CN118251204A - 化妆品 - Google Patents
化妆品 Download PDFInfo
- Publication number
- CN118251204A CN118251204A CN202280074583.5A CN202280074583A CN118251204A CN 118251204 A CN118251204 A CN 118251204A CN 202280074583 A CN202280074583 A CN 202280074583A CN 118251204 A CN118251204 A CN 118251204A
- Authority
- CN
- China
- Prior art keywords
- cosmetic
- component
- amount
- polyoxyethylene
- cosmetic according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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- 239000002537 cosmetic Substances 0.000 title claims abstract description 65
- -1 cyclic carboxamide Chemical class 0.000 claims abstract description 78
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 26
- 229920003043 Cellulose fiber Polymers 0.000 claims abstract description 23
- 150000003839 salts Chemical class 0.000 claims abstract description 14
- 239000000835 fiber Substances 0.000 claims description 13
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims description 8
- 125000001183 hydrocarbyl group Chemical group 0.000 claims description 7
- 238000002156 mixing Methods 0.000 claims description 7
- 125000004432 carbon atom Chemical group C* 0.000 claims description 6
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims description 6
- 239000002202 Polyethylene glycol Substances 0.000 claims description 5
- 229920001223 polyethylene glycol Polymers 0.000 claims description 5
- HBAIZGPCSAAFSU-UHFFFAOYSA-N 1-(2-hydroxyethyl)imidazolidin-2-one Chemical compound OCCN1CCNC1=O HBAIZGPCSAAFSU-UHFFFAOYSA-N 0.000 claims description 3
- 125000002768 hydroxyalkyl group Chemical group 0.000 claims description 3
- 229920003171 Poly (ethylene oxide) Polymers 0.000 description 17
- 235000014113 dietary fatty acids Nutrition 0.000 description 16
- 239000000194 fatty acid Substances 0.000 description 16
- 229930195729 fatty acid Natural products 0.000 description 16
- 235000010980 cellulose Nutrition 0.000 description 14
- 229920002678 cellulose Polymers 0.000 description 14
- 239000001913 cellulose Substances 0.000 description 14
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 10
- KWIUHFFTVRNATP-UHFFFAOYSA-N glycine betaine Chemical compound C[N+](C)(C)CC([O-])=O KWIUHFFTVRNATP-UHFFFAOYSA-N 0.000 description 10
- 150000004665 fatty acids Chemical class 0.000 description 8
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 description 7
- 239000004359 castor oil Substances 0.000 description 7
- 235000019438 castor oil Nutrition 0.000 description 7
- ZEMPKEQAKRGZGQ-XOQCFJPHSA-N glycerol triricinoleate Natural products CCCCCC[C@@H](O)CC=CCCCCCCCC(=O)OC[C@@H](COC(=O)CCCCCCCC=CC[C@@H](O)CCCCCC)OC(=O)CCCCCCCC=CC[C@H](O)CCCCCC ZEMPKEQAKRGZGQ-XOQCFJPHSA-N 0.000 description 7
- 239000011734 sodium Substances 0.000 description 7
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 6
- 125000003172 aldehyde group Chemical group 0.000 description 6
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 description 6
- 239000002121 nanofiber Substances 0.000 description 6
- 229910052708 sodium Inorganic materials 0.000 description 6
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 5
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 description 5
- 229960003237 betaine Drugs 0.000 description 5
- 210000001724 microfibril Anatomy 0.000 description 5
- 239000000203 mixture Substances 0.000 description 5
