CN1686423A - 一种含有黄芩苷和柴胡的药物组合物及其制备方法 - Google Patents
一种含有黄芩苷和柴胡的药物组合物及其制备方法 Download PDFInfo
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- CN1686423A CN1686423A CN 200510067854 CN200510067854A CN1686423A CN 1686423 A CN1686423 A CN 1686423A CN 200510067854 CN200510067854 CN 200510067854 CN 200510067854 A CN200510067854 A CN 200510067854A CN 1686423 A CN1686423 A CN 1686423A
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- Medicinal Preparation (AREA)
Abstract
Description
中心0102030405合计 | 入组病例数 | 脱落病例数 | 剔除病例数 | 完成病例数 | ||||||||||||
A组 | B组 | C组 | 合计 | A组 | B组 | C组 | 合计 | A组 | B组 | C组 | 合计 | A组 | B组 | C组 | 合计 | |
2424242424120 | 2424242424120 | 2424242424120 | 7272727272360 | 030003 | 150028 | 140027 | 21200418 | 100001 | 200002 | 000000 | 300003 | 2321242424116 | 2119242422110 | 2320242422113 | 6760727268339 |
中心 | 符合方案集 | 意向性分析集 | 安全集 | |||||||||
A组 | B组 | C组 | 合计 | A组 | B组 | C组 | 合计 | A组 | B组 | C组 | 合计 | |
0102030405 | 2321242424 | 2149242422 | 2320242422 | 6760727268 | 2322242424 | 2221242422 | 2320242422 | 6863727268 | 2424242424 | 2424242424 | 2424242424 | 7272727272 |
合计 | 116 | 110 | 113 | 339 | 117 | 113 | 113 | 343 | 120 | 120 | 120 | 360 |
组别 | n | 痊愈 | 显效 | 有效 | 无效 | 总显效率 | 总有效率 | ||||
n | % | n | % | n | % | n | % | ||||
A组B组C组 | 116110113 | 504629 | 43.1041.8225.66 | 505053 | 43.1045.4546.90 | 131130 | 11.2110.0026.55 | 331 | 2.592.730.88 | 86.2087.2772.59 | 97.4197.2799.12 |
组别 | n | 痊愈 | 显效 | 有效 | 无效 | 总显效率 | 总有效率 | ||||
N | % | n | % | n | % | n | % | ||||
A组 | 116 | 50 | 46.55 | 50 | 43.10 | 9 | 7.76 | 3 | 2.59 | 89.65 | 97.41 |
B组C组 | 110113 | 4829 | 43.6425.66 | 4653 | 41.8246.90 | 1330 | 11.0026.55 | 31 | 2.730.88 | 85.4672.59 | 97.2799.12 |
组别 | n | 治疗前x±S | 治疗后x±S | 差值x±S | F | P |
A组B组C组 | 116110113 | 37.85±0.4137.88±0.3837.95±0.43 | 36.82±0.4236.84±0.3536.89±0.48 | 1.031±0.4321.050±0.4241.028±0.398 | 0.09 | 0.915 |
症状发热微恶寒咽痛 | 组别A组B组C组A组B组C组 | n116110113116110113 | 治前 | 治中 | 治后 | |||||||||
无000000 | 轻483642695459 | 中525749374144 | 重161722101510 | 无695861182117 | 轻384338917280 | 中991371714 | 重001002 | 无10810193817359 | 轻5518343749 | 中341104 | 重001001 |
组别 | n | 治前 | 治后 | 组内 | 组间 | |||
正常 | 红 | 正常 | 红 | P* | X2 | P | ||
A组B组C组 | 116110113 | 444 | 112106109 | 827666 | 343447 | 0.000.000.00 | 4.512 | 0.105 |
组别 | n | 治前 | 治后 | 组内 | 组间 | |||||
正常 | 簿黄 | 其他 | 正常 | 簿黄 | 其他 | P* | X2 | P |
A组B组C组 | 116110113 | 788 | 109102105 | 000 | 807775 | 363338 | 000 | 0.000.000.00 | 0.362 | 0.834 |
组别 | n | 治前 | 治后 | 组内 | 组间P* | |||
正常 | 浮数 | 正常 | 浮数 | X2 | P | |||
