Herba Houttuyniae 11 grams, Pericarpium Citri Reticulatae 9 grams, the Rhizoma Pinelliae 8 grams, Radix Glycyrrhizae 11 grams, dried porphyrize powder is crossed 300 mesh sieves, and No. 1 capsule of packing into gets final product.
Embodiment 4: prepare a kind of Chinese medicinal formulae for the treatment of chronic bronchitis: get Flos Lonicerae 15 grams, Fructus Forsythiae 15 grams, Radix Platycodonis 10 grams, the Radix Stemonae 10 grams, Radix Asteris 15 grams, Cortex Mori 15 grams, Fructus Trichosanthis 10 grams, Herba Houttuyniae 15 grams, Pericarpium Citri Reticulatae 10 grams, the Rhizoma Pinelliae 8 grams, Radix Glycyrrhizae 12 grams, dried porphyrize powder is crossed 300 mesh sieves, and No. 1 capsule of packing into gets final product.
Embodiment 5: prepare a kind of Chinese medicinal formulae for the treatment of chronic bronchitis: get Flos Lonicerae 14 grams, Fructus Forsythiae 14 grams, Radix Platycodonis 6 grams, the Radix Stemonae 6 grams, Radix Asteris 13 grams, Cortex Mori 11 grams, Fructus Trichosanthis 6 grams, Herba Houttuyniae 13 grams, Pericarpium Citri Reticulatae 9 grams, the Rhizoma Pinelliae 7 grams, Radix Glycyrrhizae 11 grams, dried porphyrize powder is crossed 300 mesh sieves, and No. 1 capsule of packing into gets final product.
Clinical data:
1, data:
The case data selects have complete outpatient service data and inpatient 5960 examples year October in November, 2004-2008, is divided into treatment at random and organizes 3100 examples, matched group 2860 examples.The treatment group age is at 32~80 years old, the course of disease 1~10 year.The matched group age is at 33~79 years old, the course of disease 2~11 years.Men and women's the ratio and the course of disease are through X 2 test (P>0.05) not statistically significant.
2, Therapeutic Method: the treatment group is divided oral meal every day 3 times with prescription capsule of the present invention, and each 2,7 days is a course of treatment.The oral Roxithromycin 0.3g/d of matched group, divide 2 times oral, mucosolvan 30mg, every day 3 times is oral.
3, statistical method: two groups clinical uses X 2 test, between two groups relatively, the RIDUT check, the cure rate of treatment group as a result is apparently higher than matched group, relatively there were significant differences between total effective rate group property P<0.001.(seeing Table 1)
Table 1. liang group cure rate synopsis
Figure G2009100136778D00051
Annotate: P<0.001
4, side effect and contraindication:
Side effect: the clinical observation on the therapeutic effect through 20 years, patient does not have obvious toxic-side effects and takes place.
Contraindication: anemia of pregnant woman and allergic constitution patient forbidding.
Case 1: Liu, the woman, 55 years old, the patient was because of coughing, coughing up phlegm for two weeks, and the expectorant character is difficult for expectoration for sticking turbid expectorant.Red tongue yellow fur, stringy and rolling pulse number.Heating, the pus tears, pharyngalgia, thirsty, yellowish urine, dry stool.Base of lung portion can hear rhonchi.The X ray examination sees that two lung bottom textures increase slightly, be the rope strip, be diagnosed as acute episode of chronic bronchitis, give and antibiotic and resolving phlegm and relieving asthma treatment, the two all therapeutic effect of being in hospital are not good enough, after use antibiotic instead and take capsule of the present invention after 5 days, symptom is controlled, take 2 courses of treatment after, the symptom complete obiteration, be discharged from hospitals upon recovery,, do not have recurrence with examining 1.5 years.
Case 2: Chen, the woman, 65 years old, the patient was because of suffering from chronic bronchitis 10 years, and increase the weight of annual winter, and its symptom is to breathe hard after the activity to be feature.Sick send out that to cough loud, high-pitched sound often puckery, mostly be apasm of coughing, night, amount of expectoration was many more than day.Pale tongue is fat or have the stasis of blood to resemble, white and slippery fur profit, deep-thready pulse.Examined and be chronic bronchitis.Take capsule of the present invention, remission after 7 days, transference cure after 20 days continues to take and consolidated curative effect in 2 months, does not have recurrence in 2 years with examining.
Case 3: Jiang, the man, 45 years old, the patient was because of cough all the year round, and expectoration does not stop, the aggravation of autumn in winter.Meet cold back failing to lie flat due to dyspnea.Heavy cough is coughed repeatedly, and heavy day of night is light, coughs sputum crudum.Amount of expectoration is more.Pale tongue or fat has indentation, and tongue fur is white or white thick greasy.Relaxed and soft pulse or cunning.Inappetence, abdominal distention after meal, the face edema due to deficiency, big loose stool is soft.The X ray examination sees that two lung bottom textures increase slightly, in cough or dark can hear the asthma sound after air-breathing, is diagnosed as asthmatic bronchitis and takes capsule of the present invention, the remission of panting after 5 days, symptom complete obiteration after 20 days continues to take and consolidates curative effect 3 courses of treatment, with examining not recurrence in 2 years.
Case 4, Wang, the man, 76 years old, the patient because of cough, coughed up phlegm 10 years, increase the weight of winter, cough is work, the expectorant mucus spume shape that is white in color to rise morning especially, thickness is difficult for expectoration.The X ray examination is seen in two lungs, the bottom texture increases slightly, and base of lung portion can hear rhonchi, is diagnosed as chronic bronchitis, takes capsule of the present invention, remission after 15 days, and transference cure after 20 days continues to take and consolidated curative effect in 40 days, does not have recurrence with examining 1.5 years patients.。
Case 5, Guo so-and-so, the woman, 85 years old, the patient because of the repeated relapsing cough, coughed up phlegm 15 years, the expelling phlegm drugs treatment of relievining asthma is taken in winter and flu postemphasis throughout the year, effect is not good enough.After taking capsule for treating of the present invention, remission after 10 days, transference cure after 20 days is consolidated curative effect 3 courses of treatment of continuing to take medicine, and does not have recurrence in 1 year with examining.

