CN1520842A - Liposoluble suppository for treating prostatitis - Google Patents
Liposoluble suppository for treating prostatitis Download PDFInfo
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- CN1520842A CN1520842A CNA031028411A CN03102841A CN1520842A CN 1520842 A CN1520842 A CN 1520842A CN A031028411 A CNA031028411 A CN A031028411A CN 03102841 A CN03102841 A CN 03102841A CN 1520842 A CN1520842 A CN 1520842A
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Abstract
The rectum administrated liposoluble suppository for treating prostatitis and eliminating stranguria is prepared with fringed pink, knotgrass, manchurian dutchmanspipe stem, plantain seed, talcum, cape jasmine, rhubarb, licorice and semi-synthetic stearate. The suppository can act on prostate directly via rectum administration, has the functions of clearing away heat, purging intense heat, promoting diuresis and relieving straguria, and is used in treating prostatitis and it caused frequent micturition, dripping, urine retention, lower abdomen distention and other syndromes.
Description
Technical field: the present invention relates to the fat-soluble Chinese medicine suppository of the prostatitic rectally of a kind of treatment, drench suppository and preparation method thereof clearly.
Background technology: be used for clearing away heat-fire at present, relieving stranguria by diuresis, the puckery pain of frequent micturition that cures mainly prostatitis and cause, it is not smooth to drench drop, and the difficulty in urination is obstructed, the lower abdomen overflow, the pharmaceutical dosage form of diseases such as dry mouth and throat mainly contains tablet, capsule, granule etc.Be difficult for absorbing prostatic because of oral, can not fully absorb the drug, can not reach optimum therapeuticing effect.
Summary of the invention: the objective of the invention is to propose the prostatitic suppository of a kind of treatment, the clear suppository that drenches, thinking is with reference to former health kind promulgated by the ministries or commissions of the Central Government, the technical background that " drenches electuary clearly ", it has changed the oral route of administration of original treatment prostatitis, adopt the rectally mode, it has overcome the deficiency of oral administration mode.The present invention does not lie in pharmacological active substance itself and is to become other component of novel form, and its preparation method is provided simultaneously.Suppository of the present invention is made by the following weight proportion raw material: Herba Dianthi 440-460 part, holds 440-460 part, Caulis Aristolochiae Manshuriensis 440-460 part, Semen Plantaginis (salt stir-fry) 440-460 part, Talcum 440-460 part, Fructus Gardeniae 440-460 part, Radix Et Rhizoma Rhei 440-460 part, Radix Glycyrrhizae (processing) 440-460 part, decoct with water three times, each 1 hour, add for the first time 10 times of amounts of water, second, add 8 times of amounts of water for the third time, collecting decoction, filter, filtrate is concentrated into 1: 1.5, adds ethanol and makes and contain the alcohol amount and reach 65%, fully stir, placed 24 hours, and filtered, it is an amount of that precipitation adds 65% ethanol again, fully stir, placed 4 hours, and filtered, merge decompression recycling ethanol to relative density 1.18-1.20 with above-mentioned filtrate, spray drying, get fine powder and cross the 100-120 mesh sieve, get semi-synthetic fatty acid ester 380-400 part water-bath fusing by weight, add above-mentioned fine powder and stir, its medicated powder and substrate ratio are while hot to annotate film at 1: 1.4, promptly get after the cooled and solidified and treat prostatitic suppository.Technique effect of the present invention is, this suppository is according to traditional Chinese medical science traditional theory " medicine is smash disease institute ", change original oral administration route, be processed into, directly act on prostatic through science, the administration of suppository per anum, not only reducing medicine stimulates gastrointestinal, avoids a first pass effect of liver system, and directly acts on prostatic, absorb soon, therapeutic effect is better.
Embodiment 1: present embodiment is made by following materials of weight proportions: Herba Dianthi 450g, hold 450g, Semen Plantaginis (salt stir-fry) 450g, Talcum 450g, Fructus Gardeniae 450g, Radix Et Rhizoma Rhei 450g, Radix Glycyrrhizae (processing) 450g.With above eight flavors, decoct with water each 1 hour three times, add for the first time water 36000g, second, add water 28800g for the third time, collecting decoction, filter, filtrate is concentrated into 1: 1.5, adds ethanol and makes and contain the alcohol amount and reach 65%, fully stir, placed 24 hours, and filtered, it is an amount of that precipitation adds 65% ethanol again, fully stir, placed 4 hours, and filtered, merge with above-mentioned filtrate, decompression recycling ethanol also is concentrated into relative density 1.18～1.20, spray drying gets fine powder and crosses 100 mesh sieves, gets semi-synthetic fatty acid ester 390g water-bath fusing by weight, adding above-mentioned fine powder stirs, its medicated powder and semi-synthetic fatty acid ester, ratio are 1: 1.4, annotate film while hot, make 270 suppositorys after the cooled and solidified, every heavy 2.4g.