- 229920002503 polyoxyethylene-polyoxypropylene Polymers 0.000 description 5
- 239000000047 product Substances 0.000 description 5
- VBICKXHEKHSIBG-UHFFFAOYSA-N 1-monostearoylglycerol Chemical compound CCCCCCCCCCCCCCCCCC(=O)OCC(O)CO VBICKXHEKHSIBG-UHFFFAOYSA-N 0.000 description 4
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 description 4
- QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 description 4
- 239000002253 acid Substances 0.000 description 4
- 239000003795 chemical substances by application Substances 0.000 description 4
- 230000000694 effects Effects 0.000 description 4
- RTZKZFJDLAIYFH-UHFFFAOYSA-N ether Substances CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 4
- 235000011187 glycerol Nutrition 0.000 description 4
- 239000004615 ingredient Substances 0.000 description 4
- 239000003755 preservative agent Substances 0.000 description 4
- 230000002335 preservative effect Effects 0.000 description 4
- KDYFGRWQOYBRFD-UHFFFAOYSA-N succinic acid Chemical compound OC(=O)CCC(O)=O KDYFGRWQOYBRFD-UHFFFAOYSA-N 0.000 description 4
- 230000008719 thickening Effects 0.000 description 4
- QCDWFXQBSFUVSP-UHFFFAOYSA-N 2-phenoxyethanol Chemical compound OCCOC1=CC=CC=C1 QCDWFXQBSFUVSP-UHFFFAOYSA-N 0.000 description 3
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 description 3
- KWYUFKZDYYNOTN-UHFFFAOYSA-M Potassium hydroxide Chemical compound [OH-].[K+] KWYUFKZDYYNOTN-UHFFFAOYSA-M 0.000 description 3
- LCTONWCANYUPML-UHFFFAOYSA-N Pyruvic acid Chemical compound CC(=O)C(O)=O LCTONWCANYUPML-UHFFFAOYSA-N 0.000 description 3
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 3
- GSEJCLTVZPLZKY-UHFFFAOYSA-N Triethanolamine Chemical class OCCN(CCO)CCO GSEJCLTVZPLZKY-UHFFFAOYSA-N 0.000 description 3
- 239000002280 amphoteric surfactant Substances 0.000 description 3
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 3
- 229920001577 copolymer Polymers 0.000 description 3
- 239000013078 crystal Substances 0.000 description 3
- 239000006185 dispersion Substances 0.000 description 3
- 239000003814 drug Substances 0.000 description 3
- 239000002736 nonionic surfactant Substances 0.000 description 3
- 229960005323 phenoxyethanol Drugs 0.000 description 3
- 239000000843 powder Substances 0.000 description 3
- BDERNNFJNOPAEC-UHFFFAOYSA-N propan-1-ol Chemical compound CCCO BDERNNFJNOPAEC-UHFFFAOYSA-N 0.000 description 3
- 239000007787 solid Substances 0.000 description 3
- 229940104261 taurate Drugs 0.000 description 3
- VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 description 3
- PUPZLCDOIYMWBV-UHFFFAOYSA-N (+/-)-1,3-Butanediol Chemical compound CC(O)CCO PUPZLCDOIYMWBV-UHFFFAOYSA-N 0.000 description 2
- CYDQOEWLBCCFJZ-UHFFFAOYSA-N 4-(4-fluorophenyl)oxane-4-carboxylic acid Chemical compound C=1C=C(F)C=CC=1C1(C(=O)O)CCOCC1 CYDQOEWLBCCFJZ-UHFFFAOYSA-N 0.000 description 2
- 240000000073 Achillea millefolium Species 0.000 description 2
- 235000007754 Achillea millefolium Nutrition 0.000 description 2
- QFOHBWFCKVYLES-UHFFFAOYSA-N Butylparaben Chemical compound CCCCOC(=O)C1=CC=C(O)C=C1 QFOHBWFCKVYLES-UHFFFAOYSA-N 0.000 description 2
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 2
- 235000017788 Cydonia oblonga Nutrition 0.000 description 2
- RGHNJXZEOKUKBD-SQOUGZDYSA-N D-gluconic acid Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C(O)=O RGHNJXZEOKUKBD-SQOUGZDYSA-N 0.000 description 2
