CN1294136C - 用于治疗的烟碱乙酰胆碱受体新型配体 - Google Patents
用于治疗的烟碱乙酰胆碱受体新型配体 Download PDFInfo
- Publication number
- CN1294136C CN1294136C CNB028110498A CN02811049A CN1294136C CN 1294136 C CN1294136 C CN 1294136C CN B028110498 A CNB028110498 A CN B028110498A CN 02811049 A CN02811049 A CN 02811049A CN 1294136 C CN1294136 C CN 1294136C
- Authority
- CN
- China
- Prior art keywords
- disease
- treatment
- illness
- application
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/02—Antidotes
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US29520601P | 2001-06-01 | 2001-06-01 | |
US60/295,206 | 2001-06-01 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN1512995A CN1512995A (zh) | 2004-07-14 |
CN1294136C true CN1294136C (zh) | 2007-01-10 |
Family
ID=23136711
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CNB028110498A Expired - Fee Related CN1294136C (zh) | 2001-06-01 | 2002-05-29 | 用于治疗的烟碱乙酰胆碱受体新型配体 |
Country Status (19)
Country | Link |
---|---|
EP (1) | EP1397366B1 (pt) |
JP (1) | JP2004532877A (pt) |
KR (1) | KR20040003021A (pt) |
CN (1) | CN1294136C (pt) |
AT (1) | ATE353332T1 (pt) |
BR (1) | BR0210075A (pt) |
CA (1) | CA2455341A1 (pt) |
DE (1) | DE60218032T2 (pt) |
DK (1) | DK1397366T3 (pt) |
ES (1) | ES2280538T3 (pt) |
HK (1) | HK1063787A1 (pt) |
IL (1) | IL158735A0 (pt) |
MX (1) | MXPA03010996A (pt) |
NO (1) | NO20035333D0 (pt) |
NZ (1) | NZ529426A (pt) |
PT (1) | PT1397366E (pt) |
SI (1) | SI1397366T1 (pt) |
WO (1) | WO2002096912A1 (pt) |
ZA (1) | ZA200308779B (pt) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE10164139A1 (de) | 2001-12-27 | 2003-07-10 | Bayer Ag | 2-Heteroarylcarbonsäureamide |
NZ561993A (en) | 2002-04-18 | 2008-09-26 | Astrazeneca Ab | Spiroazabicyclic heterocyclic amines as potent ligands for nicotinic acetylcholine receptors |
EP1499618B1 (en) * | 2002-04-18 | 2010-10-13 | AstraZeneca AB | Furyl compounds |
US7186836B2 (en) * | 2002-04-18 | 2007-03-06 | Astrazeneca Ab | Thienyl compounds |
CN100494202C (zh) * | 2003-10-21 | 2009-06-03 | 阿斯利康(瑞典)有限公司 | 螺呋喃并吡啶芳基衍生物 |
TW200813067A (en) * | 2006-05-17 | 2008-03-16 | Astrazeneca Ab | Nicotinic acetylcholine receptor ligands |
SA08290475B1 (ar) | 2007-08-02 | 2013-06-22 | Targacept Inc | (2s، 3r)-n-(2-((3-بيردينيل)ميثيل)-1-آزا بيسيكلو[2، 2، 2]أوكت-3-يل)بنزو فيوران-2-كربوكساميد، وصور أملاحه الجديدة وطرق استخدامه |
EA201001889A1 (ru) | 2008-06-20 | 2011-08-30 | Астразенека Аб | Производные дибензотиазепина и их применение |
TW201031664A (en) | 2009-01-26 | 2010-09-01 | Targacept Inc | Preparation and therapeutic applications of (2S,3R)-N-2-((3-pyridinyl)methyl)-1-azabicyclo[2.2.2]oct-3-yl)-3,5-difluorobenzamide |
AU2011256287B2 (en) | 2010-05-17 | 2016-11-10 | Envivo Pharmaceuticals, Inc. | A crystalline form of (R)-7-chloro-N-(quinuclidin-3-yl)benzo[b]thiophene-2-carboxamide hydrochloride monohydrate |
GB201111705D0 (en) | 2011-07-07 | 2011-08-24 | Takeda Pharmaceutical | Compounds and their use |
GB201111704D0 (en) | 2011-07-07 | 2011-08-24 | Takeda Pharmaceutical | Novel compounds |
JO3115B1 (ar) | 2011-08-22 | 2017-09-20 | Takeda Pharmaceuticals Co | مركبات بيريدازينون واستخدامها كمثبطات daao |
RU2017136693A (ru) | 2012-05-08 | 2019-02-08 | Форум Фармасьютикалз, Инк. | Способы поддержания, лечения или улучшения когнитивной функции |
GB201209587D0 (en) | 2012-05-30 | 2012-07-11 | Takeda Pharmaceutical | Therapeutic compounds |
US9593106B2 (en) | 2013-02-07 | 2017-03-14 | Heptares Therapeutics Limited | Piperidin-1-yl and azepin-1-yl carboxylates as muscarinic M4 receptor agonists |
CA2914263C (en) | 2013-06-21 | 2021-05-18 | Takeda Pharmaceutical Company Limited | 1-sulfonyl piperidine derivatives as modulators of prokineticin receptors |