Claims (5)

1. a Chinese medicine preparation for the treatment of chronic bronchitis is characterized in that, its crude drug consists of: 10~15 parts of Flos Loniceraes, 10~15 parts of Fructus Forsythiaes, 5~10 parts of Radix Platycodoniss, 5~10 parts of the Radixs Stemonae, 10~15 parts of Radix Asteriss, 10~15 parts of Cortex Mori, 5~10 parts of Fructus Trichosanthis, 8~15 parts of Herba Houttuyniae, 8~10 parts of Pericarpium Citri Reticulataes, 6~8 parts of the Rhizoma Pinelliaes, 10~12 parts in Radix Glycyrrhizae, by weight.
2. a kind of Chinese medicine preparation for the treatment of chronic bronchitis according to claim 1 is characterized in that its crude drug consists of: 15 parts of Flos Loniceraes, 10 parts of Fructus Forsythiaes, 10 parts of Radix Platycodoniss, 10 parts of the Radixs Stemonae, 10 parts of Radix Asteriss, 10 parts of Cortex Mori, 10 parts of Fructus Trichosanthis, 15 parts of Herba Houttuyniae, 10 parts of Pericarpium Citri Reticulataes, 6 parts of the Rhizoma Pinelliaes, 10 parts in Radix Glycyrrhizae.
3. a kind of Chinese medicine preparation for the treatment of chronic bronchitis according to claim 1 is characterized in that its crude drug consists of: 10 parts of Flos Loniceraes, 10 parts of Fructus Forsythiaes, 5 parts of Radix Platycodoniss, 5 parts of the Radixs Stemonae, 10 parts of Radix Asteriss, 10 parts of Cortex Mori, 5 parts of Fructus Trichosanthis, 8 parts of Herba Houttuyniae, 8 parts of Pericarpium Citri Reticulataes, 6 parts of the Rhizoma Pinelliaes, 10 parts in Radix Glycyrrhizae.
4. a kind of Chinese medicine preparation for the treatment of chronic bronchitis according to claim 1 is characterized in that its crude drug consists of: 12 parts of Flos Loniceraes, 11 parts of Fructus Forsythiaes, 8 parts of Radix Platycodoniss, 8 parts of the Radixs Stemonae, 12 parts of Radix Asteriss, 13 parts of Cortex Mori, 8 parts of Fructus Trichosanthis, 11 parts of Herba Houttuyniae, 9 parts of Pericarpium Citri Reticulataes, 8 parts of the Rhizoma Pinelliaes, 11 parts in Radix Glycyrrhizae.
5. a kind of Chinese medicine preparation for the treatment of chronic bronchitis according to claim 1 is characterized in that: the dosage form of described Chinese medicine preparation is any in tablet, powder, the capsule.
CN2009100136778A 2009-01-23 2009-01-23 Chinese medicine prescription for treating chronic bronchitis Expired - Fee Related CN101474377B (en)

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CN104906434A (en) * 2015-07-01 2015-09-16 王艳红 Cough expelling and phlegm reduction drink for treating chronic bronchitis and preparation method of cough expelling and phlegm reduction drink
CN105816778A (en) * 2016-05-10 2016-08-03 刘建波 Traditional Chinese medicine oral solution for treating chromic bronchitis
CN107715023A (en) * 2017-11-07 2018-02-23 单县领翔金银花种植合作社 One kind treats the elderly's bronchitis medicine and preparation method thereof

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