- WHUUTDBJXJRKMK-UHFFFAOYSA-N Glutamic acid Natural products OC(=O)C(N)CCC(O)=O WHUUTDBJXJRKMK-UHFFFAOYSA-N 0.000 description 2
- 229920000161 Locust bean gum Polymers 0.000 description 2
- 229920000168 Microcrystalline cellulose Polymers 0.000 description 2
- QZXSMBBFBXPQHI-UHFFFAOYSA-N N-(dodecanoyl)ethanolamine Chemical compound CCCCCCCCCCCC(=O)NCCO QZXSMBBFBXPQHI-UHFFFAOYSA-N 0.000 description 2
- PVNIIMVLHYAWGP-UHFFFAOYSA-N Niacin Chemical compound OC(=O)C1=CC=CN=C1 PVNIIMVLHYAWGP-UHFFFAOYSA-N 0.000 description 2
- DFPAKSUCGFBDDF-UHFFFAOYSA-N Nicotinamide Chemical compound NC(=O)C1=CC=CN=C1 DFPAKSUCGFBDDF-UHFFFAOYSA-N 0.000 description 2
- 229910019142 PO4 Inorganic materials 0.000 description 2
- 244000046052 Phaseolus vulgaris Species 0.000 description 2
- 235000010627 Phaseolus vulgaris Nutrition 0.000 description 2
- NBIIXXVUZAFLBC-UHFFFAOYSA-N Phosphoric acid Chemical compound OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 description 2
- 229920001214 Polysorbate 60 Polymers 0.000 description 2
- VYGQUTWHTHXGQB-FFHKNEKCSA-N Retinol Palmitate Chemical compound CCCCCCCCCCCCCCCC(=O)OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C VYGQUTWHTHXGQB-FFHKNEKCSA-N 0.000 description 2
- 240000002547 Rosa roxburghii Species 0.000 description 2
- 235000000640 Rosa roxburghii Nutrition 0.000 description 2
- CDBYLPFSWZWCQE-UHFFFAOYSA-L Sodium Carbonate Chemical compound [Na+].[Na+].[O-]C([O-])=O CDBYLPFSWZWCQE-UHFFFAOYSA-L 0.000 description 2
- 229920002125 Sokalan® Polymers 0.000 description 2
- DKGAVHZHDRPRBM-UHFFFAOYSA-N Tert-Butanol Chemical compound CC(C)(C)O DKGAVHZHDRPRBM-UHFFFAOYSA-N 0.000 description 2
- 150000003973 alkyl amines Chemical class 0.000 description 2
- 125000000217 alkyl group Chemical group 0.000 description 2
- FPIPGXGPPPQFEQ-OVSJKPMPSA-N all-trans-retinol Chemical compound OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-OVSJKPMPSA-N 0.000 description 2
- WQZGKKKJIJFFOK-PHYPRBDBSA-N alpha-D-galactose Chemical compound OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@H]1O WQZGKKKJIJFFOK-PHYPRBDBSA-N 0.000 description 2
- 229940009868 aluminum magnesium silicate Drugs 0.000 description 2
- WMGSQTMJHBYJMQ-UHFFFAOYSA-N aluminum;magnesium;silicate Chemical compound [Mg+2].[Al+3].[O-][Si]([O-])([O-])[O-] WMGSQTMJHBYJMQ-UHFFFAOYSA-N 0.000 description 2
- 229940053200 antiepileptics fatty acid derivative Drugs 0.000 description 2
- 239000003963 antioxidant agent Substances 0.000 description 2
- 230000003078 antioxidant effect Effects 0.000 description 2
- 235000006708 antioxidants Nutrition 0.000 description 2
- BQMNFPBUAQPINY-UHFFFAOYSA-N azane;2-methyl-2-(prop-2-enoylamino)propane-1-sulfonic acid Chemical compound [NH4+].[O-]S(=O)(=O)CC(C)(C)NC(=O)C=C BQMNFPBUAQPINY-UHFFFAOYSA-N 0.000 description 2
- 229960000686 benzalkonium chloride Drugs 0.000 description 2
- WPYMKLBDIGXBTP-UHFFFAOYSA-N benzoic acid Chemical compound OC(=O)C1=CC=CC=C1 WPYMKLBDIGXBTP-UHFFFAOYSA-N 0.000 description 2
- CADWTSSKOVRVJC-UHFFFAOYSA-N benzyl(dimethyl)azanium;chloride Chemical compound [Cl-].C[NH+](C)CC1=CC=CC=C1 CADWTSSKOVRVJC-UHFFFAOYSA-N 0.000 description 2
- RYYVLZVUVIJVGH-UHFFFAOYSA-N caffeine Chemical compound CN1C(=O)N(C)C(=O)C2=C1N=CN2C RYYVLZVUVIJVGH-UHFFFAOYSA-N 0.000 description 2
- 229910052799 carbon Inorganic materials 0.000 description 2