Embodiment 2: present embodiment is made by following materials of weight proportions: Herba Dianthi 460g, hold 460g, Semen Plantaginis (salt stir-fry) 460g, Talcum 460g, Fructus Gardeniae 460g, Radix Et Rhizoma Rhei 460g, Radix Glycyrrhizae (processing) 460g.With above eight flavors, decoct with water each 1 hour three times, add for the first time water 36800g, second, add water 29240g for the third time, collecting decoction, filter, filtrate is concentrated into 1: 1.5, adds ethanol and makes and contain the alcohol amount and reach 65%, fully stir, placed 24 hours, and filtered, it is an amount of that precipitation adds 65% ethanol again, fully stir, placed 4 hours, and filtered, merge with above-mentioned filtrate, decompression recycling ethanol also is concentrated into relative density 1.18～1.20, spray drying gets fine powder and crosses 100 mesh sieves, gets semi-synthetic fatty acid ester 390g water-bath fusing by weight, adding above-mentioned fine powder stirs, its medicated powder and semi-synthetic fatty acid ester, ratio are 1.1: 1.4, annotate film while hot, make 270 suppositorys after the cooled and solidified, every heavy 2.5g.
Clinical observation:
1. disease symptoms: the puckery pain of frequent micturition that cures mainly bacterium property prostatitis and cause, it is not smooth to drench drop, and the difficulty in urination is obstructed, lower abdomen overflow, diseases such as dry mouth and throat.
2. case is selected: observe altogether and have above-mentioned clinical symptoms 8 routine patients, and all from the attached first hospital outpatient patient of Heilongjiang University of Chinese Medicine, male, age 38-62 year, the course of disease 25 days-2 years.
3. usage and dosage: anum administration, every day 2 times, each 1.
4. curative effect: 7 days per courses of treatment, 6 routine patient's diseases disappear, produce effects, and 2 routine patient symptoms alleviate, and take a turn for the better.
Claims (2)
1, the prostatitic fat-soluble Chinese medicine suppository of a kind of treatment, the clear suppository that drenches, it is characterized in that making: Herba Dianthi 440-460 Fen, Herba Polygoni Avicularis 440-460 part, Caulis Aristolochiae Manshuriensis 440-460 part, Semen Plantaginis (salt stir-fry) 440-460 part, Talcum 440-460 part, Fructus Gardeniae 440-460 part, Radix Et Rhizoma Rhei 440-460 part, Radix Glycyrrhizae (processing) 440-460 part, semi-synthetic fatty acid ester 380-400 part by the following weight proportion raw material.
2, the preparation method of treatment prostatitis suppository, it is characterized in that by weight ratio: get Herba Dianthi 440-460 part Herba Polygoni Avicularis 440-460 part, Caulis Aristolochiae Manshuriensis 440-460 part, Semen Plantaginis (salt stir-fry) 440-460 part, Talcum 440-460 part, Fructus Gardeniae 440-460 part, Radix Et Rhizoma Rhei 440-460 part, Radix Glycyrrhizae (processing) 440-460 part, decoct with water three times, each 1 hour, add for the first time 10 times of amounts of water, second, add 8 times of amounts of water for the third time, collecting decoction filters, and filtrate is concentrated into 1: 1.5, adding ethanol makes and contains alcohol amount and reach 65%, fully stir, placed 24 hours, filter, it is an amount of that precipitation adds 65% ethanol again, fully stir and placed 4 hours, filter, merge decompression recycling ethanol to relative density 1.18-1.20 with above-mentioned filtrate, spray drying, get fine powder and cross 100 mesh sieves, get semi-synthetic fatty acid ester 380-400 part water-bath fusing by weight, add above-mentioned fine powder and stir, its medicated powder and semi-synthetic fatty acid ester are annotated film by a certain percentage while hot, promptly get after the cooled and solidified to treat prostatitic suppository.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA031028411A CN1520842A (en) | 2003-01-29 | 2003-01-29 | Liposoluble suppository for treating prostatitis |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA031028411A CN1520842A (en) | 2003-01-29 | 2003-01-29 | Liposoluble suppository for treating prostatitis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1520842A true CN1520842A (en) | 2004-08-18 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNA031028411A Pending CN1520842A (en) | 2003-01-29 | 2003-01-29 | Liposoluble suppository for treating prostatitis |
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| CN (1) | CN1520842A (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100389796C (en) * | 2005-12-29 | 2008-05-28 | 天津市曹开镛中医男科研究所 | Chinese medicinal preparation for treating chronic prostatitis and its manufacturing method |
| WO2010125408A3 (en) * | 2009-05-01 | 2011-03-03 | Giorgi Gogbaidze | Prostata-norm rectal suppositories for the treatment of prostatitis |
| CN102895328A (en) * | 2012-10-26 | 2013-01-30 | 施瑞客（天津）生物技术有限公司 | Traditional Chinese medicine composition for treating feline and canine urocystitis |
-
2003
- 2003-01-29 CN CNA031028411A patent/CN1520842A/en active Pending
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100389796C (en) * | 2005-12-29 | 2008-05-28 | 天津市曹开镛中医男科研究所 | Chinese medicinal preparation for treating chronic prostatitis and its manufacturing method |
| WO2010125408A3 (en) * | 2009-05-01 | 2011-03-03 | Giorgi Gogbaidze | Prostata-norm rectal suppositories for the treatment of prostatitis |
| CN102895328A (en) * | 2012-10-26 | 2013-01-30 | 施瑞客（天津）生物技术有限公司 | Traditional Chinese medicine composition for treating feline and canine urocystitis |
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