GB201314286D0 (en) | 2013-08-08 | 2013-09-25 | Takeda Pharmaceutical | Therapeutic Compounds |
GB201318222D0 (en) | 2013-10-15 | 2013-11-27 | Takeda Pharmaceutical | Novel compounds |
GB201320905D0 (en) | 2013-11-27 | 2014-01-08 | Takeda Pharmaceutical | Therapeutic compounds |
TW201613864A (en) | 2014-02-20 | 2016-04-16 | Takeda Pharmaceutical | Novel compounds |
GB201616839D0 (en) | 2016-10-04 | 2016-11-16 | Takeda Pharmaceutical Company Limited | Therapeutic compounds |
GB201619514D0 (en) | 2016-11-18 | 2017-01-04 | Takeda Pharmaceuticals Co | Novel compounds |
JP2021138648A (ja) | 2020-03-04 | 2021-09-16 | 武田薬品工業株式会社 | 経口固形製剤 |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1999003859A1 (en) * | 1997-07-18 | 1999-01-28 | Astra Aktiebolag | Novel spiroazabicyclic heterocyclic compounds |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NZ500643A (en) * | 1997-05-30 | 2001-12-21 | Neurosearch As | Spiro-quinuclidine derivatives and their use in treating conditions responsive to nicotinic ACh receptor modulators |
SE9900100D0 (sv) * | 1999-01-15 | 1999-01-15 | Astra Ab | New compounds |
-
2002
- 2002-05-29 DK DK02731063T patent/DK1397366T3/da active
- 2002-05-29 NZ NZ529426A patent/NZ529426A/en unknown
- 2002-05-29 JP JP2003500091A patent/JP2004532877A/ja active Pending
- 2002-05-29 AT AT02731063T patent/ATE353332T1/de not_active IP Right Cessation
- 2002-05-29 SI SI200230510T patent/SI1397366T1/sl unknown
- 2002-05-29 EP EP02731063A patent/EP1397366B1/en not_active Expired - Lifetime
- 2002-05-29 CA CA002455341A patent/CA2455341A1/en not_active Abandoned
- 2002-05-29 WO PCT/SE2002/001031 patent/WO2002096912A1/en active IP Right Grant
- 2002-05-29 DE DE60218032T patent/DE60218032T2/de not_active Expired - Fee Related
- 2002-05-29 KR KR10-2003-7015462A patent/KR20040003021A/ko not_active Application Discontinuation
- 2002-05-29 BR BR0210075-4A patent/BR0210075A/pt not_active IP Right Cessation
- 2002-05-29 CN CNB028110498A patent/CN1294136C/zh not_active Expired - Fee Related
- 2002-05-29 PT PT02731063T patent/PT1397366E/pt unknown
- 2002-05-29 IL IL15873502A patent/IL158735A0/xx unknown
- 2002-05-29 MX MXPA03010996A patent/MXPA03010996A/es active IP Right Grant
- 2002-05-29 ES ES02731063T patent/ES2280538T3/es not_active Expired - Lifetime
-
2003
- 2003-11-11 ZA ZA200308779A patent/ZA200308779B/en unknown
- 2003-11-28 NO NO20035333A patent/NO20035333D0/no unknown
-
2004
- 2004-09-01 HK HK04106588A patent/HK1063787A1/xx not_active IP Right Cessation
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1999003859A1 (en) * | 1997-07-18 | 1999-01-28 | Astra Aktiebolag | Novel spiroazabicyclic heterocyclic compounds |
Also Published As
Publication number | Publication date |
---|---|
EP1397366B1 (en) | 2007-02-07 |
ZA200308779B (en) | 2005-02-11 |
ES2280538T3 (es) | 2007-09-16 |
NO20035333D0 (no) | 2003-11-28 |
DK1397366T3 (da) | 2007-05-07 |
HK1063787A1 (en) | 2005-01-14 |
IL158735A0 (en) | 2004-05-12 |
MXPA03010996A (es) | 2004-02-27 |
BR0210075A (pt) | 2004-08-17 |
WO2002096912A1 (en) | 2002-12-05 |
CA2455341A1 (en) | 2002-12-05 |
DE60218032D1 (de) | 2007-03-22 |
ATE353332T1 (de) | 2007-02-15 |
SI1397366T1 (sl) | 2007-06-30 |
CN1512995A (zh) | 2004-07-14 |
EP1397366A1 (en) | 2004-03-17 |
KR20040003021A (ko) | 2004-01-07 |
PT1397366E (pt) | 2007-04-30 |
DE60218032T2 (de) | 2007-08-16 |
NZ529426A (en) | 2005-07-29 |
JP2004532877A (ja) | 2004-10-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
C14 | Grant of patent or utility model | ||
GR01 | Patent grant | ||
C19 | Lapse of patent right due to non-payment of the annual fee | ||
CF01 | Termination of patent right due to non-payment of annual fee |