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 description 2
- 230000000052 comparative effect Effects 0.000 description 2
- 229920006037 cross link polymer Polymers 0.000 description 2
- SZXQTJUDPRGNJN-UHFFFAOYSA-N dipropylene glycol Chemical compound OCCCOCCCO SZXQTJUDPRGNJN-UHFFFAOYSA-N 0.000 description 2
- 229940079593 drug Drugs 0.000 description 2
- 150000002148 esters Chemical class 0.000 description 2
- 238000011156 evaluation Methods 0.000 description 2
- 125000002791 glucosyl group Chemical group C1([C@H](O)[C@@H](O)[C@H](O)[C@H](O1)CO)* 0.000 description 2
- 239000004220 glutamic acid Substances 0.000 description 2
- 235000013922 glutamic acid Nutrition 0.000 description 2
- 150000004676 glycans Chemical class 0.000 description 2
- YQEMORVAKMFKLG-UHFFFAOYSA-N glycerine monostearate Natural products CCCCCCCCCCCCCCCCCC(=O)OC(CO)CO YQEMORVAKMFKLG-UHFFFAOYSA-N 0.000 description 2
- SVUQHVRAGMNPLW-UHFFFAOYSA-N glycerol monostearate Natural products CCCCCCCCCCCCCCCCC(=O)OCC(O)CO SVUQHVRAGMNPLW-UHFFFAOYSA-N 0.000 description 2
- 239000003906 humectant Substances 0.000 description 2
- BJRNKVDFDLYUGJ-RMPHRYRLSA-N hydroquinone O-beta-D-glucopyranoside Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC1=CC=C(O)C=C1 BJRNKVDFDLYUGJ-RMPHRYRLSA-N 0.000 description 2
- ZXEKIIBDNHEJCQ-UHFFFAOYSA-N isobutanol Chemical compound CC(C)CO ZXEKIIBDNHEJCQ-UHFFFAOYSA-N 0.000 description 2
- 235000010420 locust bean gum Nutrition 0.000 description 2
- 239000000711 locust bean gum Substances 0.000 description 2
- 239000006210 lotion Substances 0.000 description 2
- 159000000003 magnesium salts Chemical class 0.000 description 2
- VZCYOOQTPOCHFL-UPHRSURJSA-N maleic acid Chemical compound OC(=O)\C=C/C(O)=O VZCYOOQTPOCHFL-UPHRSURJSA-N 0.000 description 2
- 230000000873 masking effect Effects 0.000 description 2
- 238000005259 measurement Methods 0.000 description 2
- 229910021645 metal ion Inorganic materials 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- LXCFILQKKLGQFO-UHFFFAOYSA-N methylparaben Chemical compound COC(=O)C1=CC=C(O)C=C1 LXCFILQKKLGQFO-UHFFFAOYSA-N 0.000 description 2
- 229940016286 microcrystalline cellulose Drugs 0.000 description 2
- 235000019813 microcrystalline cellulose Nutrition 0.000 description 2
- 239000008108 microcrystalline cellulose Substances 0.000 description 2
- 230000003472 neutralizing effect Effects 0.000 description 2
- 239000003921 oil Substances 0.000 description 2
- 239000003002 pH adjusting agent Substances 0.000 description 2
- 239000008177 pharmaceutical agent Substances 0.000 description 2
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 2
- 239000010452 phosphate Substances 0.000 description 2
- 229920001983 poloxamer Polymers 0.000 description 2
- 235000010482 polyoxyethylene sorbitan monooleate Nutrition 0.000 description 2
- 239000000244 polyoxyethylene sorbitan monooleate Substances 0.000 description 2
- 235000010989 polyoxyethylene sorbitan monostearate Nutrition 0.000 description 2
- 239000001818 polyoxyethylene sorbitan monostearate Substances 0.000 description 2
- 229920001282 polysaccharide Polymers 0.000 description 2
- 239000005017 polysaccharide Substances 0.000 description 2
- 229920000053 polysorbate 80 Polymers 0.000 description 2
- 238000002360 preparation method Methods 0.000 description 2