A组B组C组 | 116110113 | 343632 | 827481 | 11110595 | 5518 | 71.34 | 0.000.000.00 | 0.003 |
组别 | n | 治前 | 治后 | 组内 | 组间 | ||||
阴性(%) | 阳性(%) | 阴性(%) | 阳性(%) | Z | P | X2 | P | ||
A组B组C组 | 938994 | 65(69.89)59(66.29)64(68.82) | 28(30.11)30(23.71)29(68.82) | 89(95.70)86(96.63)86(31.18) | 4(4.30)3(3.37)8(7.53) | 4.8995.1964.690 | 0.000.000.00 | 1.807 | 0.405 |
组别 | n | ~12 | ~24 | ~48 | ~72 | 未起效 | X2 | P |
A组B组C组 | 116110113 | 838677 | 161318 | 9610 | 111 | 777 | 1.445 | 0.695 |
组别 | n | x±S | F | P |
A组B组C组 | 109105107 | 10.29±11.809.67±8.8011.73±13.32 | 0.90 | 0.41 |
组别 | n | ~12 | ~24 | ~48 | ~72 | 未起效 | X2 | P |
A组B组 | 116110 | 5337 | 2020 | 1522 | 714 | 2117 | 9.32 | 0.32 |
C组 | 113 | 44 | 19 | 16 | 8 | 26 |
组别 | n | x±S | F | P |
A组B组C组 | 1069590 | 25.59±27.9226.17±21.9821.97±20.72 | 0.84 | 0.43 |
Claims (14)
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CNB2005100678542A CN100512796C (zh) | 2005-04-28 | 2005-04-28 | 一种含有黄芩苷和柴胡的药物组合物及其制备方法 |
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CNB2005100678542A CN100512796C (zh) | 2005-04-28 | 2005-04-28 | 一种含有黄芩苷和柴胡的药物组合物及其制备方法 |
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CN1686423A true CN1686423A (zh) | 2005-10-26 |
CN100512796C CN100512796C (zh) | 2009-07-15 |
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Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN100420456C (zh) * | 2006-03-14 | 2008-09-24 | 北京国丹药物技术开发有限公司 | 复方柴胡灌肠液制剂及其制备方法 |
CN102641333A (zh) * | 2012-04-11 | 2012-08-22 | 河南灵佑药业有限公司 | 一种无糖型柴黄颗粒剂及其制备方法 |
CN102106884B (zh) * | 2009-12-25 | 2013-08-21 | 财团法人工业技术研究院 | 具有免疫调节功能的医药组合物 |
US8597693B2 (en) | 2010-07-01 | 2013-12-03 | Industrial Technology Research Institute | Pharmaceutical composition with immunomodulating function |
CN106309522A (zh) * | 2016-08-24 | 2017-01-11 | 扬子江药业集团上海海尼药业有限公司 | 柴芩清宁胶囊及其制备方法 |
-
2005
- 2005-04-28 CN CNB2005100678542A patent/CN100512796C/zh active Active
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN100420456C (zh) * | 2006-03-14 | 2008-09-24 | 北京国丹药物技术开发有限公司 | 复方柴胡灌肠液制剂及其制备方法 |
CN102106884B (zh) * | 2009-12-25 | 2013-08-21 | 财团法人工业技术研究院 | 具有免疫调节功能的医药组合物 |
US8597693B2 (en) | 2010-07-01 | 2013-12-03 | Industrial Technology Research Institute | Pharmaceutical composition with immunomodulating function |
CN102641333A (zh) * | 2012-04-11 | 2012-08-22 | 河南灵佑药业有限公司 | 一种无糖型柴黄颗粒剂及其制备方法 |
CN106309522A (zh) * | 2016-08-24 | 2017-01-11 | 扬子江药业集团上海海尼药业有限公司 | 柴芩清宁胶囊及其制备方法 |
CN106309522B (zh) * | 2016-08-24 | 2017-07-28 | 扬子江药业集团上海海尼药业有限公司 | 柴芩清宁胶囊及其制备方法 |
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