- 238000007670 refining Methods 0.000 description 2
- YGSDEFSMJLZEOE-UHFFFAOYSA-N salicylic acid Chemical compound OC(=O)C1=CC=CC=C1O YGSDEFSMJLZEOE-UHFFFAOYSA-N 0.000 description 2
- 239000001509 sodium citrate Substances 0.000 description 2
- NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 description 2
- 239000001540 sodium lactate Substances 0.000 description 2
- 229940005581 sodium lactate Drugs 0.000 description 2
- 235000011088 sodium lactate Nutrition 0.000 description 2
- 229940074404 sodium succinate Drugs 0.000 description 2
- ZDQYSKICYIVCPN-UHFFFAOYSA-L sodium succinate (anhydrous) Chemical compound [Na+].[Na+].[O-]C(=O)CCC([O-])=O ZDQYSKICYIVCPN-UHFFFAOYSA-L 0.000 description 2
- 239000004094 surface-active agent Substances 0.000 description 2
- 239000002562 thickening agent Substances 0.000 description 2
- 229940006284 undaria pinnatifida extract Drugs 0.000 description 2
- BAERPNBPLZWCES-UHFFFAOYSA-N (2-hydroxy-1-phosphonoethyl)phosphonic acid Chemical compound OCC(P(O)(O)=O)P(O)(O)=O BAERPNBPLZWCES-UHFFFAOYSA-N 0.000 description 1
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 description 1
- CUNWUEBNSZSNRX-RKGWDQTMSA-N (2r,3r,4r,5s)-hexane-1,2,3,4,5,6-hexol;(z)-octadec-9-enoic acid Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO.OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO.CCCCCCCC\C=C/CCCCCCCC(O)=O.CCCCCCCC\C=C/CCCCCCCC(O)=O.CCCCCCCC\C=C/CCCCCCCC(O)=O CUNWUEBNSZSNRX-RKGWDQTMSA-N 0.000 description 1
- JNYAEWCLZODPBN-JGWLITMVSA-N (2r,3r,4s)-2-[(1r)-1,2-dihydroxyethyl]oxolane-3,4-diol Chemical compound OC[C@@H](O)[C@H]1OC[C@H](O)[C@H]1O JNYAEWCLZODPBN-JGWLITMVSA-N 0.000 description 1
- ZYJZBFYRVKLOAA-KRWDZBQOSA-N (2s)-2-(hexadecanoylamino)butanedioic acid Chemical compound CCCCCCCCCCCCCCCC(=O)N[C@H](C(O)=O)CC(O)=O ZYJZBFYRVKLOAA-KRWDZBQOSA-N 0.000 description 1
- HSINOMROUCMIEA-FGVHQWLLSA-N (2s,4r)-4-[(3r,5s,6r,7r,8s,9s,10s,13r,14s,17r)-6-ethyl-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1h-cyclopenta[a]phenanthren-17-yl]-2-methylpentanoic acid Chemical class C([C@@]12C)C[C@@H](O)C[C@H]1[C@@H](CC)[C@@H](O)[C@@H]1[C@@H]2CC[C@]2(C)[C@@H]([C@H](C)C[C@H](C)C(O)=O)CC[C@H]21 HSINOMROUCMIEA-FGVHQWLLSA-N 0.000 description 1
- RUHCWQAFCGVQJX-RVWHZBQESA-N (3s,8s,9s,10r,13r,14s,17r)-3-hydroxy-10,13-dimethyl-17-[(2r)-6-methylheptan-2-yl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-1-one Chemical compound C1C=C2C[C@H](O)CC(=O)[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 RUHCWQAFCGVQJX-RVWHZBQESA-N 0.000 description 1
- PSBDWGZCVUAZQS-UHFFFAOYSA-N (dimethylsulfonio)acetate Chemical compound C[S+](C)CC([O-])=O PSBDWGZCVUAZQS-UHFFFAOYSA-N 0.000 description 1
- ZORQXIQZAOLNGE-UHFFFAOYSA-N 1,1-difluorocyclohexane Chemical compound FC1(F)CCCCC1 ZORQXIQZAOLNGE-UHFFFAOYSA-N 0.000 description 1
- PQUXFUBNSYCQAL-UHFFFAOYSA-N 1-(2,3-difluorophenyl)ethanone Chemical compound CC(=O)C1=CC=CC(F)=C1F PQUXFUBNSYCQAL-UHFFFAOYSA-N 0.000 description 1
- IXPNQXFRVYWDDI-UHFFFAOYSA-N 1-methyl-2,4-dioxo-1,3-diazinane-5-carboximidamide Chemical compound CN1CC(C(N)=N)C(=O)NC1=O IXPNQXFRVYWDDI-UHFFFAOYSA-N 0.000 description 1
- FPIPGXGPPPQFEQ-UHFFFAOYSA-N 13-cis retinol Natural products OCC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-UHFFFAOYSA-N 0.000 description 1
- JNAYPSWVMNJOPQ-UHFFFAOYSA-N 2,3-bis(16-methylheptadecanoyloxy)propyl 16-methylheptadecanoate Chemical compound CC(C)CCCCCCCCCCCCCCC(=O)OCC(OC(=O)CCCCCCCCCCCCCCC(C)C)COC(=O)CCCCCCCCCCCCCCC(C)C JNAYPSWVMNJOPQ-UHFFFAOYSA-N 0.000 description 1
- SPSPIUSUWPLVKD-UHFFFAOYSA-N 2,3-dibutyl-6-methylphenol Chemical compound CCCCC1=CC=C(C)C(O)=C1CCCC SPSPIUSUWPLVKD-UHFFFAOYSA-N 0.000 description 1
- SGTNSNPWRIOYBX-UHFFFAOYSA-N 2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile Chemical compound C1=C(OC)C(OC)=CC=C1CCN(C)CCCC(C#N)(C(C)C)C1=CC=C(OC)C(OC)=C1 SGTNSNPWRIOYBX-UHFFFAOYSA-N 0.000 description 1
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- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
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- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
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- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
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- A61Q1/00—Make-up preparations; Body powders; Preparations for removing make-up
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- C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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Abstract
[课题]提供使用感优异的化妆品。[解决手段]一种化妆品，其包含：(A)具有特定结构的环状羧酰胺衍生物或其盐、(B)微细纤维素纤维及(C)水。
Description
技术领域
本发明涉及包含具有特定结构的环状羧酰胺衍生物或其盐及微细纤维素纤维而成的化妆品。
背景技术
已知出于赋予增稠性、分散稳定性的目的等而将纤维素纤维微细化后的纤维素纳米纤维配合在化妆品中。例如，提出了包含具有特定的纤维直径和结构的纤维素纤维与增稠促进剂的组合的粘性水系组合物，公开了以少量来提高增稠效果的内容(专利文献1)。对于这样的化妆品，使用者要求具有更优异的使用感，有进一步改善使用感的余地。
另一方面，已知环状羧酰胺衍生物具有抗皱效果、色素沉着抑制效果，提出了在化妆品等中配合环状羧酰胺衍生物的方案(专利文献2)。
现有技术文献
专利文献
专利文献1：日本特开2012-126788号公报
专利文献2：国际公开2011/040496
发明内容
根据本发明人等的研究，了解到在化妆品中使用环状羧酰胺衍生物的情况下，有容易产生粘腻的倾向。本发明人等惊讶地发现，通过使用包含微细纤维素纤维与特定的环状羧酰胺衍生物的组合的化妆品，从而可以实现优异的使用感。本发明基于这些见解。
根据本发明，提供如下发明。
[1]一种化妆品，其包含：
(A)式(1)所示的环状羧酰胺衍生物或其盐；
(B)微细纤维素纤维；及
(C)水，
(式(1)中，
R1为任选被羟基取代的碳数1～6的烃基、或为氢原子，
X为-CH2-或-N(R2)-，此处，R2为任选被羟基取代的碳数1～6的烃基、或为氢原子，并且
n为1～3的整数。)。
[2]根据[1]所述的化妆品，其中，(A)成分的式(1)中，
R1为碳数1～3的羟烷基，
X为-CH2-或-NH-，并且
n为1。
[3]根据[1]或[2]所述的化妆品，其中，(A)成分为1-(2-羟乙基)-2-咪唑啉酮。
[4]根据[1]～[3]中任一项所述的化妆品，其中，(A)成分的配合量相对于化妆品的总量为0.05～7质量％。
[5]根据[1]～[4]中任一项所述的化妆品，其中，(B)成分的最大纤维直径为1000nm以下。
[6]根据[1]～[5]中任一项所述的化妆品，其中，(B)成分的配合量相对于化妆品的总量为0.005～1质量％。
[7]根据[1]～[6]中任一项所述的化妆品，其中，(A)成分的配合量相对于(B)成分的配合量((A)/(B))以质量比计为1～300。
[8]根据[1]～[7]中任一项所述的化妆品，其还包含(D)琥珀酰聚糖。
[9]根据[8]所述的化妆品，其中，(D)成分的配合量相对于化妆品的总量为0.005～1质量％。
[10]根据[1]～[9]中任一项所述的化妆品，其还包含(E)聚乙二醇。
[11]根据[10]所述的化妆品，其中，(E)成分的配合量相对于化妆品的总量为0.1～5质量％。
根据本发明，可以提供使用感优异的化妆品。特别是在涂抹中能够获得水润感、贴合感，并且在涂抹后肌肤感到水润、粘腻也得以抑制。
具体实施方式
本发明涉及包含(A)具有特定结构的环状羧酰胺衍生物或其盐、(B)微细纤维素纤维及(C)水而成的化妆品。
(A)环状羧酰胺衍生物或其盐
本发明的化妆品包含式(1)所示的环状羧酰胺衍生物或其盐(以下有时称为(A)成分。其他成分也同样)。
式(1)中，
R1为任选被羟基取代的碳数1～6的烃基、或为氢原子，
X为-CH2-或-N(R2)-，此处，R2为任选被羟基取代的碳数1～6的烃基、或为氢原子，并且
n为1～3的整数。
上述的烃基没有特别限定，例如可以为烷基、环烷基、烯基、炔基、环烷基烷基、卤代烷基、烷氧基烷基、烷氧基羰基烷基，优选为烷基。
优选方式中，(A)成分的式(1)中，
R1为碳数1～3的羟烷基，
X为-CH2-或-NH-，并且
n为1。
作为式(1)所示的环状羧酰胺衍生物的具体例，例如可列举以下。
(A)成分最优选为1-(2-羟乙基)-2-咪唑啉酮。
(A)成分可以为式(1)所示的环状羧酰胺衍生物的盐。盐的种类只要是药学上可接受的盐就没有特别限定，可以是无机盐也可以是有机盐。作为无机盐，例如可列举出盐酸盐、硫酸盐、磷酸盐、氢溴酸盐、钠盐、钾盐、镁盐、钙盐、镁盐、铵盐等。作为有机盐，例如可列举出醋酸盐、乳酸盐、马来酸盐、富马酸盐、酒石酸盐、甲磺酸盐、对甲苯磺酸盐、三乙醇胺盐、氨基酸盐等。
(A)成分可以配合1种或2种以上。(A)成分的配合量相对于化妆品的总量，优选为0.05～7质量％，更优选为0.1～6质量％，进而优选为1～6质量％。
(B)微细纤维素纤维
本发明的化妆品包含(B)微细纤维素纤维。本发明中，(B)成分是指由植物来源的纤维素构成的纳米纤维(微原纤维)。(B)成分更优选为微原纤维彼此实质上分散成一根一根的微细纤维素纤维(也称为纤维素单纳米纤维：CSNF)。纤维素单纳米纤维具有水中的高增稠作用。
(B)成分优选包含微晶纤维素。更优选地，构成(B)成分的纤维素具有I型晶体结构。在优选的一个方式中，(B)成分为将具有I型晶体结构的天然来源的纤维素固体原料进行表面氧化并微细化的纤维。在天然纤维素的生物合成的过程中，几乎无一例外地首先形成被称为微原纤维的纳米纤维，它们被多束化而构成高阶的固体结构，但在优选方式中，微细纤维素纤维为了减弱成为上述微原纤维间的强聚集力的原动力的表面之间的氢键，其羟基的一部分被氧化并转化为醛基和羧基。
构成微细纤维素纤维的纤维素具有I型晶体结构，例如，在通过广角X射线衍射图像测定得到的衍射曲线中，在2θ＝14～17°附近和2θ＝22～23°附近这2个位置具有典型的峰，因此，可以进行鉴定。
优选方式中，(B)成分是纤维素分子中的葡萄糖单元的C6位的羟基被选择性地氧化而改性成醛基和羧基。羧基量优选为0.6～2.2mmol/g，从保形性能、分散稳定性的观点出发，更优选为0.6～2.0mmol/g。醛基量优选为0.03～0.3mmol/g，更优选为0.10～0.25mmol/g。微细纤维素纤维中包含的羧基量和醛基量的测定可以通过分散有微细纤维素纤维的水的电位滴定来进行。
微细纤维素纤维中的羧基量和醛基量的调整可以通过控制在纤维素纤维的氧化工序中所使用的共氧化剂的添加量、反应时间来进行。另外，可以通过全反射式红外光谱(ATR)分析来确认微细纤维素纤维中导入了醛基或羧基。
(B)成分的最大纤维直径优选为1000nm以下，更优选最大纤维直径为1000nm以下、并且数均纤维直径为2～100nm，从分散稳定性的观点出发，进一步优选最大纤维直径为500nm以下、并且数均纤维直径为3～80nm。
微细纤维素纤维的数均纤维直径和最大纤维直径例如可以如下方式测定。向纤维素纤维中加入水，使纤维素的固体成分为1质量％。使用超声波均化器、高压均化器、具有转速15000rpm以上的能力的混合机等使其分散后，加水稀释，流延至亲水化处理后的碳膜被覆栅极上，通过透射型电子显微镜(TEM)等观察其，根据所得到的图像，可以测定和算出纤维素纤维的数均纤维直径、最大纤维直径。
微细纤维素纤维的上述具体测定方法等可以采用日本专利第5243371号公报中公开的方法。
作为(B)成分，例如可使用由第一工业制药株式会社以“RHEOCRYSTA”的商品名市售的商品。例如，“RHEOCRYSTAC-2SP”(商品名)为在97质量％的水中包含2质量％的微细纤维素纤维、1质量％的苯氧乙醇的制品。
(B)成分的配合量相对于化妆品的总量，优选为0.005～1质量％，更优选为0.005～0.3质量％，进而优选为0.015～0.15质量％，更加进一步优选为0.015～0.08质量％。
(A)成分的配合量相对于(B)成分的配合量((A)/(B))以质量比计优选为1～300，更优选为50～280。
(C)水
本发明的化妆品包含(C)水。作为水，可以使用化妆品、准药物等中使用的水，可以使用例如纯化水、离子交换水、自来水等。
水的配合量相对于本发明的化妆品的总量，优选为40～95质量％，更优选为50～90质量％。
(D)琥珀酰聚糖
本发明的化妆品可以还包含(D)琥珀酰聚糖。琥珀酰聚糖为一种来源于微生物的多糖类，除了由半乳糖和葡萄糖衍生的糖单元之外，还包含由琥珀酸和丙酮酸以及作为任意成分的乙酸、或由这些酸的盐衍生的单元。更具体而言，琥珀酰聚糖为以约7：1：1：1包含葡萄糖单元：半乳糖单元：琥珀酸单元：丙酮酸单元的水溶性高分子。
(D)成分的配合量相对于化妆品的总量，优选为0.005～1质量％，更优选为0.01～0.5质量％，进而优选为0.01～0.1质量％。
(A)成分的配合量相对于(D)成分的配合量((A)/(D))以质量比计优选为1～300，更优选为50～200。
(E)聚乙二醇
本发明的化妆品可以还包含(E)聚乙二醇(PEG)。作为(E)成分的优选的重均分子量为150～23000，更优选为150～3000。作为(E)成分，例如可列举出PEG-6、PEG-20、PEG-32、PEG-75、PEG-400等。
(E)成分可以配合1种或2种以上。(E)成分的配合量相对于化妆品的总量，优选为0.1～5质量％，更优选为0.3～3质量％，进而优选为0.7～2质量％。
本发明的化妆品中，除了上述成分以外，可以配合通常化妆品、药物中使用的任意成分。作为任意成分，例如可列举出保湿剂、低级醇、增稠剂、表面活性剂、金属离子掩蔽剂、中和剂、pH调节剂、抗氧化剂、防腐剂、药剂等，只要起到本发明的效果，就可以配合1种或2种以上。
作为保湿剂，例如可列举出丙二醇、一缩二丙二醇(DPG)、甘油、1,3-丁二醇(BG)、赤藓醇、木糖醇、山梨(糖)醇、麦芽糖醇、硫酸软骨素、透明质酸、硫酸粘多糖、卡隆酸、缺端胶原、胆甾醇羟基硬脂酸酯、乳酸钠、胆汁酸盐、dl-吡咯烷酮羧酸盐、短链可溶性胶原蛋白、刺梨(ROSA ROXBURGHII)果提取物、欧蓍草(ACHILLEA MILLEFOLIUM)提取物、草木犀(MELILOTUS OFFICINALIS)提取物等。
作为低级醇，例如可列举出乙醇、1-丙醇、2-丙醇、异丁醇、叔丁醇等。
作为增稠剂，例如可列举出***胶、角叉菜胶、刺梧桐胶、黄蓍胶、角豆树胶、榅桲籽(榅桲)、酪蛋白、糊精、明胶、果胶酸钠、藻酸钠、PVA、PVM、PVP、聚丙烯酸钠、羧乙烯基聚合物(卡波姆)、二甲基丙烯酰胺/丙烯酰基二甲基牛磺酸钠交联聚合物、丙烯酰二甲基牛磺酸铵/VP共聚物、丙烯酰二甲基牛磺酸铵/山嵛醇聚醚-25甲基丙烯酸酯交联聚合物、丙烯酸钠/丙烯酰二甲基牛磺酸钠共聚物、刺槐豆胶、瓜尔豆胶、酸豆籽胶、黄原胶、硅酸铝镁、膨润土、水辉石、硅酸铝镁(VEEGUM)、合成锂皂石、硅酸酐等。
作为亲油性非离子性表面活性剂，例如可列举出亲油性非离子性表面活性剂，例如可列举出山梨坦单油酸酯、山梨坦单异硬脂酸酯、山梨坦单月桂酸酯、山梨坦单棕榈酸酯、山梨坦单硬脂酸酯、山梨坦倍半油酸酯、双甘油脱水山梨糖醇五-2-乙基己酸酯等山梨坦脂肪酸酯类、单硬脂酸甘油酯、α,α’-油酸焦谷氨酸甘油酯、单硬脂酸苹果酸甘油酯等甘油或聚甘油的酯类、丙二醇单硬脂酸酯等丙二醇脂肪酸酯类、氢化蓖麻油衍生物、甘油烷基醚等。
作为亲水性非离子性表面活性剂，例如可列举出聚氧乙烯山梨坦单油酸酯、聚氧乙烯山梨坦单硬脂酸酯等聚氧乙烯山梨坦脂肪酸酯类；聚氧乙烯山梨坦单月桂酸酯、聚氧乙烯山梨坦单油酸酯、聚氧乙烯山梨坦单硬脂酸酯等聚氧乙烯山梨坦脂肪酸酯类；聚氧乙烯单硬脂酸甘油酯、聚氧乙烯单异硬脂酸甘油酯、聚氧乙烯三异硬脂酸甘油酯等聚氧乙烯脂肪酸甘油酯、聚氧乙烯单油酸酯、聚氧乙烯二硬脂酸酯等聚氧乙烯脂肪酸酯类；聚氧乙烯月桂基醚、聚氧乙烯月油基醚、聚氧乙烯硬脂基醚、聚氧乙烯-2-辛基十二烷基醚、聚氧乙烯胆甾醇醚等聚氧乙烯烷醇醚类；聚氧乙烯辛基苯基醚、聚氧乙烯壬基苯基醚、聚氧乙烯二壬基苯基醚等聚氧乙烯烷基苯基醚类；普朗尼克等普朗尼克型表面活性剂；聚氧乙烯聚氧丙烯鲸蜡醚、聚氧乙烯聚氧丙烯-2-癸基十四烷基醚、聚氧乙烯聚氧丙烯单丁醚、聚氧乙烯聚氧丙烯、氢化羊毛脂、聚氧乙烯聚氧丙烯甘油醚、PPG-13-癸基十四醇聚醚-24等聚氧乙烯聚氧丙烯烷基醚类；Tetronic等四聚氧乙烯·四聚氧丙烯乙烯二胺缩合物类；聚氧乙烯蓖麻油、聚氧乙烯氢化蓖麻油、聚氧乙烯氢化蓖麻油单异硬脂酸酯、聚氧乙烯氢化蓖麻油三异硬脂酸酯、聚氧乙烯氢化蓖麻油单焦谷氨酸单异硬脂酸二酯、聚氧乙烯氢化蓖麻油马来酸酯等聚氧乙烯蓖麻油衍生物或聚氧乙烯氢化蓖麻油衍生物；椰子油脂肪酸二乙醇酰胺、月桂酸单乙醇酰胺、脂肪酸异丙醇酰胺等烷醇酰胺、以及聚氧乙烯丙二醇脂肪酸酯类、聚氧乙烯烷基胺类、聚氧乙烯脂肪酰胺、蔗糖脂肪酸酯、聚氧乙烯壬基苯基甲醛缩合物、烷基乙氧基二甲基胺氧化物、三油醇磷酸酯等。
作为阴离子性表面活性剂，例如可列举出月桂酸钠、棕榈酸钠等脂肪酸皂、月桂醇硫酸酯钠、月桂醇硫酸酯钾等高级烷醇硫酸酯盐；聚氧乙烯月桂醇硫酸酯三乙醇胺、聚氧乙烯月桂醇硫酸酯钠等烷基醚硫酸酯盐；月桂酰肌氨酸钠等N-酰基肌氨酸、N-肉豆蔻酰-N-甲基牛磺酸钠、N-硬脂酰-N-甲基牛磺酸钠、椰子油脂肪酸甲基牛磺酸钠、甲基月桂酰基牛磺酸钠等高级脂肪酸酰胺磺酸盐；聚氧乙烯月油基醚磷酸酯钠、聚氧乙烯硬脂基醚磷酸酯钠等磷酸酯盐；二(2-乙基己基)磺基琥珀酸钠、单月桂酰基单乙醇酰胺聚氧乙烯磺基琥珀酸钠、聚丙二醇月桂醇磺基琥珀酸钠等磺基琥珀酸盐；十二烷基苯磺酸钠、十二烷基苯磺酸三乙醇胺等烷基苯磺酸盐；N-月桂酰谷氨酸单钠、N-硬脂酰谷氨酸二钠等N-酰基谷氨酸；氢化椰子油脂肪酸甘油酯硫酸酯钠等高级脂肪酸酯硫酸酯盐、以及聚氧乙烯烷醇醚羧酸盐、α-烯烃磺酸盐、高级脂肪酸酯磺酸盐、仲醇硫酸酯盐、高级脂肪酸烷基酰胺硫酸酯盐、月桂酰单乙醇酰胺琥珀酸钠、N-棕榈酰天冬氨酸二(三乙醇胺)(日文原文：N－パルミトイルアスパラギン酸ジトリエタノールアミン)、椰子油脂肪酸胶水解碱盐等。
作为阳离子表面活性剂，例如可列举出硬脂基三甲基氯化铵、月桂基三甲基氯化铵等烷基三甲基氯化铵盐、二硬脂基二甲基氯化铵等二烷基二甲基氯化铵盐；聚(N,N’-二甲基-3,5,-二亚甲基哌啶氯)、氯化鲸蜡基吡啶鎓等烷基吡啶鎓盐、以及氨基季铵盐、烷基二甲基苄基铵盐、烷基异喹啉鎓盐、二烷基吗啉鎓盐、聚氧乙烯烷基胺、烷基胺盐、多胺脂肪酸衍生物、戊醇脂肪酸衍生物、苯扎氯铵、苄索氯铵、阳离子聚合物、β-N-N-二甲基-N-乙基氨基丙烯酸乙酯氯化乙烯基吡咯烷酮共聚物(beta-N,N-Dimethyl-N-ethylammonioethylacrylate salt-Vinylpyrrolidonecopolymer)等。
作为两性表面活性剂，例如可列举出2-十一烷基-N,N,N,-(羟乙基羧甲基)-2-咪唑啉钠、2-椰油酰基-2-咪唑鎓羟氧基-1-羧基乙氧基二钠盐等咪唑啉系两性表面活性剂；2-十七烷基-N-羧甲基-N-羟乙基咪唑鎓甜菜碱、月桂基二甲基氨基乙酸甜菜碱、烷基甜菜碱、酰胺甜菜碱、磺基甜菜碱等甜菜碱系两性表面活性剂等。
作为金属离子掩蔽剂，例如可列举出羟基乙叉二膦酸、羟基乙叉二膦酸四钠盐、依地酸二钠(EDTA-2Na)、依地酸三钠、依地酸四钠、柠檬酸钠、多磷酸钠、偏磷酸钠、葡糖酸、磷酸、柠檬酸、琥珀酸、依地酸、HEDTA三钠等。
作为中和剂，例如可列举出2-氨基-2-甲基-1-丙醇、2-氨基-2-甲基-1,3-丙二醇、氢氧化钾、氢氧化钠、三乙醇胺、碳酸钠等。
作为pH调节剂，例如可列举出乳酸-乳酸钠、柠檬酸-柠檬酸钠、琥珀酸-琥珀酸钠等缓冲剂等。
作为抗氧化剂，例如可列举出二丁基羟基甲苯、丁羟基茴香醚、焦亚硫酸钠、没食子酸酯类等。
作为防腐剂，例如可列举出对羟基苯甲酸甲酯、对羟基苯甲酸乙酯、对羟基苯甲酸丁酯等对羟基苯甲酸酯类、苯甲酸、水杨酸、山梨酸、对氯间甲酚、六氯酚、苯扎氯铵、氯己定、三氯碳酰替苯胺、光敏剂、苯氧乙醇等。
作为药剂，例如可列举出抗坏血酸(维生素C)、凝血酸、曲酸、鞣花酸、熊果苷、烷氧基水杨酸、甘草酸、生育酚、视黄醇及这些的盐或衍生物(例如，L-抗坏血酸钠、L-抗坏血酸酯镁盐、L-抗坏血酸葡糖苷、2-O-乙基-L-抗坏血酸、3-O-乙基-L-抗坏血酸、4-甲氧基水杨酸钠盐、4-甲氧基水杨酸钾盐、甘草酸二钾、硬脂醇甘草亭酸酯、生育酚乙酸酯、视黄醇乙酸酯、视黄醇棕榈酸酯等)、烟酸及其衍生物(例如，烟酰胺)、咖啡碱、丹宁、维拉帕米及其衍生物、甘草提取物、光甘草定、火棘果提取物、各种生药、水解蚕丝、贝壳硬蛋白粉、茶叶提取物、洋委陵菜根提取物、滨海当归叶/茎提取物、库拉索芦荟叶提取物、樱花叶提取物、东当归根提取物、扁平橘果皮提取物、香根鸢尾根提取物、齿状麒麟菜/稀疏蜈蚣藻/狭叶糖海带/石莼/裙带菜提取物、水烛穗提取物、香茶菜叶/柄提取物、山茶籽提取物、狭叶糖海带/裙带菜提取物、阿尔泰柴胡根提取物、豆瓣菜叶/茎提取物、肉桂树皮提取物、迷迭香叶油、薰衣草油、谷氨酸、三甲基甘氨酸、氯苯甘醚、薄荷氧基丙二醇等。
此外，也可以适宜配合紫外线吸收剂、粉末成分、香料等。
本发明的化妆品的剂型例如可列举出溶液系、增溶系、乳化系、水2-油二层系、水-油-粉末三层系等，没有特别限定。
作为本发明的化妆品，例如可列举出皮肤护理化妆品(例如，化妆水、乳液、乳霜、美容液、面膜等)、彩妆化妆品(例如，粉底、隔离等)、皮肤清洗剂(例如，洗面奶、卸妆水等)、防晒化妆品、软膏等。
本发明的化妆品可以按照常规方法制造。在本发明的化妆品为乳化化妆品的情况下，乳化的方法没有特别限定。
实施例
基于以下的例子具体说明本发明，但本发明并不限定于这些例子。含量除非另有说明，以相对于总量的质量％表示。
[实施例1～13和比较例1、2]
以表1和2所示的配方制备实施例1～13和比较例1、2的化妆品。
[表1]
[表2]
表中，微晶纤维素(纤维素纳米纤维)*1是最大纤维直径为1000nm以下的微细纤维状纤维素(“RHEOCRYSTAC-2SP”(商品名)、第一工业制药株式会社制)。需要说明的是，“RHEOCRYSTAC-2SP”是在97质量％的水中包含2质量％的微细纤维状纤维素、1质量％的苯氧乙醇(防腐剂)的制品，本说明书和表中记载的质量％仅指微细纤维状纤维素，不包含商品中包含的水、防腐剂。
由10名专业小组成员将上述制备的化妆品涂抹于肌肤上，对于涂抹中的“水润感”、涂抹后的“粘腻的有无”、涂抹后的“水润感”及涂抹中的“贴合感”进行评价。以各专业小组成员的评价为基础，按照以下的基准进行评价。所得到的结果如表1和表2所示。
“水润感”
AA：10名小组成员全部回答有水润的触感。
A：10名小组成员中7名以上且9名以下回答有水润的触感。
B：10名小组成员中4名以上且6名以下回答有水润的触感
C：10名小组成员中1名以上且3名以下回答有水润的触感。
D：小组成员10中全员回答欠缺水润的触感。
“粘腻的有无”
AA：10名小组成员全部回答无粘腻。
A：10名小组成员中7名以上且9名以下回答无粘腻。
B：10名小组成员中4名以上且6名以下回答无粘腻。
C：10名小组成员中1名以上且3名以下回答无粘腻。
D：小组成员10中全员回答有粘腻。
“水润感”
AA：10名小组成员全部回答回答有水润感。
A：10名小组成员中7名以上且9名以下回答回答有水润感。
B：10名小组成员中4名以上且6名以下回答回答有水润感。
C：10名小组成员中1名以上且3名以下回答回答有水润感。
D：10名小组成员全部回答缺少水润感。
“贴合感”
AA：10名小组成员全部回答有贴合感。
A：10名小组成员中7名以上且9名以下回答有贴合感。
B：10名小组成员中4名以上且6名以下回答有贴合感。
C：10名小组成员中1名以上且3名以下回答有贴合感。
D：小组成员10中全员回答欠缺贴合感。
Claims (11)
1.一种化妆品，其包含：
(A)式(1)所示的环状羧酰胺衍生物或其盐；
(B)微细纤维素纤维；及
(C)水，
式(1)中，
R1为任选被羟基取代的碳数1～6的烃基、或为氢原子，
X为-CH2-或-N(R2)-，此处，R2为任选被羟基取代的碳数1～6的烃基、或为氢原子，并且
n为1～3的整数。
2.根据权利要求1所述的化妆品，其中，(A)成分的式(1)中，
R1为碳数1～3的羟烷基，
X为-CH2-或-NH-，并且
n为1。
3.根据权利要求1或2所述的化妆品，其中，(A)成分为1-(2-羟乙基)-2-咪唑啉酮。
4.根据权利要求1或2所述的化妆品，其中，(A)成分的配合量相对于化妆品的总量为0.05～7质量％。
5.根据权利要求1或2所述的化妆品，其中，(B)成分的最大纤维直径为1000nm以下。
6.根据权利要求1或2所述的化妆品，其中，(B)成分的配合量相对于化妆品的总量为0.005～1质量％。
7.根据权利要求1或2所述的化妆品，其中，(A)成分的配合量相对于(B)成分的配合量即(A)/(B)以质量比计为1～300。
8.根据权利要求1或2所述的化妆品，其还包含(D)琥珀酰聚糖。
9.根据权利要求8所述的化妆品，其中，(D)成分的配合量相对于化妆品的总量为0.005～1质量％。
10.根据权利要求1或2所述的化妆品，其还包含(E)聚乙二醇。
11.根据权利要求10所述的化妆品，其中，(E)成分的配合量相对于化妆品的总量为0.1～5质量％。
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